메뉴 건너뛰기




Volumn 102, Issue 1, 2004, Pages 87-96

Exercise and endothelial function: Role of endothelium-derived nitric oxide and oxidative stress in healthy subjects and hypertensive patients

Author keywords

Acetylcholine; ACh; Aerobic exercise; Ang II; Angiotensin II; CGMP; Cyclic guanosine monophosphate; EDHF; Endothelial function; Endothelial nitric oxide synthase; Endothelium derived hyperpolarizing factor; ENOS; Hypertension; Nitric oxide; Oxidative stress

Indexed keywords

ANTIHYPERTENSIVE AGENT; ASCORBIC ACID; CATALASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GLUTATHIONE PEROXIDASE; HEAT SHOCK PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; NITRIC OXIDE SYNTHASE; PROSTAGLANDIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE DISMUTASE;

EID: 1842471294     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2004.02.003     Document Type: Review
Times cited : (205)

References (98)
  • 1
    • 0030811458 scopus 로고    scopus 로고
    • External iliac artery endofibrosis in athletes
    • Abraham P., Saumet J.L., Chevalier J.M. External iliac artery endofibrosis in athletes. Sports Med. 24:1997;221-226.
    • (1997) Sports Med , vol.24 , pp. 221-226
    • Abraham, P.1    Saumet, J.L.2    Chevalier, J.M.3
  • 2
    • 0027154244 scopus 로고
    • Antihypertensive mechanism of exercise
    • Arakawa K. Antihypertensive mechanism of exercise. J Hypertens. 11:1993;223-229.
    • (1993) J Hypertens , vol.11 , pp. 223-229
    • Arakawa, K.1
  • 6
    • 0029841677 scopus 로고    scopus 로고
    • Function and production of nitric oxide in the coronary circulation of the conscious dog during exercise
    • Bernstein R.D., Ochoa F.Y., Xu X., Forfia P., Shen W., Thompson C.I., Hintze T.H. Function and production of nitric oxide in the coronary circulation of the conscious dog during exercise. Circ Res. 79:1996;840-848.
    • (1996) Circ Res , vol.79 , pp. 840-848
    • Bernstein, R.D.1    Ochoa, F.Y.2    Xu, X.3    Forfia, P.4    Shen, W.5    Thompson, C.I.6    Hintze, T.H.7
  • 7
    • 0021167582 scopus 로고
    • Physical fitness and incidence of hypertension in healthy normotensive men and women
    • Blair S.N., Goodyear N.N., Gibbons L.W., Cooper K.H. Physical fitness and incidence of hypertension in healthy normotensive men and women. JAMA. 252:1984;487-490.
    • (1984) JAMA , vol.252 , pp. 487-490
    • Blair, S.N.1    Goodyear, N.N.2    Gibbons, L.W.3    Cooper, K.H.4
  • 8
    • 0035098207 scopus 로고    scopus 로고
    • Endothelial dysfunction in salt-sensitive essential hypertension
    • Bragulat E., de la Sierra A., Antonio M.T., Coca A. Endothelial dysfunction in salt-sensitive essential hypertension. Hypertension. 37:2001;444-448.
    • (2001) Hypertension , vol.37 , pp. 444-448
    • Bragulat, E.1    De La Sierra, A.2    Antonio, M.T.3    Coca, A.4
  • 9
    • 0035834823 scopus 로고    scopus 로고
    • Hsp90 and caveolin are key targets for the proangiogenic nitric oxide-mediated effects of statins
    • Brouet A., Sonveaux P., Dessy C., Moniotte S., Balligand J.L., Feron O. Hsp90 and caveolin are key targets for the proangiogenic nitric oxide-mediated effects of statins. Circ Res. 89:2001;866-873.
    • (2001) Circ Res , vol.89 , pp. 866-873
    • Brouet, A.1    Sonveaux, P.2    Dessy, C.3    Moniotte, S.4    Balligand, J.L.5    Feron, O.6
  • 10
    • 0034634281 scopus 로고    scopus 로고
    • Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress
    • Cai H., Harrison D.G. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res. 87:2000;840-844.
    • (2000) Circ Res , vol.87 , pp. 840-844
    • Cai, H.1    Harrison, D.G.2
  • 11
    • 0021354536 scopus 로고
    • Epidemiology of coronary heart disease: The Framingham study
    • Castelli W.P. Epidemiology of coronary heart disease: the Framingham study. Am J Med. 76:1984;4-12.
    • (1984) Am J Med , vol.76 , pp. 4-12
    • Castelli, W.P.1
  • 12
    • 33750733652 scopus 로고    scopus 로고
    • Chronic exercise decreases adrenergic agonist-induced vasoconstriction in spontaneously hypertensive rats
    • Chen H.I., Chiang I.P. Chronic exercise decreases adrenergic agonist-induced vasoconstriction in spontaneously hypertensive rats. Am J Physiol. 271:1996;H977-H983.
    • (1996) Am J Physiol , vol.271 , pp. 977-H983
    • Chen, H.I.1    Chiang, I.P.2
  • 13
    • 0030512279 scopus 로고    scopus 로고
    • Exercise training increases acetylcholine-stimulated endothelium-derived nitric oxide release in spontaneously hypertensive rats
    • Chen H.I., Chiang I.P., Jen C.J. Exercise training increases acetylcholine-stimulated endothelium-derived nitric oxide release in spontaneously hypertensive rats. J Biomed Sci. 3:1996;454-460.
    • (1996) J Biomed Sci , vol.3 , pp. 454-460
    • Chen, H.I.1    Chiang, I.P.2    Jen, C.J.3
  • 14
    • 0032964529 scopus 로고    scopus 로고
    • Daily exercise enhances acetylcholine-induced dilation in mesenteric and hindlimb vasculature of hypertensive rats
    • Chen Y., Collins H.L., DiCarlo S.E. Daily exercise enhances acetylcholine-induced dilation in mesenteric and hindlimb vasculature of hypertensive rats. Clin Exp Hypertens. 21:1999;353-376.
