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Volumn 17, Issue , 2004, Pages 48-59

Novel QTLs for HDL levels identified in mice by controlling for Apoa2 allelic effects: Confirmation of a chromosome 6 locus in a congenic strain

Author keywords

Atherosclerosis; Lipoprotein; Quantitative trait locus

Indexed keywords

APOLIPOPROTEIN A2; HIGH DENSITY LIPOPROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; AMYLOIDOGENIC APOLIPOPROTEIN A II, MOUSE; AMYLOIDOGENIC APOLIPOPROTEIN A-II, MOUSE; CHOLESTEROL;

EID: 1842509761     PISSN: 15312267     EISSN: None     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00124.2003     Document Type: Article
Times cited : (14)

References (69)
  • 1
    • 0016838772 scopus 로고
    • Genetics of histocompatibility in mice
    • Bailey DW. Genetics of histocompatibility in mice. Immunogenetics 2: 249-256, 1975.
    • (1975) Immunogenetics , vol.2 , pp. 249-256
    • Bailey, D.W.1
  • 2
    • 0039416145 scopus 로고    scopus 로고
    • Battling heart disease
    • Breslow J. Battling heart disease. Science 273: 15, 1996.
    • (1996) Science , vol.273 , pp. 15
    • Breslow, J.1
  • 4
    • 0030941803 scopus 로고    scopus 로고
    • The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
    • Brown MS and Goldstein JL. The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 89: 331-340, 1997.
    • (1997) Cell , vol.89 , pp. 331-340
    • Brown, M.S.1    Goldstein, J.L.2
  • 5
    • 0028228359 scopus 로고
    • Linkage analysis of the genetic determinants of high density lipoprotein concentrations and composition: Evidence for involvement of the apolipoprotein A-II and cholesteryl ester transfer protein loci
    • Bu X, Warden CH, Xia YR, De Meester C, Puppione DL, Teruya S, Lokensgard B, Daneshmand S, Brown J, Gray RJ, Rotter JI, and Lusis AJ. Linkage analysis of the genetic determinants of high density lipoprotein concentrations and composition: evidence for involvement of the apolipoprotein A-II and cholesteryl ester transfer protein loci. Hum Genet 93: 639-648, 1994.
    • (1994) Hum Genet , vol.93 , pp. 639-648
    • Bu, X.1    Warden, C.H.2    Xia, Y.R.3    De Meester, C.4    Puppione, D.L.5    Teruya, S.6    Lokensgard, B.7    Daneshmand, S.8    Brown, J.9    Gray, R.J.10    Rotter, J.I.11    Lusis, A.J.12
  • 9
    • 0032848728 scopus 로고    scopus 로고
    • Association of the A-204C polymorphism in the cholesterol 7alpha-hydroxylase gene with variations in plasma low density lipoprotein cholesterol levels in the Framingham Offspring Study
    • Couture P, Otvos JD, Cupples LA, Wilson PW, Schaefer EJ, and Ordovas JM. Association of the A-204C polymorphism in the cholesterol 7alpha-hydroxylase gene with variations in plasma low density lipoprotein cholesterol levels in the Framingham Offspring Study. J Lipid Res 40: 1883-1889, 1999.
    • (1999) J Lipid Res , vol.40 , pp. 1883-1889
    • Couture, P.1    Otvos, J.D.2    Cupples, L.A.3    Wilson, P.W.4    Schaefer, E.J.5    Ordovas, J.M.6
  • 10
    • 0028842308 scopus 로고
    • Genetic basis of lipoprotein disorders
    • Dammerman M and Breslow JL. Genetic basis of lipoprotein disorders. Circulation 91: 505-512, 1995.
    • (1995) Circulation , vol.91 , pp. 505-512
    • Dammerman, M.1    Breslow, J.L.2
  • 15
    • 0025007039 scopus 로고
    • A polymorphism affecting apolipoprotein AII translational efficiency determines high density lipoprotein size and composition
    • Doolittle MH, LeBoeuf RC, Warden CH, Bee LM, and Lusis AJ. A polymorphism affecting apolipoprotein AII translational efficiency determines high density lipoprotein size and composition. J Biol Chem 265: 10380-10388, 1990.
