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Volumn 9, Issue 8, 2004, Pages 366-374

Autism: A target of pharmacotherapies?

Author keywords

Alzheimer's disease; Autism spectrum disease; Biochemistry; Brain disorders; Candidate loci; Disease genes; Disease mechanisms; Drug Discovery; Molecular Medicine; Neurobiology; Pharmaceutical Science; Pharmacotherapies

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; BUSPIRONE; CLOZAPINE; DOPAMINE 2 RECEPTOR BLOCKING AGENT; FLUOXETINE; FLUPHENAZINE; HALOPERIDOL; HISTAMINE H1 RECEPTOR ANTAGONIST; NALTREXONE; OLANZAPINE; OPIATE ANTAGONIST; PIMOZIDE; RISPERIDONE; SECRETIN; SEROTONIN 1A AGONIST; SEROTONIN 2A ANTAGONIST; SEROTONIN ANTAGONIST; SEROTONIN UPTAKE INHIBITOR;

EID: 1842635431     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(04)03039-9     Document Type: Review
Times cited : (24)

References (95)
  • 1
    • 0037030360 scopus 로고    scopus 로고
    • The secrets of autism
    • Nash M.J. The secrets of autism. Time. 159:2002;46-56.
    • (2002) Time , vol.159 , pp. 46-56
    • Nash, M.J.1
  • 2
    • 0035812741 scopus 로고    scopus 로고
    • New hints into the biological basis of autism
    • Stokstad E. New hints into the biological basis of autism. Science. 294:2001;34-37.
    • (2001) Science , vol.294 , pp. 34-37
    • Stokstad, E.1
  • 4
  • 6
    • 0024430952 scopus 로고
    • Autism diagnostic interview: A semi-structured interview for parents and caregivers of autistic persons
    • LeCouter A., et al. Autism diagnostic interview: a semi-structured interview for parents and caregivers of autistic persons. J. Autism Dev. Disord. 19:1989;363-387.
    • (1989) J. Autism Dev. Disord. , vol.19 , pp. 363-387
    • Lecouter, A.1
  • 7
    • 0027997172 scopus 로고
    • Autism diagnostic interview- revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders
    • Lord C., et al. Autism diagnostic interview- revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. J. Autism Dev. Disord. 24:1994;659-685.
    • (1994) J. Autism Dev. Disord. , vol.24 , pp. 659-685
    • Lord, C.1
  • 8
    • 0029093668 scopus 로고
    • Pre-linguistic autism diagnostic observation schedule (PL-ADOS)
    • DiLavore P., et al. Pre-linguistic autism diagnostic observation schedule (PL-ADOS). J. Autism Dev. Disord. 25:1995;355-379.
    • (1995) J. Autism Dev. Disord. , vol.25 , pp. 355-379
    • Dilavore, P.1
  • 9
    • 0033802632 scopus 로고    scopus 로고
    • The autism diagnostic observation schedule-generic: A standard measure of social and communication deficits associated with the spectrum of autism
    • Lord C., et al. The autism diagnostic observation schedule-generic: a standard measure of social and communication deficits associated with the spectrum of autism. J. Autism Dev. Disord. 30:2000;205-223.
    • (2000) J. Autism Dev. Disord. , vol.30 , pp. 205-223
    • Lord, C.1
  • 10
    • 0000984981 scopus 로고
    • Autistic disturbances of affective contact
    • Kanner L. Autistic disturbances of affective contact. Nervous Child. 2:1943;217-250.
    • (1943) Nervous Child , vol.2 , pp. 217-250
    • Kanner, L.1
  • 11
    • 0002148785 scopus 로고    scopus 로고
    • Syndromes of autism and atypical development
    • (Cohen D.J. and Volkmar F.R. eds) John Wiley, New York
    • Wing, L. (1997) Syndromes of autism and atypical development. In Handbook of Autism and Pervasive Developmental Disorders (2nd edn), (Cohen D.J. and Volkmar F.R. eds) pp 148-170, John Wiley, New York
    • (1997) Handbook of Autism and Pervasive Developmental Disorders (2nd Edn) , pp. 148-170
    • Wing, L.1
  • 12
    • 0019522216 scopus 로고
    • Asperger's syndrome: A clinical account
    • Wing L. Asperger's syndrome: a clinical account. Psychol. Med. 11:1981;115-129.