    • (1999) Clin Exp Hypertens , vol.21 , pp. 353-376
    • Chen, Y.1    Collins, H.L.2    Dicarlo, S.E.3
  • 15
    • 0038460302 scopus 로고    scopus 로고
    • The seventh report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure: The JNC 7 report
    • Chobanian A.V., Bakris G.L., Black H.R., Cushman W.C., Green L.A., Izzo J.L. Jr., Jones D.W., Materson B.J., Oparil S., Wright J.T. Jr., Roccella E.J., National Heart, Lung, and Blood Institute Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure, National High Blood Pressure Education Program Coordinating Committee The seventh report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure: the JNC 7 report. JAMA. 289:2003;2560-2572.
    • (2003) JAMA , vol.289 , pp. 2560-2572
    • Chobanian, A.V.1    Bakris, G.L.2    Black, H.R.3    Cushman, W.C.4    Green, L.A.5    Izzo Jr., J.L.6    Jones, D.W.7    Materson, B.J.8    Oparil, S.9    Wright Jr., J.T.10    Roccella, E.J.11    Heart, N.12
  • 17
    • 0035941411 scopus 로고    scopus 로고
    • Shear stress regulates endothelial nitric oxide synthase expression through c-Src by divergent signaling pathways
    • Davis M.E., Cai H., Drummond G.R., Harrison D.G. Shear stress regulates endothelial nitric oxide synthase expression through c-Src by divergent signaling pathways. Circ Res. 89:2001;1073-1080.
    • (2001) Circ Res , vol.89 , pp. 1073-1080
    • Davis, M.E.1    Cai, H.2    Drummond, G.R.3    Harrison, D.G.4
  • 18
    • 0037377576 scopus 로고    scopus 로고
    • Role of c-Src in regulation of endothelial nitric oxide synthase expression during exercise training
    • Davis M.E., Cai H., McCann L., Fukai T., Harrison D.G. Role of c-Src in regulation of endothelial nitric oxide synthase expression during exercise training. Am J Physiol Heart Circ Physiol. 284:2003;H1449-H1453.
    • (2003) Am J Physiol Heart Circ Physiol , vol.284 , pp. 1449-H1453
    • Davis, M.E.1    Cai, H.2    McCann, L.3    Fukai, T.4    Harrison, D.G.5
  • 19
    • 1542338410 scopus 로고    scopus 로고
    • Shear stress regulates endothelial nitric oxide synthase promoter activity through nuclear factor kappaB binding
    • Davis M.E., Grumbach I.M., Fukai T., Cutchins A., Harrison D.G. Shear stress regulates endothelial nitric oxide synthase promoter activity through nuclear factor kappaB binding. J Biol Chem. 2003.
    • (2003) J Biol Chem
    • Davis, M.E.1    Grumbach, I.M.2    Fukai, T.3    Cutchins, A.4    Harrison, D.G.5
  • 20
    • 0037111365 scopus 로고    scopus 로고
    • Daily exercise normalizes the number of diaphorase (NOS) positive neurons in the hypothalamus of hypertensive rats
    • DiCarlo S.E., Zheng H., Collins H.L., Rodenbaugh D.W., Patel K.P. Daily exercise normalizes the number of diaphorase (NOS) positive neurons in the hypothalamus of hypertensive rats. Brain Res. 955:2002;153-160.
    • (2002) Brain Res , vol.955 , pp. 153-160
    • Dicarlo, S.E.1    Zheng, H.2    Collins, H.L.3    Rodenbaugh, D.W.4    Patel, K.P.5
  • 21
    • 0032994228 scopus 로고    scopus 로고
    • Acute simultaneous stimulation of nitric oxide and oxygen radicals by angiotensin II in humans in vivo
    • Dijhorst-Oei L.T., Stores E.S., Koomans H.A., Rabelink T.J. Acute simultaneous stimulation of nitric oxide and oxygen radicals by angiotensin II in humans in vivo. J Cardiovasc Pharmacol. 33:1999;420-424.
    • (1999) J Cardiovasc Pharmacol , vol.33 , pp. 420-424
    • Dijhorst-Oei, L.T.1    Stores, E.S.2    Koomans, H.A.3    Rabelink, T.J.4
  • 22
    • 0033542476 scopus 로고    scopus 로고
    • Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
    • Dimmeler S., Fleming I., Fisslthaler B., Hermann C., Busse R., Zeiher A.M. Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature. 399:1999;601-605.
    • (1999) Nature , vol.399 , pp. 601-605
    • Dimmeler, S.1    Fleming, I.2    Fisslthaler, B.3    Hermann, C.4    Busse, R.5    Zeiher, A.M.6
  • 23
    • 0025294321 scopus 로고
    • Activation of endothelial L-arginine pathway in resistance arteries. Effect of age and hypertension
    • Dohi Y., Thiel M.A., Buhler F.R., Lüscher T.F. Activation of endothelial L-arginine pathway in resistance arteries. effect of age and hypertension. Hypertension. 16:1990;170-179.
    • (1990) Hypertension , vol.16 , pp. 170-179
    • Dohi, Y.1    Thiel, M.A.2    Buhler, F.R.3    Lüscher, T.F.4
  • 24
    • 0032990560 scopus 로고    scopus 로고
    • Endothelial dysfunction in human disease
    • Drexler H., Horning B. Endothelial dysfunction in human disease. J Mol Cell Cardiol. 31:1999;51-60.
