Limb deformity proteins: Role in mesodermal induction of the apical ectodermal ridge

Development

Volumn 124, Issue 1, 1997, Pages 133-139

  Kuhlman, Julie ^a   Niswander, Lee ^a  

^a NONE

Author keywords

Apical ectodermal ridge; Fibroblast growth factor; Limb deformity; Sonic hedgehog

Indexed keywords

FIBROBLAST GROWTH FACTOR; PROTEIN; RNA;

ANIMAL TISSUE; ARTICLE; CHIMERA; ECTODERM; EMBRYO; EMBRYO DEVELOPMENT; EMBRYO PATTERN FORMATION; GENETIC MARKER; LIMB DEFORMITY; LIMB DEVELOPMENT; MESODERM; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CHICK EMBRYO; CHICKENS; CHIMERA; ECTODERM; EMBRYO, NONMAMMALIAN; EMBRYONIC INDUCTION; FIBROBLAST GROWTH FACTOR 4; FIBROBLAST GROWTH FACTOR 8; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GROWTH SUBSTANCES; HEDGEHOG PROTEINS; HOMEODOMAIN PROTEINS; LIMB BUD; MESODERM; MICE; MICE, MUTANT STRAINS; MUSCLE, SKELETAL; PROTEIN BIOSYNTHESIS; PROTO-ONCOGENE PROTEINS; QUAIL; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; WNT PROTEINS;

ANIMALIA; ERINACEIDAE;

