-
1
-
-
0022495870
-
Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone
-
Adachi A., Gendelman H. E., Koenig S., Folks T., Willey R., Rabson A., Martin M. A. Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J. Virol. 59:1986;284-291.
-
(1986)
J. Virol.
, vol.59
, pp. 284-291
-
-
Adachi, A.1
Gendelman, H.E.2
Koenig, S.3
Folks, T.4
Willey, R.5
Rabson, A.6
Martin, M.A.7
-
2
-
-
0026500566
-
Cassette mutagenesis of the reverse transcriptase of human immunodeficiency virus type 1
-
Boyer P. L., Ferris A. L., Hughes S. H. Cassette mutagenesis of the reverse transcriptase of human immunodeficiency virus type 1. J. Virol. 66:1992;1031-1039.
-
(1992)
J. Virol.
, vol.66
, pp. 1031-1039
-
-
Boyer, P.L.1
Ferris, A.L.2
Hughes, S.H.3
-
3
-
-
0028024028
-
Subunit specificity of mutations that confer resistance to nonnucleoside inhibitors in human immunodeficiency virus type 1 reverse transcriptase
-
Boyer P. L., Ding J., Arnold E., Hughes S. H. Subunit specificity of mutations that confer resistance to nonnucleoside inhibitors in human immunodeficiency virus type 1 reverse transcriptase. Antimicrob. Agents Chemother. 38:1994;1909-1914.
-
(1994)
Antimicrob. Agents Chemother.
, vol.38
, pp. 1909-1914
-
-
Boyer, P.L.1
Ding, J.2
Arnold, E.3
Hughes, S.H.4
-
4
-
-
0029120982
-
Divalent cation modulation of the ribonuclease functions of human immunodeficiency virus reverse transcriptase
-
Cirino N. M., Cameron C. E., Smith J. S., Rausch J. W., Roth M. J., Benkovic S. J., Le Grice S. F. J. Divalent cation modulation of the ribonuclease functions of human immunodeficiency virus reverse transcriptase. Biochemistry. 34:1995;9936-9943.
-
(1995)
Biochemistry
, vol.34
, pp. 9936-9943
-
-
Cirino, N.M.1
Cameron, C.E.2
Smith, J.S.3
Rausch, J.W.4
Roth, M.J.5
Benkovic, S.J.6
Le, G.S.F.J.7
-
6
-
-
0032509101
-
Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 Å resolution
-
Ding J., Das K., Hsiou Y., Sarafianos S. G., Clark A. D. Jr, Jacobo-Molina A., Tantillo C., Hughes S. H., Arnold E. Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 Å resolution. J. Mol. Biol. 284:1998;1095-1111.
-
(1998)
J. Mol. Biol.
, vol.284
, pp. 1095-1111
-
-
Ding, J.1
Das, K.2
Hsiou, Y.3
Sarafianos, S.G.4
Clark A.D., Jr.5
Jacobo-Molina, A.6
Tantillo, C.7
Hughes, S.H.8
Arnold, E.9
-
7
-
-
0026664173
-
When retroviral reverse transcriptases reach the end of their RNA templates
-
Fu T.-B., Taylor J. When retroviral reverse transcriptases reach the end of their RNA templates. J. Virol. 66:1992;4271-4278.
-
(1992)
J. Virol.
, vol.66
, pp. 4271-4278
-
-
Fu, T.-B.1
Taylor, J.2
-
8
-
-
0032478535
-
Effects of mutations in the polymerase domain on the polymerase, RNase H and strand transfer activities of human immunodeficiency virus type 1 reverse transcriptase
-
Gao H.-Q., Boyer P. L., Arnold E., Hughes S. H. Effects of mutations in the polymerase domain on the polymerase, RNase H and strand transfer activities of human immunodeficiency virus type 1 reverse transcriptase. J. Mol. Biol. 277:1998;559-572.
-
(1998)
J. Mol. Biol.
, vol.277
, pp. 559-572
-
-
Gao, H.-Q.1
Boyer, P.L.2
Arnold, E.3
Hughes, S.H.4
-
9
-
-
0029645414
-
Mechanistic implications from the structure of a catalytic fragment of Moloney murine leukemia virus reverse transcriptase
-
Georgiadis M. M., Jessen S. M., Telesnitsky A., Goff S. P., Hendrickson W. A. Mechanistic implications from the structure of a catalytic fragment of Moloney murine leukemia virus reverse transcriptase. Structure. 3:1995;879-992.
