Nitric oxide as a regulator of inflammatory processes

Memorias do Instituto Oswaldo Cruz

Volumn 100, Issue SUPPL. 1, 2005, Pages 5-9

  Wallace, John L ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

Endothelium; Macrophages; Mast cells; Neutrophils; Platelets

Indexed keywords

ACETYLSALICYLIC ACID; ACETYLSALICYLIC ACID DERIVATIVE; ANTIOXIDANT; AUTACOID; MESALAZINE; NITRIC OXIDE; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE INHIBITOR; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL; PREDNISOLONE; SUPEROXIDE DISMUTASE;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; BLOOD FLOW; CELL DAMAGE; CONFERENCE PAPER; DRUG EFFICACY; DRUG POTENCY; DRUG POTENTIATION; EDEMA; ENDOTHELIUM CELL; ENZYME ACTIVITY; GASTROINTESTINAL TOXICITY; INFLAMMATION; LEUKOCYTE; LEUKOCYTE ADHERENCE; MACROPHAGE; MAST CELL; MEDIATOR; MEDIATOR RELEASE; MUCOSA; NONHUMAN; REGULATORY MECHANISM; REPERFUSION INJURY; THROMBOCYTE; VASCULAR ENDOTHELIUM;

EID: 18844391239     PISSN: 00740276     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0074-02762005000900002     Document Type: Conference Paper

References (50)