    • (1999) J Mol Cell Cardiol , vol.31 , pp. 51-60
    • Drexler, H.1    Horning, B.2
  • 25
    • 0035013148 scopus 로고    scopus 로고
    • Exercise characteristics and the blood pressure response to dynamic physical training
    • Fagard R.H. Exercise characteristics and the blood pressure response to dynamic physical training. Med Sci Sports Exerc. 33:2001;1229-1233.
    • (2001) Med Sci Sports Exerc , vol.33 , pp. 1229-1233
    • Fagard, R.H.1
  • 26
    • 0033566864 scopus 로고    scopus 로고
    • Signal transduction of eNOS activation
    • Fleming I., Busse R. Signal transduction of eNOS activation. Cardiovasc Res. 43:1999;532-541.
    • (1999) Cardiovasc Res , vol.43 , pp. 532-541
    • Fleming, I.1    Busse, R.2
  • 27
    • 0037013152 scopus 로고    scopus 로고
    • Domain mapping studies reveal that the M domain of hsp90 serves as a molecular scaffold to regulate Akt-dependent phosphorylation of endothelial nitric oxide synthase and NO release
    • Fontana J., Fulton D., Chen Y., Fairchild T.A., McCabe T.J., Fujita N., Tsuruo T., Sessa W.C. Domain mapping studies reveal that the M domain of hsp90 serves as a molecular scaffold to regulate Akt-dependent phosphorylation of endothelial nitric oxide synthase and NO release. Circ Res. 90:2002;866-873.
    • (2002) Circ Res , vol.90 , pp. 866-873
    • Fontana, J.1    Fulton, D.2    Chen, Y.3    Fairchild, T.A.4    McCabe, T.J.5    Fujita, N.6    Tsuruo, T.7    Sessa, W.C.8
  • 28
    • 0034201168 scopus 로고    scopus 로고
    • Regulation of the vascular extracellular superoxide dismutase by nitric oxide and exercise training
    • Fukai T., Siegfried M.R., Ushio-Fukai M., Cheng Y., Kojda G., Harrison D.G. Regulation of the vascular extracellular superoxide dismutase by nitric oxide and exercise training. J Clin Invest. 105:2000;1631-1639.
    • (2000) J Clin Invest , vol.105 , pp. 1631-1639
    • Fukai, T.1    Siegfried, M.R.2    Ushio-Fukai, M.3    Cheng, Y.4    Kojda, G.5    Harrison, D.G.6
  • 30
    • 0035991414 scopus 로고    scopus 로고
    • Attenuation of the exercise-induced increase in skeletal muscle Flt-1 mRNA by nitric oxide synthase inhibition
    • Gavin T.P., Wagner P.D. Attenuation of the exercise-induced increase in skeletal muscle Flt-1 mRNA by nitric oxide synthase inhibition. Acta Physiol Scand. 175:2002;201-209.
    • (2002) Acta Physiol Scand , vol.175 , pp. 201-209
    • Gavin, T.P.1    Wagner, P.D.2
  • 32
    • 0030751493 scopus 로고    scopus 로고
    • Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia
    • Gerber H.P., Condorelli F., Park J., Ferrara N. Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia. J Biol Chem. 272:1997;23659-23667.
    • (1997) J Biol Chem , vol.272 , pp. 23659-23667
    • Gerber, H.P.1    Condorelli, F.2    Park, J.3    Ferrara, N.4
  • 33
    • 0041572924 scopus 로고    scopus 로고
    • The effect of different intensities of exercise on endothelium-dependent vasodilation in humans: Role of endothelium-dependent nitric oxide and oxidative stress
    • Goto C., Higashi Y., Kimura M., Noma K., Hara K., Nakagawa K., Kawamura M., Chayama K., Yoshizumi M., Nara I. The effect of different intensities of exercise on endothelium-dependent vasodilation in humans: role of endothelium-dependent nitric oxide and oxidative stress. Circulation. 108:2003;530-535.
    • (2003) Circulation , vol.108 , pp. 530-535
    • Goto, C.1    Higashi, Y.2    Kimura, M.3    Noma, K.4    Hara, K.5    Nakagawa, K.6    Kawamura, M.7    Chayama, K.8    Yoshizumi, M.9    Nara, I.10
  • 34
    • 0028043672 scopus 로고
    • Modification of forearm resistance vessels by exercise training in young men
    • Green D.J., Cable T., Fox C., Rankin J.M., Taylor R.R. Modification of forearm resistance vessels by exercise training in young men. J Appl Physiol. 77:1994;1829-1833.
    • (1994) J Appl Physiol , vol.77 , pp. 1829-1833
    • Green, D.J.1    Cable, T.2    Fox, C.3    Rankin, J.M.4    Taylor, R.R.5
  • 35
    • 0032749162 scopus 로고    scopus 로고
    • Exercise training improves endothelium-mediated vasorelaxation after chronic coronary occlusion
    • Griffin K.L., Laughlin M.H., Parker J.L. Exercise training improves endothelium-mediated vasorelaxation after chronic coronary occlusion. J Appl Physiol. 87:1999;1948-1956.
    • (1999) J Appl Physiol , vol.87 , pp. 1948-1956
    • Griffin, K.L.1    Laughlin, M.H.2    Parker, J.L.3
  • 36
    • 0033069767 scopus 로고    scopus 로고
    • 1999 Guideline for the management of mild hypertension: Memorandum from World Health Organization/International Society of Hypertension meeting
    • Guidelines Sub-Committee 1999 Guideline for the management of mild hypertension: memorandum from World Health Organization/International Society of Hypertension meeting. J Hypertens. 17:1999;151-183.
