A review of leukofiltration in cardiac surgery: The time course of reperfusion injury may facilitate study design of anti-inflammatory effects

Perfusion

Volumn 17, Issue SUPPL., 2002, Pages 53-62

  Ortolano, Girolamo A ^a   Aldea, Gabriel S ^a   Lilly, Kevin ^a   O'Gara, Paul ^a   Alkon, Joseph D ^a   Madera, Frederick ^a   Murad, Tarek ^a   Altenbern, Charles S ^a   Tritt, Charles S ^a   Capetandes, Anthony ^a   Gikakis, Nicolas S ^a   Wenz, Barry ^a   Shemin, Richard J ^a   Downey III, Francis X ^a  

^a PALL CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BLOOD AUTOTRANSFUSION; BLOOD FILTER; BLOOD FILTRATION; CARDIOPLEGIA; CARDIOPULMONARY BYPASS; CELL SEPARATION; CLINICAL PROTOCOL; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; COST BENEFIT ANALYSIS; DEVICE; FEMALE; HEALTH CARE COST; HEART SURGERY; HEMOFILTRATION; HUMAN; IMMUNOPATHOGENESIS; INFLAMMATORY INFILTRATE; LEUKOCYTE; LEUKOPENIA; LUNG ARTERY PRESSURE; LUNG FUNCTION; MALE; MEDICAL TECHNOLOGY; NEUTROPHIL CHEMOTAXIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REPERFUSION INJURY; SAMPLE SIZE; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; TREATMENT OUTCOME; BLOOD SALVAGE; CHEST TUBE; FILTRATION; HEART OUTPUT; IN VITRO STUDY; INTRAOPERATIVE PERIOD; LEUKOCYTE ACTIVATION; LEUKOFILTRATION; LUNG VASCULAR RESISTANCE; NEUTROPENIA; PILOT STUDY;

CARDIAC SURGICAL PROCEDURES; HEMOFILTRATION; HUMANS; LEUKAPHERESIS; REPERFUSION INJURY; TIME FACTORS;

EID: 18344394544     PISSN: 02676591     EISSN: None     Source Type: Journal    
DOI: 10.1191/0267659102pf553oa     Document Type: Article

References (86)

