Role of Bag-1 in the survival and proliferation of the cytokine- dependent lymphocyte lines, Ba/F3 and Nb2

Molecular Endocrinology

Volumn 11, Issue 5, 1997, Pages 608-618

  Clevenger, Charles V ^a   Thickman, Karen ^a   Ngo, Winnie ^a   Chang, Wan Pin ^a   Takayama, Shinichi ^b   Reed, John C ^b  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^b BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; GLUCOCORTICOID; INTERLEUKIN 3; PROTEIN BCL 2; RAF PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DIAGNOSIS; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; RECEPTOR UPREGULATION;

EID: 0030893637     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.11.5.9925     Document Type: Article

References (78)

1. Williams GT, Smith CA, Spooncer E, Dexter TM, Taylor DR 1990 Hemopoietic colony stimulating factors promote cell survival by suppressing apoptosis. Nature 343:76-79
2. Wyllie AH 1980 Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284:555-556
3. Kerr JFR, Wyllie AH, Currie AR 1972 Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26:239-257
4. Schrader JW, Thomson A (eds) 1994 Interleukin 3. In: The Cytokine Handbook, ed 2. Academic Press, San Diego, chapter 5, pp 81-98
5. Iscove NN, Shaw AR, Keller G 1989 Net increase of pluripotential hematopoietic precursors in suspension culture in response to IL1 and IL3. J Immunol 142:2332-2337
6. Yanagida M, Fukamachi H, Ohgami K, Kuwaki T, Ishii H, Uzamaki H, Amano K, Tokiwa T, Mitsui H, Saito H, et al. 1995 Effects of T-helper 2-type cytokines, interleukin-3 (IL3), IL4, IL5, and IL6 on the survival of cultured human mast cells. Blood 86:3705-3714
7. Pelligrini I, Lebrun J-J, Ali S, Kelly PA 1992 Expression of prolactin and its receptor in human lymphoid cells. Mol Endocrinol 6:1023-1031
8. Hartmann DP, Holoday JW, Bernton EW 1989 Inhibition of lymphocyte proliferation by antibodies to prolactin. FASEB J 3:2194-2202
9. Clevenger CV, Russell DH, Appasamy PM, Prystowsky MB 1990 Regulation of IL2-driven T-lymphocyte proliferation by prolactin. Proc Natl Acad Sci USA 87:6460-6464
10. Clevenger CV, Altmann SW, Prystowsky MB 1991 Requirement of nuclear prolactin for interleukin-2-stimulated proliferation of T lymphocytes. Science 253:77-79
11. Bernton EW, Meltzer MS, Holaday JW 1988 Suppression of macrophage activation and T-lymphocyte function in hypoprolactinemic mice. Science 239:401-404
12. Benedetto N, Folgore A, Galdiero M, Meli R, DiCarol R 1995 Effect of prolactin, rIFN-gamma or rTNF-alpha in murine toxoplasmosis. Pathol Biol 43:395-400
13. Di Carlo R, Meli R, Galdiero M, Nuzzo I, Bentivoglio C, Carratelli CR 1993 Prolactin protection against lethal effects of salmonella typhimurium. Life Sci 53:981-989
14. Clevenger CV, Sillman AL, Hanley-Hyde J, Prystowsky MB 1992 Requirement for prolactin during cell cycle regulated gene expression in cloned T-lymphocytes. Endocrinology 130:3216-3222
15. Schwarz LA, Stevens AM, Hrachovy JA, Yu-Lee L-Y 1992 Interferon regulatory factor-1 is inducible by prolactin, interleukin-2 and concanavalin A in T cells. Mol Cell Endocrinol 86:103-110
16. Fletcher-Chiappini SE, Comptom MM, Lavoie HA, Day EB, Witorsch RJ 1993 Glucocorticoid-prolactin interactions in Nb2 lymphoma cells: antiproliferative vs. anticytolytic effects. Proc Soc Exptl Biol Med 202:345-352
