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Volumn 92, Issue 4, 2005, Pages 360-372

Angiogenesis and anti-angiogenic strategies for glioblastomas;Angiogenèse et stratégies anti-angiogéniques des glioblastomes

Author keywords

Angiogenesis; Antiangiogenic therapies; Clinical trial; Glioblastoma

Indexed keywords

2,4 DIMETHYL 5 (2 OXO 1H INDOL 3 YLMETHYLENE) 3 PYRROLEPROPIONIC ACID; ALPHA INTERFERON; ANGIOGENESIS INHIBITOR; ANGIOGENIC FACTOR; ANGIOSTATIN; ANTISENSE OLIGONUCLEOTIDE; BETA INTERFERON; CARBOPLATIN; CARMUSTINE; CELL ADHESION MOLECULE; CILENGITIDE; CISPLATIN; ENDOSTATIN; ETOPOSIDE; FIBROBLAST GROWTH FACTOR RECEPTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 2; FUMAGILLOL CHLOROACETYLCARBAMATE; IBUPROFEN; MARIMASTAT; METALLOPROTEINASE; MINOCYCLINE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY DC101; MONOCLONAL ANTIBODY LM 609; N (4 BROMO 2 FLUOROPHENYL) 6 METHOXY 7 [2 (1H 1,2,3 TRIAZOL 1 YL)ETHOXY] 4 QUINAZOLINAMINE; PLASMINOGEN KRINGLE 1 PROTEIN; PLASMINOGEN KRINGLE 2 PROTEIN; PLASMINOGEN KRINGLE 3 PROTEIN; POLYCLONAL ANTIBODY; PROTEIN KINASE C INHIBITOR; RECEPTOR; RECEPTOR BLOCKING AGENT; RIBOZYME; SCATTER FACTOR; SEMAXANIB; SMALL NUCLEAR RNA; SQUALAMINE; SUNITINIB; SURAMIN; TEMOZOLOMIDE; THALIDOMIDE; THROMBOCYTE FACTOR 4; THROMBOSPONDIN; TUMOR NECROSIS FACTOR ALPHA; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG; UROKINASE; VASCULOTROPIN ANTIBODY; VITRONECTIN RECEPTOR;

EID: 18344388517     PISSN: 00074551     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (15)

References (153)
  • 1
    • 0030952289 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis
    • Risau W. Mechanisms of angiogenesis. Nature 1997; 386: 671-4.
    • (1997) Nature , vol.386 , pp. 671-674
    • Risau, W.1
  • 2
    • 0013943005 scopus 로고
    • Tumor behavior in isolated perfused organs: In vitro growth and metastases of biopsy material in rabbit thyroid and canine intestinal segment
    • Folkman J, Cole P, Zimmerman S. Tumor behavior in isolated perfused organs: in vitro growth and metastases of biopsy material in rabbit thyroid and canine intestinal segment. Ann Surg 1966; 164: 491-502.
    • (1966) Ann Surg , vol.164 , pp. 491-502
    • Folkman, J.1    Cole, P.2    Zimmerman, S.3
  • 3
    • 0015380016 scopus 로고
    • Tumor dormancy in vivo by prevention of neovascularization
    • Gimbrone MJ, Leapman S, Cotran R, Folkman J. Tumor dormancy in vivo by prevention of neovascularization. J Exp Med 1972; 136: 261-76.
    • (1972) J Exp Med , vol.136 , pp. 261-276
    • Gimbrone, M.J.1    Leapman, S.2    Cotran, R.3    Folkman, J.4
  • 4
    • 0035160312 scopus 로고    scopus 로고
    • Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth
    • Lyden D, Hattori K, Dias S, Costa C, Blaikie P, Butros L, et al. Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nat Med 2001; 7: 1194-201.
    • (2001) Nat Med , vol.7 , pp. 1194-1201
    • Lyden, D.1    Hattori, K.2    Dias, S.3    Costa, C.4    Blaikie, P.5    Butros, L.6
  • 6
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan D, Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996; 86: 353-64.
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 7
    • 0030059969 scopus 로고    scopus 로고
    • Microvessel density is a prognostic indicator for patients with astroglial brain tumors
    • Leon S, Folkerrh R, Black P. Microvessel density is a prognostic indicator for patients with astroglial brain tumors. Cancer 1996; 77: 362-72.
    • (1996) Cancer , vol.77 , pp. 362-372
    • Leon, S.1    Folkerrh, R.2    Black, P.3
  • 9
    • 0029397222 scopus 로고
    • Angiogenesis in malignant gliomas
    • Plate K, Risau W. Angiogenesis in malignant gliomas. Glia 1995; 15: 339-47.
    • (1995) Glia , vol.15 , pp. 339-347
    • Plate, K.1    Risau, W.2
  • 10
    • 0034470379 scopus 로고    scopus 로고
    • Vascular microenvironment in gliomas
    • Vajkoczy P, Menger MD. Vascular microenvironment in gliomas. J Neurooncol 2000; 50: 99-108.
    • (2000) J Neurooncol , vol.50 , pp. 99-108
    • Vajkoczy, P.1    Menger, M.D.2
  • 11
    • 0026485002 scopus 로고
    • Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
    • Shweiki D, Itin A, Soffer D, Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 1992; 359: 843-5.
    • (1992) Nature , vol.359 , pp. 843-845
    • Shweiki, D.1    Itin, A.2    Soffer, D.3    Keshet, E.4
  • 12
    • 0028147863 scopus 로고
    • Hypoxic stimulation of vascular endothelial growth factor expression in vitro and in vivo
    • Minchenko A, Bauer T, Salceda S, Caro J. Hypoxic stimulation of vascular endothelial growth factor expression in vitro and in vivo. Lab Invest 1994; 71: 374-9.
    • (1994) Lab Invest , vol.71 , pp. 374-379
    • Minchenko, A.1    Bauer, T.2    Salceda, S.3    Caro, J.4
  • 13
    • 0026446102 scopus 로고
    • Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
    • Plate K, Breier G, Weich H, Risau W. Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature 1992; 359: 845-8.
    • (1992) Nature , vol.359 , pp. 845-848
    • Plate, K.1    Breier, G.2    Weich, H.3    Risau, W.4
  • 14
    • 0029117223 scopus 로고
    • Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells
    • Ikeda E, Achen M, Breier G, Risau W. Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells. J Biol Chem 1995; 270: 19761-6.
    • (1995) J Biol Chem , vol.270 , pp. 19761-19766
    • Ikeda, E.1    Achen, M.2    Breier, G.3    Risau, W.4
  • 15
    • 0034213146 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor 1alpha in brain tumors: Association with angiogenesis, invasion, and progression
    • Zagzag D, Zhong H, Scalzirti J, Laughner E, Simons J, Semenza G. Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression. Cancer 2000; 88: 2606-18.
    • (2000) Cancer , vol.88 , pp. 2606-2618
    • Zagzag, D.1    Zhong, H.2    Scalzirti, J.3    Laughner, E.4    Simons, J.5    Semenza, G.6
  • 16
    • 0033047875 scopus 로고    scopus 로고
    • VEGFs, receptors and angiogenesis
    • Veikkola T, Alitalo K. VEGFs, receptors and angiogenesis. Semin Cancer Biol 1999; 9: 211-20.
    • (1999) Semin Cancer Biol , vol.9 , pp. 211-220
    • Veikkola, T.1    Alitalo, K.2
  • 17
    • 0027412319 scopus 로고
    • Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: A model of glioblastoma multiforme pathophysiology
    • Goldman CK, Kim J, Wong WL, King V, Brock T, Gillespie GY. Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: a model of glioblastoma multiforme pathophysiology. Mol Biol Cell 1993; 4: 121-33.
    • (1993) Mol Biol Cell , vol.4 , pp. 121-133
    • Goldman, C.K.1    Kim, J.2    Wong, W.L.3    King, V.4    Brock, T.5    Gillespie, G.Y.6
  • 18
    • 0032825703 scopus 로고    scopus 로고
    • Differential control of VEGF synthesis and secretion in human glioma cells by IL-1 and EGF
    • Valter M, Wiestler O, Pietsch T. Differential control of VEGF synthesis and secretion in human glioma cells by IL-1 and EGF. Int J Dev Neurosc 1999; 17: 565-77.
    • (1999) Int J Dev Neurosc , vol.17 , pp. 565-577
    • Valter, M.1    Wiestler, O.2    Pietsch, T.3
  • 19
    • 0032504607 scopus 로고    scopus 로고
    • Up-regulation of vascular endothelial growth factor induced by hepatocyte growth factor/scatter factor stimulation in human glioma cells
    • Moriyama T, Kataoka H, Hamasuna R, Yokogami K, Uehara H, Kawano H, et al. Up-regulation of vascular endothelial growth factor induced by hepatocyte growth factor/scatter factor stimulation in human glioma cells. Biochem Biophys Res Commun 1998; 249: 73-7.
    • (1998) Biochem Biophys Res Commun , vol.249 , pp. 73-77
    • Moriyama, T.1    Kataoka, H.2    Hamasuna, R.3    Yokogami, K.4    Uehara, H.5    Kawano, H.6
  • 20
    • 0028060380 scopus 로고
    • Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1
    • Dameron K, Volpert O, Tainsky M, Bouck N. Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1. Science 1994; 265: 1582-4.
    • (1994) Science , vol.265 , pp. 1582-1584
    • Dameron, K.1    Volpert, O.2    Tainsky, M.3    Bouck, N.4
  • 22
    • 0030722076 scopus 로고    scopus 로고
    • Non-small-cell lung carcinoma tumor growth without morphological evidence of neo-angiogenesis
    • Pezzella F, Pastorino U, Tagliabue E, Andreola S, Sozzi G, Gasparini G, et al. Non-small-cell lung carcinoma tumor growth without morphological evidence of neo-angiogenesis. Am J Pathol 1997; 151: 1417-23.
    • (1997) Am J Pathol , vol.151 , pp. 1417-1423
    • Pezzella, F.1    Pastorino, U.2    Tagliabue, E.3    Andreola, S.4    Sozzi, G.5    Gasparini, G.6
  • 23
    • 0033580889 scopus 로고    scopus 로고
    • Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF
    • Holash J, Maisonpierre P, Compton D, Boland P, Alexander C, Zagzag D, et al. Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF. Science 1999; 284: 1994-8.