    • (1981) Psychol. Med. , vol.11 , pp. 115-129
    • Wing, L.1
  • 14
    • 0033837083 scopus 로고    scopus 로고
    • Practice parameter: Screening and diagnosis of autism
    • Filipek P.A., et al. Practice parameter: screening and diagnosis of autism. Neurology. 55:2000;468-479.
    • (2000) Neurology , vol.55 , pp. 468-479
    • Filipek, P.A.1
  • 16
    • 0036674520 scopus 로고    scopus 로고
    • The autistic spectrum disorders
    • Rapin I. The autistic spectrum disorders. N. Engl. J. Med. 347:2002;302-303.
    • (2002) N. Engl. J. Med. , vol.347 , pp. 302-303
    • Rapin, I.1
  • 17
    • 0035291450 scopus 로고    scopus 로고
    • Autism and the school nurse
    • Cade M., Tidwell S. Autism and the school nurse. J. Sch. Health. 71:2001;96-100.
    • (2001) J. Sch. Health , vol.71 , pp. 96-100
    • Cade, M.1    Tidwell, S.2
  • 18
    • 0037218690 scopus 로고    scopus 로고
    • Prevalence of autism in a US metropolitan area
    • Yeargin-Allsopp M., et al. Prevalence of autism in a US metropolitan area. J.A.M.A. 289:2003;49-55.
    • (2003) J.A.M.A. , vol.289 , pp. 49-55
    • Yeargin-Allsopp, M.1
  • 20
    • 0034850160 scopus 로고    scopus 로고
    • Infectious and immune factors in the pathogenesis of neurodevelopmental disorders: Epidemiology, hypotheses, and animal models
    • Hornig M., Lipkin W.I. Infectious and immune factors in the pathogenesis of neurodevelopmental disorders: epidemiology, hypotheses, and animal models. Ment. Retard. Dev. Disabil. Res. Rev. 7:2001;200-221.
    • (2001) Ment. Retard. Dev. Disabil. Res. Rev. , vol.7 , pp. 200-221
    • Hornig, M.1    Lipkin, W.I.2
  • 21
    • 0036195694 scopus 로고    scopus 로고
    • Genetic and immunologic considerations in autism
    • Korvatska E., et al. Genetic and immunologic considerations in autism. Neurobiol. Dis. 9:2002;107-125.
    • (2002) Neurobiol. Dis. , vol.9 , pp. 107-125
    • Korvatska, E.1
  • 22
    • 0036163344 scopus 로고    scopus 로고
    • Use of secretin in the treatment of childhood autism
    • Kaminska B., et al. Use of secretin in the treatment of childhood autism. Med. Sci. Moni. 8:2002;RA22-RA26.
    • (2002) Med. Sci. Moni. , vol.8 , pp. 22-RA26
    • Kaminska, B.1
  • 23
    • 0035693008 scopus 로고    scopus 로고
    • Reports on dietary intervention in autistic disorders
    • Knivsber A.M., et al. Reports on dietary intervention in autistic disorders. Nutr. Neurosci. 4:2001;25-37.
    • (2001) Nutr. Neurosci. , vol.4 , pp. 25-37
    • Knivsber, A.M.1
  • 24
    • 0032189987 scopus 로고    scopus 로고
    • Serological association of measles virus and human herpesvirus-6 with brain autoantibodies in autism
    • Singh V.K., et al. Serological association of measles virus and human herpesvirus-6 with brain autoantibodies in autism. Clin. Immunol. Immunopathol. 89:1998;105-108.
    • (1998) Clin. Immunol. Immunopathol. , vol.89 , pp. 105-108
    • Singh, V.K.1
  • 25
    • 0035034979 scopus 로고    scopus 로고
    • Intra-monocyte pathogens delineate autism subgroups
    • Binstock T. Intra-monocyte pathogens delineate autism subgroups. Med. Hypotheses. 56:2001;523-531.
    • (2001) Med. Hypotheses , vol.56 , pp. 523-531
    • Binstock, T.1
  • 26
    • 0035052091 scopus 로고    scopus 로고
    • Measles virus persistence in specimens of inflammatory bowel disease and autism cases
    • Afzal M.A., et al. Measles virus persistence in specimens of inflammatory bowel disease and autism cases. Dig. Dis. Sci. 46:2001;658-660.
