Input-specific targeting of NMDA receptor subtypes at mouse hippocampal CA3 pyramidal neuron synapses

Neuropharmacology

Volumn 39, Issue 6, 2000, Pages 943-951

  Ito, Isao ^a   Kawakami, Ryosuke ^a   Sakimura, Kenji ^b   Mishina, Masayoshi ^c   Sugiyama, Hiroyuki ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b Niigata University   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

CA3 synapse; Gene targeting; Hippocampus; NMDA receptors; NMDA subunits; Ro 25 6981

Indexed keywords

4 BENZYL ALPHA (4 HYDROXYPHENYL) BETA METHYL 1 PIPERIDINEPROPANOL; GLUTAMIC ACID; IFENPRODIL; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DENDRITE; DRUG EFFECT; DRUG RECEPTOR BINDING; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN TARGETING; PYRAMIDAL NERVE CELL; SYNAPSE;

ANIMALS; CELL POLARITY; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; HIPPOCAMPUS; LONG-TERM POTENTIATION; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; PHENOLS; PIPERIDINES; PYRAMIDAL CELLS; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPSES;

EID: 0034058261     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(99)00217-8     Document Type: Article

References (43)

1. Blake J.F., Brown M.W., Collingridge G.L. CNQX blocks acidic amino acid induced depolarizations and synaptic components mediated by non-NMDA receptors in rat hippocampal slices. Neuroscience Letters. 89:1988;182-186.
2. Blanton M.G., Lo Turco J.J., Kriegstein A.R. Whole cell recording from neurons in slices of reptilian and mammalian cerebral cortex. Journal of Neuroscience Methods. 30:1989;203-210.
3. Bliss T.V., Collingridge G.L. A synaptic model of memory: long-term potentiation in the hippocampus. Nature. 361:1993;31-39.
4. Carter C., Benavides J., Legendre P.et al. Ifenprodil and SL 82.0715 as cerebral anti-ischemic agents. II. Evidence for N-methyl-D-aspartate receptor antagonist properties. Journal of Pharmacology and Experimental Therapy. 247:1988;1222-1232.
5. Castillo P.E., Malenka R.C., Nicoll R.A. Kainate receptors mediate a slow postsynaptic current in hippocampal CA3 neurons. Nature. 388:1997;182-186.
6. Cline H.T., Debski E.A., Constantine-Paton M. N-methyl-D-aspartate receptor antagonist desegregates eye-specific stripes. Proceedings of the National Academy of Sciences of the USA. 84:1987;4342-4345.
7. Fischer G., Mutel V., Trube G., Malherbe P., Kew J.N., Mohacsi E., Heitz M.P., Kemp J.A. Ro 25-6981, a highly potent and selective blocker of N-methyl-D-aspartate receptors containing the NR2B subunit. Characterization in vitro. Journal of Pharmacology and Experimental Therapy. 283:1997;1285-1292.
8. A receptor subunits revealed by antigen-retrieval immunohistochemistry. Journal of Comparative Neurology. 390:1998;194-210.
9. Goodman C.S., Shatz C.J. Developmental mechanisms that generate precise patterns of neuronal connectivity. Cell. 72:1993;77-98.
10. Harris E.W., Cotman C.W. Long-term potentiation of guinea pig mossy fiber responses is not blocked by N-methyl-D-aspartate antagonists. Neuroscience Letters. 70:1986;132-137.
11. Hollmann M., Boulter J., Maron C., Beasley L., Sullivan J., Pecht G., Heinemann S. Zinc potentiates agonist-induced currents at certain splice variants of the NMDA receptor. Neuron. 10:1993;943-954.
12. Ikeda K., Nagasawa M., Mori H., Araki K., Sakimura K., Watanabe M., Inoue Y., Mishina M. Cloning and expression of the ε4 subunit of the NMDA receptor channel. FEBS Letters. 313:1992;34-38.
13. Isaac J.T., Nicoll R.A., Malenka R.C. Evidence for silent synapses: implications for the expression of LTP. Neuron. 15:1995;427-434.
14. Ishizuka N., Cowan W.M., Amaral D.G. A quantitative analysis of the dendritic organization of pyramidal cells in the rat hippocampus. Journal of Comparative Neurology. 362:1995;17-45.
15. Ishizuka N., Weber J., Amaral D.G. Organization of intrahippocampal projections originating from CA3 pyramidal cells in the rat. Journal of Comparative Neurology. 295:1990;580-623.
16. Ito I., Akashi K., Sakimura K., Mishina M., Sugiyama H. Distribution and development of NMDA receptor activities at hippocampal synapses examined using mice lacking the ε1 subunit gene. Neuroscience Research. 30:1998;119-123.
17. Ito I., Futai K., Katagiri H., Watanabe M., Sakimura K., Mishina M., Sugiyama H. Synapse-selective impairment of NMDA receptor functions in mice lacking NMDA receptor ε1 or ε2 subunit. Journal of Physiology (London). 500:1997;401-408.