    • (1999) Science , vol.284 , pp. 1994-1998
    • Holash, J.1    Maisonpierre, P.2    Compton, D.3    Boland, P.4    Alexander, C.5    Zagzag, D.6
  • 24
    • 0033917495 scopus 로고    scopus 로고
    • Vascular apoptosis and involution in gliomas precede neovascularization: A novel concept for glioma growth and angiogenesis
    • Zagzag D, Amirnovin R, Greco M, Yee H, Holash J, Wiegand S, et al. Vascular apoptosis and involution in gliomas precede neovascularization: a novel concept for glioma growth and angiogenesis. Lab Invest 2000; 80: 837-49.
    • (2000) Lab Invest , vol.80 , pp. 837-849
    • Zagzag, D.1    Amirnovin, R.2    Greco, M.3    Yee, H.4    Holash, J.5    Wiegand, S.6
  • 25
    • 0036780251 scopus 로고    scopus 로고
    • Clinical translation of angiogenesis inhibitors
    • Kerbel R, Folkman J. Clinical translation of angiogenesis inhibitors. Nat Rev Cancer 2002; 2: 727-39.
    • (2002) Nat Rev Cancer , vol.2 , pp. 727-739
    • Kerbel, R.1    Folkman, J.2
  • 26
    • 0035884609 scopus 로고    scopus 로고
    • Inhibition of glioma angiogenesis and growth in vivo by systemic treatment with a monoclonal antibody against vascular endothelial growth factor receptor-2
    • Kunkel P, Ulbricht U, Bohlen P, Brockmann MA, Fillbrandt R, Stavrou D, et al. Inhibition of glioma angiogenesis and growth in vivo by systemic treatment with a monoclonal antibody against vascular endothelial growth factor receptor-2. Cancer Res 2001; 61: 6624-8.
    • (2001) Cancer Res , vol.61 , pp. 6624-6628
    • Kunkel, P.1    Ulbricht, U.2    Bohlen, P.3    Brockmann, M.A.4    Fillbrandt, R.5    Stavrou, D.6
  • 27
    • 0033822622 scopus 로고    scopus 로고
    • Anti-VEGF antibody treatment of glioblastoma prolongs survival but results in increased vascular cooption
    • Rubenstein JL, Kim J, Ozawa T, Zhang M, Westphal M, Deen DF, et al. Anti-VEGF antibody treatment of glioblastoma prolongs survival but results in increased vascular cooption. Neoplasia 2000; 2: 306-14.
    • (2000) Neoplasia , vol.2 , pp. 306-314
    • Rubenstein, J.L.1    Kim, J.2    Ozawa, T.3    Zhang, M.4    Westphal, M.5    Deen, D.F.6
  • 28
    • 0042966942 scopus 로고    scopus 로고
    • A novel approach to glioma gene therapy: Down-regulation of the vascular endothelial growth factor in glioma cells using ribozymes
    • Ke L, Fueyo J, Chen X, Steck P, Shi Y, Im S, et al. A novel approach to glioma gene therapy: down-regulation of the vascular endothelial growth factor in glioma cells using ribozymes. Int J Oncol 1998; 12: 1391-6.
    • (1998) Int J Oncol , vol.12 , pp. 1391-1396
    • Ke, L.1    Fueyo, J.2    Chen, X.3    Steck, P.4    Shi, Y.5    Im, S.6
  • 29
    • 0030029271 scopus 로고    scopus 로고
    • Inhibition of growth of C6 glioma cells in vivo by expression of antisens vascular endothelial growth factor sequence
    • Saleh M, Stacker SA, Wilks AF. Inhibition of growth of C6 glioma cells in vivo by expression of antisens vascular endothelial growth factor sequence. Cancer Res 1996; 56: 393-401.
    • (1996) Cancer Res , vol.56 , pp. 393-401
    • Saleh, M.1    Stacker, S.A.2    Wilks, A.F.3
  • 30
    • 0032417924 scopus 로고    scopus 로고
    • Modulation of angiogenesis by human glioma xenograft models that differentially express vascular endothelial growth factor
    • Ma J, Fei ZL, Klein-Szanto A, Gallo JM. Modulation of angiogenesis by human glioma xenograft models that differentially express vascular endothelial growth factor. Clin Exp Metastasis 1998; 16: 559-68.
    • (1998) Clin Exp Metastasis , vol.16 , pp. 559-568
    • Ma, J.1    Fei, Z.L.2    Klein-Szanto, A.3    Gallo, J.M.4
  • 31
    • 0033557535 scopus 로고    scopus 로고
    • Antiangiogenesis treatment for gliomas: Transfer of antisens-vascular endothelial growth factor inhibits tumor growth in vivo
    • Im SA, Gomez-Manzano C, Fueyo J, Liu TJ, Ke LD, Kim JS, et al. Antiangiogenesis treatment for gliomas: transfer of antisens-vascular endothelial growth factor inhibits tumor growth in vivo. Cancer Res 1999; 59: 895-900.
    • (1999) Cancer Res , vol.59 , pp. 895-900
    • Im, S.A.1    Gomez-Manzano, C.2    Fueyo, J.3    Liu, T.J.4    Ke, L.D.5    Kim, J.S.6
  • 32
    • 0029782859 scopus 로고    scopus 로고
    • Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor
    • Cheng S, Huang H, Nagane M, Ji X, Wang D, Shih C, et al. Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor. Proc Natl Acad Sci USA 1996; 93: 8502-7.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 8502-8507
    • Cheng, S.1    Huang, H.2    Nagane, M.3    Ji, X.4    Wang, D.5    Shih, C.6
  • 33
    • 0032846624 scopus 로고    scopus 로고
    • Retrovirus producer cells encoding antisense VEGF prolong survival of rats with intracranial GS9L gliomas
    • Sasaki M, Wizigmann-Voos S, Risau W, Plare KH. Retrovirus producer cells encoding antisense VEGF prolong survival of rats with intracranial GS9L gliomas. Int J Dev Neurosci 1999; 17: 579-91.
    • (1999) Int J Dev Neurosci , vol.17 , pp. 579-591
    • Sasaki, M.1    Wizigmann-Voos, S.2    Risau, W.3    Plare, K.H.4
  • 34
    • 0032804144 scopus 로고    scopus 로고
    • Suramin treatment of human glioma xenografts; effects on tumor vasculature and oxygenation status
    • Bernsen H, Rijken P, Peters J, Bakker J, Boerman R, Wesseling P, et al. Suramin treatment of human glioma xenografts; effects on tumor vasculature and oxygenation status. J Neurooncol 1998; 44: 129-36.
    • (1998) J Neurooncol , vol.44 , pp. 129-136
    • Bernsen, H.1    Rijken, P.2    Peters, J.3    Bakker, J.4    Boerman, R.5    Wesseling, P.6
  • 35
    • 0032893263 scopus 로고    scopus 로고
    • SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types
    • Fong T, Shawver L, Sun L, Tang C, App H, Powell T, et al. SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types. Cancer Res 1999; 59: 99-106.
    • (1999) Cancer Res , vol.59 , pp. 99-106
    • Fong, T.1    Shawver, L.2    Sun, L.3    Tang, C.4    App, H.5    Powell, T.6
  • 36
    • 0035700915 scopus 로고    scopus 로고
    • Flk-1 specific kinase inhibitor (SU5416) inhibited the growth of GS-9L glioma in rat brain and prolonged the survival
    • Takamoto T, Sasaki M, Kuno T, Tamaki N. Flk-1 specific kinase inhibitor (SU5416) inhibited the growth of GS-9L glioma in rat brain and prolonged the survival. Kobe J Med Sci 2001; 47: 181-91.
    • (2001) Kobe J Med Sci , vol.47 , pp. 181-191
    • Takamoto, T.1    Sasaki, M.2    Kuno, T.3    Tamaki, N.4
  • 37
    • 0033107767 scopus 로고    scopus 로고
    • Inhibition of tumor growth, angiogenesis, and microcirculation by the novel Flk-1 inhibitor SU5416 as assessed by intravital multifluorescence videomicroscopy
    • Vajkoczy P, Menger MD, Vollmar B, Schilling L, Schmiedek P, Hirth KP, et al. Inhibition of tumor growth, angiogenesis, and microcirculation by the novel Flk-1 inhibitor SU5416 as assessed by intravital multifluorescence videomicroscopy. Neoplasia 1999; 1: 31-41.
    • (1999) Neoplasia , vol.1 , pp. 31-41
    • Vajkoczy, P.1    Menger, M.D.2    Vollmar, B.3    Schilling, L.4    Schmiedek, P.5    Hirth, K.P.6
  • 38
    • 0034652716 scopus 로고    scopus 로고
    • ZD4190: An orally active inhibitor of vascular endothelial growth factor signaling with broad-spectrum antitumor efficacy
    • Wedge SR, Ogilvie DJ, Dukes M, Kendrew J, Curwen JO, Hennequin LF, et al. ZD4190: an orally active inhibitor of vascular endothelial growth factor signaling with broad-spectrum antitumor efficacy. Cancer Res 2000; 60: 970-5.
    • (2000) Cancer Res , vol.60 , pp. 970-975
    • Wedge, S.R.1    Ogilvie, D.J.2    Dukes, M.3    Kendrew, J.4    Curwen, J.O.5    Hennequin, L.F.6
  • 39
    • 0033883776 scopus 로고    scopus 로고
    • SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors
    • Laird A, Vajkoczy P, Shawver L, Thurnher A, Liang C, Mohammadi M, et al. SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors. Cancer Res 2000; 60: 4152-60.
    • (2000) Cancer Res , vol.60 , pp. 4152-4160
    • Laird, A.1    Vajkoczy, P.2    Shawver, L.3    Thurnher, A.4    Liang, C.5    Mohammadi, M.6
  • 40
    • 0027970092 scopus 로고
    • Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
    • O'Reilly M, Holmgren L, Shing Y, Chen C, Rosenthal R, Moses M, et al. Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 1994; 79: 315-28.