    • (1990) J Biol Chem , vol.265 , pp. 10380-10388
    • Doolittle, M.H.1    LeBoeuf, R.C.2    Warden, C.H.3    Bee, L.M.4    Lusis, A.J.5
  • 16
    • 0028214722 scopus 로고
    • Towards high resolution maps of the mouse and human genomes: A facility for ordering markers to 01 cM resolution
    • European Backcross Collaborative Group. Towards high resolution maps of the mouse and human genomes: a facility for ordering markers to 01 cM resolution. Hum Mol Genet 3: 621-627, 1994.
    • (1994) Hum Mol Genet , vol.3 , pp. 621-627
  • 17
    • 0028844104 scopus 로고
    • Taking stock of complex trait genetics in mice
    • Frankel W. Taking stock of complex trait genetics in mice. Trends Genet 11: 471-477, 1995.
    • (1995) Trends Genet , vol.11 , pp. 471-477
    • Frankel, W.1
  • 19
    • 0015306821 scopus 로고
    • Standard karyotype of the mouse, Mus musculus
    • Committee on Standardized Genetic Nomenclature for Mice
    • Green MC et al. (Committee on Standardized Genetic Nomenclature for Mice). Standard karyotype of the mouse, Mus musculus. J Hered 63: 69-72, 1972.
    • (1972) J Hered , vol.63 , pp. 69-72
    • Green, M.C.1
  • 20
    • 0032966978 scopus 로고    scopus 로고
    • Quantitative trait locus analysis of plasma lipoprotein levels in an autoimmune mouse model: Interactions between lipoprotein metabolism, autoimmune disease, and atherogenesis
    • Gu L, Johnson MW, and Lusis AJ. Quantitative trait locus analysis of plasma lipoprotein levels in an autoimmune mouse model: interactions between lipoprotein metabolism, autoimmune disease, and atherogenesis. Arterioscler Thromb Vasc Biol 19: 442-453, 1999.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 442-453
    • Gu, L.1    Johnson, M.W.2    Lusis, A.J.3
  • 21
    • 0030935065 scopus 로고    scopus 로고
    • A hepatic lipase (LIPC) allele associated with high plasma concentrations of high density lipoprotein cholesterol
    • Guerra R, Wang J, Grundy SM, and Cohen JC. A hepatic lipase (LIPC) allele associated with high plasma concentrations of high density lipoprotein cholesterol. Proc Natl Acad Sci USA 94: 4532-4537, 1997.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4532-4537
    • Guerra, R.1    Wang, J.2    Grundy, S.M.3    Cohen, J.C.4
  • 23
    • 0027185023 scopus 로고
    • Influence of mouse apolipoprotein A-II on plasma lipoproteins in transgenic mice
    • Hedrick CC, Castellani LW, Warden CH, Puppione DL, and Lusis AJ. Influence of mouse apolipoprotein A-II on plasma lipoproteins in transgenic mice. J Biol Chem 268: 20676-20682, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 20676-20682
    • Hedrick, C.C.1    Castellani, L.W.2    Warden, C.H.3    Puppione, D.L.4    Lusis, A.J.5
  • 24
    • 0031670768 scopus 로고    scopus 로고
    • Lipoproteins and atherosclerosis
    • Hoeg JM. Lipoproteins and atherosclerosis. Endocrinol Metab Clin North Am 27: 569-584, 1998.
    • (1998) Endocrinol Metab Clin North Am , vol.27 , pp. 569-584
    • Hoeg, J.M.1
  • 25
    • 0028960739 scopus 로고
    • Structure of the human gene encoding sterol regulatory element binding protein-1 (SREBF1) and localization of SREBF1 and SREBF2 to chromosomes 17p11.2 and 22q13
    • Hua X, Wu J, Goldstein JL, Brown MS, and Hobbs HH. Structure of the human gene encoding sterol regulatory element binding protein-1 (SREBF1) and localization of SREBF1 and SREBF2 to chromosomes 17p11.2 and 22q13. Genomics 25: 667-673, 1995.