1. Ahluwalia A, Foster P, Scotland RS, McLean PG, Mathur A, Perretti M, Moncada S, Hobbs AJ 2004. Anti-inflammatory activity of soluble guanylate cyclase: cGMP-dependent down-regulation of P-selectin expression and leukocyte recruitment. Proc Natl Acad Sci USA 101: 1386-1391.
2. Armstead VE, Minchenko AG, Schuhl RA, Hayward R, Nossuli TO, Lefer AM 1997. Regulation of P-selectin expression in human endothelial cells by nitric oxide. Am J Physiol 273: H740-H746.
3. Banick PD, Chen QP, Xu YA, Thom SR 1997. Nitric oxide inhibits neutrophil b2 integrin function by inhibiting membrane-associated cyclic GMP synthesis. J Cell Physiol 172: 12-24.
4. Beckman J, Koppenol W 1996. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and the ugly. Am J Physiol 271: C1424-C1437.
5. Bissonnette EY, Hogaboam CM, Wallace JL, Befus AD 1991. Potentiation of tumor necrosis factor-α-mediated cytotoxicity of mast cells by their production of nitric oxide. J Immunol 147: 3060-3065.
6. Cirino G, Wheeler-Jones CP, Wallace JL, Del Soldato P, Baydoun AR 1996. Inhibition of inducible nitric oxide synthase expression by novel nonsteroidal anti-inflammatory derivatives with gastrointestinal-sparing properties. Br J Pharmacol 117: 1421-1426.
7. Clancy R, Leszczynska-Piziak J, Abramson S 1992. Nitric oxide, and endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase. J Clin Invest 90: 1116-1121.
8. Davies NM, Roseth AG, Appleyard CB, McKnight W, Del Soldato P, Calignano A, Cirino G, Wallace JL 1997. NO-naproxen vs naproxen: ulcerogenic, analgesic and anti-inflammatory effects. Aliment Pharmacol Ther 11: 69-79.
9. Fiorucci S, Antonelli E, Distrutti E, Del Soldato P, Flower RJ, Clark MJ, Morelli A, Perretti M, Ignarro LJ 2002. NCX-1015, a nitric-oxide derivative of prednisolone, enhances regulatory T cells in the lamina propria and protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis in mice. Proc Natl Acad Sci USA 99: 15770-15775.
10. Fiorucci S, Antonelli E, Santucci L, Morelli O, Miglietti M, Federici B, Mannucci R, Del Soldato P, Morelli A 1999. Gastrointestinal safety of nitric oxide-derived aspirin is related to inhibition of ICE-like cysteine proteases in rats. Gastroenterology 116: 1089-1106.
11. Furchgott RF, Zawadzki JV 1980. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288: 373-376.
12. Gaboury J, Woodman RC, Granger DN, Reinhardt P, Kubes P 1993. Nitric oxide prevents leukocyte adherence: role of superoxide. Am J Physiol 265: H862-H867.
13. Gilchrist M, Hesslinger C, Befus AD 2003. Tetrahydrobiopterin, a critical factor in the production and role of nitric oxide in mast cells. J Biol Chem 278: 50607-50614.
14. Gryglewski RJ, Palmer RMJ, Moncada S 1986. Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor. Nature 320: 454-456.
15. Hinder F, Stubbe HD, Van Aken H, Waurick R, Booke M, Meyer J 1999. Role of nitric oxide in sepsis-associated pulmonary edema. Am J Respir Crit Care Med 159: 252-257.
16. Hogaboam CM, Befus AD, Wallace JL 1993. Modulation of rat mast cell reactivity by IL-1b: Divergent effects on nitric oxide and platelet-activating factor release. J Immunol 151: 3767-3774.
17. Huang FP, Niedbala W, Wei XQ, Xu D, Feng GJ, Robinson JH, Lam C, Liew FY 1998. Nitric oxide regulates Th1 cell development through the inhibition of IL-12 synthesis by macrophages. Eur J Immunol 28: 4062-4067.
18. Ignarro LJ, Buga GM, Wood KS, Byrns RE, Chaudhuri G 1987. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc Natl Acad Sci USA 84: 9265-9269.
19. Kanner J, Harel S, Granit R 1991. Nitric oxide as an antioxidant. Arch Biochem Biophys 289: 130-136.
20. Kanwar S, Wallace JL, Befus D, Kubes P 1994. Nitric oxide synthesis inhibition increases epithelial permeability via mast cells. Am J Physiol 266: G222-G229.
21. Katsuki S, Arnold W, Mittal C, Murad F 1977. Stimulation of guanylate cyclase by sodium nitroprusside, nitroglycerin and nitric oxide in various tissue preparations and comparison to the effects of sodium azide and hydroxylamine. J Cyclic Nucleotide Res 3: 23-35.
22. Katsuyama K, Shichiri M, Marumo F, Hirata Y 1998. NO inhibits cytokine-induced iNOS expression and NF-kappaB activation by interfering with phosphorylation and degradation of IkB-α. Arterioscler Thromb Vasc Biol 18: 1796-1802.
23. Krizanac-Bengez L, Kapural M, Parkinson F, Cucullo L, Hossain M, Mayberg MR, Janigro D 2003. Effects of transient loss of shear stress on blood-brain barrier endothelium: role of nitric oxide and IL-6. Brain Res 977: 239-246.
24. Kubes P, Kanwar S, Niu X-F, Gaboury JP 1993. Nitric oxide synthesis inhibition induces leukocyte adhesion via superoxide and mast cells. FASEB J 7: 1293-1299.
