Microtubule-stabilising drugs for therapy of Alzheimer's disease and other neurodegenerative disorders with axonal transport impairments

Expert Opinion on Pharmacotherapy

Volumn 6, Issue 5, 2005, Pages 683-686

  Trojanowski, John Q ^a   Smith, Amos B ^b   Huryn, Donna ^b   Lee, Virginia M Y ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Alzheimer's disease; Axonal transport; Microtubule binding drugs; Neurodegenerative

Indexed keywords

ALPHA SYNUCLEIN; AMYLOID PRECURSOR PROTEIN; COUMARIN DERIVATIVE; DICOUMAROL; DISCODERMOLIDE; DOCETAXEL; DYNACTIN; ELEUTHEROBIN; EPOTHILONE A; EPOTHILONE B; HUNTINGTIN; KINESIN; LAULIMALIDE; MOLECULAR MOTOR; NATURAL PRODUCT; PACLITAXEL; PACLITAXEL DERIVATIVE; PELORUSIDE; PRESENILIN 1; PRESENILIN 2; SARCODICTYIN A; SARCODICTYIN B; SUPEROXIDE DISMUTASE; TACCALONOLIDE; TAU PROTEIN; TERPENOID; TUBERCIDIN; UK 100; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; ANTINEOPLASTIC ACTIVITY; BLOOD BRAIN BARRIER; BRAIN DEGENERATION; DEGENERATIVE DISEASE; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG PENETRATION; DRUG POTENTIATION; EDITORIAL; EVIDENCE BASED MEDICINE; FAMILIAL DISEASE; FRONTOTEMPORAL DEMENTIA; HEREDITARY MOTOR SENSORY NEUROPATHY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MICROTUBULE ASSEMBLY; MOTOR NEURON DISEASE; MUTATIONAL ANALYSIS; NERVE FIBER TRANSPORT; NONHUMAN; PARKINSON DISEASE; PROTEIN AGGREGATION; PROTEIN FUNCTION; SPASTIC PARAPLEGIA;

ALZHEIMER DISEASE; ANIMALS; AXONAL TRANSPORT; HUMANS; MICROTUBULES; NEURODEGENERATIVE DISEASES; PACLITAXEL;

EID: 19044378780     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.6.5.683     Document Type: Editorial

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