메뉴 건너뛰기




Volumn 28, Issue 3, 2004, Pages 421-427

Pharmacological studies with endogenous enhancer substances: β-phenylethylamine, tryptamine, and their synthetic derivatives

Author keywords

Phenylethylamine (PEA); ( ) 1 (benzofuran 2 yl) 2 propylaminopentane; ( ) 1 (Benzofuran 2 yl) 2 propylaminopentane ( ) BPAP ; ( ) BPAP; ( ) Deprenyl (Selegiline); Enhancer regulation; Enhancer substances; MAO; Trace amines; Tryptamine

Indexed keywords

AMINE; MONOAMINE OXIDASE INHIBITOR; PHENETHYLAMINE; SELEGILINE; TRYPTAMINE;

EID: 1842839793     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2003.11.016     Document Type: Review
Times cited : (47)

References (66)
  • 1
    • 0026308236 scopus 로고
    • Selegiline in de novo parkinsonian patients: The French selegiline multicenter trial (FSMP)
    • Allain H., Gougnard J., Naukirek H.C. Selegiline in de novo parkinsonian patients: the French selegiline multicenter trial (FSMP). Acta Neurol. Scand. 136:1991;73-78.
    • (1991) Acta Neurol. Scand. , vol.136 , pp. 73-78
    • Allain, H.1    Gougnard, J.2    Naukirek, H.C.3
  • 2
    • 0037330091 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled trial of the safety and efficacy of selegiline transdermal system without dietary restrictions in patients with major depressive disorder
    • Amsterdam J.D. A double-blind, placebo-controlled trial of the safety and efficacy of selegiline transdermal system without dietary restrictions in patients with major depressive disorder. J. Clin. Psychiatry. 64:2003;208-214.
    • (2003) J. Clin. Psychiatry , vol.64 , pp. 208-214
    • Amsterdam, J.D.1
  • 3
    • 0017345412 scopus 로고
    • Implications of combined treatment with "madopar" and L-deprenil in Parkinson's disease
    • Birkmayer W., Riederer P., Ambrozi L., Youdim M.B.H. Implications of combined treatment with "madopar" and L-deprenil in Parkinson's disease. Lancet. 1:1977;439-443.
    • (1977) Lancet , vol.1 , pp. 439-443
    • Birkmayer, W.1    Riederer, P.2    Ambrozi, L.3    Youdim, M.B.H.4
  • 4
  • 5
    • 0036842756 scopus 로고    scopus 로고
    • Transdermal selegiline in major depression: A double-blind, placebo-controlled, parallel-group study in outpatients
    • Bodkin J.A., Amsterdam J.D. Transdermal selegiline in major depression: a double-blind, placebo-controlled, parallel-group study in outpatients. Am. J. Psychiatry. 159:2002;1869-1875.
    • (2002) Am. J. Psychiatry , vol.159 , pp. 1869-1875
    • Bodkin, J.A.1    Amsterdam, J.D.2
  • 10
    • 0024384740 scopus 로고
    • Functional interactions of 2-phenylethylamine and of tryptamine with brain catecholamines: Implications for psychotherapeutic drug action
    • Greenshaw A.J. Functional interactions of 2-phenylethylamine and of tryptamine with brain catecholamines: implications for psychotherapeutic drug action. Prog. Neuro-Psychopharmacol. Biol. Psychiatry. 13:1989;431-443.
    • (1989) Prog. Neuro-Psychopharmacol. Biol. Psychiatry , vol.13 , pp. 431-443
    • Greenshaw, A.J.1
  • 11
    • 0033711865 scopus 로고    scopus 로고
    • (-)1-(Benzofuran-2-yl)-2-propylaminopentane shows survival effect on cortical neurons under serum-free condition through sigma receptors
    • Hamabe W., Fujita R., Yasusa T., Yoneda F., Yoshida A., Ueda H. (-)1-(Benzofuran-2-yl)-2-propylaminopentane shows survival effect on cortical neurons under serum-free condition through sigma receptors. Cell. Mol. Neurobiol. 20:2000;695-702.
    • (2000) Cell. Mol. Neurobiol. , vol.20 , pp. 695-702
    • Hamabe, W.1    Fujita, R.2    Yasusa, T.3    Yoneda, F.4    Yoshida, A.5    Ueda, H.6
  • 14
    • 0028146521 scopus 로고
    • Memories of my 45 years in research
    • Knoll J. Memories of my 45 years in research. Pharmacol. Toxicol. 75:1994;65-72.