    • (1994) Cell , vol.79 , pp. 315-328
    • O'Reilly, M.1    Holmgren, L.2    Shing, Y.3    Chen, C.4    Rosenthal, R.5    Moses, M.6
  • 41
    • 0032832479 scopus 로고    scopus 로고
    • Regulation of angiostatin production by matrix metalloproteinase-2 in a model of concomitant resistance
    • O'Reilly MS, Wiederschain D, Stetler-Stevenson WG, Folkman J, Moses MA. Regulation of angiostatin production by matrix metalloproteinase-2 in a model of concomitant resistance. J Biol Chem 1999; 274: 29568-71.
    • (1999) J Biol Chem , vol.274 , pp. 29568-29571
    • O'Reilly, M.S.1    Wiederschain, D.2    Stetler-Stevenson, W.G.3    Folkman, J.4    Moses, M.A.5
  • 43
    • 0033609691 scopus 로고    scopus 로고
    • Inhibition of human malignant glioma growth in vivo by human recombinant plasminogen kringles 1-3
    • Joe YA, Hong YK, Chung DS, Yang YJ, Kang JK, Lee YS, et al. Inhibition of human malignant glioma growth in vivo by human recombinant plasminogen kringles 1-3. Int J Cancer 1999; 82: 694-9.
    • (1999) Int J Cancer , vol.82 , pp. 694-699
    • Joe, Y.A.1    Hong, Y.K.2    Chung, D.S.3    Yang, Y.J.4    Kang, J.K.5    Lee, Y.S.6
  • 44
    • 0032713943 scopus 로고    scopus 로고
    • Simplified production of a recombinant human angiostatin derivative that suppresses intracerebral glial tumor growth
    • Meneses PI, Abrey LE, Hajjar KA, Gultekin SH, Duvoisin RM, Berns KI, et al. Simplified production of a recombinant human angiostatin derivative that suppresses intracerebral glial tumor growth. Clin Cancer Res 1999; 5: 3689-94.
    • (1999) Clin Cancer Res , vol.5 , pp. 3689-3694
    • Meneses, P.I.1    Abrey, L.E.2    Hajjar, K.A.3    Gultekin, S.H.4    Duvoisin, R.M.5    Berns, K.I.6
  • 45
    • 0029944122 scopus 로고    scopus 로고
    • Angiostatin induces and sustains dormancy of human primary tumors in mice
    • O'Reilly M, Holmgren L, Chen C, Folkman J. Angiostatin induces and sustains dormancy of human primary tumors in mice. Nat Med 1996; 2: 689-92.
    • (1996) Nat Med , vol.2 , pp. 689-692
    • O'Reilly, M.1    Holmgren, L.2    Chen, C.3    Folkman, J.4
  • 46
    • 0035810936 scopus 로고    scopus 로고
    • Endothelial cell surface F1-F0 ATP synthase is active in ATP synthesis and is inhibited by angiostatin
    • Moser TL, Kenan DJ, Ashley TA, Roy JA, Goodman MD, Misra UK, et al. Endothelial cell surface F1-F0 ATP synthase is active in ATP synthesis and is inhibited by angiostatin. Proc Natl Acad Sci USA 2001; 98: 6656-61.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6656-6661
    • Moser, T.L.1    Kenan, D.J.2    Ashley, T.A.3    Roy, J.A.4    Goodman, M.D.5    Misra, U.K.6
  • 47
    • 0031029458 scopus 로고    scopus 로고
    • Endothelial hypoxic stress proteins
    • Graven KK, Farber HW. Endothelial hypoxic stress proteins. Kidney Int 1997; 51: 426-37.
    • (1997) Kidney Int , vol.51 , pp. 426-437
    • Graven, K.K.1    Farber, H.W.2
  • 48
    • 0035955645 scopus 로고    scopus 로고
    • Specific interaction of angiostatin with integrin alpha(v)beta(3) in endothelial cells
    • Tarui T, Miles LA, Takada Y. Specific interaction of angiostatin with integrin alpha(v)beta(3) in endothelial cells. J Biol Chem 2001; 276: 39562-8.
    • (2001) J Biol Chem , vol.276 , pp. 39562-39568
    • Tarui, T.1    Miles, L.A.2    Takada, Y.3
  • 49
    • 0034910635 scopus 로고    scopus 로고
    • Growth of human melanoma xenografts is suppressed by systemic angiostatin gene therapy
    • Rodolfo M, Cato EM, Soldari S, Ceruti R, Asioli M, Scanziani E, et al. Growth of human melanoma xenografts is suppressed by systemic angiostatin gene therapy. Cancer Gene Ther 2001; 8: 491-6.
    • (2001) Cancer Gene Ther , vol.8 , pp. 491-496
    • Rodolfo, M.1    Cato, E.M.2    Soldari, S.3    Ceruti, R.4    Asioli, M.5    Scanziani, E.6
  • 50
    • 0035878870 scopus 로고    scopus 로고
    • Effects of angiostatin gene transfer on functional properties and in vivo growth of Kaposi's sarcoma cells
    • Indraccolo S, Morini M, Gola E, Carrozzino F, Habeler W, Minghelli S, et al. Effects of angiostatin gene transfer on functional properties and in vivo growth of Kaposi's sarcoma cells. Cancer Res 2001; 61: 5441-6.
    • (2001) Cancer Res , vol.61 , pp. 5441-5446
    • Indraccolo, S.1    Morini, M.2    Gola, E.3    Carrozzino, F.4    Habeler, W.5    Minghelli, S.6
  • 51
    • 0034858028 scopus 로고    scopus 로고
    • Adenoviral vector expressing murine angiostatin inhibits a model of breast cancer metastatic growth in the lungs of mice
    • Gyorffy S, Palmer K, Gauldie J. Adenoviral vector expressing murine angiostatin inhibits a model of breast cancer metastatic growth in the lungs of mice. Am J Pathol 2001; 159: 1137-47.
    • (2001) Am J Pathol , vol.159 , pp. 1137-1147
    • Gyorffy, S.1    Palmer, K.2    Gauldie, J.3
  • 52
    • 0037942860 scopus 로고    scopus 로고
    • Antiangiogenic therapy against experimental glioblastoma using genetically engineered cells producing interferon-alpha, angiostatin, or endostatin
    • De Bouard S, Guillamo JS, Christov C, Lefevre N, Brugieres P, Gola E, et al. Antiangiogenic therapy against experimental glioblastoma using genetically engineered cells producing interferon-alpha, angiostatin, or endostatin. Hum Gene Ther 2003; 14: 883-95.
    • (2003) Hum Gene Ther , vol.14 , pp. 883-895
    • De Bouard, S.1    Guillamo, J.S.2    Christov, C.3    Lefevre, N.4    Brugieres, P.5    Gola, E.6
  • 53
  • 54
    • 0036289066 scopus 로고    scopus 로고
    • Differential effects of angiostatin, endostatin and interferon-alpha(1) gene transfer on in vivo growth of human breast cancer cells
    • Indraccolo S, Gola E, Rosato A, Minuzzo S, Habeler W, Tisato V, et al. Differential effects of angiostatin, endostatin and interferon-alpha(1) gene transfer on in vivo growth of human breast cancer cells. Gene Ther 2002; 9: 867-78.
    • (2002) Gene Ther , vol.9 , pp. 867-878
    • Indraccolo, S.1    Gola, E.2    Rosato, A.3    Minuzzo, S.4    Habeler, W.5    Tisato, V.6
  • 55
    • 0031454617 scopus 로고    scopus 로고
    • Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
    • O'Reilly M, Boehm T, Shing Y, Fukai N, Vasios G, Lane W, et al. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell 1997; 88: 277-85.
    • (1997) Cell , vol.88 , pp. 277-285
    • O'Reilly, M.1    Boehm, T.2    Shing, Y.3    Fukai, N.4    Vasios, G.5    Lane, W.6
  • 56
    • 0031469819 scopus 로고    scopus 로고
    • Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance
    • Boehm T, Folkman J, Browder T, O'Reilly M. Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance. Nature 1997; 390: 404-7.
    • (1997) Nature , vol.390 , pp. 404-407
    • Boehm, T.1    Folkman, J.2    Browder, T.3    O'Reilly, M.4
  • 58
    • 0035838722 scopus 로고    scopus 로고
    • Research of cloning, expression of human endostatin gene and its inhibition effects to the glioma in vivo
    • Zhang X, Wu J, Fei Z. Research of cloning, expression of human endostatin gene and its inhibition effects to the glioma in vivo. Zhonghua Yi Xue Za Zhi 2001; 81: 783-7.
    • (2001) Zhonghua Yi Xue Za Zhi , vol.81 , pp. 783-787
    • Zhang, X.1    Wu, J.2    Fei, Z.3
  • 59
    • 0035172407 scopus 로고    scopus 로고
    • Continuous release of endostatin from microencapsulated engineered cells for tumor therapy
    • Joki T, Machluf M, Atala A, Zhu J, Seyfried NT, Dunn IF, et al. Continuous release of endostatin from microencapsulated engineered cells for tumor therapy. Nat Biotechnol 2001; 19: 35-9.
    • (2001) Nat Biotechnol , vol.19 , pp. 35-39
    • Joki, T.1    Machluf, M.2    Atala, A.3    Zhu, J.4    Seyfried, N.T.5    Dunn, I.F.6
  • 61
    • 0029754648 scopus 로고    scopus 로고
    • Inhibition of angiogenesis in human glioblastomas by chromosome 10 induction of thrombospondin-1
    • Hsu S, Volpert O, Steck P, Mikkelsen T, Polverini P, Rao S, et al. Inhibition of angiogenesis in human glioblastomas by chromosome 10 induction of thrombospondin-1. Cancer Res 1996; 56: 5684-91.
    • (1996) Cancer Res , vol.56 , pp. 5684-5691
    • Hsu, S.1    Volpert, O.2    Steck, P.3    Mikkelsen, T.4    Polverini, P.5    Rao, S.6
  • 62
    • 0025853349 scopus 로고
    • Thrombospondin exerts an anti-angiogenic effect on cord formation by endothelial cells in vitro
    • Iruela-Arispe M, Bornstein P, Sage H. Thrombospondin exerts an anti-angiogenic effect on cord formation by endothelial cells in vitro. Proc Natl Acad Sci USA 1991; 88: 5026-30.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 5026-5030
    • Iruela-Arispe, M.1    Bornstein, P.2    Sage, H.3
  • 63
    • 0036104828 scopus 로고    scopus 로고
    • Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor
    • Volpert OV, Zaichuk T, Zhou W, Reiher F, Ferguson TA, Stuart PM, et al. Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor. Nat Med 2002; 8: 349-57.
