-
1
-
-
0031789314
-
Predictive value of vascular endothelial growth factor (VEGF) in metastasis and prognosis of human colorectal cancer
-
Ishigami, S-I., Arii, S., Furutani, M., Niwano, M., Harada, T., Mizumoto, M., Mori, A., Onodera, H., and Imamura, M. Predictive value of vascular endothelial growth factor (VEGF) in metastasis and prognosis of human colorectal cancer. Br. J. Cancer, 78: 1379-1384, 1998.
-
(1998)
Br. J. Cancer
, vol.78
, pp. 1379-1384
-
-
Ishigami, S.-I.1
Arii, S.2
Furutani, M.3
Niwano, M.4
Harada, T.5
Mizumoto, M.6
Mori, A.7
Onodera, H.8
Imamura, M.9
-
2
-
-
0030829035
-
Enhanced expression of vascular endothehal growth factor in metastatic melanoma
-
Salven, P., Heikkila, P., and Joensuu, H. Enhanced expression of vascular endothehal growth factor in metastatic melanoma. Br. J. Cancer, 76: 930-934, 1997.
-
(1997)
Br. J. Cancer
, vol.76
, pp. 930-934
-
-
Salven, P.1
Heikkila, P.2
Joensuu, H.3
-
3
-
-
0031779403
-
Tumour angiogenesis and vascular endothelial growth factor expression in stage I lung adenocarcinoma
-
Shibusa, T., Shijubo, N. And Abe, S. Tumour angiogenesis and vascular endothelial growth factor expression in stage I lung adenocarcinoma. Clin. Cancer Res., 4: 1483-1487, 1998.
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 1483-1487
-
-
Shibusa, T.1
Shijubo, N.A.2
Abe, S.3
-
4
-
-
0031955262
-
Expression of vascular endothelial growth factor correlates with tumour progression in gallbladder cancer clinical studies
-
Okita, S., Kondoh, S., Shiraishi, K., Kaino, S., Hatano, S., and Okita, K. Expression of vascular endothelial growth factor correlates with tumour progression in gallbladder cancer clinical studies. Int. J. Oncol., 12: 1013-1018, 1998.
-
(1998)
Int. J. Oncol.
, vol.12
, pp. 1013-1018
-
-
Okita, S.1
Kondoh, S.2
Shiraishi, K.3
Kaino, S.4
Hatano, S.5
Okita, K.6
-
5
-
-
0031941942
-
Vascular endothelial growth factor expression and vascular density as prognostic markers of survival in patients with low-grade astrocytoma
-
Abdulrauf, S. I., Edvardsen, K., Ho, K. L., Yang, X. Y., Rock, J. P., and Rosenblum, M. L. Vascular endothelial growth factor expression and vascular density as prognostic markers of survival in patients with low-grade astrocytoma. J. Neurosurg., 88: 513-520, 1998.
-
(1998)
J. Neurosurg.
, vol.88
, pp. 513-520
-
-
Abdulrauf, S.I.1
Edvardsen, K.2
Ho, K.L.3
Yang, X.Y.4
Rock, J.P.5
Rosenblum, M.L.6
-
6
-
-
0344109584
-
Markers of tumour angiogenesis and proteolysis independently define high- and low-risk subsets of node-negative breast cancer patients
-
Eppenberger, U., Kueng, W., Schlaeppi, J-M., Roesel, J. L., Benz, C., Mueller, H., Matter, A., Zuber, M., Luescher, K., Litschgi, M., Schmitt, M., Foekens, J. A., and Eppenberger-Castori, S. Markers of tumour angiogenesis and proteolysis independently define high- and low-risk subsets of node-negative breast cancer patients. J. Clin. Oncol., 16: 3129-3136, 1998.