    • (1994) Pharmacol. Toxicol. , vol.75 , pp. 65-72
    • Knoll, J.1
  • 15
    • 0031907334 scopus 로고    scopus 로고
    • (-)Deprenyl (selegiline), a catecholaminergic activity enhancer (CAE) substance acting in the brain
    • Knoll J. (-)Deprenyl (selegiline), a catecholaminergic activity enhancer (CAE) substance acting in the brain. Pharmacol. Toxicol. 82:1998;57-66.
    • (1998) Pharmacol. Toxicol. , vol.82 , pp. 57-66
    • Knoll, J.1
  • 16
    • 0035679477 scopus 로고    scopus 로고
    • Antiaging compounds: (-)Deprenyl (Selegiline) and (-)1-(benzofuran-2-yl)- 2-propylaminopentane, (-)BPAP, a selective highly potent enhancer of the impulse propagation mediated release of catecholamines and serotonin in the brain
    • Knoll J. Antiaging compounds: (-)Deprenyl (Selegiline) and (-)1-(benzofuran-2-yl)-2-propylaminopentane, (-)BPAP, a selective highly potent enhancer of the impulse propagation mediated release of catecholamines and serotonin in the brain. CNS Drug Rev. 7:2001;317-345.
    • (2001) CNS Drug Rev. , vol.7 , pp. 317-345
    • Knoll, J.1
  • 17
    • 0037709764 scopus 로고    scopus 로고
    • Enhancer regulation/endogenous and synthetic enhancer compounds: A neurochemical concept of the innate and acquired drives
    • Knoll J. Enhancer regulation/endogenous and synthetic enhancer compounds: a neurochemical concept of the innate and acquired drives. Neurochem. Res. 28:2003;1187-1209.
    • (2003) Neurochem. Res. , vol.28 , pp. 1187-1209
    • Knoll, J.1
  • 18
    • 0015274536 scopus 로고
    • Some puzzling effects of monoamine oxidase inhibitors
    • Knoll J., Magyar K. Some puzzling effects of monoamine oxidase inhibitors. Adv. Biochem. Psychopharmacol. 5:1972;393-408.
    • (1972) Adv. Biochem. Psychopharmacol. , vol.5 , pp. 393-408
    • Knoll, J.1    Magyar, K.2
  • 19
    • 0028816788 scopus 로고
    • Enhanced catecholaminergic and serotoninergic activity in rat brain from weaning to sexual maturity: Rationale for prophylactic (-)deprenyl (selegiline) medication
    • Knoll J., Miklya I. Enhanced catecholaminergic and serotoninergic activity in rat brain from weaning to sexual maturity: rationale for prophylactic (-)deprenyl (selegiline) medication. Life Sci. 56:1995;611-620.
    • (1995) Life Sci. , vol.56 , pp. 611-620
    • Knoll, J.1    Miklya, I.2
  • 20
    • 0000942494 scopus 로고
    • Phenylisopropylmethylpropynilamine (E-250), a monoamine oxidase inhibitor antagonizing effects of tyramine
    • Knoll J., Vizi E.S., Somogyi G. Phenylisopropylmethylpropynilamine (E-250), a monoamine oxidase inhibitor antagonizing effects of tyramine. Arzneim.-Forsch. 18:1968;109-112.
    • (1968) Arzneim.-Forsch. , vol.18 , pp. 109-112
    • Knoll, J.1    Vizi, E.S.2    Somogyi, G.3
  • 21
    • 0029670154 scopus 로고    scopus 로고
    • (-)Deprenyl and (-)1-phenyl-2-propylaminopentane, [(-)PPAP], act primarily as potent stimulants of action potential-transmitter release coupling in the catecholaminergic neurons
    • Knoll J., Miklya I., Knoll B., Markó R., Kelemen K. (-)Deprenyl and (-)1-phenyl-2-propylaminopentane, [(-)PPAP], act primarily as potent stimulants of action potential-transmitter release coupling in the catecholaminergic neurons. Life Sci. 58:1996;817-827.