18. Ito I., Sakimura K., Mishina M., Sugiyama H. Age-dependent reduction of hippocampal LTP in mice lacking N-methyl-D-aspartate receptor ε1 subunit. Neuroscience Letters. 203:1996;69-71.
19. Katsuki H., Kaneko S., Tajima A., Satoh M. Separate mechanisms of long-term potentiation in two input systems to CA3 pyramidal neurons of rat hippocampal slices as revealed by the whole-cell patch-clamp technique. Neuroscience Research. 12:1991;393-402.
20. Kew J.N.C., Richards J.G., Mutel V., Kemp J.A. Developmental changes in, NMDA receptor glycine affinity and ifenprodil sesitivity reveal three distinct populations of NMDA receptors in individual rat cortical neurons. Journal of Neuroscience. 18:1998;1935-1943.
21. Keynes R., Cook G.M. Axon guidance molecules. Cell. 83:1995;161-169.
22. Kiyama Y., Manabe T., Sakimura K., Kawakami F., Mori H., Mishina M. Increased thresholds for long-term potentiation and contextual learning in mice lacking the NMDA-type glutamate receptor ε1 subunit. Journal of Neuroscience. 18:1998;6704-6712.
23. Kleinschmidt A., Bear M.F., Singer W. Blockade of "NMDA" receptors disrupts experience-dependent plasticity of kitten striate cortex. Science. 238:1987;355-358.
24. Kutsuwada T., Kashiwabuchi N., Mori H.et al. Molecular diversity of the NMDA receptor channel. Nature. 358:1992;36-41.
25. Kutsuwada T., Sakimura K., Manabe T.et al. Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor ε2 subunit mutant mice. Neuron. 16:1996;333-344.
26. Liao D., Hessler N.A., Malinow R. Activation of postsynaptically silent synapses during pairing-induced LTP in CA1 region of hippocampal slice. Nature. 375:1995;400-404.
27. Malenka R.C., Nicoll R.A. NMDA-receptor-dependent synaptic plasticity: multiple forms and mechanisms. Trends in Neuroscience. 16:1993;521-527.
28. Meguro H., Mori H., Araki K.et al. Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs. Nature. 357:1992;70-74.
29. Monyer H., Sprengel R., Schoepfer R.et al. Heteromeric NMDA receptors: molecular and functional distinction of subtypes. Science. 256:1992;1217-1221.
30. Mori H., Mishina M. Structure and function of the NMDA receptor channel. Neuropharmacology. 34:1995;1219-1237.
31. Moriyoshi K., Masu M., Ishii T., Shigemoto R., Mizuno N., Nakanishi S. Molecular cloning and characterization of the rat NMDA receptor. Nature. 354:1991;31-37.
32. Mott D.D., Doherty J.J., Zhang S., Washburn M.S., Fendley M.J., Lyuboslavsky P., Traynelis S.F., Dingledine R. Phenylethanolamines inhibit NMDA receptors by enhancing proton inhibition. Nature Neuroscience. 1:1998;659-667.
33. 3H]Ro 25-6981, a potent and selective antagonist of NMDA receptors containing NR2B subunits. Journal of Neurochemistry. 70:1998;2147-2155.
34. Nagasawa M., Sakimura K., Mori K.J., Bedell M.A., Copeland N.G., Jenkins N.A., Mishina M. Gene structure and chromosomal localization of the mouse NMDA receptor channel subunits. Brain Research and Molecular Brain Research. 36:1996;1-11.
35. Sakimura K., Kutsuwada T., Ito I.et al. Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor ε1 subunit. Nature. 373:1995;151-155.
36. Seeburg P.H. The TINS/Tips Lecture. The molecular biology of mammalian glutamate receptor channels. Trends in Neuroscience. 16:1993;359-365.
37. Tovar K.R., Westbrook G.L. The incorporation of NMDA receptors with a distinct subunit composition at nascent hippocampal synapses in vitro. Journal of Neuroscience. 19:1999;4180-4188.
38. Vignes M., Collingridge G.L. The synaptic activation of kainate receptors. Nature. 388:1997;179-182.
39. Watanabe M., Fukaya M., Sakimura K., Manabe T., Mishina M., Inoue Y. Selective scarcity of NMDA receptor channel subunits in the stratum lucidum (mossy fibre-recipient layer) of the mouse hippocampal CA3 Subfield. European Journal of Neuroscience. 10:1998;478-487.
40. Watanabe M., Inoue Y., Sakimura K., Mishina M. Developmental changes in distribution of NMDA receptor channel subunit mRNAs. Neuroreport. 3:1992;1138-1140.
41. Watanabe M., Inoue Y., Sakimura K., Mishina M. Distinct distributions of five N-methyl-D-aspartate receptor channel subunit mRNAs in the forebrain. Journal of Comparative Neurology. 338:1993;377-390.
42. Williams K., Russell S.L., Shen Y.M., Molinoff P.B. Developmental switch in the expression of NMDA receptors occurs in vivo and in vitro. Neuron. 10:1993;267-378.
43. Yamazaki M., Mori H., Araki K., Mori K.J., Mishina M. Cloning, expression and modulation of a mouse NMDA receptor subunit. FEBS Letters. 300:1992;39-45.