    • (1999) J Hypertens , vol.17 , pp. 151-183
    • Sub-Committee, G.1
  • 37
    • 0035219833 scopus 로고    scopus 로고
    • Exercise-induced angiogenesis-related growth and transcription factors in skeletal muscle, and their modification in muscle pathology
    • Gustafsson T., Kraus W.E. Exercise-induced angiogenesis-related growth and transcription factors in skeletal muscle, and their modification in muscle pathology. Front Biosci. 6:2001;D75-D89.
    • (2001) Front Biosci , vol.6 , pp. 75-D89
    • Gustafsson, T.1    Kraus, W.E.2
  • 38
    • 0028937231 scopus 로고
    • Effects of L-arginine infusion on renal hemodynamics in patients with mild essential hypertension
    • Higashi Y., Oshima T., Ozono R., Watanabe M., Matsuura H., Kajiyama G. Effects of L-arginine infusion on renal hemodynamics in patients with mild essential hypertension. Hypertension. 25:1995;898-902.
    • (1995) Hypertension , vol.25 , pp. 898-902
    • Higashi, Y.1    Oshima, T.2    Ozono, R.3    Watanabe, M.4    Matsuura, H.5    Kajiyama, G.6
  • 40
    • 0033554460 scopus 로고    scopus 로고
    • Regular aerobic exercise augments endothelium-dependent vascular relaxation in normotensive as well as hypertensive subjects: Role of endothelium-derived nitric oxide
    • Higashi Y., Sasaki S., Kurisu S., Yoshimizu A., Ssaki N., Matsuura H., Kajiyama G., Oshima T. Regular aerobic exercise augments endothelium-dependent vascular relaxation in normotensive as well as hypertensive subjects: role of endothelium-derived nitric oxide. Circulation. 100:1999;1194-1202.
    • (1999) Circulation , vol.100 , pp. 1194-1202
    • Higashi, Y.1    Sasaki, S.2    Kurisu, S.3    Yoshimizu, A.4    Ssaki, N.5    Matsuura, H.6    Kajiyama, G.7    Oshima, T.8
  • 41
    • 0034049445 scopus 로고    scopus 로고
    • A comparison of angiotensin-converting enzyme inhibitors, calcium antagonists, beta-blockers, diuretics on reactive hyperemia in patients with essential hypertension: A multicenter study
    • Higashi Y., Sasaki S., Nakagawa K., Kurisu S., Yoshimizu A., Matsuura H., Kajiyama G., Oshima T. A comparison of angiotensin-converting enzyme inhibitors, calcium antagonists, beta-blockers, diuretics on reactive hyperemia in patients with essential hypertension: A multicenter study. J Am Coll Cardiol. 35:2000;284-291.
    • (2000) J Am Coll Cardiol , vol.35 , pp. 284-291
    • Higashi, Y.1    Sasaki, S.2    Nakagawa, K.3    Kurisu, S.4    Yoshimizu, A.5    Matsuura, H.6    Kajiyama, G.7    Oshima, T.8
  • 43
    • 0036100972 scopus 로고    scopus 로고
    • Tetrahydrobiopterin improves impaired endothelium-dependent vasodilation in patients with essential hypertension
    • Higashi Y., Sasaki S., Nakagawa K., Fukuda Y., Matsuura H., Oshima T., Chayama K. Tetrahydrobiopterin improves impaired endothelium-dependent vasodilation in patients with essential hypertension. Am J Hypertens. 15:2002;326-332.
    • (2002) Am J Hypertens , vol.15 , pp. 326-332
    • Higashi, Y.1    Sasaki, S.2    Nakagawa, K.3    Fukuda, Y.4    Matsuura, H.5    Oshima, T.6    Chayama, K.7
  • 44
    • 0032862719 scopus 로고    scopus 로고
    • Superoxide dismutase gene expression in skeletal muscle: Fiber-specific adaptation to endurance training
    • Hollander J., Fiebig R., Gore M., Bejma J., Ookawara T., Ohno H., Ji L.L. Superoxide dismutase gene expression in skeletal muscle: fiber-specific adaptation to endurance training. Am J Physiol. 277:1999;R856-R862.
    • (1999) Am J Physiol , vol.277 , pp. 856-R862
    • Hollander, J.1    Fiebig, R.2    Gore, M.3    Bejma, J.4    Ookawara, T.5    Ohno, H.6    Ji, L.L.7
  • 45
    • 0026525559 scopus 로고
    • Angiogenesis in skeletal and cardiac muscle
    • Hudlicka O., Brown M., Egginton S. Angiogenesis in skeletal and cardiac muscle. Physiol Rev. 72:1992;369-417.
    • (1992) Physiol Rev , vol.72 , pp. 369-417
    • Hudlicka, O.1    Brown, M.2    Egginton, S.3
  • 46
    • 0029890099 scopus 로고    scopus 로고
    • Shear stress modulates expression of Cu/Zn superoxide dismutase in human aortic endothelial cells
    • Inoue N., Ramasamy S., Fukai T., Nerem R.M., Harrison D.G. Shear stress modulates expression of Cu/Zn superoxide dismutase in human aortic endothelial cells. Circ Res. 79:1996;32-37.
    • (1996) Circ Res , vol.79 , pp. 32-37
    • Inoue, N.1    Ramasamy, S.2    Fukai, T.3    Nerem, R.M.4    Harrison, D.G.5
  • 47
    • 0033886373 scopus 로고    scopus 로고
    • Oxidant signaling in vascular cell growth, death and survival: A review of the roles of reactive oxygen species in smooth muscle and endothelial cell mitogenic and apoptotic signaling
    • Irani K. Oxidant signaling in vascular cell growth, death and survival: A review of the roles of reactive oxygen species in smooth muscle and endothelial cell mitogenic and apoptotic signaling. Cir Res. 87:2000;179-183.