    • (1996) Life Sci. , vol.58 , pp. 817-827
    • Knoll, J.1    Miklya, I.2    Knoll, B.3    Markó, R.4    Kelemen, K.5
  • 22
    • 0029670061 scopus 로고    scopus 로고
    • High performing rats are more sensitive toward catecholaminergic activity enhancer (CAE) compounds than their low performing peers
    • Knoll J., Knoll B., Miklya I. High performing rats are more sensitive toward catecholaminergic activity enhancer (CAE) compounds than their low performing peers. Life Sci. 58:1996;945-952.
    • (1996) Life Sci. , vol.58 , pp. 945-952
    • Knoll, J.1    Knoll, B.2    Miklya, I.3
  • 23
    • 0029903109 scopus 로고    scopus 로고
    • Phenylethylamine and tyramine are mixed-acting sympathomimetic amines in the brain
    • Knoll J., Miklya I., Knoll B., Markó R., Rácz D. Phenylethylamine and tyramine are mixed-acting sympathomimetic amines in the brain. Life Sci. 58:1996;2101-2114.
    • (1996) Life Sci. , vol.58 , pp. 2101-2114
    • Knoll, J.1    Miklya, I.2    Knoll, B.3    Markó, R.4    Rácz, D.5
  • 24
    • 0033432862 scopus 로고    scopus 로고
    • (-)1-(Benzofuran-2-yl)-2-propylaminopentane, [(-)BPAP], a selective enhancer of the impulse propagation mediated release of catecholamines and serotonin in the brain
    • Knoll J., Yoneda F., Knoll B., Ohde H., Miklya I. (-)1-(Benzofuran-2-yl)- 2-propylaminopentane, [(-)BPAP], a selective enhancer of the impulse propagation mediated release of catecholamines and serotonin in the brain. Br. J. Pharmacol. 128:1999;1723-1732.
    • (1999) Br. J. Pharmacol. , vol.128 , pp. 1723-1732
    • Knoll, J.1    Yoneda, F.2    Knoll, B.3    Ohde, H.4    Miklya, I.5
  • 25
    • 0037072615 scopus 로고    scopus 로고
    • 1-(Benzofuran-2-yl)-2-(3,3,3-trifluoropropyl)aminopentane HCl, 3-F-BPAP, antagonizes the enhancer effect of (-)-BPAP in the shuttle box and leaves the effect of (-)-deprenyl unchanged
    • Knoll J., Miklya I., Knoll B., Yasusa T., Shimazu S., Yoneda F. 1-(Benzofuran-2-yl)-2-(3,3,3-trifluoropropyl)aminopentane HCl, 3-F-BPAP, antagonizes the enhancer effect of (-)-BPAP in the shuttle box and leaves the effect of (-)-deprenyl unchanged. Life Sci. 71:2002;1975-1984.
    • (2002) Life Sci. , vol.71 , pp. 1975-1984
    • Knoll, J.1    Miklya, I.2    Knoll, B.3    Yasusa, T.4    Shimazu, S.5    Yoneda, F.6
  • 26
    • 0037144330 scopus 로고    scopus 로고
    • Stimulation of the catecholaminergic and serotoninergic neurons in the rat brain by R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane, (-)-BPAP
    • Knoll J., Miklya I., Knoll B. Stimulation of the catecholaminergic and serotoninergic neurons in the rat brain by R-(-)-1-(benzofuran-2-yl)-2- propylaminopentane, (-)-BPAP. Life Sci. 71:2002;2137-2144.
    • (2002) Life Sci. , vol.71 , pp. 2137-2144
    • Knoll, J.1    Miklya, I.2    Knoll, B.3
  • 27
    • 0030300165 scopus 로고    scopus 로고
    • The clinical potential of deprenyl in neurologic and psychiatric disorders
    • Kuhn W., Muller T. The clinical potential of deprenyl in neurologic and psychiatric disorders. J. Neural Transm., Suppl. 48:1996;85-93.
    • (1996) J. Neural Transm., Suppl. , vol.48 , pp. 85-93
    • Kuhn, W.1    Muller, T.2
  • 28
    • 0033385038 scopus 로고    scopus 로고
    • Does selegiline modify the progression of early Parkinson's disease? Results from a five-year study. The Norwegian-Danish Study Group
    • Larsen J.P., Boas J., Erdal J.E. Does selegiline modify the progression of early Parkinson's disease? Results from a five-year study. The Norwegian-Danish Study Group. Eur. J. Neurol. 6:1999;539-547.