    • (2001) Dig. Dis. Sci. , vol.46 , pp. 658-660
    • Afzal, M.A.1
  • 27
    • 0028350617 scopus 로고
    • Autism in thalidomide embryopathy: A population study
    • Strömland K., et al. Autism in thalidomide embryopathy: a population study. Dev. Med. Child Neurol. 36:1994;351-356.
    • (1994) Dev. Med. Child Neurol. , vol.36 , pp. 351-356
    • Strömland, K.1
  • 28
    • 0031019120 scopus 로고    scopus 로고
    • Pitocin induction and autism
    • Fein D., et al. Pitocin induction and autism. Am. J. Psychiat. 154:1997;438-439.
    • (1997) Am. J. Psychiat. , vol.154 , pp. 438-439
    • Fein, D.1
  • 29
    • 0030983932 scopus 로고    scopus 로고
    • Neurochemical effects of PCBs - An overview
    • Tilson H.A. Neurochemical effects of PCBs - an overview. Neurotoxicol. 18:1997;727-744.
    • (1997) Neurotoxicol. , vol.18 , pp. 727-744
    • Tilson, H.A.1
  • 33
    • 0242291090 scopus 로고    scopus 로고
    • Model of autism: Increased ratio of excitation/inhibition in key neural systems
    • Rubenstein J.L.R., Merzenich M.M. Model of autism: increased ratio of excitation/inhibition in key neural systems. Genes Brain Behav. 2:2003;255-267.
    • (2003) Genes Brain Behav. , vol.2 , pp. 255-267
    • Rubenstein, J.L.R.1    Merzenich, M.M.2
  • 34
    • 0000211820 scopus 로고    scopus 로고
    • Does Asperger syndrome aggregate in families?
    • A. et al. Klin. New York: Guilford Press
    • Folstein S., Santangelo S. Does Asperger syndrome aggregate in families? Klin A., et al. Asperger Syndrome. 2000;159-171 Guilford Press, New York.
    • (2000) Asperger Syndrome , pp. 159-171
    • Folstein, S.1    Santangelo, S.2
  • 35
    • 0028906338 scopus 로고
    • Autism as a strongly genetic disorder: Evidence from a British twin study
    • Bailey A., et al. Autism as a strongly genetic disorder: evidence from a British twin study. Psychol. Med. 25:1995;63-77.
    • (1995) Psychol. Med. , vol.25 , pp. 63-77
    • Bailey, A.1
  • 36
    • 0032892309 scopus 로고    scopus 로고
    • Genetics and child psychiatry: II empirical research findings
    • Rutter M., et al. Genetics and child psychiatry: II empirical research findings. J. Child Psychol. Psychiatry. 40:1999;19-55.
    • (1999) J. Child Psychol. Psychiatry , vol.40 , pp. 19-55
    • Rutter, M.1
  • 37
    • 0042884430 scopus 로고    scopus 로고
    • Autism: A large unmet medical need and a complex research problem
    • Gerlai J., Gerlai R. Autism: a large unmet medical need and a complex research problem. Physiol. Behav. 79:2003;461-470.
    • (2003) Physiol. Behav. , vol.79 , pp. 461-470
    • Gerlai, J.1    Gerlai, R.2
  • 38
    • 0033865944 scopus 로고    scopus 로고
    • The SPCH1 region on human 7q31: Genomic characterization of the critical interval and localization of translocations associated with speech and language disorder
    • Lai C.S.L., et al. The SPCH1 region on human 7q31: genomic characterization of the critical interval and localization of translocations associated with speech and language disorder. Am. J. Hum. Genet. 67:2000;357-368.
    • (2000) Am. J. Hum. Genet. , vol.67 , pp. 357-368
    • Lai, C.S.L.1
  • 39
    • 0031940694 scopus 로고    scopus 로고
    • Localisation of a gene implicated in severe speech and language disorder
    • Fisher S.E., et al. Localisation of a gene implicated in severe speech and language disorder. Nat. Genet. 18:1998;168-170.
    • (1998) Nat. Genet. , vol.18 , pp. 168-170
    • Fisher, S.E.1
  • 41
    • 85047695651 scopus 로고    scopus 로고
    • Serotonin transporter gene polymorphisms and hyperserotonemia in autistic disorder
    • Betancur C., et al. Serotonin transporter gene polymorphisms and hyperserotonemia in autistic disorder. Mol. Psychiatry. 7:2002;67-71.