17. Witorsch RJ, Day EB, Lavoie HA, Hashemi N, Taylor JK 1993 Comparison of glucocorticoid-induced effects in prolactin-dependent and autonomous rat Nb2 lymphoma cells. Proc Soc Exp Biol Med 203:454-460
18. Lavoie HA, Witorsch RJ 1995 Investigation of intracellular signals mediating the anti-apoptotic action of prolactin in Nb2 lymphoma cells. Proc Soc Exp Biol Med 209:257-269
19. Alderson MR, Tough TW, Davis-Smith T, Braddy S, Falk B, Schooley KA, Goodwin RG, Smith CA, Tamsdell F, Lynch DH 1995 Fas ligand mediates activation-induced cell death in human T-lymphocytes. J Exp Med 181:71-77
20. Linette GP, Korsmeyer SJ 1994 Differentiation and cell death: lessons from the immune system. Curr Opin Cell Biol 6:809-815
21. Reed JC 1994 Bcl-2 and the regulation of programmed cell death. J Cell Biol 124:1-6
22. Boise LH, Gottschalk AR, Quintans J, Thompson CB 1995 Bcl-2 and Bcl-2-related proteins in apoptosis regulation. Curr Top Microbiol Immunol 200:107-121
23. Dhein J, Salczak H, Baumler C, Debatin K-M, Krammer PH 1995 Autocrine T-cell suicide mediated by APO-1/ (Fas/CD95). Nature 373:438-441
24. Ju ST, Panka DJ, Cui H, Ettinger R, El-Khatib M, Sherr DH, Stanger BZ, Marshak-Rothstein A 1995 Fas(CD95)/ FasL interaction required for programmed cell death after T-cell activation. Nature 373:444-448
25. Liu YJ, Joshua DE, Williams GT, Smith CA, Gordon J, Maclennan ICM 1989 Mechanism of antigen-driven selection in germinal centers. Nature 342:929-931
26. Smyth MJ 1995 Dual mechanisms of lymphocyte-mediated cytotoxicity serve to control and deliver the immune response. Bioessays 17:891-898
27. Merino R, Ding L, Veis DJ, Korsmeyer SJ, Nunez G 1994 Developmental regulation of the Bcl-2 protein and susceptibility to cell death in B lymphocytes. EMBO J 13:683-691
28. Zubiaga AM, Munoz E, Huber BT 1992 IL4 and IL2 selectively rescue Th cell subsets from glucocorticoid-induced apoptosis. J Immunol 149:107-112
29. Thompson EB 1994 Apoptosis and steroid hormones. Mol Endocrinol 8:665-673
30. Migliorati G, Nicoletti I, Pagliacci MC, D'Adamio L, Riccardi C 1993 Interleukin-4 protects double-negative and CD4 single-positive thymocytes from dexamethasone-induced apoptosis. Blood 81:1352-1358
31. Miyashita T, Reed JC 1992 Bcl-2 gene transfer increases relative resistance of S49.1 and WEHI7.2 lymphoid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs. Cancer Res 52:5407-5411
32. Wang H-G, Millan JA, Cox A, Der CJ, Rapp UR, Beck T, Zha H, Reed JC 1996 R-ras promotes apoptosis caused by growth factor deprivation via a Bcl-2 suppressible mechanism. J Cell Biol 129:1103-1114
33. Nunez G, London L, Hockenberry D, Alexander M, McKeam JP, Korsemeyer SJ 1990 Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines. J Immunol 144:3602-3610
34. Marvel J, Perkins GR, Rivas AL, Collins MKL 1994 Growth factor starvation of Bcl-2 overexpressing murine bone marrow cells induce refractoriness to IL-3 stimulation of proliferation. Oncogene 9:1117-1122
35. Stellar H 1995 Mechanisms and genes of cellular suicide. Science 267:1445-1449
36. Oltvai ZN, Millman CL, Korsmeyer SJ 1993 Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death. Cell 74:609-619
37. Hanada M, Aime-Sempe C, Sato T, Reed JC 1995 Structure-function analysis of Bcl-2 protein. J Biol Chem 270:11962-11969
38. Sedlak TW, Oltvai ZN, Yang E, Wang K, Boise LH, Thomspon CB, Korsmeyer SJ 1995 Multiple Bcl-2 family members demonstrate selective dimerizations with Bax. Proc Natl Acad Sci USA 92:7834-7838