    • (1999) Eur. J. Neurol. , vol.6 , pp. 539-547
    • Larsen, J.P.1    Boas, J.2    Erdal, J.E.3
  • 29
    • 0026286749 scopus 로고
    • Selegiline hydrochloride and cognition
    • Lees A.J. Selegiline hydrochloride and cognition. Acta Neurol. Scand., Suppl. 136:1991;91-94.
    • (1991) Acta Neurol. Scand., Suppl. , vol.136 , pp. 91-94
    • Lees, A.J.1
  • 30
    • 0019185890 scopus 로고
    • A selective monoamine oxidase-B inhibitor in endogenous depression
    • Mann J.J., Gershon S. A selective monoamine oxidase-B inhibitor in endogenous depression. Life Sci. 26:1980;877-882.
    • (1980) Life Sci. , vol.26 , pp. 877-882
    • Mann, J.J.1    Gershon, S.2
  • 31
    • 0029184021 scopus 로고
    • Depression in Parkinson's disease: A biochemical and organic viewpoint
    • Mayberg H.S., Solomon D.H. Depression in Parkinson's disease: a biochemical and organic viewpoint. Adv. Neurol. 65:1995;49.
    • (1995) Adv. Neurol. , vol.65 , pp. 49
    • Mayberg, H.S.1    Solomon, D.H.2
  • 33
    • 0020570351 scopus 로고
    • L-Deprenyl: A selective monoamine oxidase type B inhibitor, in the treatment of depression: A double-blind evaluation
    • Mendlewitz J., Youdim M.B.H. L-Deprenyl: a selective monoamine oxidase type B inhibitor, in the treatment of depression: a double-blind evaluation. Br. J. Psychiatry. 142:1983;508-511.
    • (1983) Br. J. Psychiatry , vol.142 , pp. 508-511
    • Mendlewitz, J.1    Youdim, M.B.H.2
  • 34
    • 0037427374 scopus 로고    scopus 로고
    • Analysis of the effect of (-)-BPAP, a selective enhancer of the impulse propagation mediated release of catecholamines and serotonin in the brain
    • Miklya I., Knoll J. Analysis of the effect of (-)-BPAP, a selective enhancer of the impulse propagation mediated release of catecholamines and serotonin in the brain. Life Sci. 72:2003;2915-2921.
    • (2003) Life Sci. , vol.72 , pp. 2915-2921
    • Miklya, I.1    Knoll, J.2
  • 35
    • 0037466256 scopus 로고    scopus 로고
    • A pharmacological analysis elucidating why, in contrast to (-)-deprenyl (Selegiline), α-tocopherol was ineffective in the DATATOP study
    • Miklya I., Knoll B., Knoll J. A pharmacological analysis elucidating why, in contrast to (-)-deprenyl (Selegiline), α-tocopherol was ineffective in the DATATOP study. Life Sci. 72:2003;2641-2648.
    • (2003) Life Sci. , vol.72 , pp. 2641-2648
    • Miklya, I.1    Knoll, B.2    Knoll, J.3
  • 36
    • 0037427373 scopus 로고    scopus 로고
    • An HPLC tracing of the enhancer regulation in selected discrete brain areas of food deprived rats
    • Miklya I., Knoll B., Knoll J. An HPLC tracing of the enhancer regulation in selected discrete brain areas of food deprived rats. Life Sci. 72:2003;2923-2930.
    • (2003) Life Sci. , vol.72 , pp. 2923-2930
    • Miklya, I.1    Knoll, B.2    Knoll, J.3
  • 37
    • 0035432429 scopus 로고    scopus 로고
    • Parkinson's disease
    • Miyoshi K. Parkinson's disease. Nippon Rinsho. 59:2001;1570-1573.
    • (2001) Nippon Rinsho , vol.59 , pp. 1570-1573
    • Miyoshi, K.1
  • 38
  • 40
    • 0037119165 scopus 로고    scopus 로고
    • The novel catecholaminergic and serotoninergic activity enhancer R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane up-regulates neurotrophic factor synthesis in mouse astrocytes
    • Ohta K., Ohta M., Mizuta I., Fujinami A., Shimazu S., Sato N., Yoneda F., Hayashi K., Kuno S. The novel catecholaminergic and serotoninergic activity enhancer R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane up-regulates neurotrophic factor synthesis in mouse astrocytes. Neurosci. Lett. 328:2002;205.