-
(1995)
Structure
, vol.3
, pp. 879-992
-
-
Georgiadis, M.M.1
Jessen, S.M.2
Telesnitsky, A.3
Goff, S.P.4
Hendrickson, W.A.5
-
10
-
-
0028987115
-
Truncating alpha-helix E′ of p66 human immunodeficiency virus reverse transcriptase modulates RNase H function and impairs DNA strand transfer
-
Ghosh M., Howard K. J., Cameron C. E., Benkovic S. H., Hughes S. H., Le Grice S. F. Truncating alpha-helix E′ of p66 human immunodeficiency virus reverse transcriptase modulates RNase H function and impairs DNA strand transfer. J. Biol. Chem. 270:1995;7068-7076.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 7068-7076
-
-
Ghosh, M.1
Howard, K.J.2
Cameron, C.E.3
Benkovic, S.H.4
Hughes, S.H.5
Le, G.S.F.6
-
11
-
-
0024999452
-
Retroviral reverse transcriptase: Synthesis, structure and function
-
Goff S. P. Retroviral reverse transcriptase: synthesis, structure and function. J. Acquir. Immune Defic. Syndr. 3:1990;817-831.
-
(1990)
J. Acquir. Immune Defic. Syndr.
, vol.3
, pp. 817-831
-
-
Goff, S.P.1
-
12
-
-
0026448638
-
Human immunodeficiency virus type 1 reverse transcriptase: Spatial and temporal relationship between the polymerase and RNase H activities
-
Gopalakrishnan V., Peliska J. A., Benkovic S. J. Human immunodeficiency virus type 1 reverse transcriptase: spatial and temporal relationship between the polymerase and RNase H activities. Proc. Natl Acad. Sci. USA. 89:1992;10763-10767.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 10763-10767
-
-
Gopalakrishnan, V.1
Peliska, J.A.2
Benkovic, S.J.3
-
13
-
-
0028945841
-
HIV-1 reverse transcriptase-associated RNase H cleaves RNA/RNA in arrested complexes: Implications for the mechanism by which RNase H discriminates between RNA/RNA and RNA/DNA
-
Götte M., Fackler S., Hermann T., Perola E., Cellai L., Gross H. J., Le Grice S. F., Heumann H. HIV-1 reverse transcriptase-associated RNase H cleaves RNA/RNA in arrested complexes: implications for the mechanism by which RNase H discriminates between RNA/RNA and RNA/DNA. EMBO J. 14:1995;833-841.
-
(1995)
EMBO J.
, vol.14
, pp. 833-841
-
-
Götte, M.1
Fackler, S.2
Hermann, T.3
Perola, E.4
Cellai, L.5
Gross, H.J.6
Le, G.S.F.7
Heumann, H.8
-
14
-
-
0025975174
-
Reconstitution in vitro of RNase H activity by using purified N-terminal and C-terminal domains of human immunodeficiency virus type 1 reverse transcriptase
-
Hostomsky Z., Hostomska Z., Hudson G. O., Moomaw E. W., Nodes B. R. Reconstitution in vitro of RNase H activity by using purified N-terminal and C-terminal domains of human immunodeficiency virus type 1 reverse transcriptase. Proc. Natl Acad. Sci. USA. 88:1991;1148-1152.
-
(1991)
Proc. Natl Acad. Sci. USA
, vol.88
, pp. 1148-1152
-
-
Hostomsky, Z.1
Hostomska, Z.2
Hudson, G.O.3
Moomaw, E.W.4
Nodes, B.R.5
-
15
-
-
0028089330
-
Redesignation of the RNase D activity associated with retroviral reverse transcriptase as RNase H
-
Hostomsky Z., Hughes S. H., Goff S. P., Le Grice S. F. J. Redesignation of the RNase D activity associated with retroviral reverse transcriptase as RNase H. J. Virol. 68:1994;1970-1971.
-
(1994)
J. Virol.
, vol.68
, pp. 1970-1971
-
-
Hostomsky, Z.1
Hughes, S.H.2
Goff, S.P.3
Le, G.S.F.J.4
-
16
-
-
0030586090
-
Structure of unliganded human immunodeficiency virus type 1 reverse transcriptase at 2.7 Å resolution: Implications of conformational changes for polymerization and inhibition mechanisms
-
Hsiou Y., Ding J., Das K., Clark A. D. Jr, Hughes S. H., Arnold E. Structure of unliganded human immunodeficiency virus type 1 reverse transcriptase at 2.7 Å resolution: implications of conformational changes for polymerization and inhibition mechanisms. Structure. 4:1996;853-860.