39. Takayama S, Sato T, Krajewski S, Kochei K, Irie S, Millan JA, Reed JC 1995 Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity. Cell 80:279-284
40. Gout PW, Beer CT, Noble RL 1980 Prolactin-stimulated growth of cell cultures established from malignant Nb rat lymphomas. Cancer Res 40:2433-2436
41. Horsman DE, Masui S, Gout PW 1991 Karyotypic changes associated with loss of prolactin dependency of rat Nb2 node lymphoma cell cultures. Cancer Res 51:282-287
42. Bazan JF 1990 Structural design and molecular evolution of a cytokine receptor superfamily. Proc Natl Acad Sci USA 87:6934-6938
43. Ihle JN 1995 Cytokine receptor signaling. Nature 377:591-594
44. Horseman ND, Yu-Lee L-Y 1994 Transcriptional regulation by the helix bundle peptide hormones: growth hormone, prolactin, and hematopoietic cytokines. Endocr Rev 15:627-649
45. Witthuhn BA, Quelle FW, Silvennoinen O, Yi T, Tang B, Miura O, Ihle JN 1993 JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin. Cell 74:227-236
46. Silvennoinen O, Witthuhn BA, Quelle FW, Cleveland JL, Yi T, Ihle JN 1993 Structure of the murine Jak2 protein tyrosine-kinase and its role in interleukin 3 signal transduction. Proc Natl Acad Sci USA 90:8429-8433
47. c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region. Mol Cell Biol 14:4335-4341
48. Sato N, Sakamaki K, Terada N, Arai K, Miyajima A 1993 Signal transduction by the high-affinity GM-CSF receptor: two distinct regions of the common beta subunit responsible for different signaling. EMBO J 12: 4181-4189
49. Satoh T, Nakafuku M, Miyajima A, Kaziro Y 1991 Involvement of ras p21 protein in signal-transduction pathways for interleukin2, interleukin3, and granulocyte/macrophage colony-stimulating factor, but not from interleukin 4. Proc Natl Acad Sci USA 88:3314-3318
50. Welham MJ, Duronio V, Sanghera JS, Pelech SL, Schrader JW 1992 Multiple hemopoietic growth factors stimulate activation of mitogen-activated protein kinase family members. J Immunol 149:1683-1693
51. Vaux DL, Cory S, Adams JM 1988 Bcl-2 gene promotes hemopoietic survival and cooperates with c-myc to immortalize pre-B cells. Nature 335:440-442
52. Katsumata M, Siegel RM, Louie DC, Miyashita T, Tsujimoto Y, Nowell PC, Greene MI, Reed JC 1992 Differential effects of Bcl-2 on T and B cells in transgenic mice. Proc Natl Acad Sci USA 89:11376-11380
53. McDonnell TJ, Deane N, Platt FM, Nunez G, Jaeger U, McKeran JP, Korsmeyer SJ 1989 Bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation. Cell 57:79-88
54. Leff MA, Buckley DJ, Krumenacker JS, Reed JC, Miyashita T, Buckley AR 1996 Rapid modulation of the apoptosis regulatory genes, bcl-2 and bax by prolactin in rat Nb2 lymphoma cells. Endocrinology 137:5456-5462
55. Seth A, Gonzalez FA, Gupta S, Raden DL, Davis RJ 1992 Signal transduction within the nucleus by mitogen-activated protein kinase. J Biol Chem 267:24796-24804
56. Lange-Carter CA, Pleiman CM, Gardner AM, Blumer KJ, Johnson GL 1993 A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf. Science 260:315-319
57. Kyriakis JM, App H, Zhang X-F, Banerjee P, Brautigan DL, Rapp UR, Avruch J 1992 Raf-1 activates MAP kinase-kinase. Nature 358:417-421
58. Huang W, Alessandrini A, Crews CM, Erikson RL 1993 Raf-1 forms a stable complex with Mek1 and activates Mek1 by serine phosphorylation. Proc Natl Acad Sci USA 90:10947-51