    • (1995) Genomics , vol.25 , pp. 667-673
    • Hua, X.1    Wu, J.2    Goldstein, J.L.3    Brown, M.S.4    Hobbs, H.H.5
  • 27
    • 0032900698 scopus 로고    scopus 로고
    • No common major gene for apolipoprotein A-I and HDL3-C levels: Evidence from bivariate segregation analysis
    • Juo SH, Beaty TH, Duffy DL, Coresh J, and Kwiterovich PO Jr. No common major gene for apolipoprotein A-I and HDL3-C levels: evidence from bivariate segregation analysis. Genet Epidemiol 16: 54-68, 1999.
    • (1999) Genet Epidemiol , vol.16 , pp. 54-68
    • Juo, S.H.1    Beaty, T.H.2    Duffy, D.L.3    Coresh, J.4    Kwiterovich Jr., P.O.5
  • 28
    • 0032961228 scopus 로고    scopus 로고
    • Genetic association of five apolipoprotein polymorphisms with serum lipoprotein-lipid levels in African blacks
    • Kamboh MI, Bunker CH, Aston CE, Nestlerode CS, McAllister AE, and Ukoli FA. Genetic association of five apolipoprotein polymorphisms with serum lipoprotein-lipid levels in African blacks. Genet Epidemiol 16: 205-222, 1999.
    • (1999) Genet Epidemiol , vol.16 , pp. 205-222
    • Kamboh, M.I.1    Bunker, C.H.2    Aston, C.E.3    Nestlerode, C.S.4    McAllister, A.E.5    Ukoli, F.A.6
  • 29
    • 0034980519 scopus 로고    scopus 로고
    • Two novel quantitative trait loci on mouse chromosomes 6 and 4 independently and synergistically regulate plasma apoB levels
    • Ko C, Lee TL, Lau PW, Li J, Davis BT, Voyiaziakis E, Allison DB, Chua SC Jr, and Huang LS. Two novel quantitative trait loci on mouse chromosomes 6 and 4 independently and synergistically regulate plasma apoB levels. J Lipid Res 42: 844-855, 2001.
    • (2001) J Lipid Res , vol.42 , pp. 844-855
    • Ko, C.1    Lee, T.L.2    Lau, P.W.3    Li, J.4    Davis, B.T.5    Voyiaziakis, E.6    Allison, D.B.7    Chua Jr., S.C.8    Huang, L.S.9
  • 30
    • 0028877463 scopus 로고
    • Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
    • Lander ES and Kruglyak L. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet 11: 241-247, 1995.
    • (1995) Nat Genet , vol.11 , pp. 241-247
    • Lander, E.S.1    Kruglyak, L.2
  • 31
    • 0020604267 scopus 로고
    • Genetic control of lipid transport in mice: Structural properties and polymorphisms of plasma apolipoproteins
    • LeBoeuf RC, Puppione DL, Schumaker VN, and Lusis AJ. Genetic control of lipid transport in mice: structural properties and polymorphisms of plasma apolipoproteins. J Biol Chem 258: 5063-5070, 1983.
    • (1983) J Biol Chem , vol.258 , pp. 5063-5070
    • LeBoeuf, R.C.1    Puppione, D.L.2    Schumaker, V.N.3    Lusis, A.J.4
  • 33
    • 0025144236 scopus 로고
    • cDNA cloning of human oxysterol-binding protein and localization of the gene to human chromosome 11 and mouse chromosome 19
    • Levanon D, Hsieh CL, Francke U, Dawson PA, Ridgway ND, Brown MS, and Goldstein JL. cDNA cloning of human oxysterol-binding protein and localization of the gene to human chromosome 11 and mouse chromosome 19. Genomics 7: 65-74, 1990.