1. Studies of controlled reperfusion after ischemia: XIX. Reperfusate composition: Benefits of blood cardioplegia over fluosol DA cardioplegia during regional reperfusion - Importance of including blood components in reperfusate
2. Lowering reperfusion pressure reduces the injury after pulmonary ischemia
3. Controlled pulmonary reperfusion: What is the optimal method of delivery?
4. Tissue destruction by neutrophils
5. The role of neutrophils in myocardial ischemia-reperfusion injury
6. Role of platelet-activating factor in cardiovascular pathophysiology
7. Strategies for targeting complement inhibitors in ischaemia/reperfusion injury
8. Targeting the complement system
9. Therapeutic inhibition of the complement system. Y2K update
10. Phagocytes and oxidative stress
11. Respiratory muscle function and free radicals: From cell to COPD
12. Reactive oxygen species and oxidative DNA damage
13. Pharmacology of selectin inhibitors in ischemia/reperfusion states
14. Adhesion molecules: Clinical implications
15. Role of the beta2-integrins and immunoglobulin superfamily members in myocardial ischemia-reperfusion
16. Modifying risk for extracorporeal circulation: Trial of four anti-inflammatory strategies
17. Leukodepletion and aprotinin improve clinical outcome after extracorporeal circulation
18. The effects of pulsatile flow on the leukocyte depleting qualities of the Pall LG6 leukocyte depleting arterial line filter: A laboratory investigation
19. Laboratory investigation of the Pall LG 6 leukocyte depleting arterial line filter
20. Studies on the effects of Pall leucocyte filters LG 6 and AV6 in an in vitro simulated extracorporeal circulatory system
21. Laboratory studies on the effect of Pall extracorporeal filters LG6 and AV6 on patients undergoing coronary bypass grafts
22. Depletion of activated neutrophils by a filter during cardiac valve surgery
23. Filtration of activated granulocytes during cardiopulmonary bypass surgery: A morphologic and immunologic study to characterize the trapped leukocytes
24. Clinical evaluation of the LeukoGuard (LG-6) arterial line filter for routine open-heart surgery
25. Cost effectiveness of using a leucodepletion arterial line filter
26. Leukocyte depletion reduces postoperative oxygen requirements
27. Depletion of neutrophils by filtration during aortocoronary bypass surgery transiently improves postoperative cardiorespiratory status
28. Effects on complement, granulocytes and platelets of a leukocyte depletion filter during in vitro extracorporeal circulation
29. Leukocyte filtration during cardiopulmonary bypass hardly changed leucocyte counts and did not influence myeloperoxidase, complement, cytokines or platelets
30. Leukocyte filtration during cardiopulmonary reperfusion in coronary artery bypass surgery
31. The influence of leukocyte filtration during cardiopulmonary bypass on postoperative lung function. A clinical study
32. Inline leukocyte filtration during bypass. Clinical results from a randomised prospective trial
33. Does activated neutrophil depletion on bypass by leukocyte filtration reduce myocardial damage? A preliminary report
34. Preservation of platelet reactivity with leucocyte reduction
35. Evaluation of leukocyte-reducing arterial line filter (LG6) for post-operative lung function, using cardiopulmonary bypass
36. Timing of leukocyte filtration during cardiopulmonary bypass
37. Leukocyte filtration in the early reperfusion phase on cardiopulmonary bypass reduces myocardial injury
38. Efficiency and safety of leukocyte filtration during cardiopulmonary bypass for cardiac surgery
39. Are the occasional high line pressure gradients associated with leucocyte reducing filters and oxygenators a similar phenomenon?
40. Leucodepletion during cardiopulmonary bypass reduces blood transfusion and crystalloid requirements
41. Mechanisms of myocardial reperfusion injury
42. Myocardial protection: An overview
43. The role of leucocyte depletion in reducing injury to myocardium and lung during cardiopulmonary bypass
44. Efficacy of leukocyte filters in the bypass circuit for infants undergoing cardiac operations
45. Detrimental effects of cardiopulmonary bypass in cyanotic infants: Preventing the reoxygenation injury
46. Pediatric myocardial protection: An overview
47. Hypoxia, reoxygenation and the role of systemic leukodepletion in pediatric heart surgery
48. Myocardial protection in hypoxic immature hearts
49. Leukocyte-depleted reperfusion of transplanted human hearts prevents ultrastructural evidence of reperfusion injury
50. Leukocyte-depleted reperfusion of transplanted human hearts: A randomized, double-blind clinical trial
51. Evaluation of leukocyte-depleted terminal blood cardioplegic solution in patients undergoing elective and emergency coronary artery bypass grafting
52. Leukocyte depletion attenuates reperfusion injury in patients with left ventricular hypertrophy
53. Myocardial protection with leukocyte depletion in cardiac surgery
54. Leukocyte-depleted blood cardioplegia reduces cardiac troponin T release in patients undergoing coronary artery bypass grafting
55. Clinical evaluation of leukocyte-depleted blood cardioplegia for pediatric open heart operation
56. The effects of using a leukocyte removal filter during cold blood cardioplegia
57. Clinical evaluation of a leukocyte-depleting blood cardioplegia filter (BC1B) for elective open-heart surgery
58. Clinical evaluation of the new Pall leucocyte-depleting blood cardioplegia filter (BC1)
59. Single leukocyte filter (Pall BC1B) fails in multidose cold blood cardioplegia
60. Pulmonary implications of filtering various mediators of morbidity found in salvaged blood
61. Risk neutralization in cardiac surgery with leukocyte reducing filters
62. Leukocyte depletion results in improved lung function and reduced inflammatory response after cardiac surgery
63. White cell depletion of residual blood after normothermic CPB
64. Effect of anticoagulation protocol on outcome in patients undergoing CABG with heparin-bonded cardiopulmonary bypass circuits
65. Heparin-bonded circuits improve clinical outcomes in emergency coronary artery bypass grafting
66. Enhanced blood conservation in primary coronary artery bypass surgery using heparin-bonded circuits with lower anticoagulation
67. Acute respiratory failure in the adult: 2
68. Ventilation - Perfusion inequality in patients undergoing cardiac surgery
69. Prospects for understanding and eliminating the deleterious effects of cardiopulmonary bypass
70. Leukocyte depletion and implications for the prevention of reperfusion injury
71. Potential for reduction in morbidity and cost with total leucocyte control for cardiac surgery
72. Inflammatory response to cardiopulmonary bypass
73. Amplification of the inflammatory response: Adhesion molecules associated with platelet/ white cell responses
74. Upregulation of Mac-1 surface expression on neutrophils during simulated extracorporeal circulation
75. Endothelial and leukocyte adhesion molecules in inflammation and disease
76. Levels of complement factor C3 and its activated product, C3a, in operatively salvaged blood
77. Leukocyte CD11b and CD18 expression are increased in blood salvaged for autotransfusion
78. Neutrophil elastase promotes lung microvascular injury and proteolysis of endothelial cadherin
79. Leukocyte depletion during cardiac operation: A new approach through the venous bypass circuit
80. Microhemodynamics and leukocyte sequestration after pulmonary ischemia and reperfusion in rabbits
81. Neutrophil interactions with endothelium and platelets: Possible role in the development of cardiovascular injury
82. Leukocyte capillary plugging in myocardial ischemia and reperfusion in the dog
83. Correlation between ICAM-1 and functional recovery of piglet myocardium with leukocyte depleted reperfusion