    • (2002) Nat Med , vol.8 , pp. 349-357
    • Volpert, O.V.1    Zaichuk, T.2    Zhou, W.3    Reiher, F.4    Ferguson, T.A.5    Stuart, P.M.6
  • 64
    • 0029347102 scopus 로고
    • Diversity of function is inherent in matricellular proteins: An appraisal of thrombospondin 1
    • Bornstein P. Diversity of function is inherent in matricellular proteins: an appraisal of thrombospondin 1. J Cell Biol 1995; 1995: 503-6.
    • (1995) J Cell Biol , vol.1995 , pp. 503-506
    • Bornstein, P.1
  • 65
    • 0024333978 scopus 로고
    • Antitumor effects of interferon
    • Gresser I. Antitumor effects of interferon. Acta Oncol 1989; 28: 347-53.
    • (1989) Acta Oncol , vol.28 , pp. 347-353
    • Gresser, I.1
  • 66
    • 0032526030 scopus 로고    scopus 로고
    • Biological properties of recombinant alpha-interferons: 40th Anniversary of the discovery of interferons
    • Pfeffer LM, Dinarello CA, Herberman RB, Williams BR, Borden EC, Bordens R, et al. Biological properties of recombinant alpha-interferons: 40th anniversary of the discovery of interferons. Cancer Res 1998; 58: 2489-99.
    • (1998) Cancer Res , vol.58 , pp. 2489-2499
    • Pfeffer, L.M.1    Dinarello, C.A.2    Herberman, R.B.3    Williams, B.R.4    Borden, E.C.5    Bordens, R.6
  • 67
    • 0019306152 scopus 로고
    • Inhibition of cell motility by interferon
    • Brouty-Boye D, Zetter BR. Inhibition of cell motility by interferon. Science 1980; 208: 516-8.
    • (1980) Science , vol.208 , pp. 516-518
    • Brouty-Boye, D.1    Zetter, B.R.2
  • 68
    • 0032519590 scopus 로고    scopus 로고
    • Inhibition of basic fibroblast growth factor expression, angiogenesis, and growth of human bladder carcinoma in mice by systemic interferon-alpha administration
    • Dinney CP, Bielenberg DR, Perrotte P, Reich R, Eve BY, Bucana CD, et al. Inhibition of basic fibroblast growth factor expression, angiogenesis, and growth of human bladder carcinoma in mice by systemic interferon-alpha administration. Cancer Res 1998; 58: 808-14.
    • (1998) Cancer Res , vol.58 , pp. 808-814
    • Dinney, C.P.1    Bielenberg, D.R.2    Perrotte, P.3    Reich, R.4    Eve, B.Y.5    Bucana, C.D.6
  • 69
    • 0342614891 scopus 로고    scopus 로고
    • Expression of basic fibroblast growth factor protein and its down-regulation by interferons in head and neck cancer
    • Riedel F, Gotte K, Bergler W, Rojas W, Hormann K. Expression of basic fibroblast growth factor protein and its down-regulation by interferons in head and neck cancer. Head Neck 2000; 22: 183-9.
    • (2000) Head Neck , vol.22 , pp. 183-189
    • Riedel, F.1    Gotte, K.2    Bergler, W.3    Rojas, W.4    Hormann, K.5
  • 70
    • 0033848253 scopus 로고    scopus 로고
    • Inhibition of angiogenesis and vascular tumor growth by interferon-producing cells: A gene therapy approach
    • Albini A, Marchisone C, Del Grosso F, Benelli R, Masiello L, Tacchetti C, et al. Inhibition of angiogenesis and vascular tumor growth by interferon-producing cells: a gene therapy approach. Am J Pathol 2000; 156: 1381-93.
    • (2000) Am J Pathol , vol.156 , pp. 1381-1393
    • Albini, A.1    Marchisone, C.2    Del Grosso, F.3    Benelli, R.4    Masiello, L.5    Tacchetti, C.6
  • 71
    • 0020619315 scopus 로고
    • Antitumor effects of interferon in mice injected with interferon-sensitive and interferon-resistant Friend leukemia cells. III. Inhibition of growth and necrosis of tumors implanted subcutaneously
    • Belardelli F, Gresser I, Maury C, Duvillard P, Prade M, Maunouty MT. Antitumor effects of interferon in mice injected with interferon-sensitive and interferon-resistant Friend leukemia cells. III. Inhibition of growth and necrosis of tumors implanted subcutaneously. Int J Cancer 1983; 31: 649-53.
    • (1983) Int J Cancer , vol.31 , pp. 649-653
    • Belardelli, F.1    Gresser, I.2    Maury, C.3    Duvillard, P.4    Prade, M.5    Maunouty, M.T.6
  • 73
    • 0034740583 scopus 로고    scopus 로고
    • Interferon alpha2b gene delivery using adenoviral vector causes inhibition of tumor growth in xenograft models from a variety of cancers
    • Iqbal Ahmed CM, Johnson DE, Demers GW, Engler H, Howe JA, Wills KN, et al. Interferon alpha2b gene delivery using adenoviral vector causes inhibition of tumor growth in xenograft models from a variety of cancers. Cancer Gene Ther 2001; 8: 788-95.
    • (2001) Cancer Gene Ther , vol.8 , pp. 788-795
    • Iqbal Ahmed, C.M.1    Johnson, D.E.2    Demers, G.W.3    Engler, H.4    Howe, J.A.5    Wills, K.N.6
  • 74
    • 0031789663 scopus 로고    scopus 로고
    • The effect of interferon and anti-CD44 antibody on mouse glioma invasiveness in vitro
    • Wiranowska M, Tresser N, Saporta S. The effect of interferon and anti-CD44 antibody on mouse glioma invasiveness in vitro. Anticancer Res 1998; 18: 3331-8.
    • (1998) Anticancer Res , vol.18 , pp. 3331-3338
    • Wiranowska, M.1    Tresser, N.2    Saporta, S.3
  • 75
    • 0032127022 scopus 로고    scopus 로고
    • Interferon-alpha enhances CD95L-induced apoptosis of human malignant glioma cells
    • Roth W, Wagenknecht B, Dichgans J, Weller M. Interferon-alpha enhances CD95L-induced apoptosis of human malignant glioma cells. J Neuroimmunol 1998; 87: 121-9.
    • (1998) J Neuroimmunol , vol.87 , pp. 121-129
    • Roth, W.1    Wagenknecht, B.2    Dichgans, J.3    Weller, M.4
  • 76
    • 0036154887 scopus 로고    scopus 로고
    • Hemangioendothelioma: Successful therapy with interferon-alpha: A study in Association with the Italian Pediatric Haematology/Oncology Society (AIEOP)
    • Deb G, Donfrancesco A, Ilari I, De Sio L, Milano GM, Ghitti C, et al. Hemangioendothelioma: successful therapy with interferon-alpha: a study in Association with the Italian Pediatric Haematology/Oncology Society (AIEOP). Med Pediatr Oncol 2002; 38: 118-9.
    • (2002) Med Pediatr Oncol , vol.38 , pp. 118-119
    • Deb, G.1    Donfrancesco, A.2    Ilari, I.3    De Sio, L.4    Milano, G.M.5    Ghitti, C.6
  • 77
    • 0036482917 scopus 로고    scopus 로고
    • Successful antiangiogenic therapy of giant cell angioblastoma with interferon alfa 2b: Report of 2 cases
    • Marler JJ, Rubin JB, Trede NS, Connors S, Grier H, Upton J, et al. Successful antiangiogenic therapy of giant cell angioblastoma with interferon alfa 2b: report of 2 cases. Pediatrics 2002; 109: E37.
    • (2002) Pediatrics , vol.109
    • Marler, J.J.1    Rubin, J.B.2    Trede, N.S.3    Connors, S.4    Grier, H.5    Upton, J.6
  • 78
    • 0033041884 scopus 로고    scopus 로고
    • Antiangiogenic therapy of a recurrent giant cell tumor of the mandible with interferon alfa-2a
    • Kaban LB, Mulliken JB, Ezekowitz RA, Ebb D, Smith PS, Folkman J. Antiangiogenic therapy of a recurrent giant cell tumor of the mandible with interferon alfa-2a. Pediatrics 1999; 103: 1145-9.
    • (1999) Pediatrics , vol.103 , pp. 1145-1149
    • Kaban, L.B.1    Mulliken, J.B.2    Ezekowitz, R.A.3    Ebb, D.4    Smith, P.S.5    Folkman, J.6
  • 81
    • 0035878917 scopus 로고    scopus 로고
    • A phase III study of radiation therapy plus carmustine with or without recombinant interferon-alpha in the treatment of patients with newly diagnosed high-grade glioma
    • Buckner JC, Schomberg PJ, McGinnis WL, Cascino TL, Scheithauer BW, O'Fallon JR, et al. A phase III study of radiation therapy plus carmustine with or without recombinant interferon-alpha in the treatment of patients with newly diagnosed high-grade glioma. Cancer 2001; 92: 420-33.
    • (2001) Cancer , vol.92 , pp. 420-433
    • Buckner, J.C.1    Schomberg, P.J.2    McGinnis, W.L.3    Cascino, T.L.4    Scheithauer, B.W.5    O'Fallon, J.R.6
  • 83
    • 0025921602 scopus 로고
    • Persistent neurotoxicity of systemically administered inrerferon-alpha
    • Meyers CA, Scheibel RS, Forman AD. Persistent neurotoxicity of systemically administered inrerferon-alpha. Neurology 1991; 41: 672-6.
    • (1991) Neurology , vol.41 , pp. 672-676
    • Meyers, C.A.1    Scheibel, R.S.2    Forman, A.D.3
  • 84
    • 0022415830 scopus 로고
    • Phase I clinical trial of intralesional or intraventricular leukocyte interferon for intracranial malignancies
    • Obbens EA, Feun LG, Leavens ME, Savaraj N, Stewart DJ, Gutterman JU. Phase I clinical trial of intralesional or intraventricular leukocyte interferon for intracranial malignancies. J Neurooncol 1985; 3: 61-7.