-
(1998)
J. Clin. Oncol.
, vol.16
, pp. 3129-3136
-
-
Eppenberger, U.1
Kueng, W.2
Schlaeppi, J.-M.3
Roesel, J.L.4
Benz, C.5
Mueller, H.6
Matter, A.7
Zuber, M.8
Luescher, K.9
Litschgi, M.10
Schmitt, M.11
Foekens, J.A.12
Eppenberger-Castori, S.13
-
7
-
-
0024801035
-
Vascular permeability factor, an endothelial cell mitogen related to PDGF
-
Washington DC
-
Keck, P. J., Hauser, S. D., Krivi, G., Sanzo, K., Warren, T., Feder, J., and Connolly, D. T. Vascular permeability factor, an endothelial cell mitogen related to PDGF. Science (Washington DC), 246: 1309-1312, 1989.
-
(1989)
Science
, vol.246
, pp. 1309-1312
-
-
Keck, P.J.1
Hauser, S.D.2
Krivi, G.3
Sanzo, K.4
Warren, T.5
Feder, J.6
Connolly, D.T.7
-
8
-
-
0027053487
-
Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro
-
Pepper, M. S., Ferrara, N., Orci, L., and Montesano, R. Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro. Biochern. Biophys. Res. Commun., 189: 824-831, 1992.
-
(1992)
Biochern. Biophys. Res. Commun.
, vol.189
, pp. 824-831
-
-
Pepper, M.S.1
Ferrara, N.2
Orci, L.3
Montesano, R.4
-
9
-
-
0026321129
-
Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells
-
Pepper, M. S., Ferrara, N, Orci, L., and Montesano, R. Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells. Biochem. Biophys. Res. Commun., 181: 902-906, 1991.
-
(1991)
Biochem. Biophys. Res. Commun.
, vol.181
, pp. 902-906
-
-
Pepper, M.S.1
Ferrara, N.2
Orci, L.3
Montesano, R.4
-
10
-
-
0026446859
-
Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells
-
Unemori, E. N., Ferrari, N., Bauer, E. A., and Amento, E. P. Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells. J. Cell. Physiol., 153: 557-562, 1992.
-
(1992)
J. Cell. Physiol.
, vol.153
, pp. 557-562
-
-
Unemori, E.N.1
Ferrari, N.2
Bauer, E.A.3
Amento, E.P.4
-
11
-
-
0031870786
-
Vascular endothelial growth factor increases release of gelatinase A and decreases release of tissue inhibitor of metalloproteinases by microvaseular endothelial cells in vitro
-
Lamoreaux, W. J., Fitzgerald, M. E., Reiner, A., Hasty, K. A., and Charles, S. T. Vascular endothelial growth factor increases release of gelatinase A and decreases release of tissue inhibitor of metalloproteinases by microvaseular endothelial cells in vitro. Microvasc. Res., 55: 29-42, 1998.
-
(1998)
Microvasc. Res.
, vol.55
, pp. 29-42
-
-
Lamoreaux, W.J.1
Fitzgerald, M.E.2
Reiner, A.3
Hasty, K.A.4
Charles, S.T.5
-
12
-
-
0029999603
-
Stimulation of endothelial cell migration by vascular endothelial growth factor through cooperative mechanisms involving the αvβ3 integrin, osteopontin, and thrombin
-
Senger, D. R., Ledbetter, S. R., Claffey, K. P., Papadopoulos-Sergio, A., Perruzzi, C. A., and Detmar, M. Stimulation of endothelial cell migration by vascular endothelial growth factor through cooperative mechanisms involving the αvβ3 integrin, osteopontin, and thrombin. Am. J. Pathol., 149: 293-305, 1996.
-
(1996)
Am. J. Pathol.
, vol.149
, pp. 293-305
-
-
Senger, D.R.1
Ledbetter, S.R.2
Claffey, K.P.3
Papadopoulos-Sergio, A.4
Perruzzi, C.A.5
Detmar, M.6
-
13
-
-
0031459892
-
Angiogenesis promoted by vascular endothelial growth factor: Regulation through α1β1 and α2α2 integrins
-
Senger, D. R., Claffey, K. P., Benes, J. E., Perruzzi, C. A., Sergiou, A. P., and Detmar, M. Angiogenesis promoted by vascular endothelial growth factor: regulation through α1β1 and α2α2 integrins. Proc. Natl. Acad. Sci. USA, 94: 13612-13617, 1997.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 13612-13617
-
-
Senger, D.R.1
Claffey, K.P.2
Benes, J.E.3
Perruzzi, C.A.4
Sergiou, A.P.5
Detmar, M.6
-
14
-
-
0029047695
-
Vascular permeability factor/vascular endothelial growth factor an important mediator of angiogenesis in malignancy and inflammation
-
Dvorak, H. F., Detmar, M., Claffey, K. P., Nagy, J. A., van de Water, L., and Senger, D. R. Vascular permeability factor/vascular endothelial growth factor an important mediator of angiogenesis in malignancy and inflammation. Int. Arch. Allergy Appl. Immunol., 107: 233-235, 1995.