    • (2002) Neurosci. Lett. , vol.328 , pp. 205
    • Ohta, K.1    Ohta, M.2    Mizuta, I.3    Fujinami, A.4    Shimazu, S.5    Sato, N.6    Yoneda, F.7    Hayashi, K.8    Kuno, S.9
  • 41
    • 0035008575 scopus 로고    scopus 로고
    • Enantioselective synthesis and absolute configuration of (-)-1-(benzofuran-2-yl)-2-propylaminopentane, ((-)-BPAP), a highly potent and selective catecholaminergic activity enhancer
    • Oka T., Yasusa T., Ando T., Watanabe M., Yoneda F., Ishida T., Knoll J. Enantioselective synthesis and absolute configuration of (-)-1-(benzofuran-2-yl) -2-propylaminopentane, ((-)-BPAP), a highly potent and selective catecholaminergic activity enhancer. Bioorg. Med. Chem. 9:2001;1213-1219.
    • (2001) Bioorg. Med. Chem. , vol.9 , pp. 1213-1219
    • Oka, T.1    Yasusa, T.2    Ando, T.3    Watanabe, M.4    Yoneda, F.5    Ishida, T.6    Knoll, J.7
  • 42
    • 0024456653 scopus 로고
    • Effect of (-)deprenyl on the progression disability in early Parkinson's disease
    • Parkinson Study Group Effect of (-)deprenyl on the progression disability in early Parkinson's disease. N. Engl. J. Med. 321:1989;1364-1371.
    • (1989) N. Engl. J. Med. , vol.321 , pp. 1364-1371
  • 43
    • 0027530638 scopus 로고
    • Effect of tocopherol and (-)deprenyl on the progression of disability in early Parkinson's disease
    • Parkinson Study Group Effect of tocopherol and (-)deprenyl on the progression of disability in early Parkinson's disease. N. Engl. J. Med. 328:1993;176-183.
    • (1993) N. Engl. J. Med. , vol.328 , pp. 176-183
  • 46
    • 0030807313 scopus 로고    scopus 로고
    • Retrospective study of selegiline-antidepressant drug interactions and a review of the literature
    • Ritter J.L., Alexander B. Retrospective study of selegiline- antidepressant drug interactions and a review of the literature. Ann. Clin. Psychiatry. 9:1997;7-13.
    • (1997) Ann. Clin. Psychiatry , vol.9 , pp. 7-13
    • Ritter, J.L.1    Alexander, B.2
  • 47
    • 1842868704 scopus 로고
    • Catecholamines II
    • U. Trendelenburg, & N. Weiner. New York: Springer-Verlag
    • Saaverda J.M. Catecholamines II. Trendelenburg U., Weiner N. Handbook of Experimental Pharmacology. 1989;181-201 Springer-Verlag, New York.
    • (1989) Handbook of Experimental Pharmacology , pp. 181-201
    • Saaverda, J.M.1
  • 48
    • 0342983025 scopus 로고
    • Amine modulation of affective behavior
    • A.C. Sabelli. New York: Raven Press
    • Sabelli A.C., Giardina W.J. Amine modulation of affective behavior. Sabelli A.C. Chemical Modulation of Brain Function. 1973;225-259 Raven Press, New York.
    • (1973) Chemical Modulation of Brain Function , pp. 225-259
    • Sabelli, A.C.1    Giardina, W.J.2
  • 49
    • 0028952561 scopus 로고
    • Phenylethylamine modulation of affect: Therapeutic and diagnostic implications
    • Sabelli H.C., Javaid J.I. Phenylethylamine modulation of affect: therapeutic and diagnostic implications. J. Neuropsychiatry Clin. Neurosci. 7:1995;6-14.
    • (1995) J. Neuropsychiatry Clin. Neurosci. , vol.7 , pp. 6-14
    • Sabelli, H.C.1    Javaid, J.I.2
  • 50
    • 0022587586 scopus 로고
    • Clinical studies on the phenylethylamine hypothesis of affective disorder: Urine and blood phenylacetic acid and phenylalanine dietary supplements
    • Sabelli H.C., Fawcett J., Gusovsky F., Javaid J.I., Wynn P., Edwards J., Jeffriess H., Kravitz H.J. Clinical studies on the phenylethylamine hypothesis of affective disorder: urine and blood phenylacetic acid and phenylalanine dietary supplements. Clin. Psychiatry. 47:1986;66-70.
