Identification and developmental expression of the zebrafish orthologue of the tumor suppressor gene HIC1

Biochimica et Biophysica Acta - Gene Structure and Expression

Volumn 1678, Issue 1, 2004, Pages 57-66

  Bertrand, Stéphanie ^a   Pinte, Sébastien ^b   Stankovic Valentin, Nicolas ^b   Deltour Balerdi, Sophie ^b,c   Guérardel, Cateline ^b,d   Bégue, Agnès ^b   Laudet, Vincent ^a   Leprince, Dominique ^b  

^a UNIVERSITÉ DE LYON   (France)

^b INSTITUT PASTEUR DE LILLE   (France)

^c IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^d ACADEMIA SINICA   (Taiwan)

Author keywords

17p13.3; BTB POZ; Danio rerio; HIC1; Miller Dieker syndrome

Indexed keywords

GENE PRODUCT; HYPERMETHYLATED IN CANCER PROTEIN 1; ONCOPROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; BRAIN; CARBOXY TERMINAL SEQUENCE; CHROMOSOME; DNA BINDING MOTIF; EMBRYO; EXON; EYE; GENE EXPRESSION; GENE IDENTIFICATION; GENE STRUCTURE; HEAD; IN VITRO STUDY; INTRON; MESENCHYME; NERVOUS TISSUE; NONHUMAN; NOSE; NUCLEOTIDE SEQUENCE; ORTHOLOGY; PARALOGY; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; SEQUENCE HOMOLOGY; TISSUE DISTRIBUTION; TUMOR SUPPRESSOR GENE; ZEBRA FISH; ZINC FINGER MOTIF;

AMINO ACID SEQUENCE; ANIMALS; CLONING, MOLECULAR; DNA-BINDING PROTEINS; GENES, TUMOR SUPPRESSOR; MESODERM; MOLECULAR SEQUENCE DATA; SEQUENCE ALIGNMENT; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS; ZEBRAFISH; ZEBRAFISH PROTEINS;

ACRONICTA LEPORINA; DANIO; DANIO RERIO; VERTEBRATA;

EID: 1842453272     PISSN: 01674781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbaexp.2004.01.009     Document Type: Article

References (30)