-
(1995)
Int. Arch. Allergy Appl. Immunol.
, vol.107
, pp. 233-235
-
-
Dvorak, H.F.1
Detmar, M.2
Claffey, K.P.3
Nagy, J.A.4
Van De Water, L.A.5
Senger, D.R.6
-
15
-
-
0031045279
-
Neovasculature induced by vascular endothelial growth factor is fenestrated
-
Roberts, W. G., and Palade, G. E. Neovasculature induced by vascular endothelial growth factor is fenestrated. Cancer Res., 57: 765-772, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 765-772
-
-
Roberts, W.G.1
Palade, G.E.2
-
16
-
-
0026673043
-
Platelet-derived growth factor-induced transcription of the vascular endothelial growth factor gene is mediated by protein kinase C
-
Finkenzeller, G., Marmé, D., Weich, H. A., and Hug, H. Platelet-derived growth factor-induced transcription of the vascular endothelial growth factor gene is mediated by protein kinase C. Cancer Res., 52: 4821-4823, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 4821-4823
-
-
Finkenzeller, G.1
Marmé, D.2
Weich, H.A.3
Hug, H.4
-
17
-
-
0028221238
-
Vascular endothelial growth factor is induced in response to transforming growth factor-β in fibroblastic and epithelial cells
-
Pertovaara, L., Kaipainen, A., Mustonen, T., Orpana, A., Ferrara, N., Saksela, O., and Alitalo, K. Vascular endothelial growth factor is induced in response to transforming growth factor-β in fibroblastic and epithelial cells. J. Biol. Chem., 269: 6271-6274, 1994.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 6271-6274
-
-
Pertovaara, L.1
Kaipainen, A.2
Mustonen, T.3
Orpana, A.4
Ferrara, N.5
Saksela, O.6
Alitalo, K.7
-
18
-
-
0030046481
-
Interleukin 6 induces the expression of vascular endothelial growth factor
-
Cohen, T., Nahari, D., Cerem, L. W., Neufeld, G., and Levi, B. Z. Interleukin 6 induces the expression of vascular endothelial growth factor. J. Biol. Chem., 271: 736-741, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 736-741
-
-
Cohen, T.1
Nahari, D.2
Cerem, L.W.3
Neufeld, G.4
Levi, B.Z.5
-
19
-
-
0028870050
-
Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids-implications for tumour angiogenesis
-
Shweiki, D., Neeman, M., Itin, A., and Keshet, E. Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids-implications for tumour angiogenesis. Proc. Natl. Acad. Sci. USA, 92: 768-772, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 768-772
-
-
Shweiki, D.1
Neeman, M.2
Itin, A.3
Keshet, E.4
-
20
-
-
0028822834
-
Mutant ras oncogenes upregulate VEGF/VPF expression: Implications for induction and inhibition of tumour angiogenesis
-
Rak, J., Mitsuhashi, L., Bayo, L., Filmus, J., Shirasawa, S., Sasazuki, T., and Kerbel, R. S. Mutant ras oncogenes upregulate VEGF/VPF expression: implications for induction and inhibition of tumour angiogenesis. Cancer Res., 55: 4575-4580, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 4575-4580
-
-
Rak, J.1
Mitsuhashi, L.2
Bayo, L.3
Filmus, J.4
Shirasawa, S.5
Sasazuki, T.6
Kerbel, R.S.7
-
21
-
-
0028834638
-
Both v-Ha-Ras and v-Raf stimulate expression of the vascular endothelial growth factor in NIH 3T3 cells
-
Grugel, S., Finkenzeller, G., Weindel, K., Barleon, B., and Marme, D. Both v-Ha-Ras and v-Raf stimulate expression of the vascular endothelial growth factor in NIH 3T3 cells. J. Biol. Chem., 270: 25915-25919, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 25915-25919
-
-
Grugel, S.1
Finkenzeller, G.2
Weindel, K.3
Barleon, B.4
Marme, D.5
-
22
-
-
0029068339
-
Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation
-
Lond.