    • (2002) Mol. Psychiatry , vol.7 , pp. 67-71
    • Betancur, C.1
  • 42
    • 0029803880 scopus 로고    scopus 로고
    • A double-blind, placebo controlled study of fluvoxamine in adults with autistic disorder
    • McDougle C.J., et al. A double-blind, placebo controlled study of fluvoxamine in adults with autistic disorder. Arch. Gen. Psychiatry. 53:1996;1001-1008.
    • (1996) Arch. Gen. Psychiatry , vol.53 , pp. 1001-1008
    • McDougle, C.J.1
  • 43
    • 0035827826 scopus 로고    scopus 로고
    • Evidence supporting WNT2 as an autism susceptibility gene
    • Wassink T.H., et al. Evidence supporting WNT2 as an autism susceptibility gene. Am. J. Med. Genet. 105:2001;406-413.
    • (2001) Am. J. Med. Genet. , vol.105 , pp. 406-413
    • Wassink, T.H.1
  • 44
    • 0035115588 scopus 로고    scopus 로고
    • Reelin mutations in mouse and man: From reeler mouse to schizophrenia, mood disorders, autism and lissencephaly
    • Fatemi S.H. Reelin mutations in mouse and man: from reeler mouse to schizophrenia, mood disorders, autism and lissencephaly. Mol. Psychiatry. 6:2001;129-133.
    • (2001) Mol. Psychiatry , vol.6 , pp. 129-133
    • Fatemi, S.H.1
  • 45
    • 0033817428 scopus 로고    scopus 로고
    • Molecular genetic advances in tuberous sclerosis
    • Cheadle J.P., et al. Molecular genetic advances in tuberous sclerosis. Hum. Genet. 107:2000;97-114.
    • (2000) Hum. Genet. , vol.107 , pp. 97-114
    • Cheadle, J.P.1
  • 46
    • 0033544919 scopus 로고    scopus 로고
    • Characterization of the cytosolic tuberin-harmatin complex. Tuberin is a cytosolic chaperone for hamartin
    • Nellist M., et al. Characterization of the cytosolic tuberin-harmatin complex. Tuberin is a cytosolic chaperone for hamartin. J. Biol. Chem. 274:1999;35647-35652.
    • (1999) J. Biol. Chem. , vol.274 , pp. 35647-35652
    • Nellist, M.1
  • 48
    • 0032461803 scopus 로고    scopus 로고
    • Autism: The point of view from fragile X studies
    • Feinstein C., Reiss A.L. Autism: the point of view from fragile X studies. J. Autism Dev. Disord. 28:1998;393-405.
    • (1998) J. Autism Dev. Disord. , vol.28 , pp. 393-405
    • Feinstein, C.1    Reiss, A.L.2
  • 49
    • 0037656313 scopus 로고    scopus 로고
    • Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism
    • Jamain S., et al. Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism. Nat. Genet. 34:2003;27-29.
    • (2003) Nat. Genet. , vol.34 , pp. 27-29
    • Jamain, S.1
  • 50
    • 0036837658 scopus 로고    scopus 로고
    • Variable expression of mental retardation, autism, seizures, and dystonic hand movements in two families with an identical ARX genemutation
    • Turner G., et al. Variable expression of mental retardation, autism, seizures, and dystonic hand movements in two families with an identical ARX genemutation. Am. J. Med. Genet. 112:2002;405-411.
    • (2002) Am. J. Med. Genet. , vol.112 , pp. 405-411
    • Turner, G.1
  • 51
    • 0033358742 scopus 로고    scopus 로고
    • Genetics of Angelman syndrome
    • Jiang Y., et al. Genetics of Angelman syndrome. Am. J. Hum. Genet. 65:1999;1-6.
    • (1999) Am. J. Hum. Genet. , vol.65 , pp. 1-6
    • Jiang, Y.1
  • 52
    • 0037371673 scopus 로고    scopus 로고
    • Fine mapping of autistic disorder to chromosome 15q11-q13 by use of phenotypic subtypes
    • Shao Y., et al. Fine mapping of autistic disorder to chromosome 15q11-q13 by use of phenotypic subtypes. Am. J. Hum. Genet. 72:2003;539-548.
    • (2003) Am. J. Hum. Genet. , vol.72 , pp. 539-548
    • Shao, Y.1
  • 53
    • 0035755097 scopus 로고    scopus 로고
    • Density amd distribution of hippocampal neurotransmitter receptors in autism: An autoradiographic study
    • Blatt G.J., et al. Density amd distribution of hippocampal neurotransmitter receptors in autism: an autoradiographic study. J. Autism Dev. Disord. 31:2001;537-544.