    • (1990) Genomics , vol.7 , pp. 65-74
    • Levanon, D.1    Hsieh, C.L.2    Francke, U.3    Dawson, P.A.4    Ridgway, N.D.5    Brown, M.S.6    Goldstein, J.L.7
  • 34
    • 0025354122 scopus 로고
    • Towards construction of a high-resolution map of the mouse genome using PCR-analyzed microsatellites
    • Love JM, Knight AM, McAleer MA, and Todd JA. Towards construction of a high-resolution map of the mouse genome using PCR-analyzed microsatellites. Nucleic Acids Res 18: 4123-4130, 1990.
    • (1990) Nucleic Acids Res , vol.18 , pp. 4123-4130
    • Love, J.M.1    Knight, A.M.2    McAleer, M.A.3    Todd, J.A.4
  • 35
    • 0020641703 scopus 로고
    • Genetic control of lipid transport in mice: Genes controlling structure of high density lipoproteins
    • Lusis AJ, Taylor BA, Wangenstein RW, and LeBoeuf RC. Genetic control of lipid transport in mice: genes controlling structure of high density lipoproteins. J Biol Chem 258: 5071-5078, 1983.
    • (1983) J Biol Chem , vol.258 , pp. 5071-5078
    • Lusis, A.J.1    Taylor, B.A.2    Wangenstein, R.W.3    LeBoeuf, R.C.4
  • 36
    • 0042995279 scopus 로고    scopus 로고
    • Quantitative trait loci that determine lipoprotein cholesterol levels in DBA/2J and CAST/Ei inbred mice
    • Lyons MA, Wittenburg H, Li R, Walsh KA, Churchill GA, Carey MC, and Paigen B. Quantitative trait loci that determine lipoprotein cholesterol levels in DBA/2J and CAST/Ei inbred mice. J Lipid Res 44: 953-967, 2003.
    • (2003) J Lipid Res , vol.44 , pp. 953-967
    • Lyons, M.A.1    Wittenburg, H.2    Li, R.3    Walsh, K.A.4    Churchill, G.A.5    Carey, M.C.6    Paigen, B.7
  • 37
    • 0030893854 scopus 로고    scopus 로고
    • Complex genetic control of HDL levels in mice in response to an atherogenic diet: Coordinate regulation of HDL levels and bile acid metabolism
    • Machleder D, Ivandic B, Welch C, Castellani L, Reue K, and Lusis AJ. Complex genetic control of HDL levels in mice in response to an atherogenic diet: coordinate regulation of HDL levels and bile acid metabolism. J Clin Invest 99: 1406-1419, 1997.
    • (1997) J Clin Invest , vol.99 , pp. 1406-1419
    • Machleder, D.1    Ivandic, B.2    Welch, C.3    Castellani, L.4    Reue, K.5    Lusis, A.J.6
  • 38
    • 0027355585 scopus 로고
    • A Macintosh program for storage and analysis of experimental genetic mapping data
    • Manly K. A Macintosh program for storage and analysis of experimental genetic mapping data. Mamm Genome 4: 303-313, 1993.
    • (1993) Mamm Genome , vol.4 , pp. 303-313
    • Manly, K.1
  • 39
    • 0032805974 scopus 로고    scopus 로고
    • Overview of QTL mapping software and introduction to Map Manager QT
    • Manly K and Olson JM. Overview of QTL mapping software and introduction to Map Manager QT. Mamm Genome 10: 327-334, 1999.
    • (1999) Mamm Genome , vol.10 , pp. 327-334
    • Manly, K.1    Olson, J.M.2
  • 44
    • 0023157966 scopus 로고
    • Primary structure of apolipoprotein A-II from inbred mouse strain BALB/c
    • Miller CG, Lee TD, LeBoeuf RC, and Shively JE. Primary structure of apolipoprotein A-II from inbred mouse strain BALB/c. J Lipid Res 28: 311-319, 1987.
