Endogenous Nitric Oxide Reduces Microvascular Permeability and Tissue Oedema during Exercise in Cat Skeletal Muscle

Journal of Vascular Research

Volumn 40, Issue 6, 2003, Pages 538-546

  Persson, Johan ^a   Ekelund, Ulf ^a   Grände, Per Olof ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Capillary filtration coefficient; Exercise hyperaemia; L NAME; Nitric oxide; Oedema; Prostacyclin; Skeletal muscle; Starling formula; Tranylcypromine; Vascular permeability

Indexed keywords

ENDOTHELIAL CONSTITUTIVE NITRIC OXIDE SYNTHASE; ENZYME INHIBITOR; MONOAMINE OXIDASE INHIBITOR; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; PROSTACYCLIN; TRANYLCYPROMINE; UNCLASSIFIED DRUG;

ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CAPILLARY PERMEABILITY; CAT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; EDEMA; EVALUATION; EXERCISE; GASTROCNEMIUS MUSCLE; HYDRAULIC PERMEABILITY; HYPEREMIA; LIGATION; LYMPH VESSEL; METABOLISM; MICROCIRCULATION; MICROVASCULATURE; MOTOR NERVE; MUSCLE INJURY; MUSCLE MASS; MYOPATHY; NERVE STIMULATION; NONHUMAN; PERFUSION; PHYSIOLOGY; PRIORITY JOURNAL; SKELETAL MUSCLE; TIME; TISSUE INJURY; VASCULAR RESISTANCE; VASCULARIZATION; VOLUMETRY;

ANIMALS; CAPILLARY PERMEABILITY; CATS; EDEMA; ENZYME INHIBITORS; EPOPROSTENOL; EXERTION; MICROCIRCULATION; MONOAMINE OXIDASE INHIBITORS; MUSCLE, SKELETAL; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; TRANYLCYPROMINE; VASCULAR RESISTANCE;

EID: 0442324629     PISSN: 10181172     EISSN: None     Source Type: Journal    
DOI: 10.1159/000075677     Document Type: Article

References (47)