-
(1996)
Structure
, vol.4
, pp. 853-860
-
-
Hsiou, Y.1
Ding, J.2
Das, K.3
Clark A.D., Jr.4
Hughes, S.H.5
Arnold, E.6
-
17
-
-
0002615512
-
RNase H of retroviral reverse transcriptase
-
R. J. Crouch, & J. J. Toulmé. Paris: INSERM Editions
-
Hughes S. H., Arnold E., Hostomsky Z. RNase H of retroviral reverse transcriptase. Crouch R. J., Toulmé J. J. Ribonucleases H. 1998;195-224 INSERM Editions, Paris.
-
(1998)
Ribonucleases H
, pp. 195-224
-
-
Hughes, S.H.1
Arnold, E.2
Hostomsky, Z.3
-
18
-
-
0027318776
-
Crystal structure of human immunodeficiency virus type-1 reverse transcriptase complexed with double-stranded DNA at 3.0 Å resolution shows bent DNA
-
Jacobo-Molina A., Ding J., Nanni R. G., Clark A. D. Jr, Lu X., Tantillo C., Williams R. L., Kamer G., Ferris A. L., Clark P., Hizi A., Hughes S. H., Arnold E. Crystal structure of human immunodeficiency virus type-1 reverse transcriptase complexed with double-stranded DNA at 3.0 Å resolution shows bent DNA. Proc. Natl Acad. Sci, USA. 90:1993;6320-6324.
-
(1993)
Proc. Natl Acad. Sci, USA
, vol.90
, pp. 6320-6324
-
-
Jacobo-Molina, A.1
Ding, J.2
Nanni, R.G.3
Clark A.D., Jr.4
Lu, X.5
Tantillo, C.6
Williams, R.L.7
Kamer, G.8
Ferris, A.L.9
Clark, P.10
Hizi, A.11
Hughes, S.H.12
Arnold, E.13
-
20
-
-
0025191211
-
Rapid purification of homodimer and heterodimer HIV-1 reverse transcriptase by metal chelate affinity chromatography
-
Le Grice S. F. J., Grüninger-Leitch F. Rapid purification of homodimer and heterodimer HIV-1 reverse transcriptase by metal chelate affinity chromatography. Eur. J. Biochem. 187:1990;307-314.
-
(1990)
Eur. J. Biochem.
, vol.187
, pp. 307-314
-
-
Le, G.S.F.J.1
Grüninger-Leitch, F.2
-
21
-
-
0026070438
-
Subunit-selective mutagenesis indicates minimal polymerase activity in heterodimer-associated p51 HIV-1 reverse transcriptase
-
Le Grice S. F. J., Naas T., Wohlgensinger B., Schatz O. Subunit-selective mutagenesis indicates minimal polymerase activity in heterodimer-associated p51 HIV-1 reverse transcriptase. EMBO J. 10:1991;3905-3911.
-
(1991)
EMBO J.
, vol.10
, pp. 3905-3911
-
-
Le, G.S.F.J.1
Naas, T.2
Wohlgensinger, B.3
Schatz, O.4
-
22
-
-
34250082672
-
Review of HIV reverse transcriptase three-dimensional structure: Implications for drug design
-
Nanni R. G., Ding J., Jacobo-Molina A., Arnold E., Hughes S. H. Review of HIV reverse transcriptase three-dimensional structure: implications for drug design. Perspect. Drug Discov. Des. 1:1993;129-150.
-
(1993)
Perspect. Drug Discov. Des.
, vol.1
, pp. 129-150
-
-
Nanni, R.G.1
Ding, J.2
Jacobo-Molina, A.3
Arnold, E.4
Hughes, S.H.5
-
23
-
-
0032512857
-
Control of mutation of viral plus strand synthesis by HIV reverse transcriptase
-
Palaniappan C., Kim J. K., Wisniewski M., Fay P. J., Bambara R. A. Control of mutation of viral plus strand synthesis by HIV reverse transcriptase. J. Biol. Chem. 273:1998;3808-3816.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 3808-3816
-
-
Palaniappan, C.1
Kim, J.K.2
Wisniewski, M.3
Fay, P.J.4
Bambara, R.A.5
-
24
-
-
0026486193
-
Mechanism of DNA strand transfer reactions catalyzed by HIV-1 reverse transcriptase
-
Peliska J. A., Benkovic S. J. Mechanism of DNA strand transfer reactions catalyzed by HIV-1 reverse transcriptase. Science. 258:1992;1112-1118.