    • (2001) J. Autism Dev. Disord. , vol.31 , pp. 537-544
    • Blatt, G.J.1
  • 54
    • 0030296413 scopus 로고    scopus 로고
    • Serotonin and autism: Biochemical and molecular biology features
    • Hérault J., et al. Serotonin and autism: biochemical and molecular biology features. Psychiatry Res. 65:1996;33-43.
    • (1996) Psychiatry Res. , vol.65 , pp. 33-43
    • Hérault, J.1
  • 55
    • 0034714506 scopus 로고    scopus 로고
    • Is there a basis for novel pharmacotherapy of autism?
    • Hunsinger D.M., et al. Is there a basis for novel pharmacotherapy of autism? Life Sci. 67:2000;1667-1682.
    • (2000) Life Sci. , vol.67 , pp. 1667-1682
    • Hunsinger, D.M.1
  • 56
    • 0031880046 scopus 로고    scopus 로고
    • Hypothesis: Is infantile autism a hypoglutamatergic disorder? Relevance of glutamate - Serotonin interactions for pharmacotherapy
    • Carlsson M.L. Hypothesis: is infantile autism a hypoglutamatergic disorder? Relevance of glutamate - serotonin interactions for pharmacotherapy. J. Neural Transm. 105:1998;525-535.
    • (1998) J. Neural Transm. , vol.105 , pp. 525-535
    • Carlsson, M.L.1
  • 57
    • 85047695028 scopus 로고    scopus 로고
    • Linkage and association between glutamate receptor 6 and autism
    • Jamain S., et al. Linkage and association between glutamate receptor 6 and autism. Mol. Psychiatry. 7:2002;302-310.
    • (2002) Mol. Psychiatry , vol.7 , pp. 302-310
    • Jamain, S.1
  • 58
    • 0026849420 scopus 로고
    • A mutation in adenylosuccinate lyase associated with mental retardation and autistic features
    • Stone R.L., et al. A mutation in adenylosuccinate lyase associated with mental retardation and autistic features. Nat. Genet. 1:1992;59-63.
    • (1992) Nat. Genet. , vol.1 , pp. 59-63
    • Stone, R.L.1
  • 59
    • 85047685961 scopus 로고    scopus 로고
    • Autism: Evidence of association with adenosine deaminase genetic polymorphism
    • Bottini N., et al. Autism: evidence of association with adenosine deaminase genetic polymorphism. Neurogenetics. 2:2001;111-113.
    • (2001) Neurogenetics , vol.2 , pp. 111-113
    • Bottini, N.1
  • 60
    • 0034606332 scopus 로고    scopus 로고
    • Adenosine deaminase alleles and autistic disorder: Case-control and family-based association studies
    • Persico A.M., et al. Adenosine deaminase alleles and autistic disorder: case-control and family-based association studies. Am. J. Med. Genet. 96:2000;784-790.
    • (2000) Am. J. Med. Genet. , vol.96 , pp. 784-790
    • Persico, A.M.1
  • 61
    • 0035886219 scopus 로고    scopus 로고
    • Oxytocin and autistic disorder: Alterations in peptide forms
    • Green L., et al. Oxytocin and autistic disorder: alterations in peptide forms. Biol. Psychiatry. 50:2001;609-613.
    • (2001) Biol. Psychiatry , vol.50 , pp. 609-613
    • Green, L.1
  • 62
    • 0033556679 scopus 로고    scopus 로고
    • Oxytocin, vasopressin, and autism: Is there a connection?
    • Insel T.R., et al. Oxytocin, vasopressin, and autism: is there a connection? Biol. Psychiatry. 45:1999;145-157.
    • (1999) Biol. Psychiatry , vol.45 , pp. 145-157
    • Insel, T.R.1
  • 63
    • 0032519523 scopus 로고    scopus 로고
    • Plasma oxytocin levels in autistic children
    • Modahl C., et al. Plasma oxytocin levels in autistic children. Biol. Psychiatry. 43:1998;270-277.
    • (1998) Biol. Psychiatry , vol.43 , pp. 270-277
    • Modahl, C.1
  • 64
    • 0035021249 scopus 로고    scopus 로고
    • Neuropeptides and neurotrophins in neonatal blood of children with autism or mental retardation
    • Nelson K.B., et al. Neuropeptides and neurotrophins in neonatal blood of children with autism or mental retardation. Ann. Neurol. 49:2001;597-606.