    • (1985) J Neurooncol , vol.3 , pp. 61-67
    • Obbens, E.A.1    Feun, L.G.2    Leavens, M.E.3    Savaraj, N.4    Stewart, D.J.5    Gutterman, J.U.6
  • 85
    • 0030936629 scopus 로고    scopus 로고
    • Antibodies to interferon-alpha in treated cancer patients: Incidence and significance
    • McKenna RM, Oberg KE. Antibodies to interferon-alpha in treated cancer patients: incidence and significance. J Interferon Cytokine Res 1997; 17: 141-3.
    • (1997) J Interferon Cytokine Res , vol.17 , pp. 141-143
    • McKenna, R.M.1    Oberg, K.E.2
  • 86
    • 0029075603 scopus 로고
    • Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas
    • Singh RK, Gutman M, Bucana CD, Sanchez R, Llansa N, Fidler IJ. Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas. Proc Natl Acad Sci USA 1995; 92: 4562-6.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 4562-4566
    • Singh, R.K.1    Gutman, M.2    Bucana, C.D.3    Sanchez, R.4    Llansa, N.5    Fidler, I.J.6
  • 87
    • 0034904471 scopus 로고    scopus 로고
    • Adenovirus-mediated interferon-beta gene therapy suppresses growth and metastasis of human prostate cancer in nude mice
    • Cao G, Su J, Lu W, Zhang F, Zhao G, Marteralli D, et al. Adenovirus-mediated interferon-beta gene therapy suppresses growth and metastasis of human prostate cancer in nude mice. Cancer Gene Ther 2001; 8: 497-505.
    • (2001) Cancer Gene Ther , vol.8 , pp. 497-505
    • Cao, G.1    Su, J.2    Lu, W.3    Zhang, F.4    Zhao, G.5    Marteralli, D.6
  • 88
    • 0033902039 scopus 로고    scopus 로고
    • Efficient inhibition of in vivo human malignant glioma growth and angiogenesis by interferon-beta treatment at early stage of tumor development
    • Hong Y, Chung D, Joe Y, Yang Y, Kim K, Park Y, et al. Efficient inhibition of in vivo human malignant glioma growth and angiogenesis by interferon-beta treatment at early stage of tumor development. Clin Cancer Res 2000; 6: 3354-60.
    • (2000) Clin Cancer Res , vol.6 , pp. 3354-3360
    • Hong, Y.1    Chung, D.2    Joe, Y.3    Yang, Y.4    Kim, K.5    Park, Y.6
  • 89
    • 0031012598 scopus 로고    scopus 로고
    • Angiogenesis inhibitor TNP-470 suppresses tumorigenesis in rat urinary bladder
    • Tanaka Y, Kawamata H, Fujimoto K, Oyasu R. Angiogenesis inhibitor TNP-470 suppresses tumorigenesis in rat urinary bladder. J Urol 1997; 157: 683-8.
    • (1997) J Urol , vol.157 , pp. 683-688
    • Tanaka, Y.1    Kawamata, H.2    Fujimoto, K.3    Oyasu, R.4
  • 90
    • 0029993625 scopus 로고    scopus 로고
    • Antitumor effect of TNP-470 on glial tumors transplanted in rats
    • Isobe N, Uozumi T, Kurisu K, Kawamoto K. Antitumor effect of TNP-470 on glial tumors transplanted in rats. Anticancer Res 1996; 16: 71-6.
    • (1996) Anticancer Res , vol.16 , pp. 71-76
    • Isobe, N.1    Uozumi, T.2    Kurisu, K.3    Kawamoto, K.4
  • 91
    • 0028359292 scopus 로고
    • AGM-1470 inhibits the growth of human glioblastoma cells in vitro and in vivo
    • Takamiya Y, Brem H, Ojeifo J, Mineta T, Martuza R. AGM-1470 inhibits the growth of human glioblastoma cells in vitro and in vivo. Neurosurg 1994; 34: 869-75.
    • (1994) Neurosurg , vol.34 , pp. 869-875
    • Takamiya, Y.1    Brem, H.2    Ojeifo, J.3    Mineta, T.4    Martuza, R.5
  • 92
    • 0028111148 scopus 로고
    • Anti-proliferative effects of TNP-470 on human malignant glioma in vivo: Potent inhibition of tumor angiogenesis
    • Taki T, Ohnishi T, Arita N, Hiraga S, Saitoh Y, Izumoto S, et al. Anti-proliferative effects of TNP-470 on human malignant glioma in vivo: potent inhibition of tumor angiogenesis. J Neurooncol 1994; 19: 251-8.
    • (1994) J Neurooncol , vol.19 , pp. 251-258
    • Taki, T.1    Ohnishi, T.2    Arita, N.3    Hiraga, S.4    Saitoh, Y.5    Izumoto, S.6
  • 93
    • 0028350421 scopus 로고
    • The effect of AGM-1470 in an improved intracranial 9L gliosarcoma rat model
    • Wilson J, Penar P. The effect of AGM-1470 in an improved intracranial 9L gliosarcoma rat model. Neurol Res 1994; 16: 121-4.
    • (1994) Neurol Res , vol.16 , pp. 121-124
    • Wilson, J.1    Penar, P.2
  • 94
    • 0029875694 scopus 로고    scopus 로고
    • Uptake of temozolomide in a rat glioma model in the presence and absence of the angiogenesis inhibitor TNP-470
    • Devineni D, Klein-Szanto A, Gallo JM. Uptake of temozolomide in a rat glioma model in the presence and absence of the angiogenesis inhibitor TNP-470. Cancer Res 1996; 56: 1983-7.
    • (1996) Cancer Res , vol.56 , pp. 1983-1987
    • Devineni, D.1    Klein-Szanto, A.2    Gallo, J.M.3
  • 95
    • 0033162686 scopus 로고    scopus 로고
    • Time until initiation of tumor growth is an effective measure of the anti-angiogenic effect of TNP-470 on human glioblastoma in nude mice
    • Kragh M, Spang-Thomsen M, Kristjansen PE. Time until initiation of tumor growth is an effective measure of the anti-angiogenic effect of TNP-470 on human glioblastoma in nude mice. Oncol Rep 1999; 6: 759-62.
    • (1999) Oncol Rep , vol.6 , pp. 759-762
    • Kragh, M.1    Spang-Thomsen, M.2    Kristjansen, P.E.3
  • 96
    • 0031909427 scopus 로고    scopus 로고
    • The effect of the anti-angiogenic agent TNP-470 on tumor growth and vascularity in low passaged xenografts of human gliomas in nude mice
    • Bernsen H, Rijken P, Peters H, Bakker H, Van der Kogel A. The effect of the anti-angiogenic agent TNP-470 on tumor growth and vascularity in low passaged xenografts of human gliomas in nude mice. J Neurooncol 1998; 38: 51-7.
    • (1998) J Neurooncol , vol.38 , pp. 51-57
    • Bernsen, H.1    Rijken, P.2    Peters, H.3    Bakker, H.4    Van Der Kogel, A.5
  • 97
    • 0028670833 scopus 로고
    • Integrin alpha vbeta3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
    • Brooks P, Montgomery A, Rosenfeld M, Reisfeld R, Hu T, Klier G, et al. Integrin alpha vbeta3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 1994; 79: 1157-64.
    • (1994) Cell , vol.79 , pp. 1157-1164
    • Brooks, P.1    Montgomery, A.2    Rosenfeld, M.3    Reisfeld, R.4    Hu, T.5    Klier, G.6
  • 98
    • 0033870756 scopus 로고    scopus 로고
    • Targered antiangiogenic therapy for cancer using Vitaxin: A humanized monoclonal antibody to the integrin alphavbeta3
    • Gutheil JC, Campbell TN, Pierce PR, Watkins JD, Huse WD, Bodkin DJ, et al. Targered antiangiogenic therapy for cancer using Vitaxin: a humanized monoclonal antibody to the integrin alphavbeta3. Clin Cancer Res 2000; 6: 3056-61.
    • (2000) Clin Cancer Res , vol.6 , pp. 3056-3061
    • Gutheil, J.C.1    Campbell, T.N.2    Pierce, P.R.3    Watkins, J.D.4    Huse, W.D.5    Bodkin, D.J.6
  • 99
    • 0035149747 scopus 로고    scopus 로고
    • Preferential susceptibility of brain tumors to the antiangiogenic effects of an alpha(v) integrin antagonist
    • MacDonald TJ, Taga T, Shimada H, Tabrizi P, Zlokovic BV, Cheresh DA, et al. Preferential susceptibility of brain tumors to the antiangiogenic effects of an alpha(v) integrin antagonist. Neurosurg 2001; 48: 151-7.
    • (2001) Neurosurg , vol.48 , pp. 151-157
    • MacDonald, T.J.1    Taga, T.2    Shimada, H.3    Tabrizi, P.4    Zlokovic, B.V.5    Cheresh, D.A.6
  • 100
    • 0037051697 scopus 로고    scopus 로고
    • Alpha v-integrin antagonist EMD 121974 induces apoprosis in brain tumor cells growing on vitronecrin and tenascin
    • Taga T, Suzuki A, Gonzalez-Gomez I, Gilles FH, Stins M, Shimada H, et al. Alpha v-integrin antagonist EMD 121974 induces apoprosis in brain tumor cells growing on vitronecrin and tenascin. Int J Cancer 2002; 98: 690-7.
    • (2002) Int J Cancer , vol.98 , pp. 690-697
    • Taga, T.1    Suzuki, A.2    Gonzalez-Gomez, I.3    Gilles, F.H.4    Stins, M.5    Shimada, H.6
  • 101
    • 0035893737 scopus 로고    scopus 로고
    • Simultaneous inhibition of glioma angiogenesis, cell proliferation, and invasion by a naturally occurring fragment of human metalloproteinase-2
    • Bello L, Lucini V, Carrabba G, Giussani C, Machluf M, Pluderi TA, et al. Simultaneous inhibition of glioma angiogenesis, cell proliferation, and invasion by a naturally occurring fragment of human metalloproteinase-2. Cancer Res 2001; 61: 8730-6.
    • (2001) Cancer Res , vol.61 , pp. 8730-8736
    • Bello, L.1    Lucini, V.2    Carrabba, G.3    Giussani, C.4    Machluf, M.5    Pluderi, T.A.6
  • 102
    • 0033205228 scopus 로고    scopus 로고
    • Inhibition of neovascularization and tumor growth, and facilitation of wound repair, by halofuginone, an inhibitor of collagen type I synthesis
    • Abramovitch R, Dafni H, Neeman M, Nagler A, Pines M. Inhibition of neovascularization and tumor growth, and facilitation of wound repair, by halofuginone, an inhibitor of collagen type I synthesis. Neoplasia 1999; 1: 321-9.