    • (1987) J Lipid Res , vol.28 , pp. 311-319
    • Miller, C.G.1    Lee, T.D.2    LeBoeuf, R.C.3    Shively, J.E.4
  • 46
    • 0003928480 scopus 로고    scopus 로고
    • Bar Harbor, ME: The Jackson Laboratory. (May)
    • Mouse Genome Database. Mouse Genome Informatics web site [Online]. Bar Harbor, ME: The Jackson Laboratory. http://www.informatics.jax.org/ (May 2003).
    • (2003) Mouse Genome Database
  • 47
    • 0031471572 scopus 로고    scopus 로고
    • Association of apo E polymorphism with plasma lipid levels in a multiethnic elderly population
    • Pablos-Mendez A, Mayeux R, Ngai C, Shea S, and Berglund L. Association of apo E polymorphism with plasma lipid levels in a multiethnic elderly population. Arterioscler Thromb Vasc Biol 17: 3534-3541, 1997.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 3534-3541
    • Pablos-Mendez, A.1    Mayeux, R.2    Ngai, C.3    Shea, S.4    Berglund, L.5
  • 49
    • 0034700636 scopus 로고    scopus 로고
    • The pharmacokinetics and pharmacodynamics of agents proven to raise high-density lipoprotein cholesterol
    • Piepho RW. The pharmacokinetics and pharmacodynamics of agents proven to raise high-density lipoprotein cholesterol. Am J Cardiol 86: 35L-40L, 2000.
    • (2000) Am J Cardiol , vol.86
    • Piepho, R.W.1
  • 51
    • 0028788492 scopus 로고
    • Genetic factors in lipoprotein metabolism: Analysis of a genetic cross between inbred mouse strains NZB/B1NJ and SM/J using a complete linkage map approach
    • Purcell-Huynh DA, Weinreb A, Castellani LW, Mehrabian M, Doolittle MH, and Lusis AJ. Genetic factors in lipoprotein metabolism: Analysis of a genetic cross between inbred mouse strains NZB/B1NJ and SM/J using a complete linkage map approach. J Clin Invest 96: 1845-1858, 1995.
    • (1995) J Clin Invest , vol.96 , pp. 1845-1858
    • Purcell-Huynh, D.A.1    Weinreb, A.2    Castellani, L.W.3    Mehrabian, M.4    Doolittle, M.H.5    Lusis, A.J.6
  • 53
    • 0033358661 scopus 로고    scopus 로고
    • Replication of linkage studies of complex traits: An examination of variation of location estimates
    • Roberts SB, MacLean CJ, Neale MC, Eaves LJ, and Kendler LS. Replication of linkage studies of complex traits: an examination of variation of location estimates. Am J Hum Genet 65: 876-884, 1999.
    • (1999) Am J Hum Genet , vol.65 , pp. 876-884
    • Roberts, S.B.1    MacLean, C.J.2    Neale, M.C.3    Eaves, L.J.4    Kendler, L.S.5
  • 54
    • 0030478149 scopus 로고    scopus 로고
    • Effect of genetic background on the contribution of New Zealand Black loci to autoimmune lupus nephritis
    • Rozzo SJ, Vyse TJ, Drake CG, and Kotzin BL. Effect of genetic background on the contribution of New Zealand Black loci to autoimmune lupus nephritis. Proc Natl Acad Sci USA 93: 15164-15168, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 15164-15168
    • Rozzo, S.J.1    Vyse, T.J.2    Drake, C.G.3    Kotzin, B.L.4
  • 56
    • 0031914643 scopus 로고    scopus 로고
    • Subcongenic analysis of the IddI3 locus in NOD/Lt mice: Evidence for several susceptibility genes including a possible diabetogenic role for β2-microglobulin
    • Serreze DV, Bridgett M, Chapman HD, Chen E, Richard SD, and Leiter EH. Subcongenic analysis of the IddI3 locus in NOD/Lt mice: evidence for several susceptibility genes including a possible diabetogenic role for β2-microglobulin. J Immunol 160: 1472-1478, 1998.
    • (1998) J Immunol , vol.160 , pp. 1472-1478
    • Serreze, D.V.1    Bridgett, M.2    Chapman, H.D.3    Chen, E.4    Richard, S.D.5    Leiter, E.H.6
  • 57
    • 0004287115 scopus 로고
    • New York: Oxford University Press
    • Silver LM. Mouse Genetics. New York: Oxford University Press, 1995.