25. Kubes P, Suzuki M, Granger DN 1991. Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci USA 88: 4651-4655.
26. Masini E, Salvemini D, Pistelli A, Mannaioni PF, Vane JR 1991. Rat mast cells synthesize a nitric oxide like-factor which modulates the release of histamine. Agents Actions 33: 61-63.
27. May GR, Crook P, Moore PK, Page CP 1991. The role of nitric oxide as an endogenous regulator of platelet and neutrophil activation within the pulmonary circulation of the rabbit. Br J Pharmacol 102: 759-763.
28. Moncada S 1997. Nitric oxide in the vasculature: physiology and pathophysiology. Ann NY Acad Sci 811: 60-69.
29. Moncada S, Higgs EA 1995. Molecular mechanisms and therapeutic strategies related to nitric oxide. FASEB J 9: 1319-1330.
30. Moore PK, Marshall M 2003. Nitric oxide releasing acetaminophen (nitroacetaminophen). Dig Liver Dis 35 (Suppl. 2): S49-S60.
31. Mundy AL, Dorrington KL 2000. Inhibition of nitric oxide synthesis augments pulmonary oedema in isolated perfused rabbit lung. Br J Anaesth 85: 570-576.
32. Muscará MN, Wallace JL 1999. Nitric oxide V: therapeutic potential of nitric oxide donors and inhibitors. Am J Physiol 276: G1313-G1316.
33. Obermeier F, Gross V, Scholmerich J, Falk W 1999. Interleukin-1 production by mouse macrophages is regulated in a feedback fashion by nitric oxide. J Leukocyte Biol 66: 829-836.
34. Palacios-Callender M, Quintero M, Hollis VS, Springett RJ, Moncada S 2004. Endogenous NO regulates superoxide production at low oxygen concentrations by modifying the redox state of cytochrome c oxidase. Proc Natl Acad Sci USA 101: 7630-7635.
35. Palmer RMJ, Ferrige AG, Moncada S 1987. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327: 524-526.
36. Paul-Clark MJ, Roviezzo F, Flower RJ, Cirino G, Soldato PD, Adcock IM, Perretti M 2003. Glucocorticoid receptor nitration leads to enhanced anti-inflammatory effects of novel steroid ligands. J Immunol 171: 3245-3252.
37. Perretti M, Paul-Clark MJ, Mancini L, Flower RJ 2003. Generation of innovative anti-inflammatory and anti-arthritic glucocorticoid derivatives that release NO: the nitro-steroids. Dig Liver Dis 35 (Suppl. 2): S41-S48.
38. Perry MA, Wadhwa S, Parks DA, Pickard W, Granger DN 1986. Role of oxygen radicals in ischemia-induced lesions in the cat stomach. Gastroenterology 90: 362-367.
39. Persson J, Ekelund U, Grande PO 2003. Endogenous nitric oxide reduces microvascular permeability and tissue oedema during exercise in cat skeletal muscle. J Vasc Res 40: 538-546.
40. Rubanyi GM, Ho EH, Cantor EH, Lumma WC, Botelho LHP 1991. Cytoprotective function of nitric oxide: inactivation of superoxide radicals produced by human leukocytes. Biochem Biophys Res Commun 181: 1392-1397.
41. Salvemini D, Masini E, Anggard E, Mannaioni PF, Vane J 1990. Synthesis of a nitric oxide-like factor from L-arginine by rat serosal mast cells: stimulation of guanylate cyclase and inhibition of platelet aggregation. Biochem Biophys Res Commun 169: 596-601.
42. Salvemini D, Misko TP, Masferrer JL, Seibert K, Currie MG, Needleman P 1993. Nitric oxide activates cyclooxygenase enzymes. Proc Natl Acad Sci USA 90: 7240-7244.
43. Stuehr DJ, Marletta MA 1985. Mammalian nitrate bio-synthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide. Proc Natl Acad Sci USA 82: 7738-7742.
44. Van Overveld FJ, Bult H, Vermeire PA, Herman AG 1993. Nitroprusside, a nitrogen oxide generating drug, inhibits release of histamine and tryptase from human skin mast cells. Agents Actions 38 (Suppl. C): C237-C238.
45. Wallace JL, Ignarro LJ, Fiorucci S 2002. Potential cardio-protective actions of nitric oxide-releasing aspirin. Nature Reviews Drug Discov 1: 375-382.
46. Wallace JL, Elliott SN, Del Soldato P, McKnight W, Sannicolo F, Cirino G 1997. Gastrointestinal sparing anti-inflammatory drugs: the development of nitric oxide-relasing NSAIDs. Drug Develop Res 42: 144-149.
47. Wallace JL, Reuter B, Cicala C, McKnight W, Grisham MB, Cirino G 1994. Novel nonsteroidal anti-inflammatory drug derivatives with markedly reduced ulcerogenic properties in the rat. Gastroenterology 107: 173-179.
48. Wallace JL, Vergnolle N, Muscara MN, Asfaha S, Chapman K, McKnight W, Del Soldato P, Morelli A, Fiorucci S 1999. Enhanced anti-inflammatory effects of a nitric oxide-releasing derivative of mesalamine in rats. Gastroenterology 117: 557-566.
49. Ziehe M, Morbidelli L, Choudhuri R, Zhang HT, Donnini S, Granger HJ, Bicknell R 1997. Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor-induced angiogenesis. J Clin Invest 99: 2625-2634.
50. Zimmerman BJ, Grisham MB, Granger DN 1990. Role of oxidants in ischemia/reperfusion-induced granulocyte infiltration. Am J Physiol 258: G185-G190.