Examination of the kinetic mechanism of mitogen-activated protein kinase activated protein kinase-2

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology

Volumn 1598, Issue 1-2, 2002, Pages 88-97

  Schindler, John F ^a   Godbey, Andrew ^a   Hood, William F ^a   Bolten, Suzanne L ^a   Broadus, Richard M ^a   Kasten, Thomas P ^a   Cassely, Aaron J ^a   Hirsch, Jeffery L ^a   Merwood, Michelle A ^a   Nagy, Mark A ^a   Fok, Kam F ^a   Saabye, Matthew J ^a   Morgan, Heidi M ^a   Compton, Robert P ^a   Mourey, Robert J ^a   Wittwer, Arthur J ^a   Monahan, Joseph B ^a  

^a PFIZER INC   (United States)

Author keywords

Biacore; Kinetics; MAPKAPK2; Surface plasmon resonance

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENYLYLIMIDODIPHOSPHATE; LEUCYLLYSYLARGINYLSERYLLEUCYLSERYLGLUTAMYLMETHIONINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE ACTIVATED PROTEIN KINASE 2; PEPTIDE; SERUM RESPONSE FACTOR; STAUROSPORINE DERIVATIVE; UNCLASSIFIED DRUG; ADENOSINE DIPHOSPHATE; ENZYME INHIBITOR; PROTEIN KINASE;

ARTICLE; COMPLEX FORMATION; ENZYME BINDING; KINETICS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SURFACE PLASMON RESONANCE; COMPETITIVE INHIBITION; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME ASSAY; ENZYME INHIBITION; ENZYME KINETICS; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; HUMAN; HUMAN CELL; REACTION ANALYSIS; VELOCITY;

AMINO ACID SEQUENCE; BINDING SITES; CLONING, MOLECULAR; ENZYME ACTIVATION; HUMANS; KINETICS; PEPTIDE FRAGMENTS; PEPTIDE MAPPING; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT FUSION PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUBSTRATE SPECIFICITY;

EID: 18444389741     PISSN: 01674838     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0167-4838(02)00340-0     Document Type: Article

References (42)