    • (1986) Clin. Psychiatry , vol.47 , pp. 66-70
    • Sabelli, H.C.1    Fawcett, J.2    Gusovsky, F.3    Javaid, J.I.4    Wynn, P.5    Edwards, J.6    Jeffriess, H.7    Kravitz, H.J.8
  • 54
    • 0035876074 scopus 로고    scopus 로고
    • (-)-1-(Benzofuran-2-yl)-2-propylaminopentane enhances locomotor activity in rats due to its ability to induce dopamine release
    • Shimazu S., Takahata K., Katsuki H., Tsunekawa H., Tanigawa A., Yoneda F., Knoll J., Akaike A. (-)-1-(Benzofuran-2-yl)-2-propylaminopentane enhances locomotor activity in rats due to its ability to induce dopamine release. Eur. J. Pharmacol. 421:2001;181-189.
    • (2001) Eur. J. Pharmacol. , vol.421 , pp. 181-189
    • Shimazu, S.1    Takahata, K.2    Katsuki, H.3    Tsunekawa, H.4    Tanigawa, A.5    Yoneda, F.6    Knoll, J.7    Akaike, A.8
  • 55
    • 0037422934 scopus 로고    scopus 로고
    • The L-DOPA-sparing effect of R-(-)-1-(benzofuran-2-yl)-2- propylaminopentane hydrochloride [(-)-BPAP] in reserpine-pretreated rats
    • Shimazu S., Tamashiro A., Yoneda F., Knoll J. The L-DOPA-sparing effect of R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane hydrochloride [(-)-BPAP] in reserpine-pretreated rats. Life Sci. 72:2003;1413-1419.
    • (2003) Life Sci. , vol.72 , pp. 1413-1419
    • Shimazu, S.1    Tamashiro, A.2    Yoneda, F.3    Knoll, J.4
  • 56
    • 0037414392 scopus 로고    scopus 로고
    • Enhancer substances: Selegiline and R-(-)-1-(benzofuran-2-yl)-2- propylaminopentane [(-)-BPAP] enhance the neurotrophic factor synthesis on cultured mouse astrocytes
    • Shimazu S., Tanigawa A., Sato N., Yoneda F., Hayashi K., Knoll J. Enhancer substances: selegiline and R-(-)-1-(benzofuran-2-yl)-2- propylaminopentane [(-)-BPAP] enhance the neurotrophic factor synthesis on cultured mouse astrocytes. Life Sci. 72:2003;2785-2792.
    • (2003) Life Sci. , vol.72 , pp. 2785-2792
    • Shimazu, S.1    Tanigawa, A.2    Sato, N.3    Yoneda, F.4    Hayashi, K.5    Knoll, J.6
  • 57
    • 0024343466 scopus 로고
    • The effect of (-)deprenyl (selegiline) on the natural history of Parkinson's disease
    • Tetrud J.W., Langston J.W. The effect of (-)deprenyl (selegiline) on the natural history of Parkinson's disease. Science. 245:1989;519-522.
    • (1989) Science , vol.245 , pp. 519-522
    • Tetrud, J.W.1    Langston, J.W.2
  • 58
    • 0031983225 scopus 로고    scopus 로고
    • Depression in Parkinson's disease. Pharmacological characteristics and treatment
    • Tom T., Cummings J.L. Depression in Parkinson's disease. Pharmacological characteristics and treatment. Drugs Aging. 12:1998;55-74.
    • (1998) Drugs Aging , vol.12 , pp. 55-74
    • Tom, T.1    Cummings, J.L.2
  • 59
    • 0007648324 scopus 로고
    • The effect of L-E-250 (-L-phenyl-isopropylmethyl-propinyl-amine HCl) in depression
    • G. Leszkovszky. Budapest, Hungary: Publishing House of the Hungarian Academy of Sciences
    • Tringer L., Haits G., Varga E. The effect of L-E-250 (-L-phenyl- isopropylmethyl-propinyl-amine HCl) in depression. Leszkovszky G. V. Conferentia Hungarica pro Therapia et Investigatione in Pharmacologia. 1971;111-114 Publishing House of the Hungarian Academy of Sciences, Budapest, Hungary.