    • (2001) Ann. Neurol. , vol.49 , pp. 597-606
    • Nelson, K.B.1
  • 65
    • 0035752968 scopus 로고    scopus 로고
    • The abnormal regulation of gene expression in autistic brain tissue
    • Purcell A.E., et al. The abnormal regulation of gene expression in autistic brain tissue. J. Autism Dev. Disord. 31:2001;545-549.
    • (2001) J. Autism Dev. Disord. , vol.31 , pp. 545-549
    • Purcell, A.E.1
  • 66
    • 0036682267 scopus 로고    scopus 로고
    • Risperidone in children with autism and serious behavioral problems
    • McCracken J.T., et al. Risperidone in children with autism and serious behavioral problems. N. Engl. J. Med. 347:2002;314-321.
    • (2002) N. Engl. J. Med. , vol.347 , pp. 314-321
    • McCracken, J.T.1
  • 67
    • 0033917855 scopus 로고    scopus 로고
    • The pharmacotherapy of target symptoms associated with autistic disorder and other pervasive developmental disorders
    • Posey D.J., McDougle C.J. The pharmacotherapy of target symptoms associated with autistic disorder and other pervasive developmental disorders. Harv. Rev. Psychiatry. 8:2000;45-63.
    • (2000) Harv. Rev. Psychiatry , vol.8 , pp. 45-63
    • Posey, D.J.1    McDougle, C.J.2
  • 68
    • 0035430886 scopus 로고    scopus 로고
    • A review of subtyping in autism and proposed dimensional classification model
    • Beglinger L.J., Smith T.H. A review of subtyping in autism and proposed dimensional classification model. J. Autism Dev. Disord. 31:2001;411-422.
    • (2001) J. Autism Dev. Disord. , vol.31 , pp. 411-422
    • Beglinger, L.J.1    Smith, T.H.2
  • 69
    • 0035754786 scopus 로고    scopus 로고
    • Proteomic approach for the elucidation of biological defects in autism
    • Junaid M.A., Pullarkat R.K. Proteomic approach for the elucidation of biological defects in autism. J. Autism Dev. Disord. 31:2001;557-560.
    • (2001) J. Autism Dev. Disord. , vol.31 , pp. 557-560
    • Junaid, M.A.1    Pullarkat, R.K.2
  • 70
    • 0242322727 scopus 로고    scopus 로고
    • Bioinformatic analysis of autism positional candidate genes using biological databases and computational gene network prediction
    • Yonan A.L., et al. Bioinformatic analysis of autism positional candidate genes using biological databases and computational gene network prediction. Genes Brain Behav. 2:2003;303-320.
    • (2003) Genes Brain Behav. , vol.2 , pp. 303-320
    • Yonan, A.L.1
  • 71
    • 4644373224 scopus 로고    scopus 로고
    • Sociability and preference for social novelty in five inbred strains: An approach to assess autistic-like behavior in mice
    • (in press)
    • Moy, S.S. et al. Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice, Genes Brain Behav. (in press)
    • Genes Brain Behav.
    • Moy, S.S.1
  • 72
    • 0033082436 scopus 로고    scopus 로고
    • Analysing hippocampal function in transgenic mice: An ethological perspective
    • Gerlai R. and Clayton, N.S. (1999) Analysing hippocampal function in transgenic mice: an ethological perspective, Trends Neurosci. 22, 47-51
    • (1999) Trends Neurosci. , vol.22 , pp. 47-51
    • Gerlai, R.1    Clayton, N.S.2
  • 73
    • 0036148515 scopus 로고    scopus 로고
    • Molecular genetics and animal models in autistic disorder
    • Andres C. Molecular genetics and animal models in autistic disorder. Brain Res. Bull. 57:2002;109-119.
    • (2002) Brain Res. Bull. , vol.57 , pp. 109-119
    • Andres, C.1
  • 74
    • 85047700330 scopus 로고    scopus 로고
    • Association between a GABRB3 polymorphism and autism
    • Buxbaum J.D., et al. Association between a GABRB3 polymorphism and autism. Mol. Psychiatry. 7:2002;311-316.
    • (2002) Mol. Psychiatry , vol.7 , pp. 311-316
    • Buxbaum, J.D.1
  • 75
    • 0036553050 scopus 로고    scopus 로고
    • The social deficits of the oxytocin knockout mouse
    • Winslow J.T., Insel T.R. The social deficits of the oxytocin knockout mouse. Neuropeptides. 36:2002;221-229.