EID: 0031020325     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Chan, D. C., Wynshaw-Boris, A. and Leder, P. (1995). Formin isoforms are differentially expressed in the mouse embryo and are required for normal expression of fgf-4 and shh in the limb bud. Development 121, 3151-3162.
2. Cohn, M. J., Izpisúa-Belmonte, J. C., Abud, H., Heath, J. K. and Tickle, C. (1995). Fibroblast growth factors induce additional limb development from the flank of chick embryos. Cell 80, 739-746.
3. Crossley, P. H. and Martin, G. R. (1995). The mouse Fgf-8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo. Development 121, 439-451.
4. Crossley, P. H., Minowada, G., MacArthur, C. A. and Martin, G. R. (1996). Roles for FGF8 in the induction, initiation, and maintenance of chick limb development. Cell 84, 127-136.
5. Dealy, C. N. and Kosher, R. A. (1996). IGF-I, insulin and FGFs induce outgrowth of the limb buds of amelic mutant chick embryos. Development 122, 1323-1330.
6. Dush, M. K. and Martin, G. R. (1992). Analysis of mouse EVX genes; Evx-1 displays graded expression in the primitive streak. Dev. Biol. 151, 273-287.
7. Echelard, Y., Epstein, D., St-Jacques, B., Shen, L., Mohler, J., McMahon, J. A. and McMahon, A. P. (1993). Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell 75, 1417-1430.
8. Fallon, J. F., Lopez, A., Ros, M. A., Savage, M. P., Olwin, B. B. and Simandl, B. K. (1994). FGF-2: Apical ectodermal ridge growth signal for chick limb development. Science 264, 104-107.
9. Gavin, B. J., McMahon, J. A. and McMahon, A. P. (1990). Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development. Genes Dev. 4, 2319-2332.
10. Geduspan, J. S., Padanilam, B. J. and Solursh, M. (1992). Coordinate expression of IGF-I and its receptor during limb outgrowth. Dev. Dynamics 195, 67-73.
11. Green, B. N., Jones, S. B., Streck, R. D., Wood, T. L., Rotwein, P. and Pintar, J. E. (1994). Distinct expression patterns of insulin-like growth factor binding proteins 2 and 5 during fetal and postnatal development. Endocrinology 134, 954-962.
12. Hamburger, V. and Hamilton, H. (1951). A series of normal stages in the development of the chick embyros. J. Morphol. 88, 49-92.
13. Haramis, A. G., Brown, J. M. and Zeller, R. (1995). The limb deformity mutation disrupts the SHH/FGF-4 feedback loop and regulation of 5′ HoxD genes during limb pattern formation. Development 121, 4237-4245.
14. Hébert, J. M., Basilico, C., Goldfarb, M., Haub, O. and Martin, G. R. (1990). Isolation of cDNAs encoding four mouse FGF family members and characterization of their expression patterns during embryogenesis. Dev. Biol. 138, 454-463.
15. Henrique, D., Adam, J., Myat, A., Chitnis, A., Lewis, J. and Ish-Horowicz, D. (1995). Expression of a Delta homologue in prospective neurons in the chick. Nature 375, 787-790.
16. Hinchliffe, J. R. and Johnson, D. R. (1980). The Development of the Vertebrate Limb: An approach through experiment, genetics, and evolution. Oxford: Clarendon Press
17. Jackson-Grusby, L., Kuo, A. and Leder, P. (1992). A variant limb deformity transcript expressed in the embryonic mouse limb defines a novel formin. Genes Dev. 6, 29-37.
18. Jorquera, B. and Pugin, E. (1971). Sur le comportement du mésoderme et de l'ectoderme du bourgeon de membre dans les éschanges entre le poulet et le rat. Crit. Rev. Acad. Sci. Paris 272D, 1522-1525.
19. Kleinebrecht, J., Selow, J. and Winkler, W. (1982). The mouse mutant limb-deformity (Id). Anat. Anz. 152, 313-324.
20. Laufer, E., Nelson, C., Johnson, R. L., Morgan, B. A. and Tabin, C. (1994) Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud. Cell 79, 993-1003.
21. Martin, P. (1990). Tissue patterning in the developing mouse limb. Int. J. Dev. Biol. 34, 323-326.
22. Niswander, L., Jeffrey, S., Martin, G. R. and Tickle, C. (1994). Positive feedback loop coordinates growth and patterning in the vertebrate limb. Nature 371, 609-612.
23. Niswander, L. and Martin, G. R. (1993a). FGF-4 and BMP-2 have opposite effects on limb growth. Nature 361, 68-71.
24. Niswander, L. and Martin, G. R. (1993b). FGF-4 regulates expression of Evx-1 in the developing mouse limb. Development 119, 287-294.
25. Niswander, L., Tickle, C., Vogel, A., Booth, I. and Martin, G. R. (1993). FGF-4 replaces the apical ectodermal ridge and direct outgrowth and patterning of the limb. Cell 75, 579-587.
26. Ohuchi, H., Nakagawa, T., Yamauchi, M., Ohata, T., Yoshioka, H., Kuwana, T., Mima, T., Mikawa, T., Nohno, T. and Noji, S. (1995). An additional limb can be induced from the flank of the chick embryo by FGF4. Biochem. Biophys. Res. Comm. 209, 809-816.
27. Riddle, R. D., Johnson, R. L., Laufer, E. and Tabin, C. (1993). Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75, 1401-1416.
28. Saunders, J. W., Jr. (1948). The proximo-distal sequence of origin of the parts of the chick wing and the role of the ectoderm. J. Exp. Zool. 108, 363-403.
29. Streck, R. D., Wood, T. L., Hsu, M.-S. and Pintar, J. E. (1992). Insulin-like growth factor I and II and insulin-like growth factor binding protein-2 RNAs are expressed in adjacent tissues within rat embryonic and fetal limbs. Dev. Biol. 151, 586-596.
30. Summerbell, D. (1974). A quantitative analysis of the effect of excision of the AER from the chick limb-bud. J. Embryol. exp. Morph. 32, 651-660.
31. Tabin, C. J. (1991). Retinoids, homeoboxes, and growth factors: toward molecular models for limb development. Cell 66, 199-217.
32. Tickle, C. and Eichele, G. (1994). Vertebrate limb development. Annu. Rev. Cell Biol. 10, 121-152.
33. Trumpp, A., Blundell, P. A., de la Pompa, J. L. and Zeller, R. (1992). The chicken limb deformity gene encodes nuclear proteins expressed in specific cell types during morphogenesis. Genes Dev. 6, 14-28.
34. Vogel, A., Rodriguez, C. and Izpisúa-Belmonte, J.-C. (1996). Involvement of FGF-8 in initiation, outgrowth and patterning of the venebrate limb. Development 122, 1737-1750.
35. Vogel, A. and Tickle, C. (1993). FGF-4 maintains polarizing activity of posterior limb bud cells in vivo and in vitro. Development 119, 199-206.
36. Wanek, N., Muneoka, K., Holler-Dinsmore, G., Burton, R. and Bryant, S. V. (1989). A staging system for mouse limb development. J. Exp. Zool. 249, 41-49.
37. Wilkinson, D. G. (1993). Whole mount in situ hybridization of vertebrate embryos. In In Situ Hybridization (ed. D. G. Wilkinson), pp. 75-83. Oxford: Oxford University Press.
38. Woychik, R. P., Generoso, W. M., Russell, L. B., Cain, K. T., Cacheiro, N. L. A., Bultman, S. J., Selby, P. B., Dickinson, M. E., Hogan, B. L. M. and Rutledge, J. C. (1990a). Molecular and genetic characterization of a radiation-induced structural rearrangement in mouse chromosome 2 causing mutations at the limb deformity and agouti loci. Proc. Nat. Acad. Sci. USA 87, 2588-2592.
39. Woychik, R. P., Maas, R. L., Zeller, R., Vogt, T. F. and Leder, P. (1990b). 'Formins': proteins deduced from the alternative transcripts of the limb deformity gene. Nature 346, 850-853.
40. Woychik, R. P., Stewart, T. A., Davis, L. G., D'Eustachio, P. and Leder, P. (1985). An inherited limb deformity created by insertional mutagenesis in a transgenic mouse. Nature 318, 36-40.
41. Zeller, R., Jackson-Grusby, L. and Leder, P. (1989). The limb deformity gene is required for apical ectodermal ridge differentiation and anteroposterior limb pattern formation. Genes Dev. 3, 1481-1492.