    • (1971) V. Conferentia Hungarica Pro Therapia et Investigatione in Pharmacologia , pp. 111-114
    • Tringer, L.1    Haits, G.2    Varga, E.3
  • 61
    • 0024533976 scopus 로고
    • Tryptamine receptors: Neurochemical and electrophysiological evidence for postsynaptic and functional binding sites
    • van Nguyen T., Paterson I.A., Juorio A.V., Greenshaw A.J., Boulton A.A. Tryptamine receptors: neurochemical and electrophysiological evidence for postsynaptic and functional binding sites. Brain Res. 476:1989;85-93.
    • (1989) Brain Res. , vol.476 , pp. 85-93
    • Van Nguyen, T.1    Paterson, I.A.2    Juorio, A.V.3    Greenshaw, A.J.4    Boulton, A.A.5
  • 62
    • 0007644972 scopus 로고
    • Vorl ä ufiger Bericht über die Wirkung des Prparats E-250 (phenyl-isopropyl-methyl-propinylamine-chlorhydrat)
    • B. Dumbovich. Budapest, Hungary: Publishing House of the Hungarian Academy of Sciences
    • Varga E. Vorl ä ufiger Bericht über die Wirkung des Prparats E-250 (phenyl-isopropyl-methyl-propinylamine-chlorhydrat). Dumbovich B. III Conferentia Hungarica pro Therapia et Investigatione in Pharmacologia. 1965;197-201 Publishing House of the Hungarian Academy of Sciences, Budapest, Hungary.
    • (1965) III Conferentia Hungarica Pro Therapia et Investigatione in Pharmacologia , pp. 197-201
    • Varga, E.1
  • 63
    • 0014189254 scopus 로고
    • Clinical trial of a new type of promptly acting psychoenergetic agent (phenyl-isopropylmethyl-propinylamine HCl, E-250)
    • Varga E., Tringer L. Clinical trial of a new type of promptly acting psychoenergetic agent (phenyl-isopropylmethyl-propinylamine HCl, E-250). Acta Med. Acad. Sci. Hung. 23:1967;289-295.
    • (1967) Acta Med. Acad. Sci. Hung. , vol.23 , pp. 289-295
    • Varga, E.1    Tringer, L.2
  • 64
    • 0029806473 scopus 로고    scopus 로고
    • Tyramine content of previously restricted foods in monoamine oxidase inhibitor diets
    • Walker S.E., Shulman K.I., Tailor S.A., Gardner D. Tyramine content of previously restricted foods in monoamine oxidase inhibitor diets. J. Clin. Psychopharmacol. 16:1996;383-388.
    • (1996) J. Clin. Psychopharmacol. , vol.16 , pp. 383-388
    • Walker, S.E.1    Shulman, K.I.2    Tailor, S.A.3    Gardner, D.4
  • 65
    • 0035007209 scopus 로고    scopus 로고
    • Structure-activity studies leading to (-)1-(benzofuran-2-yl)-2- propylaminopentane, [(-)BPAP], a highly potent, selective enhancer of the impulse propagation mediated release of catecholamines and serotonin in the brain
    • Yoneda F., Moto T., Sakae M., Ohde H., Knoll B., Miklya I., Knoll J. Structure-activity studies leading to (-)1-(benzofuran-2-yl)-2- propylaminopentane, [(-)BPAP], a highly potent, selective enhancer of the impulse propagation mediated release of catecholamines and serotonin in the brain. Bioorg. Med. Chem. 9:2001;1197-1212.
    • (2001) Bioorg. Med. Chem. , vol.9 , pp. 1197-1212
    • Yoneda, F.1    Moto, T.2    Sakae, M.3    Ohde, H.4    Knoll, B.5    Miklya, I.6    Knoll, J.7
  • 66
    • 0019292405 scopus 로고
    • Monoamine oxidase inhibitors as anti-depressant drugs and as adjunct to L-dopa therapy of Parkinson's disease
    • Youdim M.B. Monoamine oxidase inhibitors as anti-depressant drugs and as adjunct to L-dopa therapy of Parkinson's disease. J. Neural Transm. Suppl. 16:1980;157-161.
    • (1980) J. Neural Transm. , vol.16 , pp. 157-161
    • Youdim, M.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.