1. Björnberg J: Forces involved in transcapillary fluid movement in exercising cat skeletal muscle. Acta Physiol Scand 1990;140:221-236.
2. Watson PD, Garner RP, Ward DS: Water uptake in stimulated cat skeletal muscle. Am J Physiol 1993;264:R790-R796.
3. Jacobsson S, Kjellmer I: Accumulation of fluid in exercising muscle. Acta Physiol Scand 1964;60:286-295.
4. Lundvall J, Mellander S, Westling H, White T: Fluid transfer between blood and tissues during exercise. Acta Physiol Scand 1972;85:258-269.
5. Convertino VA, Keil LC, Bernauer EM, Greenleaf JE: Plasma volume, osmolality, vasopressin, and renin activity during graded exercise in man. J Appl Physiol 1981;50:123-128.
6. Lundvall J: Tissue hyperosmolality as a mediator of vasodilatation and transcapillary fluid flux in exercising skeletal muscle. Acta Physiol Scand 1972;379:1-142.
7. Ward DS, Hamilton MT, Watson PD: Measurement of tissue volume during non-steady state high-intensity muscle contraction. Am J Physiol 1996;271:R1682-R1690.
8. Laughlin M, Korthuis R, Duncker D, Bache R: Control of blood flow to cardiac and skeletal muscle during exercise; in Rocoell LB, Sheperd JT (eds): Handbook of Physiology XII. Bethesda, American Physiological Society, 1996, pp 705-769.
9. Mellander S, Johansson B, Gray S, Jonsson O, Lundvall J, Ljung B: The effect of hyperosmolarity on intact and isolated vascular smooth muscle. Possible role in exercise hyperemia. Angiologica 1967;4:310-322.
10. Kjellmer I: The effect of exercise on the vascular bed of skeletal muscle. Acta Anaesthesiol Scand 1964;62:18-30.
11. Koller A, Dörnyei G, Kaley G: Flow-induced responses in skeletal muscle venules: Modulation by nitric oxide and prostaglandins. Am J Physiol 1998;275:H831-H836.
12. Balon TW, Nadler JL: Nitric oxide release is present from incubated skeletal muscle preparations. J Appl Physiol 1994;77:2519-2521.
13. Loscalzo J, Vita JA: Ischemia, hyperemia, exercise, and nitric oxide. Complex physiology and complex molecular adaptations. Circulation 1994;90:2556-2559.
14. Roberts CK, Barnard RJ, Jasman A, Balon TW: Acute exercise increases nitric oxide synthase activity in skeletal muscle. Am J Physiol 1999;277:E390-E394.
15. Kubes P: Nitric oxide modulates epithelial permeability in the feline small intestine. Am J Physiol 1992;262:G1138-G1142.
16. Möller AD, Grände P: Role of prostacyclin and nitric oxide in regulation of basal microvascular hydraulic permeability in cat skeletal muscle. J Vasc Res 1999;36:245-252.
17. Persson J, Ekelund U, Grände P-O: Nitric oxide and prostacyclin play a role in regulation of microvascular protein and hydraulic permeability in cat skeletal muscle. Microcirculation 2003;10:233-243.
18. i and microvascular permeability. Am J Physiol 1997;272:H176-H185.
19. Rumbaut RE, Wang J, Huxley VH: Differential effects of L-NAME on rat venular hydraulic conductivity. Am J Physiol Heart Circ Physiol 2000;279:H2017-H2023.
20. King-Vanvlack CE, Curtis SE, Mewburn JD, Cain SM, Chapler CK: Role of endothelial factors in active hyperemic responses in contracting canine muscle. J Appl Physiol 1995;79:107-112.
21. Kongstad L, Grände PO: The capillary filtration coefficient for evaluation of capillary fluid permeability in cat calf muscles. Acta Physiol Scand 1998;164:201-211.
22. Bentzer P, Kongstad L, Grände PO: Capillary filtration coefficient is independent of number of perfused capillaries in cat skeletal muscle. Am J Physiol 2001;280:H2697-H2706.
23. Bentzer P, Holbeck S, Grände PO: Endothelin-1 reduces microvascular fluid permeability through secondary release of prostacyclin in cat skeletal muscle. Microvasc Res 2002;63:50-60.
24. Rees DD, Palmer RM, Schulz R, Hodson HF, Moncada S: Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br J Pharmacol 1990;101:746-752.
25. Gryglewski RJ, Bunting S, Moncada S, Flower RJ, Vane JR: Arterial walls are protected against deposition of platelet thrombi by a substance (prostaglandin X) which they make from prostaglandin endoperoxides. Prostaglandins 1976;12:685-713.
26. Hester RL, Eraslan A, Saito Y: Differences in EDNO contribution to arteriolar diameters at rest and during functional dilation in striated muscle. Am J Physiol 1993;265:H146-H151.
27. Hirai T, Zelis R, Musch TI: Effects of nitric oxide synthase inhibition on the muscle blood flow response to exercise in rats with heart failure. Cardiovasc Res 1995;30:469-476.
28. Ekelund U, Björnberg J, Grände PO, Albert U, Mellander S: Myogenic vascular regulation in skeletal muscle in vivo is not dependent on endothelium-derived nitric oxide. Acta Physiol Scand 1992;144:199-207.
29. Persson MG, Gustafsson LE, Wiklund NP, Hedqvist P, Moncada S: Endogenous nitric oxide as a modulator of rabbit skeletal muscle microcirculation in vivo. Br J Pharmacol 1990;100:463-466.
30. Wilson JR, Kapoor S: Contribution of endothelium-derived relaxing factor to exercise-induced vasodilation in humans. J Appl Physiol 1993;75:2740-2744.
31. Folkow B, Halicka HD: A comparison between 'red' and 'white' muscle with respect to blood supply, capillary surface area and oxygen uptake during rest and exercise. Microvasc Res 1968;1:1-14.
32. Wolf MB, Porter LP, Watson PD: Effects of elevated venous pressure on capillary permeability in cat hindlimbs. Am J Physiol 1989;257:H2025-H2032.
33. Lundvall J, Länne T: Transmission of externally applied negative pressure to the underlying tissue. A study on the upper arm of man. Acta Physiol Scand 1989;136:403-409.
34. Cobbold A, Folkow I, Kjellmer S, Mellander S: Nervous and local chemical control of pre-capillary sphincters in skeletal muscle as measured by changes in filtration coefficient. Acta Physiol Scand 1963;57:180-192.
35. Folkow B, Mellander S: Measurements of capillary filtration coefficient and its use in studies of the control of capillary exchange; in Crone C, Lassen N (eds): Capillary Permeability: The Transfer of Molecules and Ions between Capillary Blood and Tissue. Copenhagen, Munksgaard, 1970, pp 614-623.
36. Rippe B, Folkow B: Simultaneous measurements of capillary filtration and diffusion capacities during graded infusions of noradrenaline (NA) and 5-hydroxytryptamine (5-HT) into the rat hindquarter vascular bed. Acta Physiol Scand 1980;109:265-273.
37. Rippe B, Haraldsson B: Transport of macromolecules across microvascular walls: The two-pore theory. Physiol Rev 1994;74:163-219.
38. Arturson G, Kjellmer I: Capillary permeability in skeletal muscle during rest and activity. Acta Physiol Scand 1964;62:41-45.
39. Baker CH, Davis DL: Isolated skeletal muscle blood flow and volume changes during contractile activity. Blood Vessels 1974;11:32-44.
40. Adamson RH, Liu B, Fry GN, Rubin LL, Curry FE: Microvascular permeability and number of tight junctions are modulated by cAMP. Am J Physiol 1998;274:H1885-H1894.
41. Ignarro LJ, Cirino G, Casini A, Napoli C: Nitric oxide as a signaling molecule in the vascular system: An overview. J Cardiovasc Pharmacol 1999;34:879-886.
42. Kubes P: Nitric oxide-induced microvascular permeability alterations: A regulatory role for cGMP. Am J Physiol 1993;265:H1909-H1915.
43. Kubes P, Kerfoot SM: Leukocyte recruitment in the microcirculation: The rolling paradigm revisited. News Physiol Sci 2001;16:76-80.
44. Coates G, O'Brodovich H, Goeree G: Hindlimb and lung lymph flows during prolonged exercise. J Appl Physiol 1993;75:633-638.
45. Kjellmer I: An indirect method for estimating tissue pressure with special reference to tissue pressure in muscle during exercise. Acta Physiol Scand 1964;62:31-40.
46. Sejersted OM, Hargens AR, Kardel KR, Blom P, Jensen O, Hermansen L: Intramuscular fluid pressure during isometric contraction of human skeletal muscle. J Appl Physiol 1984;56:287-295.
47. Åstrand P, Saltin B: Plasma and red cell volume after prolonged severe exercise. J Appl Physiol 1964;19:829-832.