    • (1999) Neoplasia , vol.1 , pp. 321-329
    • Abramovitch, R.1    Dafni, H.2    Neeman, M.3    Nagler, A.4    Pines, M.5
  • 103
    • 0032837028 scopus 로고    scopus 로고
    • Broad antitumor and antiangiogenic activities of AG3340, a potent and selective MMP inhibitor undergoing advanced oncology clinical trials
    • Shalinsky DR, Brekken J, Zou H, McDermott CD, Forsyth P, Edwards D, et al. Broad antitumor and antiangiogenic activities of AG3340, a potent and selective MMP inhibitor undergoing advanced oncology clinical trials. Ann N Y Acad Sci 1999; 878: 236-70.
    • (1999) Ann N Y Acad Sci , vol.878 , pp. 236-270
    • Shalinsky, D.R.1    Brekken, J.2    Zou, H.3    McDermott, C.D.4    Forsyth, P.5    Edwards, D.6
  • 104
    • 85047699234 scopus 로고    scopus 로고
    • Intratumoral gene therapy of malignant brain rumor in a rat model with angiostatin delivered by adeno-associated viral (AAV) vector
    • Ma HI, Lin SZ, Chiang YH, Li J, Chen SL, Tsao YP, et al. Intratumoral gene therapy of malignant brain rumor in a rat model with angiostatin delivered by adeno-associated viral (AAV) vector. Gene Ther 2002; 9: 2-11.
    • (2002) Gene Ther , vol.9 , pp. 2-11
    • Ma, H.I.1    Lin, S.Z.2    Chiang, Y.H.3    Li, J.4    Chen, S.L.5    Tsao, Y.P.6
  • 105
    • 0035887463 scopus 로고    scopus 로고
    • Low-dose chemotherapy combined with an antiangiogenic drug reduces human glioma growth in vivo
    • Bello L, Carrabba G, Giussani C, Lucini V, Cerutti F, Scaglione F, et al. Low-dose chemotherapy combined with an antiangiogenic drug reduces human glioma growth in vivo. Cancer Res 2001; 61: 7501-6.
    • (2001) Cancer Res , vol.61 , pp. 7501-7506
    • Bello, L.1    Carrabba, G.2    Giussani, C.3    Lucini, V.4    Cerutti, F.5    Scaglione, F.6
  • 106
    • 0032403589 scopus 로고    scopus 로고
    • Protamine inhibits angiogenesis and growth of C6 rat glioma; a synergistic effect when combined with carmustine
    • Arrieta O, Guevara P, Reyes S, Ortiz A, Rembao D, Sotelo J. Protamine inhibits angiogenesis and growth of C6 rat glioma; a synergistic effect when combined with carmustine. Eur J Cancer 1998; 34: 2101-6.
    • (1998) Eur J Cancer , vol.34 , pp. 2101-2106
    • Arrieta, O.1    Guevara, P.2    Reyes, S.3    Ortiz, A.4    Rembao, D.5    Sotelo, J.6
  • 107
    • 0034682473 scopus 로고    scopus 로고
    • A peptide derived from the non-receptor-binding region of urokinase plasminogen activator inhibits glioblastoma growth and angiogenesis in vivo in combination with cisplatin
    • Mishima K, Mazar A, Gown A, Skelly M, Ji X, Wang X, et al. A peptide derived from the non-receptor-binding region of urokinase plasminogen activator inhibits glioblastoma growth and angiogenesis in vivo in combination with cisplatin. Proc Natl Acad Sci USA 2000; 97: 8484-9.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 8484-8489
    • Mishima, K.1    Mazar, A.2    Gown, A.3    Skelly, M.4    Ji, X.5    Wang, X.6
  • 108
    • 0028305809 scopus 로고
    • Potentiation of cytotoxic cancer therapies by TNP-470 alone and with other anti-angiogenic agents
    • Teicher B, Holden S, Ara G, Sotomayor E, Huang Z, Chen Y, et al. Potentiation of cytotoxic cancer therapies by TNP-470 alone and with other anti-angiogenic agents. Int J Cancer 1994; 57: 920-5.
    • (1994) Int J Cancer , vol.57 , pp. 920-925
    • Teicher, B.1    Holden, S.2    Ara, G.3    Sotomayor, E.4    Huang, Z.5    Chen, Y.6
  • 109
    • 0028943249 scopus 로고
    • The role of minocycline in the treatment of intracranial 9L glioma
    • Weingart JD, Sipos EP, Brem H. The role of minocycline in the treatment of intracranial 9L glioma. J Neurosurg 1995; 82: 635-40.
    • (1995) J Neurosurg , vol.82 , pp. 635-640
    • Weingart, J.D.1    Sipos, E.P.2    Brem, H.3
  • 110
    • 0031951530 scopus 로고    scopus 로고
    • Adenoviral TNF-alpha gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft
    • Staba MJ, Mauceri HJ, Kufe DW, Hallahan DE, Weichselbaum RR. Adenoviral TNF-alpha gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft. Gene Ther 1998; 5: 293-300.
    • (1998) Gene Ther , vol.5 , pp. 293-300
    • Staba, M.J.1    Mauceri, H.J.2    Kufe, D.W.3    Hallahan, D.E.4    Weichselbaum, R.R.5
  • 111
    • 17444376781 scopus 로고    scopus 로고
    • Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin
    • Gorski D, Mauceri H, Salloum R, Gately S, Hellman S, Beckett M, et al. Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin. Cancer Res 1998; 58: 5686-9.
    • (1998) Cancer Res , vol.58 , pp. 5686-5689
    • Gorski, D.1    Mauceri, H.2    Salloum, R.3    Gately, S.4    Hellman, S.5    Beckett, M.6
  • 112
    • 0035132923 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor-2-blocking antibody potentiates radiation-induced long-term control of human tumor xenografts
    • Kozin SV, Boucher Y, Hicklin DJ, Bohlen P, Jain RK, Suit HD. Vascular endothelial growth factor receptor-2-blocking antibody potentiates radiation-induced long-term control of human tumor xenografts. Cancer Res 2001; 61: 39-44.
    • (2001) Cancer Res , vol.61 , pp. 39-44
    • Kozin, S.V.1    Boucher, Y.2    Hicklin, D.J.3    Bohlen, P.4    Jain, R.K.5    Suit, H.D.6
  • 114
    • 0034099423 scopus 로고    scopus 로고
    • Therapeutic synergy of TNP-470 and ionizing radiation: Effects on tumor growth, vessel morphology, and angiogenesis in human glioblastoma multiforme xenografts
    • Lund E, Bastholm L, Kristjansen P. Therapeutic synergy of TNP-470 and ionizing radiation: effects on tumor growth, vessel morphology, and angiogenesis in human glioblastoma multiforme xenografts. Clin Cancer Res 2000; 6: 971-8.
    • (2000) Clin Cancer Res , vol.6 , pp. 971-978
    • Lund, E.1    Bastholm, L.2    Kristjansen, P.3
  • 115
    • 0035866771 scopus 로고    scopus 로고
    • Inhibition of vascular endothelial growth factor receptor signaling leads to reversal of tumor resistance to radiotherapy
    • Geng L, Donnelly E, McMahon G, Lin PC, Sierra-Rivera E, Oshinka H, et al. Inhibition of vascular endothelial growth factor receptor signaling leads to reversal of tumor resistance to radiotherapy. Cancer Res 2001; 61: 2413-9.
    • (2001) Cancer Res , vol.61 , pp. 2413-2419
    • Geng, L.1    Donnelly, E.2    McMahon, G.3    Lin, P.C.4    Sierra-Rivera, E.5    Oshinka, H.6
  • 116
    • 0033954292 scopus 로고    scopus 로고
    • Phase II trial of the antiangiogenic agent thalidomide in patients with recurrent high-grade gliomas
    • Fine H, Figg W, Jaeckle K, Wen P, Kyritsis A, Loeffler J, et al. Phase II trial of the antiangiogenic agent thalidomide in patients with recurrent high-grade gliomas. J Clin Oncol 2000; 18: 708-15.
    • (2000) J Clin Oncol , vol.18 , pp. 708-715
    • Fine, H.1    Figg, W.2    Jaeckle, K.3    Wen, P.4    Kyritsis, A.5    Loeffler, J.6
  • 117
    • 0033652601 scopus 로고    scopus 로고
    • Marimastat: The clinical development of a matrix metalloproteinase inhibitor
    • Steward WP, Thomas AL. Marimastat: the clinical development of a matrix metalloproteinase inhibitor. Expert Opin Investig Drugs 2000; 9: 2913-22.
    • (2000) Expert Opin Investig Drugs , vol.9 , pp. 2913-2922
    • Steward, W.P.1    Thomas, A.L.2
  • 118
    • 0037208589 scopus 로고    scopus 로고
    • Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer
    • Kabbinavar F, Hurwitz HI, Fehrenbacher L, Meropol NJ, Novotny WF, Lieberman G, et al. Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer. J Clin Oncol 2003; 21: 60-5.
    • (2003) J Clin Oncol , vol.21 , pp. 60-65
    • Kabbinavar, F.1    Hurwitz, H.I.2    Fehrenbacher, L.3    Meropol, N.J.4    Novotny, W.F.5    Lieberman, G.6
  • 119
    • 11144354392 scopus 로고    scopus 로고
    • Direct evidence that the VEGF-specific antibody bevacizucnab has antivascular effects in human rectal cancer
    • Epub 2004 Jan 25
    • Willett CG, Boucher Y, Di Tomaso E, Duda DG, Munn LL, Tong RT, et al. Direct evidence that the VEGF-specific antibody bevacizucnab has antivascular effects in human rectal cancer. Nat Med 2004; 10: 145-7; Epub 2004 Jan 25.
