Structural determinants of efficacy at A3 adenosine receptors: Modification of the ribose moiety

Biochemical Pharmacology

Volumn 67, Issue 5, 2004, Pages 893-901

  Gao, Zhan Guo ^a   Jeong, Lak Shin ^b   Moon, Hyung Ryong ^b   Kim, Hea Ok ^b   Choi, Won Jun ^b   Shin, Dae Hong ^b   Elhalem, Eleonora ^c   Comin, Maria J ^c   Melman, Neli ^a   Mamedova, Liaman ^a   Gross, Ariel S ^a   Rodriguez, Juan B ^c   Jacobson, Kenneth A ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b Ewha Womans University   (South Korea)

^c UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

A3 adenosine receptor agonist; A3 adenosine receptor antagonist; Adenylyl cyclase; Nucleosides; Partial agonist; Phospholipase C

Indexed keywords

ADENOSINE A3 RECEPTOR AGONIST; ADENOSINE A3 RECEPTOR ANTAGONIST; RIBOSE;

ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; DRUG EFFICACY; DRUG INHIBITION; DRUG POTENCY; DRUG SELECTIVITY; DRUG TRANSFORMATION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR INTRINSIC ACTIVITY; SPECIES DIFFERENCE; SUBSTITUTION REACTION;

EID: 10744227271     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2003.10.006     Document Type: Article

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