    • (2000) Cir Res , vol.87 , pp. 179-183
    • Irani, K.1
  • 48
    • 0026438913 scopus 로고
    • Glutathione and antioxidant enzymes in skeletal muscle: Effects of fiber type and exercise intensity
    • Ji L.L., Fu R., Mitchell E.W. Glutathione and antioxidant enzymes in skeletal muscle: Effects of fiber type and exercise intensity. J Appl Physiol. 73:1992;1854-1859.
    • (1992) J Appl Physiol , vol.73 , pp. 1854-1859
    • Ji, L.L.1    Fu, R.2    Mitchell, E.W.3
  • 49
    • 0036893288 scopus 로고    scopus 로고
    • Antioxidant enzyme expression in health and disease: Effects of exercise and hypertension
    • Johnson P. Antioxidant enzyme expression in health and disease: Effects of exercise and hypertension. Comp Biochem Physiol C Toxicol Pharmacol. 133:2002;493-505.
    • (2002) Comp Biochem Physiol C Toxicol Pharmacol , vol.133 , pp. 493-505
    • Johnson, P.1
  • 51
    • 0030975752 scopus 로고    scopus 로고
    • Four weeks of cycle training increases basal production of nitric oxide from the forearm
    • Kingwell B.A., Sherrard B., Jennings G.L., Dart A.M. Four weeks of cycle training increases basal production of nitric oxide from the forearm. Am J Physiol. 272:1997;H1070-H1077.
    • (1997) Am J Physiol , vol.272 , pp. 1070-H1077
    • Kingwell, B.A.1    Sherrard, B.2    Jennings, G.L.3    Dart, A.M.4
  • 52
    • 0036046755 scopus 로고    scopus 로고
    • Contribution of nitric oxide, angiotensin II, and superoxide dismutase to exercise-induced attenuation of blood pressure elevation in spontaneously hypertensive rats
    • Kohno H., Furukawa S., Naito H., Minamitani K., Ohmori D., Yamakura F. Contribution of nitric oxide, angiotensin II, and superoxide dismutase to exercise-induced attenuation of blood pressure elevation in spontaneously hypertensive rats. Jpn Heart J. 43:2002;25-34.
    • (2002) Jpn Heart J , vol.43 , pp. 25-34
    • Kohno, H.1    Furukawa, S.2    Naito, H.3    Minamitani, K.4    Ohmori, D.5    Yamakura, F.6
  • 54
    • 0343920844 scopus 로고    scopus 로고
    • Physical training improves flow-mediated dilation in patients with the polymetabolic syndrome
    • Lavrencic A., Salobir B.G., Keber I. Physical training improves flow-mediated dilation in patients with the polymetabolic syndrome. Arterioscler Thromb Vasc Biol. 20:2000;551-555.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 551-555
    • Lavrencic, A.1    Salobir, B.G.2    Keber, I.3
  • 55
    • 0031800475 scopus 로고    scopus 로고
    • Gene therapy for therapeutic myocardial angiogenesis: A promising synthesis of two emerging technologies
    • Lee J.S., Feldman A.M. Gene therapy for therapeutic myocardial angiogenesis: a promising synthesis of two emerging technologies. Nat Med. 4:1998;739-742.
    • (1998) Nat Med , vol.4 , pp. 739-742
    • Lee, J.S.1    Feldman, A.M.2
  • 56
    • 0037405671 scopus 로고    scopus 로고
    • Angiogenic growth factor expression in rat skeletal muscle in response to exercise training
    • Lloyd P.G., Prior B.M., Yang H.T., Terjung R.L. Angiogenic growth factor expression in rat skeletal muscle in response to exercise training. Am J Physiol Heart Circ Physiol. 284:2003;H1668-H1678.
    • (2003) Am J Physiol Heart Circ Physiol , vol.284 , pp. 1668-H1678
    • Lloyd, P.G.1    Prior, B.M.2    Yang, H.T.3    Terjung, R.L.4
  • 57
    • 0025289182 scopus 로고
    • Imbalance of endothelium-derived relaxing and contracting factors
    • Lüscher T.F. Imbalance of endothelium-derived relaxing and contracting factors. Am J Hypertens. 3:1990;317-330.
    • (1990) Am J Hypertens , vol.3 , pp. 317-330
    • Lüscher, T.F.1
  • 58
    • 0035919684 scopus 로고    scopus 로고
    • Effects of exercise training of 8 weeks and detraining on plasma levels of endothelium-derived factors, endothelin-1 and nitric oxide, in healthy young humans
    • Maeda S., Miyauchi T., Kakiyama T., Sugawara J., Iemitsu M., Irukayama-Tomobe Y., Murakami H., Kumagai Y., Kuno S., Matsuda M. Effects of exercise training of 8 weeks and detraining on plasma levels of endothelium-derived factors, endothelin-1 and nitric oxide, in healthy young humans. Life Sci. 69:2001;1005-1016.
    • (2001) Life Sci , vol.69 , pp. 1005-1016
    • Maeda, S.1    Miyauchi, T.2    Kakiyama, T.3    Sugawara, J.4    Iemitsu, M.5    Irukayama-Tomobe, Y.6    Murakami, H.7    Kumagai, Y.8    Kuno, S.9    Matsuda, M.10
  • 59
    • 0025231931 scopus 로고
    • Controlled trial of aerobic exercise in hypertension
    • Martin J.E., Dubbert P.M., Cushman W.C. Controlled trial of aerobic exercise in hypertension. Circulation. 81:1990;1560-1567.
    • (1990) Circulation , vol.81 , pp. 1560-1567
    • Martin, J.E.1    Dubbert, P.M.2    Cushman, W.C.3
  • 60
    • 0342285129 scopus 로고
    • Role of sympathetic efferent nerves in blood pressure regulation and in hypertension
    • Mathias C.J. Role of sympathetic efferent nerves in blood pressure regulation and in hypertension. Hypertension. 18(5 Suppl.):1991;III22-III30.