    • (2004) Nat Med , vol.10 , pp. 145-147
    • Willett, C.G.1    Boucher, Y.2    Di Tomaso, E.3    Duda, D.G.4    Munn, L.L.5    Tong, R.T.6
  • 120
    • 0043177668 scopus 로고    scopus 로고
    • Bevacizumab (a monoclonal antibody to vascular endothelial growth factor) prolongs survival in first-line colorectal cancer (CRC): Results of a phase III trial of bevacizumab in combination with bolus IFL (irinotecan, 5-fluorouacil, leucovorin) as first line theray in subjects with metastatic CRC
    • Abst. 3646
    • Hurwitz HI, Fehrenbacher L, Cartwright T, Hainsworth J, Heim W, Berlin J, et al. Bevacizumab (a monoclonal antibody to vascular endothelial growth factor) prolongs survival in first-line colorectal cancer (CRC): results of a phase III trial of bevacizumab in combination with bolus IFL (irinotecan, 5-fluorouacil, leucovorin) as first line theray in subjects with metastatic CRC. Proc Am Soc Clin Oncol 2003: 22; [Abst. 3646].
    • (2003) Proc Am Soc Clin Oncol , vol.22
    • Hurwitz, H.I.1    Fehrenbacher, L.2    Cartwright, T.3    Hainsworth, J.4    Heim, W.5    Berlin, J.6
  • 121
    • 0027197245 scopus 로고
    • Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
    • Kim KJ, Li B, Winer J, Armanini M, Gillett N, Phillips HS, et al. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 1993; 362: 841-4.
    • (1993) Nature , vol.362 , pp. 841-844
    • Kim, K.J.1    Li, B.2    Winer, J.3    Armanini, M.4    Gillett, N.5    Phillips, H.S.6
  • 122
    • 0029949160 scopus 로고    scopus 로고
    • Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody
    • Yuan F, Chen Y, Dellian M, Safabakhsh N, Ferrara N, Jain RK. Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody. Proc Natl Acad Sci USA 1996; 93: 14765-70.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 14765-14770
    • Yuan, F.1    Chen, Y.2    Dellian, M.3    Safabakhsh, N.4    Ferrara, N.5    Jain, R.K.6
  • 123
    • 0031660845 scopus 로고    scopus 로고
    • Delayed vascular changes after antiangiogenic therapy with antivascular endothelial growth factor antibodies in human glioma xenografts in nude mice
    • Bernsen H, Rijken P, Peters J, Bakker H, Van der Kogel A. Delayed vascular changes after antiangiogenic therapy with antivascular endothelial growth factor antibodies in human glioma xenografts in nude mice. Neurosurg 1998; 43: 570-5.
    • (1998) Neurosurg , vol.43 , pp. 570-575
    • Bernsen, H.1    Rijken, P.2    Peters, J.3    Bakker, H.4    Van Der Kogel, A.5
  • 124
    • 0032698140 scopus 로고    scopus 로고
    • Antivascular endothelial growth factor receptor (fetal liver kinase 1) monoclonal antibody inhibits tumor angiogenesis and growth of several mouse and human tumors
    • Prewett M, Huber J, Li Y, Santiago A, O'Connor W, King K, et al. Antivascular endothelial growth factor receptor (fetal liver kinase 1) monoclonal antibody inhibits tumor angiogenesis and growth of several mouse and human tumors. Cancer Res 1999; 59: 5209-18.
    • (1999) Cancer Res , vol.59 , pp. 5209-5218
    • Prewett, M.1    Huber, J.2    Li, Y.3    Santiago, A.4    O'Connor, W.5    King, K.6
  • 125
    • 0028174337 scopus 로고
    • Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant
    • Millauer B, Shawver L, Plate K, Risau W, Ullrich A. Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant. Nature 1994; 367: 576-9.
    • (1994) Nature , vol.367 , pp. 576-579
    • Millauer, B.1    Shawver, L.2    Plate, K.3    Risau, W.4    Ullrich, A.5
  • 126
    • 0033134716 scopus 로고    scopus 로고
    • Antiangiogenic gene therapy in a rat glioma model using a dominant-negative vascular endothelial growth factor receptor 2
    • Machein M, Risau W, Plate K. Antiangiogenic gene therapy in a rat glioma model using a dominant-negative vascular endothelial growth factor receptor 2. Hum Gene Ther 1999; 10: 1117-28.
    • (1999) Hum Gene Ther , vol.10 , pp. 1117-1128
    • Machein, M.1    Risau, W.2    Plate, K.3
  • 127
    • 13144262858 scopus 로고    scopus 로고
    • Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate
    • Goldman C, Kendall R, Cabrera G, Soroceanu L, Heike Y, Gillespie G, et al. Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate. Proc Natl Acad Sci USA 1998; 95: 8795-800.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8795-8800
    • Goldman, C.1    Kendall, R.2    Cabrera, G.3    Soroceanu, L.4    Heike, Y.5    Gillespie, G.6
  • 128
    • 0028044984 scopus 로고
    • The efficacy and distribution of suramin in the treatment of the 9L gliosarcoma
    • discussion: pages
    • Olson JJ, Polk DM, Reisner A. The efficacy and distribution of suramin in the treatment of the 9L gliosarcoma. Neurosurg 1994; 34: 297-308; [discussion: pages].
    • (1994) Neurosurg , vol.34 , pp. 297-308
    • Olson, J.J.1    Polk, D.M.2    Reisner, A.3
  • 129
    • 0028318791 scopus 로고
    • Suramin, an anticancer and angiosuppressive agent, inhibits endothelial cell binding of basic fibroblast growth factor, migration, proliferation, and induction of urokinase-type plasminogen activator
    • Takano S, Gately S, Neville ME, Herblin WF, Gross JL, Engelhard H, et al. Suramin, an anticancer and angiosuppressive agent, inhibits endothelial cell binding of basic fibroblast growth factor, migration, proliferation, and induction of urokinase-type plasminogen activator. Cancer Res 1994; 54: 2654-60.
    • (1994) Cancer Res , vol.54 , pp. 2654-2660
    • Takano, S.1    Gately, S.2    Neville, M.E.3    Herblin, W.F.4    Gross, J.L.5    Engelhard, H.6
  • 130
    • 0035839236 scopus 로고    scopus 로고
    • Abolished angiogenicity and tumorigenicity of rat glioma by 1-naphthalenemonosulfonate
    • Cuevas P, Carceller F, Diaz D, Reimers D, Fernandez M, Lozano RM, et al. Abolished angiogenicity and tumorigenicity of rat glioma by 1- naphthalenemonosulfonate. Neurosci Lett 2001; 308: 185-8.
    • (2001) Neurosci Lett , vol.308 , pp. 185-188
    • Cuevas, P.1    Carceller, F.2    Diaz, D.3    Reimers, D.4    Fernandez, M.5    Lozano, R.M.6
  • 131
    • 0029040021 scopus 로고
    • In vivo inhibition of angiogenesis and growth of the human U-87 malignant glial tumor by treatment with an antibody against basic fibroblast growth factor
    • Stan AC, Nemati MN, Piersch T, Walter GF, Dietz H. In vivo inhibition of angiogenesis and growth of the human U-87 malignant glial tumor by treatment with an antibody against basic fibroblast growth factor. J Neurosurg 1995; 82: 1044-52.
    • (1995) J Neurosurg , vol.82 , pp. 1044-1052
    • Stan, A.C.1    Nemati, M.N.2    Piersch, T.3    Walter, G.F.4    Dietz, H.5
  • 132
    • 0033493488 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer of a truncated form of fibroblast growth factor receptor inhibits growth of glioma cells both in vitro and in vivo
    • Saiki M, Mima T, Takahashi JC, Tani S, Yukawa H, Ueno H, et al. Adenovirus-mediated gene transfer of a truncated form of fibroblast growth factor receptor inhibits growth of glioma cells both in vitro and in vivo. J Neurooncol 1999; 44: 195-203.
    • (1999) J Neurooncol , vol.44 , pp. 195-203
    • Saiki, M.1    Mima, T.2    Takahashi, J.C.3    Tani, S.4    Yukawa, H.5    Ueno, H.6
  • 133
    • 0035866394 scopus 로고    scopus 로고
    • Inhibition of fibroblast growth factor/fibroblast growth factor receptor activity in glioma cells impedes tumor growth by both angiogenesis-dependent and -independent mechanisms
    • Auguste P, Gursel DB, Lemiere S, Reimers D, Cuevas P, Carceller F, et al. Inhibition of fibroblast growth factor/fibroblast growth factor receptor activity in glioma cells impedes tumor growth by both angiogenesis-dependent and -independent mechanisms. Cancer Res 2001; 61: 1717-26.
    • (2001) Cancer Res , vol.61 , pp. 1717-1726
    • Auguste, P.1    Gursel, D.B.2    Lemiere, S.3    Reimers, D.4    Cuevas, P.5    Carceller, F.6
  • 134
    • 0030937456 scopus 로고    scopus 로고
    • Viral vector-mediated transduction of a modified platelet factor 4 cDNA inhibits angiogenesis and tumor growth
    • Tanaka T, Manome Y, Wen P, Kufe D, Fine H. Viral vector-mediated transduction of a modified platelet factor 4 cDNA inhibits angiogenesis and tumor growth. Nat Med 1997; 3: 437-42.
    • (1997) Nat Med , vol.3 , pp. 437-442
    • Tanaka, T.1    Manome, Y.2    Wen, P.3    Kufe, D.4    Fine, H.5
  • 135
    • 0036365052 scopus 로고    scopus 로고
    • In vivo targeting of SF/HGF and c-met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis
    • Abounader R, Lal B, Luddy C, Koe G, Davidson B, Rosen EM, et al. In vivo targeting of SF/HGF and c-met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis. FASEB J 2002; 16: 108-10.
    • (2002) FASEB J , vol.16 , pp. 108-110
    • Abounader, R.1    Lal, B.2    Luddy, C.3    Koe, G.4    Davidson, B.5    Rosen, E.M.6
  • 136
    • 0141925943 scopus 로고    scopus 로고
    • Inhibition of intracerebral glioblastoma growth by local treatment with the scatter factor/hepatocyte growth factor-antagonist NK4
    • Brockmann MA, Papadimitriou A, Brandt M, Filibrandt R, Westphal M, Lamszus K. Inhibition of intracerebral glioblastoma growth by local treatment with the scatter factor/hepatocyte growth factor-antagonist NK4. Clin Cancer Res 2003; 9: 4578-85.