    • (1995) Mouse Genetics
    • Silver, L.M.1
  • 58
    • 0032951977 scopus 로고    scopus 로고
    • Influence of apolipoprotein E polymorphism on serum lipids and lipoprotein changes from childhood to adulthood: The Bogalusa Heart Study
    • Srinivasan SR, Ehnholm C, Elkasabany A, and Berenson G. Influence of apolipoprotein E polymorphism on serum lipids and lipoprotein changes from childhood to adulthood: the Bogalusa Heart Study. Atherosclerosis 143: 435-443, 1999.
    • (1999) Atherosclerosis , vol.143 , pp. 435-443
    • Srinivasan, S.R.1    Ehnholm, C.2    Elkasabany, A.3    Berenson, G.4
  • 61
    • 0030741533 scopus 로고    scopus 로고
    • Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis
    • Sullivan PM, Mezdour H, Aratani Y, Knouff C, Najib J, Reddick RL, Quarfordt SH, and Nobuyo N. Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis. J Biol Chem 272: 17972-17980, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 17972-17980
    • Sullivan, P.M.1    Mezdour, H.2    Aratani, Y.3    Knouff, C.4    Najib, J.5    Reddick, R.L.6    Quarfordt, S.H.7    Nobuyo, N.8
  • 64
    • 0032520266 scopus 로고    scopus 로고
    • Linkage between cholesterol 7α-hydroxylase and high plasma low-density lipoprotein cholesterol concentrations
    • Wang J, Freeman DJ, Grundy SM, Levine DM, Guerra R, and Cohen JC. Linkage between cholesterol 7α-hydroxylase and high plasma low-density lipoprotein cholesterol concentrations. J Clin Invest 101: 1283-1291, 1998.
    • (1998) J Clin Invest , vol.101 , pp. 1283-1291
    • Wang, J.1    Freeman, D.J.2    Grundy, S.M.3    Levine, D.M.4    Guerra, R.5    Cohen, J.C.6
  • 65
    • 0036738377 scopus 로고    scopus 로고
    • Quantitative trait loci and candidate genes regulating HDL cholesterol: A murine chromosome map
    • Wang X and Paigen B. Quantitative trait loci and candidate genes regulating HDL cholesterol: a murine chromosome map. Arterioscler Thromb Vasc Biol 22: 1390-1401, 2002.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1390-1401
    • Wang, X.1    Paigen, B.2
  • 66
    • 0029992667 scopus 로고    scopus 로고
    • Dramatically decreased high density lipoprotein cholesterol, increased remnant clearance, and insulin hypersensitivity in apolipoprotein A-II knockout mice suggest a complex role for apolipoprotein A-II in atherosclerosis susceptibility
    • Weng W and Breslow JL. Dramatically decreased high density lipoprotein cholesterol, increased remnant clearance, and insulin hypersensitivity in apolipoprotein A-II knockout mice suggest a complex role for apolipoprotein A-II in atherosclerosis susceptibility. Proc Natl Acad Sci USA 93: 14788-14794, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 14788-14794
    • Weng, W.1    Breslow, J.L.2
  • 69
    • 0030140381 scopus 로고    scopus 로고
    • Production of congenic mouse strains carrying NOD-derived diabetogenic genetic intervals: An approach for the genetic dissection of complex traits
    • Yui MA, Muralidharan K, Moreno-Altamirano B, Perrin G, Chestnut K, and Wakeland EK. Production of congenic mouse strains carrying NOD-derived diabetogenic genetic intervals: an approach for the genetic dissection of complex traits. Mamm Genome 7: 331-334, 1996.
    • (1996) Mamm Genome , vol.7 , pp. 331-334
    • Yui, M.A.1    Muralidharan, K.2    Moreno-Altamirano, B.3    Perrin, G.4    Chestnut, K.5    Wakeland, E.K.6


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