    • (1991) Hypertension , vol.18 , Issue.5 SUPPL. , pp. 22-III30
    • Mathias, C.J.1
  • 62
    • 0023790176 scopus 로고
    • Enhanced release of endothelium-derived factors by chronic increases in blood flow
    • Miller V.M., Vanhoutte P.M. Enhanced release of endothelium-derived factors by chronic increases in blood flow. Am J Physiol. 255:1988;H446-H451.
    • (1988) Am J Physiol , vol.255 , pp. 446-H451
    • Miller, V.M.1    Vanhoutte, P.M.2
  • 63
    • 0031044132 scopus 로고    scopus 로고
    • Integrin signaling transduces shear stress-dependent vasodilation of coronary arterioles
    • Muller J.M., Chilian W.M., Davis M.J. Integrin signaling transduces shear stress-dependent vasodilation of coronary arterioles. Circ Res. 80:1997;320-326.
    • (1997) Circ Res , vol.80 , pp. 320-326
    • Muller, J.M.1    Chilian, W.M.2    Davis, M.J.3
  • 64
    • 0030462545 scopus 로고    scopus 로고
    • Cardiovascular effects of exercise: Role of endothelial shear stress
    • Niebauer J., Cooke J.P. Cardiovascular effects of exercise: Role of endothelial shear stress. J Am Coll Cardiol. 28:1996;1652-1660.
    • (1996) J Am Coll Cardiol , vol.28 , pp. 1652-1660
    • Niebauer, J.1    Cooke, J.P.2
  • 65
    • 0032906078 scopus 로고    scopus 로고
    • Effects of voluntary exercise and L-arginine on thrombogenesis and microcirculation in stroke-prone spontaneously hypertensive rats
    • Noguchi T., Sasaki Y., Seki J., Giddings J.C., Yamamoto J. Effects of voluntary exercise and L-arginine on thrombogenesis and microcirculation in stroke-prone spontaneously hypertensive rats. Clin Exp Pharmacol Physiol. 26:1999;330-335.
    • (1999) Clin Exp Pharmacol Physiol , vol.26 , pp. 330-335
    • Noguchi, T.1    Sasaki, Y.2    Seki, J.3    Giddings, J.C.4    Yamamoto, J.5
  • 66
    • 0034861020 scopus 로고    scopus 로고
    • Skeletal muscle capillarity and angiogenic mRNA levels after exercise training in normoxia and chronic hypoxia
    • Olfert I.M., Breen E.C., Mathieu-Costello O., Wagner P.D. Skeletal muscle capillarity and angiogenic mRNA levels after exercise training in normoxia and chronic hypoxia. J Appl Physiol. 91:2001;1176-1184.
    • (2001) J Appl Physiol , vol.91 , pp. 1176-1184
    • Olfert, I.M.1    Breen, E.C.2    Mathieu-Costello, O.3    Wagner, P.D.4
  • 67
    • 0027475199 scopus 로고
    • The association of changes in physical-activity level and other lifestyle characteristics with mortality among men
    • Paffenbarger R.S., Hyde R.T., Wing A.L.et al. The association of changes in physical-activity level and other lifestyle characteristics with mortality among men. N Engl J Med. 328:1993;538-545.
    • (1993) N Engl J Med , vol.328 , pp. 538-545
    • Paffenbarger, R.S.1    Hyde, R.T.2    Wing, A.L.3
  • 68
    • 0025283892 scopus 로고
    • Abnormal endothelium-dependent vascular relaxation in patients with essential hypertension
    • Panza J.A., Quyyumi A.A., Brush J.E. Jr., Epstein S.E. Abnormal endothelium-dependent vascular relaxation in patients with essential hypertension. N Engl J Med. 323:1990;22-27.
    • (1990) N Engl J Med , vol.323 , pp. 22-27
    • Panza, J.A.1    Quyyumi, A.A.2    Brush, J.E.Jr.3    Epstein, S.E.4
  • 69
    • 0027161713 scopus 로고
    • Role of endothelium-derived nitric oxide in the abnormal endothelium-dependent vascular relaxation of patients with essential hypertension
    • Panza J.A., Casino P.R., Kilcoyne C.M., Quyyumi A.A. Role of endothelium-derived nitric oxide in the abnormal endothelium-dependent vascular relaxation of patients with essential hypertension. Circulation. 87:1993;1468-1474.
    • (1993) Circulation , vol.87 , pp. 1468-1474
    • Panza, J.A.1    Casino, P.R.2    Kilcoyne, C.M.3    Quyyumi, A.A.4
  • 70
    • 0027192366 scopus 로고
    • Nitric oxide and the kidney
    • Raij L. Nitric oxide and the kidney. Circulation. 87(Suppl. V):1993;V26-V29.
    • (1993) Circulation , vol.87 , Issue.SUPPL. V , pp. 26-V29
    • Raij, L.1
  • 71
    • 0030005713 scopus 로고    scopus 로고
    • Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation
    • Rajagopalan S., Kurz S., Munzel T.et al. Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. J Clin Invest. 97:1996;1916-1923.
    • (1996) J Clin Invest , vol.97 , pp. 1916-1923
    • Rajagopalan, S.1    Kurz, S.2    Munzel, T.3
  • 72
    • 0036084824 scopus 로고    scopus 로고
    • Postexercise alpha-adrenergic receptor hyporesponsiveness in hypertensive rats is due to nitric oxide
    • Rao S.P., Collins H.L., DiCarlo S.E. Postexercise alpha-adrenergic receptor hyporesponsiveness in hypertensive rats is due to nitric oxide. Am J Physiol Regul Integr Comp Physiol. 282:2002;R960-R968.