1. Ko L.J., Prives C. P53: puzzle and paradigms. Genes Dev. 10:1996;1054-1072.
2. Baylin S.B., Herman J.G., Graff J.R., Vertino P.M., Issa J.P. Alterations in DNA methylation: a fundamental aspect of neoplasia. Adv. Cancer Res. 72:1998;139-196.
3. Baylin S.B., Esteller M., Rountree M.R., Bachman K.E., Schuebel K., Hermann J.G. Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer. Hum. Mol. Genet. 10:2001;687-692.
4. Rood B.R., Zhang H., Weitman D.M., Cogen P.H. Hypermethylation of HIC-1 and 17p allelic losses in medulloblastoma. Cancer Res. 62:2002;3794-3797.
5. Chen W.Y., Zeng X., Carter M.G., Morell C.N., Chiu Yen R.-W., Esteller M., Watkins D.N., Herman J.G., Mankowski J.L., Baylin S.B. Heterozygous deletion of Hic1 predisposes mice to a gender-dependent spectrum of malignant tumors. Nat. Genet. 33:2003;197-202.
6. Makos-Wales M., Biel M., El Deiry W., Nelkin B.D., Issa J.P., Cavenee W.K., Kuerbitz S.J., Baylin S.B. p53 activates expression of HIC1, a new candidate tumor suppressor gene on 17p13.3. Nature. 1:1995;570-577.
7. Guérardel C., Deltour S., Pinte S., Monté D., Bègue A., Godwin A.K., Leprince D. Identification in the human candidate tumor suppressor gene HIC-1 of a new major alternative TATA-less promoter positively regulated by p53. J. Biol. Chem. 276:2001;3078-3089.
8. Carter M.G., Johns M.A., Zeng X., Zhou L., Zink M.C., Mankowski J.L., Donovan D.M., Baylin S.B. Mice deficient in the candidate tumor suppressor gene HIC1 exhibit developmental defects of structures affected in the Miller-Dieker syndrome. Hum. Mol. Genet. 9:2000;413-419.
9. Yingling J., Toyo-Oka K., Wynshaw-Boris A. Miller-Dieker syndrome: analysis of a human contiguous gene syndrome in the mouse. Am. J. Hum. Genet. 73:2003;475-488.
10. Wynshaw-Boris A., Gambello M.J. LIS1 and dynein motor function in neuronal migration and development. Genes Dev. 15:2001;639-651.
11. Cardoso C., Leventer R.J., Ward H.L., Toyo-Oka K., Chung J., Martin C.L., Allanson J., Pils D.T., Olney A.H., Mutchinick O.M., Hirotsune S., Wynshaw-Boris A., Dobyns W.B., Ledbetter D.H. Refinement of a 400-kb critical region allows phenotypic differentiation between isolated lissencephaly, Miller-Dieker syndrome and other phenotypes secondary to deletions of 17p13.3. Am. J. Hum. Genet. 72:2003;918-930.
12. Grimm C., Spörle R., Schmid T.E., Adler I.-D., Adamski A., Schughart K., Graw J. Isolation and embryonic expression of the novel mouse gene Hic1, the homologue of HIC1, a candidate gene for the Miller-Dieker syndrome. Hum. Mol. Genet. 8:1999;697-710.
13. Batanian J.R., Ledbetter S., Wolff R.K., Nakamura Y., White R., Dobyns W.B., Ledbetter D.H. Rapid diagnosis of Miller-Dieker syndrome and isolated lissencephaly sequence by the polymerase chain reaction. Hum. Genet. 85:1990;555-559.
14. Bardwell V.J., Treisman R. The POZ domain: a conserved protein-protein interaction motif. Genes Dev. 8:1994;1664-1677.
15. Albagli O., Dhordain P., Deweindt C., Lecocq G., Leprince D. The BTB/POZ domain: a new protein-protein interaction motif common to DNA- and actin-binding proteins. Cell Growth Differ. 6:1995;1193-1198.
16. Collins T., Stone J.R., Williams A.J. All in the family: the BTB/POZ, KRAB and SCAN domains. Mol. Cell. Biol. 21:2001;3609-3615.
17. Deltour S., Guérardel C., Leprince D. Recruitment of SMRT/N-CoR-mSin3A-HDAC-repressing complexes is not a general mechanism for BTB/POZ transcriptional repressors: the case of HIC1 and γFBP-B. Proc. Natl. Acad. Sci. U. S. A. 96:1999;14831-14836.
18. Liu Q., Shalaby F., Puri M.C., Tang S., Breitman M.L. Novel zinc finger proteins that interact with the mouse γF-crystallin promoter and are expressed in the sclerotome during early embryogenesis. Dev. Biol. 165:1994;165-177.
19. Deltour S., Pinte S., Guérardel C., Leprince D. Characterization of HRG22, a human homologue of the putative tumor suppressor gene HIC1. Biochem. Biophys. Res. Comm. 287:2001;427-434.
20. Deltour S., Pinte S., Guérardel C., Wasylyk B., Leprince D. The human tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif. Mol. Cell. Biol. 22:2002;4890-4901.
21. Guérardel C., Deltour S., Leprince D. Evolutionary divergence in the Broad complex, tramtrack and bric à brac/poxviruses and zinc finger domain from the candidate tumor suppressor gene Hypermethylated in Cancer. FEBS Lett. 451:1999;253-256.
22. Ahmad K.F., Engel C.K., Prive G.G. Crystal structure of the BTB domain from PLZF. Proc. Natl. Acad. Sci. U. S. A. 95:1998;12123-12128.
23. Melnick A., Ahmad K.F., Arai S., Polinger A., Ball H., Borden K.L., Carlile G.W., Privé G.G., Licht J.D. In-depth mutational analysis of the promyelocytic leukemia zinc finger BTB/POZ domain reveals motifs and residues required for biological and transcriptional functions. Mol. Cell. Biol. 20:2000;6550-6567.
24. Zhang Q., Yao H., Vo N., Goodman R.H. Acetylation of Adenovirus E1A regulates binding of the transcriptional repressor CtBP. Proc. Natl. Acad. Sci. U. S. A. 97:2000;14323-14328.
25. Vo N., Fjeld C., Goodman R.H. Acetylation of Nuclear hormone receptor-interacting protein RIP140 regulates binding of the transcriptional repressor CtBP. Mol. Cell. Biol. 21:2001;6181-6188.
26. Madison D.L., Yaciuk P., Kwok R.P.S., Lundblad J.R. Acetylation of the adenovirus-transforming protein E1A determines nuclear localization by disrupting association with Importin-α J. Biol. Chem. 277:2002;38755- 38763.
27. Chinnadurai G. CtBP, an unconventional transcriptional corepressor in development and oncogenesis. Mol. Cell. 9:2002;213-224.
28. Pavletich N.P., Pabo C.O. Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers. Science. 261:1993;1701-1707.
29. Deltour S., Guérardel C., Stehelin D., Leprince D. The carboxy-terminal end of the tumor suppressor gene HIC-1 is phylogenetically conserved. B.B.A. 1443:1998;230-232.
30. Redemann N., Gaul U., Jackle H. Disruption of a putative Cys-zinc interaction eliminates the biological activity of the Krüppel finger protein. Nature. 332:1988;90-92.