    • (2002) Neuropeptides , vol.36 , pp. 221-229
    • Winslow, J.T.1    Insel, T.R.2
  • 76
    • 0029169674 scopus 로고
    • Association study with two markers of a human homeogene in infantile autism
    • Petit E., et al. Association study with two markers of a human homeogene in infantile autism. J. Med. Genet. 32:1995;269-274.
    • (1995) J. Med. Genet. , vol.32 , pp. 269-274
    • Petit, E.1
  • 77
    • 0028325992 scopus 로고
    • Abnormal embryonic cerebellar development and patterning of postnatal foliation in two mouse Engrailed-2 mutants
    • Millen K.J., et al. Abnormal embryonic cerebellar development and patterning of postnatal foliation in two mouse Engrailed-2 mutants. Development. 120:1994;695-706.
    • (1994) Development , vol.120 , pp. 695-706
    • Millen, K.J.1
  • 78
    • 0025884460 scopus 로고
    • Subtle cerebellar phenotype in mice homozygous for a targeted deletion of the En-2 homeobox
    • Joyner A.L., et al. Subtle cerebellar phenotype in mice homozygous for a targeted deletion of the En-2 homeobox. Science. 251:1991;1239-1243.
    • (1991) Science , vol.251 , pp. 1239-1243
    • Joyner, A.L.1
  • 79
    • 0030929668 scopus 로고    scopus 로고
    • Transgenic rescue from embryonic lethality and renal carcinogenesis in the Eker rat model by introduction of a wild-tupe Tsc2 gene
    • Kobayashi T., et al. Transgenic rescue from embryonic lethality and renal carcinogenesis in the Eker rat model by introduction of a wild-tupe Tsc2 gene. Proc. Natl. Acad. Sci. U. S. A. 94:1997;3990-3993.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 3990-3993
    • Kobayashi, T.1
  • 80
    • 0034717341 scopus 로고    scopus 로고
    • Enhanced cardcardiomyocyte DNA synthesis during myocardial hypertrophy in mice expressing a modified Tsc2 transgene
    • Pasumarthi K.B., et al. Enhanced cardcardiomyocyte DNA synthesis during myocardial hypertrophy in mice expressing a modified Tsc2 transgene. Circ. Res. 86:2000;1069-1077.
    • (2000) Circ. Res. , vol.86 , pp. 1069-1077
    • Pasumarthi, K.B.1
  • 81
    • 0031014044 scopus 로고    scopus 로고
    • Mildly impaired water maze performance in male Fmr1 knockout mice
    • D'Hooge R., et al. Mildly impaired water maze performance in male Fmr1 knockout mice. Neuroscience. 76:1997;367-376.
    • (1997) Neuroscience , vol.76 , pp. 367-376
    • D'Hooge, R.1
  • 82
    • 0030003953 scopus 로고    scopus 로고
    • Transgenic mouse model for the fragile X syndrome
    • Kooy R.F., et al. Transgenic mouse model for the fragile X syndrome. Am. J. Med. Genet. 64:1996;241-245.
    • (1996) Am. J. Med. Genet. , vol.64 , pp. 241-245
    • Kooy, R.F.1
  • 83
    • 0031410204 scopus 로고    scopus 로고
    • Animal model for fragile X syndrome
    • Oostra B.A., Hoogeeveen A.T. Animal model for fragile X syndrome. Ann. Med. 29:1997;563-567.
    • (1997) Ann. Med. , vol.29 , pp. 563-567
    • Oostra, B.A.1    Hoogeeveen, A.T.2
  • 84
    • 0034194228 scopus 로고    scopus 로고
    • (Over)correction of FMR1 deficiency with YAC transgenics: Behavioral and physical features
    • Peier A.M., et al. (Over)correction of FMR1 deficiency with YAC transgenics: behavioral and physical features. Hum. Mol. Genet. 9:2000;1145-1159.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 1145-1159
    • Peier, A.M.1
  • 85
    • 9044254932 scopus 로고    scopus 로고
    • Impaired motor learning performance in cerebellar En-2 mutant mice
    • Gerlai R., et al. Impaired motor learning performance in cerebellar En-2 mutant mice. Behav. Neurosci. 110:1996;126-133.