    • (2002) Am J Physiol Regul Integr Comp Physiol , vol.282 , pp. 960-R968
    • Rao, S.P.1    Collins, H.L.2    Dicarlo, S.E.3
  • 73
    • 0033209906 scopus 로고    scopus 로고
    • Role of angiotensin and oxidative stress in essential hypertension
    • Romero J.C., Reckelhoff J.F. Role of angiotensin and oxidative stress in essential hypertension. Hypertension. 34:1999;943-949.
    • (1999) Hypertension , vol.34 , pp. 943-949
    • Romero, J.C.1    Reckelhoff, J.F.2
  • 74
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis: An inflammatory disease
    • Ross R. Atherosclerosis: An inflammatory disease. N Engl J Med. 340:1999;115-126.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 75
    • 0037377579 scopus 로고    scopus 로고
    • Exercise training regulates SOD-1 and oxidative stress in porcine aortic endothelium
    • Rush J.W., Turk J.R., Laughlin M.H. Exercise training regulates SOD-1 and oxidative stress in porcine aortic endothelium. Am J Physiol Heart Circ Physiol. 284:2003;H1378-H1387.
    • (2003) Am J Physiol Heart Circ Physiol , vol.284 , pp. 1378-H1387
    • Rush, J.W.1    Turk, J.R.2    Laughlin, M.H.3
  • 76
    • 0034681429 scopus 로고    scopus 로고
    • Estrogen stimulates heat shock protein 90 binding to endothelial nitric oxide synthase in human vascular endothelial cells. Effects on calcium sensitivity and NO release
    • Russell K.S., Haynes M.P., Caulin-Glaser T., Rosneck J., Sessa W.C., Bender J.R. Estrogen stimulates heat shock protein 90 binding to endothelial nitric oxide synthase in human vascular endothelial cells. Effects on calcium sensitivity and NO release. J Biol Chem. 275:2000;5026-5030.
    • (2000) J Biol Chem , vol.275 , pp. 5026-5030
    • Russell, K.S.1    Haynes, M.P.2    Caulin-Glaser, T.3    Rosneck, J.4    Sessa, W.C.5    Bender, J.R.6
  • 78
    • 0028925799 scopus 로고
    • Comparison of effects of angiotensin I-converting enzyme inhibition and β-blockade for 2 years on function of small arteries from hypertensive patients
    • Schiffrin E.L., Deng L.Y. Comparison of effects of angiotensin I-converting enzyme inhibition and β-blockade for 2 years on function of small arteries from hypertensive patients. Hypertension. 25:1995;699-703.
    • (1995) Hypertension , vol.25 , pp. 699-703
    • Schiffrin, E.L.1    Deng, L.Y.2
  • 79
    • 0026773942 scopus 로고
    • Adhesion is required for protein kinase C-dependent activation of the Na+/H+ antiporter by platelet-derived growth factor
    • Schwartz M.A., Lechene C. Adhesion is required for protein kinase C-dependent activation of the Na+/H+ antiporter by platelet-derived growth factor. Proc Natl Acad Sci USA. 89:1992;6138-6141.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 6138-6141
    • Schwartz, M.A.1    Lechene, C.2
  • 80
    • 0028118896 scopus 로고
    • Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression
    • Sessa W.C., Pritchard K., Seyedi N., Wang J., Hintze T. Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression. Circ Res. 74:1994;349-353.
    • (1994) Circ Res , vol.74 , pp. 349-353
    • Sessa, W.C.1    Pritchard, K.2    Seyedi, N.3    Wang, J.4    Hintze, T.5
  • 81
    • 0029908623 scopus 로고    scopus 로고
    • Comparative effects of exercise training on transcription of antioxidant enzyme and the activity in old rat heart
    • Somani S.M., Rybak L.P. Comparative effects of exercise training on transcription of antioxidant enzyme and the activity in old rat heart. Indian J Physiol Pharmacol. 40:1996;205-212.
    • (1996) Indian J Physiol Pharmacol , vol.40 , pp. 205-212
    • Somani, S.M.1    Rybak, L.P.2
  • 82
    • 0028951135 scopus 로고
    • Effect of exercise training on antioxidant system in brain regions of rat
    • Somani S.M., Ravi R., Rybak L.P. Effect of exercise training on antioxidant system in brain regions of rat. Pharmacol Biochem Behav. 50:1995;635-639.
    • (1995) Pharmacol Biochem Behav , vol.50 , pp. 635-639
    • Somani, S.M.1    Ravi, R.2    Rybak, L.P.3
  • 83
    • 0037142095 scopus 로고    scopus 로고
    • Hypertension, angiotensin II, and oxidative stress
    • Sowers J.R. Hypertension, angiotensin II, and oxidative stress. N Engl J Med. 346:2002;1999-2001.
    • (2002) N Engl J Med , vol.346 , pp. 1999-2001
    • Sowers, J.R.1
  • 84
    • 0028805056 scopus 로고
    • The interstitium of the human arterial wall contains very large amounts of extracellular superoxide dismutase
    • Stralin P., Karlsson K., Johansson B.O., Marklund S.L. The interstitium of the human arterial wall contains very large amounts of extracellular superoxide dismutase. Arterioscler Thromb Vasc Biol. 11:1995;2032-2036.
    • (1995) Arterioscler Thromb Vasc Biol , vol.11 , pp. 2032-2036
    • Stralin, P.1    Karlsson, K.2    Johansson, B.O.3    Marklund, S.L.4
  • 85
    • 0032499667 scopus 로고    scopus 로고
    • Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension
    • Taddei S., Virdis A., Ghiadoni L., Magagna A., Salvetti A. Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension. Circulation. 97:1998;2222-2229.
