Leucodepletion during cardiopulmunory bypass reduces blood transfusion and crystalloid requirements

Perfusion

Volumn 16, Issue 1, 2001, Pages 51-58

  Stefanou, D C ^a   Gourlay, T ^a   Asimakopoulos, G ^a   Taylor, K M ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; LACTOFERRIN; MYELOPEROXIDASE; BIOLOGICAL MARKER; CRYSTALLOID SOLUTIONS; ISOTONIC SOLUTION; PEROXIDASE; PLASMA SUBSTITUTE;

ANTIGEN EXPRESSION; ARTERIAL BLOOD; ARTICLE; BLOOD FILTER; BLOOD SAMPLING; BLOOD TRANSFUSION; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CONVALESCENCE; CRYSTALLOID; ELECTIVE SURGERY; FEMALE; HEART MUSCLE REVASCULARIZATION; HOSPITAL PATIENT; HUMAN; INFLAMMATION; LEUKOPENIA; MALE; NEUTROPHIL; PARAMETER; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PRIORITY JOURNAL; PROGNOSIS; PROTEIN SYNTHESIS; RANDOMIZED CONTROLLED TRIAL; REGULATORY MECHANISM; BLEEDING; BLOOD; CHEMISTRY; COMPARATIVE STUDY; ENZYMOLOGY; FILTRATION; INSTRUMENTATION; LEUKOCYTE; LEUKOCYTE COUNT; LYMPHOCYTE DEPLETION; MIDDLE AGED; STATISTICS; TREATMENT OUTCOME;

BIOLOGICAL MARKERS; BLOOD LOSS, SURGICAL; BLOOD TRANSFUSION; CARDIOPULMONARY BYPASS; FEMALE; FILTRATION; HUMANS; INFLAMMATION; ISOTONIC SOLUTIONS; LACTOFERRIN; LEUKOCYTE COUNT; LEUKOCYTES; LYMPHOCYTE DEPLETION; MACROPHAGE-1 ANTIGEN; MALE; MIDDLE AGED; MYOCARDIAL REVASCULARIZATION; NEUTROPHILS; PEROXIDASE; PLASMA SUBSTITUTES; POSTOPERATIVE PERIOD; PROGNOSIS; SURGICAL PROCEDURES, ELECTIVE; TREATMENT OUTCOME;

EID: 0034746784     PISSN: 02676591     EISSN: None     Source Type: Journal    
DOI: 10.1177/026765910101600108     Document Type: Article

References (20)

1. Prospects for understanding and eliminating the deleterious effects of cardiopulmonary bypass
2. Inflammatory response to cardiopulmonary bypass. Mechanisms involved and possible therapeutic strategies
3. Neutrophil expression of CD11b/CD18 and IL-8 secretion during normothermic cardiopulmonary bypass
4. Myeloperoxidase and elastase as markers of leukocyte activation during cardiopulmonary bypass in humans
5. Plasma levels of main granulocyte components during cardiopulmonary bypass
6. In vitro evaluation of new surface coatings for extracorporeal circulation
7. Reduction in blood loss and blood use after cardiopulmonary bypass with high dose aprotinin (Trasylol)
8. Aprotinin and methylprednisolone equally blunt cardiopulmonary bypass-induced inflammation in humans
9. Laboratory evaluation of the Pall LG6 leukocyte depleting arterial line filter
10. The effects of pulsatile flow on the leukocyte depleting qualities of the Pall LG6 leukocyte depleting filter: A laboratory investigation
11. Time course of beta 2-integrin CD11b/CD18 (Mac-1, alpha M beta 2) upregulation on neutrophils and monocytes after coronary artery bypass grafting. CD11b upregulation after CABG surgery
12. Leukocyte depletion results in improved lung function and reduced inflammatory response after cardiac surgery
13. Leukocyte and platelet depletion with a blood cell separator: Effects on lung injury after cardiac surgery with cardiopulmonary bypass
14. Leucocyte filtration during cardiopulmonary bypass hardly changed leucocyte counts and did not influence myeloperoxidase, complement, cytokines or platelets
15. Leukocyte depletion attenuates reperfusion injury in patients with left ventricular hypertrophy
16. Effects of depletion of leukocytes and platelets on cardiac dysfunction after cardiopulmonary bypass
17. The effects of cardiopulmonary bypass on fibrin formation and lysis: Is a normal fibrinolytic response essential?
18. Amplification of the inflammatory response: Adhesion molecules associated with platelet/white cell responses