-
(1992)
Science
, vol.258
, pp. 1112-1118
-
-
Peliska, J.A.1
Benkovic, S.J.2
-
25
-
-
0028842293
-
The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1
-
Rodgers D. W., Gramblin S. J., Harris B. A., Ray S., Culp J. S., Hellmig B., Woolf D. J., Debouck C., Harrison S. C. The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1. Proc. Natl Acad. Sci. USA. 92:1995;1222-1226.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 1222-1226
-
-
Rodgers, D.W.1
Gramblin, S.J.2
Harris, B.A.3
Ray, S.4
Culp, J.S.5
Hellmig, B.6
Woolf, D.J.7
Debouck, C.8
Harrison, S.C.9
-
26
-
-
0023464708
-
Vectors for selective expression of cloned DNAs by T7 RNA polymerase
-
Rosenberg A. H., Lade B. N., Chui D. S., Lin S. W., Dunn J. J., Studier F. W. Vectors for selective expression of cloned DNAs by T7 RNA polymerase. Gene. 56:1987;125-135.
-
(1987)
Gene
, vol.56
, pp. 125-135
-
-
Rosenberg, A.H.1
Lade, B.N.2
Chui, D.S.3
Lin, S.W.4
Dunn, J.J.5
Studier, F.W.6
-
27
-
-
0025267173
-
HIV-1 RT associated ribonuclease H displays both endonuclease and 3′→5′ exonuclease activity
-
Schatz O., Mous J., Le Grice S. F. J. HIV-1 RT associated ribonuclease H displays both endonuclease and 3′→5′ exonuclease activity. EMBO J. 9:1990;1171-1176.
-
(1990)
EMBO J.
, vol.9
, pp. 1171-1176
-
-
Schatz, O.1
Mous, J.2
Le, G.S.F.J.3
-
28
-
-
0027264116
-
Purification and characterization of an active human immunodeficiency virus type 1 RNase H domain
-
Smith J. S., Roth M. J. Purification and characterization of an active human immunodeficiency virus type 1 RNase H domain. J. Virol. 67:1993;4037-4049.
-
(1993)
J. Virol.
, vol.67
, pp. 4037-4049
-
-
Smith, J.S.1
Roth, M.J.2
-
29
-
-
0027931296
-
Construction of an enzymatically active ribonuclease H domain of human immunodeficiency virus type 1 reverse transcriptase
-
Stahl S. J., Kaufman J. D., Vikic-Topic S., Crouch R. J., Wingfield P. T. Construction of an enzymatically active ribonuclease H domain of human immunodeficiency virus type 1 reverse transcriptase. Protein Eng. 7:1994;1103-1108.
-
(1994)
Protein Eng.
, vol.7
, pp. 1103-1108
-
-
Stahl, S.J.1
Kaufman, J.D.2
Vikic-Topic, S.3
Crouch, R.J.4
Wingfield, P.T.5
-
30
-
-
0023042283
-
Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes
-
Studier F. W., Moffatt B. A. Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes. J. Mol. Biol. 189:1986;113-130.
-
(1986)
J. Mol. Biol.
, vol.189
, pp. 113-130
-
-
Studier, F.W.1
Moffatt, B.A.2
-
31
-
-
0024121540
-
Domain structure of the Moloney murine leukemia virus reverse transcriptase: Mutational analysis and separate expression of the DNA polymerase and RNase H activities
-
Tanese N., Goff S. P. Domain structure of the Moloney murine leukemia virus reverse transcriptase: mutational analysis and separate expression of the DNA polymerase and RNase H activities. Proc. Natl Acad. Sci. USA. 85:1988;1777-1781.
-
(1988)
Proc. Natl Acad. Sci. USA
, vol.85
, pp. 1777-1781
-
-
Tanese, N.1
Goff, S.P.2
-
32
-
-
0027518740
-
RNase H domain mutations affect the interaction between Moloney murine leukemia virus reverse transcriptase and its primer-template
-
Telesnitsky A., Goff S. P. RNase H domain mutations affect the interaction between Moloney murine leukemia virus reverse transcriptase and its primer-template. Proc. Natl Acad. Sci. USA. 90:1993;1276-1280.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 1276-1280
-
-
Telesnitsky, A.1
Goff, S.P.2
-
33
-
-
0026622006
-
Retroviral reverse transcription and integration: Progress and problems
-
Whitcomb J. M., Hughes S. H. Retroviral reverse transcription and integration: progress and problems. Annu. Rev. Cell Biol. 7:1992;275-306.
-
(1992)
Annu. Rev. Cell Biol.
, vol.7
, pp. 275-306
-
-
Whitcomb, J.M.1
Hughes, S.H.2
|