    • (1998) Circulation , vol.97 , pp. 2222-2229
    • Taddei, S.1    Virdis, A.2    Ghiadoni, L.3    Magagna, A.4    Salvetti, A.5
  • 87
    • 0031833126 scopus 로고    scopus 로고
    • Laminar shear stress: Mechanisms by which endothelial cells transduce an atheroprotective force
    • Traub O., Berk B.C. Laminar shear stress: Mechanisms by which endothelial cells transduce an atheroprotective force. Arterioscler Thromb Vasc Biol. 18:1998;677-685.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 677-685
    • Traub, O.1    Berk, B.C.2
  • 88
    • 0027475176 scopus 로고
    • Hypertension and left ventricular hypertrophy are associated with impaired endothelium-mediated relaxation in human coronary resistance vessels
    • Treasure C.B., Klein J.L., Vita J.A., Manoukian S.V., Renwick G.H., Selwyn A.P., Ganz P., Alexander R.W. Hypertension and left ventricular hypertrophy are associated with impaired endothelium-mediated relaxation in human coronary resistance vessels. Circulation. 87:1993;86-93.
    • (1993) Circulation , vol.87 , pp. 86-93
    • Treasure, C.B.1    Klein, J.L.2    Vita, J.A.3    Manoukian, S.V.4    Renwick, G.H.5    Selwyn, A.P.6    Ganz, P.7    Alexander, R.W.8
  • 89
    • 0028823506 scopus 로고
    • Fluid shear stress stimulates mitogen-activated protein kinase in endothelial cells
    • Tseng H., Peterson T.E., Berk B.C. Fluid shear stress stimulates mitogen-activated protein kinase in endothelial cells. Circ Res. 77:1995;869-878.
    • (1995) Circ Res , vol.77 , pp. 869-878
    • Tseng, H.1    Peterson, T.E.2    Berk, B.C.3
  • 91
    • 0038342017 scopus 로고    scopus 로고
    • Oxidative stress, exercise, and antioxidant supplementation
    • Urso M.L., Clarkson P.N. Oxidative stress, exercise, and antioxidant supplementation. Toxicology. 189:2003;41-54.
    • (2003) Toxicology , vol.189 , pp. 41-54
    • Urso, M.L.1    Clarkson, P.N.2
  • 92
    • 0027491127 scopus 로고
    • Chronic exercise enhances endothelium-mediated dilation of epicardial coronary artery in conscious dogs
    • Wang J., Wolin M.S., Hintze T.H. Chronic exercise enhances endothelium-mediated dilation of epicardial coronary artery in conscious dogs. Circ Res. 73:1993;829-838.
    • (1993) Circ Res , vol.73 , pp. 829-838
    • Wang, J.1    Wolin, M.S.2    Hintze, T.H.3
  • 93
    • 0027194559 scopus 로고
    • Contribution of prostaglandins to exercise-induced vasodilation in humans
    • Willson J.R., Kapoor S.C. Contribution of prostaglandins to exercise-induced vasodilation in humans. Am J Physiol. 265:1993;H171-H175.
    • (1993) Am J Physiol , vol.265 , pp. 171-H175
    • Willson, J.R.1    Kapoor, S.C.2
  • 94
    • 0025820598 scopus 로고
    • The effects on plasma lipoproteins of a prudent weight-reducing diet, with or without exercise, in overweight men and women
    • Wood P.D., Stefanick M.L., Williams P.T., Haskell W.L. The effects on plasma lipoproteins of a prudent weight-reducing diet, with or without exercise, in overweight men and women. N Engl J Med. 325:1991;461-466.
    • (1991) N Engl J Med , vol.325 , pp. 461-466
    • Wood, P.D.1    Stefanick, M.L.2    Williams, P.T.3    Haskell, W.L.4
  • 95
    • 0036790571 scopus 로고    scopus 로고
    • Role of heat shock proteins in atherosclerosis
    • Xu Q. Role of heat shock proteins in atherosclerosis. Arterioscler Thromb Vasc Biol. 22:2002;1547-1559.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1547-1559
    • Xu, Q.1
  • 96
    • 0033532699 scopus 로고    scopus 로고
    • Exercise provides direct biphasic cardioprotection via manganese superoxide dismutase activation
    • Yamashita N., Hoshida S., Otsu K., Asahi M., Kuzuya T., Hori M. Exercise provides direct biphasic cardioprotection via manganese superoxide dismutase activation. J Exp Med. 189:1999;1699-1706.
    • (1999) J Exp Med , vol.189 , pp. 1699-1706
    • Yamashita, N.1    Hoshida, S.2    Otsu, K.3    Asahi, M.4    Kuzuya, T.5    Hori, M.6
  • 97
    • 0028790485 scopus 로고
    • Chronic exercise enhances endothelium-mediated dilation in spontaneously hypertensive rats
    • Yen M.H., Tang J.H., Sheu J.R., Lee Y.M., Ding Y.A. Chronic exercise enhances endothelium-mediated dilation in spontaneously hypertensive rats. Life Sci. 57:1995;2205-2213.
    • (1995) Life Sci , vol.57 , pp. 2205-2213
    • Yen, M.H.1    Tang, J.H.2    Sheu, J.R.3    Lee, Y.M.4    Ding, Y.A.5
  • 98
    • 0034085114 scopus 로고    scopus 로고
    • Vascular NADH/NADPH oxidase is involved in enhanced superoxide production in spontaneously hypertensive rats
    • Zalba G., Beaumont F.J., San Jose G., Fortuno A., Fortuno M.A., Etayo J.C., Diez J. Vascular NADH/NADPH oxidase is involved in enhanced superoxide production in spontaneously hypertensive rats. Hypertension. 35:2000;1055-1061.
    • (2000) Hypertension , vol.35 , pp. 1055-1061
    • Zalba, G.1    Beaumont, F.J.2    San Jose, G.3    Fortuno, A.4    Fortuno, M.A.5    Etayo, J.C.6    Diez, J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.