59. Force T, Bonventure JV, Heidecker G, Rapp U, Avruch J, Kyriakis JM 1994 Enzymatic characteristics of the c-Raf-1 protein kinase. Proc Natl Acad Sci USA 91:1270-4
60. Wang H-G, Takayama S, Rapp UR, Reed JC 1996 Bcl-2 interacting protein, Bag-1, binds to and activates the kinase Raf-1. Proc Natl Acad Sci USA 93:7063-7068
61. v-ras cooperate in the activation of mitogen-activated protein kinase. Proc Natl Acad Sci USA 90:5772-5776
62. Dickson B, Sprenger F, Morrison D, Hafen E 1992 Raf functions downstream of Ras1 in the Sevenless signal transduction pathway. Nature 360:600-603
63. Van Aelst L, Barr M, Marcus S, Polverino A, Wigler M 1993 Complex formation between RAS and RAF and other protein kinases. Proc Natl Acad Sci USA 90:6213-6217
64. Leevers SJ, Paterson HF, Marshall CJ 1994 Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane. Nature 369:411-414
65. Wang H-G, Miyashita T, Takayama S, Sato T, Torigoe T, Krajewski S, Tanaka S, Hovey L, Troppmair J, Rapp U, et al. 1994 Apoptosis regulation by interaction of Bcl-2 protein and Raf-1 kinase. Oncogene 9:2751-2756
66. Troppmair J, Cleveland JL, Askew DS, Rapp UR 1992 v-raf/v-myc synergism in abrogation of IL-3 dependence: v-raf suppresses apoptosis. Curr Top Microbiol Immunol 182:453-459
67. Krajewski S, Tanaka S, Takayama S, Schibler MJ, Fenton W, Reed JC 1993 Investigation of the subcellular distribution of the bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes. Cancer Res 53:4701-14
68. Kant GJ, Bauman RA, Anderson SM, Mougey EH 1992 Effects of controllable vs. uncontrollable chronic stress on stress-responsive plasma hormones. Physiol Behav 51:1285-1288
69. Prystowsky MB, Clevenger CV 1994 Prolactin as a second messenger for interleukin 2. Immunomethods 5:49-55
70. Zellweger R, Wichman MW, Ayala A, DeMaso CM, Chaudry IH 1996 Prolactin: a novel and safe immunomodulating hormone for the treatment of immunodepression following sever hemorrhage. J Surg Res 63:53-58
71. Clevenger CV, Torigoe T, Reed JC 1994 Prolactin induces rapid phosphorylation and activation of prolactin receptor associated Raf-1 kinase in a T-cell line. J Biol Chem 269:5559-5565
72. Erwin RA, Kirken RA, Malbarba MG, Farrar WL, Rui H 1995 Prolactin activates Ras via signaling proteins SHC, growth factor receptor bound 2, and son of sevenless. Endocrinology 136:3512-3518
73. Clevenger CV, Ngo W, Luger SM, Gewirtz AM 1995 Vav is necessary for prolactin-stimulated proliferation and is translocated into the nucleus of a T-cell line. J Biol Chem 270:13246-13253
74. Chang W-P, Clevenger CV 1996 Modulation of growth factor receptor function by isoform heterodimerization. Proc Natl Acad Sci USA 93:5947-5952
75. Li X, Traganos F, Melamed MR, Darzynkeiwicz Z 1995 Single-step procedure for labeling DNA strand breaks with fluorescein- or BODIPY-conjugated deoxynucleotides: detection of apoptosis and bromodeoxyuridine incorporation. Cytometry 20:172-180
76. Brunetti M, Martelli N, Colasante A, Piantelli M, Musiani P, Aiello F 1995 Spontaneous and glucocorticoid-induced apoptosis in human mature T lymphocytes. Blood 86:4199-4205
77. Clevenger CV, Epstein AL, Bauer KD 1985 A method for simultaneous nuclear immunofluorescence and DNA content quantitation using monoclonal antibodies and flow cytometry. Cytometry 6:208-214
78. Baker SJ, Markowitz S, Fearon ER, Willson JKV, Vogelstein B 1990 Suppression of human colorectal carcinoma cell growth by wild-type p53. Science 249:912-915