Macrophage-derived chemokine gene transfer results in tumor regression in murine lung carcinoma model through efficient induction of antitumor immunity

Gene Therapy

Volumn 9, Issue 12, 2002, Pages 793-803

  Guo, J ^a   Wang, B ^b   Zhang, M ^a   Chen, T ^a   Yu, Y ^a   Regulier, E ^c   Homann, H E ^c   Qin, Z ^a   Ju, D W ^a   Cao, X ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b JINAN MILITARY GENERAL HOSPITAL   (China)

^c TRANSGENE S A   (France)

Author keywords

CTL; Dendritic cells; Gene therapy; IL 4; Macrophage derived chemokine

Indexed keywords

ADENOVIRUS VECTOR; BETA LACTAMASE; CD4 ANTIGEN; CD8 ANTIGEN; CHEMOATTRACTANT; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 2; INTERLEUKIN 4; MACROPHAGE DERIVED CHEMOKINE; MONOCLONAL ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLOOD LEVEL; CANCER MODEL; CELL ACTIVATION; CELL MIGRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; GENE TRANSFER; GENETIC CODE; HUMAN; HUMAN CELL; LUNG CARCINOMA; LYMPHATIC DRAINAGE; MALE; MOUSE; NONHUMAN; PERIPHERAL BLOOD STEM CELL; PRIORITY JOURNAL; SPLEEN; T LYMPHOCYTE; TISSUE LEVEL; TUMOR IMMUNITY; TUMOR LOCALIZATION; TUMOR REGRESSION; VIRAL GENE DELIVERY SYSTEM; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CHEMOKINES, CC; DENDRITIC CELLS; GENE THERAPY; GENETIC VECTORS; INJECTIONS, INTRALESIONAL; INTERFERON TYPE II; INTERLEUKIN-12; INTERLEUKIN-2; INTERLEUKIN-4; LUNG NEOPLASMS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEOPLASMS, EXPERIMENTAL; T-LYMPHOCYTES, CYTOTOXIC; TRANSFECTION;

ADENOVIRIDAE; ANIMALIA; MURINAE;

EID: 18444400845     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301688     Document Type: Article

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