Leucocyte filtration during cardiopulmonary bypass hardly changed leucocyte counts and did not influence myeloperoxidase, complement, cytokines or platelets

Perfusion

Volumn 13, Issue 6, 1998, Pages 429-436

  Baksaas, S T ^a,d   Videm, V ^b   Mollnes, T E ^c   Tollofsrud S ^a   Hetland, G ^a   Pedersen, T ^a   Svennevig, J L ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

^c UNIVERSITY OF TROMSØ   (Norway)

^d OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT; CYTOKINE; INTERLEUKIN 6; MYELOPEROXIDASE;

ADULT; AGED; ARTICLE; CARDIOPULMONARY BYPASS; CELL ACTIVATION; CLINICAL ARTICLE; CLINICAL TRIAL; COMPLEMENT ACTIVATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY BYPASS SURGERY; ELECTIVE SURGERY; EXTRACORPOREAL CIRCULATION; FEMALE; FILTRATION; HEART FAILURE; HEMODYNAMICS; HUMAN; LEUKOCYTE; LEUKOCYTE COUNT; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REVASCULARIZATION; THROMBOCYTE;

EID: 0031788602     PISSN: 02676591     EISSN: None     Source Type: Journal    
DOI: 10.1177/026765919801300606     Document Type: Article

References (27)

1. Kirklin JK. The postperfusion syndrome: inflammation and the damaging effects of cardiopulmonary bypass. In: Tinker J, ed. Cardiopulmonary bypass: current concepts and controversies. Monograph. Philadelphia, PA: WB Saunders, 1989: 131-46.
2. Svennevig JL, Geiran OR, Karisen H et al. Complement activation during extracorporeal circulation. J Thorac Cardiovasc Surg 1993; 106: 466-72.
3. Baksaas ST, Videm V, Mollnes TE et al. Effects on complement, granulocytes and platelets of a leukocyte depletion filter during in vitro extracorporeal circulation. Scand Cardiovasc J 1997; 31: 73-78.
4. Gourlay T, Fleming J, Taylor KM. Laboratory evaluation of the Pall LG6 leucocyte-depleting arterial line filter. Perfusion 1992; 7: 131-40.
5. Thurlow PJ, Doolan L, Sharp R, Sullivan M, Smith B, Andersen LW. Laboratory studies of the effect of Pall extracorporeal leucocyte filters LG6 and AV6 on patients undergoing coronary bypass grafts. Perfusion 1996; 11: 29-37.
6. Mihaljevic T, Tønz M, von Segesser LK et al. The influence of leucocyte filtration during cardiopulmonary bypass on postoperative lung function. J Thorac Cardiovasc Surg 1995; 109: 1138-45.
7. Palanzo DA, Manley NJ, Montesano RN, Yeisley GL, Gordon D. Clinical evaluation of the LeukoGuard (LG6) arterial line filter for routine open heart surgery. Perfusion 1993; 8: 489-96.
8. Garred P, Mollnes TE, Lea T. Quantification in enzyme-linked immunosorbent assay of a C3 neoepitope expressed on activated human complement factor C3. Scand J Immunol 1988; 27: 329-35.
9. Mollnes TE, Lea T, Frøland SS, Harboe M. Quantification of the terminal complement complex in human plasma by an enzyme-linked immunosorbent assay based on monoclonal antibodies against a neoantigen of the complex. Scand J Immunol 1985; 22: 197-202.
10. Faymonville MEE, Pincemail J, Duchateau J et al. Myeloperoxidase and elastase as markers of leukocyte activation during cardiopulmonary bypass in humans. J Thorac Cardiovasc Surg 1992; 102: 309-17.
11. Osanna PJ, Test ST, Matheson NR et al. Oxidative regulation of neutrophil elastase-alpha-1-proteinase inhibitor interactions. J Clin Invest 1986; 77: 1939-44.
12. Rossen RD, Swain JL, Michael LJ, Weakley S, Giannini E, Entman ML. Selective accumulation of the first component of complement and leukocytes in ischemic canine heart muscle: a possible indicator of an extra myocardial mechanism of ischemic injury. Circ Res 1985; 57: 119-30.
13. Wedmore CV, Williams TJ. Control of vascular permeability by polymorphonuclear leukocytes in inflammation. Nature 1981; 289: 646-50.
14. Fantone HC, Ward PA. Role of oxygen-derived free radicals and metabolites in leukocyte-dependent inflammatory reactions. Am J Pathol 1982; 107: 397-418.
15. Suzuki M, Inauen W, Kvietys PR et al. Superoxide mediates reperfusion-induced leukocyte-endothelial cell interactions. Am J Physiol 1989; 257: H1740-45.
16. Kilgore KS, Shen JP, Miller BF et al. Enhancement by complement membrane attack complex of tumor necrosis factor induced endothelial cell expression of E-selectin and ICAM-1. J Immunol 1995; 155: 1434-41.
17. Chenoweth DE, Cooper SW, Hugli TE et al. Complement activation during cardiopulmonary bypass: evidence for generation of C3a and C5a anaphylatoxins. N Engl J Med 1981; 304: 497-503.
18. Boyle EM, Pohlman TH, Johnson MC, Verrier ED. The systemic inflammatory response. Ann Thorac Surg 1997; 64: 31-37.
19. Jansen NJG, van Oeveren W, van den Broek L et al. Inhibition by dexamethason of the reperfusion phenomena in cardiopulmonary bypass. J Thorac Cardiovasc Surg 1991; 102: 515-25.
20. Johnson D, Thomson D, Hurst T et al. Neutrophil-mediated acute lung injury after extracorporeal perfusion. J Thorac Cardiovasc Surg 1994; 107: 1193-202.
21. Schmidt FE, MacDonald MJ, Murphy CO et al. Leukocyte depletion of blood cardioplegia attenuates reperfusion injury. Ann Thorac Surg 1996; 62: 1691-97.
22. Byrne JG, Appleyard RF, Chin Lee C et al. Controlled reperfusion of the regionally ischemic myocardium with leukocyte-depleted blood reduces stunning, the no-reflow phenomenon, and infarct size. J Thorac Cardiovasc Surg 1992; 103: 66-72.
23. Cremer J, Martin M, Redl H et al. Systemic inflammatory response syndrome after cardiac operations. Ann Thorac Surg 1996; 61: 1714-29.
24. Pearl JM, Drinkwater DC, Laks H, Capouya ER, Gates RN. Leukocyte-depleted reperfusion of transplanted human hearts: a randomized, double-blind clinical trial. J Heart Lung Transplant 1992; 11: 1082-92.
25. Bando K, Pillai R, Cameron DE et al. Leukocyte depletion ameliorates free radical-mediated lung injury after cardiopulmonary bypass. J Thorac Cardiovasc Surg 1990; 99: 873-77.
26. Pillai R, Bando K. Schueler S, Zebley M, Reitz BA, Baumgartner A. Leukocyte depletion results in excellent heart-lung function after 12 hours of storage. Ann Thorac Surg 1990; 50: 211-14.
27. Gu YJ, de Vries AJ, Boonstra PW, van Oeveren W. Leukocyte depletion results in improved lung function and reduced inflammatory response after cardiac surgery. J Thorac Cardiovasc Surg 1996; 12: 494-500.