    • (2003) Clin Cancer Res , vol.9 , pp. 4578-4585
    • Brockmann, M.A.1    Papadimitriou, A.2    Brandt, M.3    Filibrandt, R.4    Westphal, M.5    Lamszus, K.6
  • 137
    • 15644374381 scopus 로고    scopus 로고
    • Squalamine inhibits angiogenesis and solid tumor growth in vivo and perturbs embryonic vasculature
    • Sills Jr AK, Williams JI, Tyler BM, Epstein DS, Sipos EP, Davis JD, et al. Squalamine inhibits angiogenesis and solid tumor growth in vivo and perturbs embryonic vasculature. Cancer Res 1998; 58: 2784-92.
    • (1998) Cancer Res , vol.58 , pp. 2784-2792
    • Sills Jr., A.K.1    Williams, J.I.2    Tyler, B.M.3    Epstein, D.S.4    Sipos, E.P.5    Davis, J.D.6
  • 138
    • 0023904597 scopus 로고
    • Effect of ibuprofen on tumor growth in the C6 spheroid implantation glioma model
    • Farrell CL, Megyesi J, Del Maestro RF. Effect of ibuprofen on tumor growth in the C6 spheroid implantation glioma model. J Neurosurg 1988; 68: 925-30.
    • (1988) J Neurosurg , vol.68 , pp. 925-930
    • Farrell, C.L.1    Megyesi, J.2    Del Maestro, R.F.3
  • 139
    • 0033178714 scopus 로고    scopus 로고
    • Restoration of wild-type p16 down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human gliomas
    • Harada H, Nakagawa K, Iwata S, Saito M, Kumon Y, Sakaki S, et al. Restoration of wild-type p16 down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human gliomas. Cancer Res 1999; 59: 3783-9.
    • (1999) Cancer Res , vol.59 , pp. 3783-3789
    • Harada, H.1    Nakagawa, K.2    Iwata, S.3    Saito, M.4    Kumon, Y.5    Sakaki, S.6
  • 140
    • 0032568632 scopus 로고    scopus 로고
    • Angiostatin gene transfer: Inhibition of tumor growth in vivo by blockage of endothelial cell proliferation associated with a mitosis arrest
    • Griscelli F, Li H, Bennaceur-Griscelli A, Soria J, Opolon P, Soria C, et al. Angiostatin gene transfer: inhibition of tumor growth in vivo by blockage of endothelial cell proliferation associated with a mitosis arrest. Proc Natl Acad Sci USA 1998; 95: 6367-72.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6367-6372
    • Griscelli, F.1    Li, H.2    Bennaceur-Griscelli, A.3    Soria, J.4    Opolon, P.5    Soria, C.6
  • 141
    • 0036468564 scopus 로고    scopus 로고
    • Suppression of intracranial human glioma growth after intramuscular administration of an adeno-associated viral vector expressing angiostatin
    • Ma HI, Guo P, Li J, Lin SZ, Chiang YH, Xiao X, et al. Suppression of intracranial human glioma growth after intramuscular administration of an adeno-associated viral vector expressing angiostatin. Cancer Res 2002; 62: 756-63.
    • (2002) Cancer Res , vol.62 , pp. 756-763
    • Ma, H.I.1    Guo, P.2    Li, J.3    Lin, S.Z.4    Chiang, Y.H.5    Xiao, X.6
  • 142
    • 0032145376 scopus 로고    scopus 로고
    • Viral vector-targeted antiangiogenic gene therapy utilizing an angiostatin complementary DNA
    • Tanaka T, Cao Y, Folkman J, Fine HA. Viral vector-targeted antiangiogenic gene therapy utilizing an angiostatin complementary DNA. Cancer Res 1998; 58: 3362-9.
    • (1998) Cancer Res , vol.58 , pp. 3362-3369
    • Tanaka, T.1    Cao, Y.2    Folkman, J.3    Fine, H.A.4
  • 143
    • 0037138433 scopus 로고    scopus 로고
    • Antiangiogenic activiry of endostatin inhibits C6 glioma growth
    • Peroulis I, Jonas N, Saleh M. Antiangiogenic activiry of endostatin inhibits C6 glioma growth. Int J Cancer 2002; 97: 839-45.
    • (2002) Int J Cancer , vol.97 , pp. 839-845
    • Peroulis, I.1    Jonas, N.2    Saleh, M.3
  • 144
    • 9144265679 scopus 로고    scopus 로고
    • Combined therapy with direct and indirect angiogenesis inhibition results in enhanced antiangiogenic and antitumor effects
    • Abdollahi A, Lipson KE, Sckell A, Zieher H, Klenke F, Poerschke D, et al. Combined therapy with direct and indirect angiogenesis inhibition results in enhanced antiangiogenic and antitumor effects. Cancer Res 2003; 63: 8890-8.
    • (2003) Cancer Res , vol.63 , pp. 8890-8898
    • Abdollahi, A.1    Lipson, K.E.2    Sckell, A.3    Zieher, H.4    Klenke, F.5    Poerschke, D.6
  • 145
    • 18344363184 scopus 로고    scopus 로고
    • Endostatin reduces vascularization, blood flow, and growth in a rat gliosarcoma
    • Sorensen DR, Read TA, Porwol T, Olsen BR, Timpl R, Sasaki T, et al. Endostatin reduces vascularization, blood flow, and growth in a rat gliosarcoma. Neurooncol 2002; 4: 1-8.
    • (2002) Neurooncol , vol.4 , pp. 1-8
    • Sorensen, D.R.1    Read, T.A.2    Porwol, T.3    Olsen, B.R.4    Timpl, R.5    Sasaki, T.6
  • 146
    • 0033518887 scopus 로고    scopus 로고
    • Effect of in situ retroviral interleukin-4 transfer on established intracranial tumors
    • Saleh M, Wiegmans A, Malone Q, Stylli SS, Kaye AH. Effect of in situ retroviral interleukin-4 transfer on established intracranial tumors. J Natl Cancer Inst 1999; 91: 438-45.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 438-445
    • Saleh, M.1    Wiegmans, A.2    Malone, Q.3    Stylli, S.S.4    Kaye, A.H.5
  • 147
    • 0036570056 scopus 로고    scopus 로고
    • Antivasculature effects of doxorubicin-containing liposomes in an intracranial rat brain tumor model
    • Zhou R, Mazurchuk R, Srraubinger RM. Antivasculature effects of doxorubicin-containing liposomes in an intracranial rat brain tumor model. Cancer Res 2002; 62: 2561-6.
    • (2002) Cancer Res , vol.62 , pp. 2561-2566
    • Zhou, R.1    Mazurchuk, R.2    Srraubinger, R.M.3
  • 148
    • 0036117240 scopus 로고    scopus 로고
    • Neutralization of adrenomedullin inhibits the growth of human glioblastoma cell lines in vitro and suppresses tumor xenograft growth in vivo
    • Ouafik L, Sauze S, Boudouresque F, Chinot O, Delfino C, Fina F, et al. Neutralization of adrenomedullin inhibits the growth of human glioblastoma cell lines in vitro and suppresses tumor xenograft growth in vivo. Am J Pathol 2002; 160: 1279-92.
    • (2002) Am J Pathol , vol.160 , pp. 1279-1292
    • Ouafik, L.1    Sauze, S.2    Boudouresque, F.3    Chinot, O.4    Delfino, C.5    Fina, F.6
  • 149
    • 0141841681 scopus 로고    scopus 로고
    • Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis
    • Gondi CS, Lakka SS, Yanamandra N, Siddique K, Dinh DH, Olivero WC, et al. Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis. Oncogene 2003; 22: 5967-75.
    • (2003) Oncogene , vol.22 , pp. 5967-5975
    • Gondi, C.S.1    Lakka, S.S.2    Yanamandra, N.3    Siddique, K.4    Dinh, D.H.5    Olivero, W.C.6
  • 150
    • 0038181212 scopus 로고    scopus 로고
    • Synergistic down-regulation of urokinase plasminogen activator receptor and matrix metalloproteinase-9 in SNB19 glioblastoma cells efficiently inhibits glioma cell invasion, angiogenesis, and tumor growth
    • Lakka SS, Gondi CS, Yanamandta N, Dinh DH, Olivero WC, Gujrati M, et al. Synergistic down-regulation of urokinase plasminogen activator receptor and matrix metalloproteinase-9 in SNB19 glioblastoma cells efficiently inhibits glioma cell invasion, angiogenesis, and tumor growth. Cancer Res 2003; 63: 2454-61.
    • (2003) Cancer Res , vol.63 , pp. 2454-2461
    • Lakka, S.S.1    Gondi, C.S.2    Yanamandta, N.3    Dinh, D.H.4    Olivero, W.C.5    Gujrati, M.6
  • 151
    • 0034899448 scopus 로고    scopus 로고
    • Antiangiogenic and antitumor effects of a protein kinase Cbeta inhibitor in human T98G glioblastoma multiforme xenografts
    • Teicher BA, Menon K, Alvarez E, Galbreath E, Shih C, Faul M. Antiangiogenic and antitumor effects of a protein kinase Cbeta inhibitor in human T98G glioblastoma multiforme xenografts. Clin Cancer Res 2001; 7: 634-40.
    • (2001) Clin Cancer Res , vol.7 , pp. 634-640
    • Teicher, B.A.1    Menon, K.2    Alvarez, E.3    Galbreath, E.4    Shih, C.5    Faul, M.6
  • 152
    • 18244419396 scopus 로고    scopus 로고
    • Combined effects of angiostatin and ionizing radiation in antitumour therapy
    • Mauceri H, Hanna N, Beckett M, Gorski D, Staba M, Stellato K, et al. Combined effects of angiostatin and ionizing radiation in antitumour therapy. Nature 1998; 394: 287-91.
    • (1998) Nature , vol.394 , pp. 287-291
    • Mauceri, H.1    Hanna, N.2    Beckett, M.3    Gorski, D.4    Staba, M.5    Stellato, K.6
  • 153
    • 0041672482 scopus 로고    scopus 로고
    • SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models
    • Schueneman AJ, Himmeifarb E, Geng L, Tan J, Donnelly E, Mendel D, et al. SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models. Cancer Res 2003; 63: 4009-16.
    • (2003) Cancer Res , vol.63 , pp. 4009-4016
    • Schueneman, A.J.1    Himmeifarb, E.2    Geng, L.3    Tan, J.4    Donnelly, E.5    Mendel, D.6


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