Antiinflammatory activity of soluble guanylate cyclase: cGMP-dependent down-regulation of P-selectin expression and leukocyte recruitment

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 5, 2004, Pages 1386-1391

  Ahluwalia, Amrita ^a   Foster, Paul ^a   Scotland, Ramona S ^b   McLean, Peter G ^a   Mathur, Anthony ^a   Perretti, Mauro ^a   Moncada, Salvador ^b   Hobbs, Adrian J ^b  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Endothelium; Intravital microscopy

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 4 AMINO 5 CYCLOPROPYL 2 [1 (2 FLUOROBENZYL) 1H PYRAZOLO[3,4 B]PYRIDIN 3 YL]PYRIMIDINE; ANTIINFLAMMATORY AGENT; CYCLIC GMP; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENZYME ACTIVATOR; GUANYLATE CYCLASE; NITRIC OXIDE; PADGEM PROTEIN; SOLUBLE GUANYLATE CYCLASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL INTERACTION; CONTROLLED STUDY; DOWN REGULATION; FLUORESCENCE ACTIVATED CELL SORTING; KNOCKOUT MOUSE; LEUKOCYTE ROLLING; MALE; MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; VENULE;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL COMMUNICATION; CYCLIC GMP; DOWN-REGULATION; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; GUANYLATE CYCLASE; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-1; LEUKOCYTES; MALE; MICE; MICE, KNOCKOUT; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; P-SELECTIN; PYRAZOLES; PYRIDINES;

ANIMALIA;

EID: 0842299577     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0304264101     Document Type: Article

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