    • (1996) Behav. Neurosci. , vol.110 , pp. 126-133
    • Gerlai, R.1
  • 86
    • 0028366559 scopus 로고
    • Microdialysis administration of vasopressin into the septum improves social recognition in Brattleboro rats
    • Engelmann M., Landgraf R. Microdialysis administration of vasopressin into the septum improves social recognition in Brattleboro rats. Physiol. Behav. 55:1994;145-149.
    • (1994) Physiol. Behav. , vol.55 , pp. 145-149
    • Engelmann, M.1    Landgraf, R.2
  • 87
    • 0030866899 scopus 로고    scopus 로고
    • Social interaction and sensorimotor gating abnormalities in mice lacking Dvl1
    • Lijam N., et al. Social interaction and sensorimotor gating abnormalities in mice lacking Dvl1. Cell. 90:1997;895-905.
    • (1997) Cell , vol.90 , pp. 895-905
    • Lijam, N.1
  • 88
    • 65749318026 scopus 로고
    • Two new mutants, trembler and 'Reeler', with neurological actions in the house mouse
    • Falconer D.S. Two new mutants, trembler and 'Reeler', with neurological actions in the house mouse. J. Genet. 50:1951;182-201.
    • (1951) J. Genet. , vol.50 , pp. 182-201
    • Falconer, D.S.1
  • 89
    • 0027413915 scopus 로고
    • A novel non-ataxic guinea pig strain with cerebrocortical and cerebellar abnormalities
    • Lev-Ram V., et al. A novel non-ataxic guinea pig strain with cerebrocortical and cerebellar abnormalities. Brain Res. 606:1993;325-331.
    • (1993) Brain Res. , vol.606 , pp. 325-331
    • Lev-Ram, V.1
  • 90
    • 0028342512 scopus 로고
    • Medial temporal lobe structures and autism: A review of clinical and experimental findings
    • Bachevalier J. Medial temporal lobe structures and autism: a review of clinical and experimental findings. Neuropsychologia. 32:1994;627-648.
    • (1994) Neuropsychologia , vol.32 , pp. 627-648
    • Bachevalier, J.1
  • 91
    • 0034220390 scopus 로고    scopus 로고
    • Effects of early midline cerebellar lesion on cognitive and emotional functions in the rat
    • Bobnée S., et al. Effects of early midline cerebellar lesion on cognitive and emotional functions in the rat. Behav. Brain Res. 112:2000;107-117.
    • (2000) Behav. Brain Res. , vol.112 , pp. 107-117
    • Bobnée, S.1
  • 92
    • 0035101697 scopus 로고    scopus 로고
    • Early amygdala damage in the rat as a model for neurodevelopmental psychopathological disorders
    • Wolterink G., et al. Early amygdala damage in the rat as a model for neurodevelopmental psychopathological disorders. Eur. Neuropsychopharmacol. 11:2001;51-59.
    • (2001) Eur. Neuropsychopharmacol. , vol.11 , pp. 51-59
    • Wolterink, G.1
  • 93
    • 0034612151 scopus 로고    scopus 로고
    • Prenatal exposure of rats to valproic acid reproduces the cerebellar anomalies associated with autism
    • Ingram J.L., et al. Prenatal exposure of rats to valproic acid reproduces the cerebellar anomalies associated with autism. Neurotoxicol. Teratol. 22:2000;319-324.
    • (2000) Neurotoxicol. Teratol. , vol.22 , pp. 319-324
    • Ingram, J.L.1
  • 94
    • 0033023802 scopus 로고    scopus 로고
    • Developmental brain injury associated with abnormal play behavior in neonatally Borna disease virus-infected Lewis rats: A model of autism
    • Pletnikov M.V., et al. Developmental brain injury associated with abnormal play behavior in neonatally Borna disease virus-infected Lewis rats: a model of autism. Behav. Brain Res. 100:1999;43-50.
    • (1999) Behav. Brain Res. , vol.100 , pp. 43-50
    • Pletnikov, M.V.1
  • 95
    • 0242291084 scopus 로고    scopus 로고
    • Can zebrafish be used as a model to study the neurodevelopmental causes of autism?
    • Tropepe V., Sive H.L. Can zebrafish be used as a model to study the neurodevelopmental causes of autism? Genes Brain Behav. 2:2003;268-281.
    • (2003) Genes Brain Behav. , vol.2 , pp. 268-281
    • Tropepe, V.1    Sive, H.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.