-
Mukhopadhyay, D., Tsiokas, L., Zhou, X-M., Foster, D., Brugge, J. S., and Sukhatme, V. P. Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation. Nature (Lond.), 375: 577-580, 1995.
-
(1995)
Nature
, vol.375
, pp. 577-580
-
-
Mukhopadhyay, D.1
Tsiokas, L.2
Zhou, X.-M.3
Foster, D.4
Brugge, J.S.5
Sukhatme, V.P.6
-
23
-
-
0029150852
-
c-fos is required for malignant progression for skin tumours
-
Saez, E., Rutberg, S. E., Mueller, E., Oppenheim, H., Smoluk, J., Yuspa, S. H., and Spiegelman, B. M. c-fos is required for malignant progression for skin tumours. Cell, 82: 721-732, 1995.
-
(1995)
Cell
, vol.82
, pp. 721-732
-
-
Saez, E.1
Rutberg, S.E.2
Mueller, E.3
Oppenheim, H.4
Smoluk, J.5
Yuspa, S.H.6
Spiegelman, B.M.7
-
24
-
-
0028865988
-
Wild-type p53 and v-Src exert opposing influences on human vascular endothelial growth factor gene expression
-
Mukhopadhyay, D., Tsiokas, L., and Sukhatme, V. P. Wild-type p53 and v-Src exert opposing influences on human vascular endothelial growth factor gene expression. Cancer Res., 55: 6161-6165, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 6161-6165
-
-
Mukhopadhyay, D.1
Tsiokas, L.2
Sukhatme, V.P.3
-
25
-
-
0030806074
-
Up-regulation of vascular endothelial growth factor expression in a rat glioma is conferred by two distinct hypoxia-driven mechanisms
-
Damert, A., Machein, M., Breier, G., Fujita, M. Q., Hanahan, D., Risau, W., and Plate, K. H. Up-regulation of vascular endothelial growth factor expression in a rat glioma is conferred by two distinct hypoxia-driven mechanisms. Cancer Res., 57: 3860-3864, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 3860-3864
-
-
Damert, A.1
Machein, M.2
Breier, G.3
Fujita, M.Q.4
Hanahan, D.5
Risau, W.6
Plate, K.H.7
-
26
-
-
0032941747
-
Hypoxic regulation of vascular endothelial growth factor mRNA stability requires the cooperation of multiple RNA elements
-
Dibbens, J. A., Miller, D. L., Damert, A., Risau, W., Vadas, M. A., and Goodall, G. J. Hypoxic regulation of vascular endothelial growth factor mRNA stability requires the cooperation of multiple RNA elements. Mol. Biol. Cell, 10: 907-919, 1999.
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 907-919
-
-
Dibbens, J.A.1
Miller, D.L.2
Damert, A.3
Risau, W.4
Vadas, M.A.5
Goodall, G.J.6
-
27
-
-
0027298573
-
Characterisation of vascular-permeability factor/vascular endothelial growth factor receptors on mononuclear phagocytes
-
Shen, H., Clauss, M., Ryan, J., Schmidt, A. M., Tijburg, P., Borden, L., Connolly, D., Stem, D., and Kao, J. Characterisation of vascular-permeability factor/vascular endothelial growth factor receptors on mononuclear phagocytes. Blood, 81: 2767-2773, 1993.
-
(1993)
Blood
, vol.81
, pp. 2767-2773
-
-
Shen, H.1
Clauss, M.2
Ryan, J.3
Schmidt, A.M.4
Tijburg, P.5
Borden, L.6
Connolly, D.7
Stem, D.8
Kao, J.9
-
28
-
-
0032932547
-
Vascular endothelial growth factor acts, as a pericyte mitogen under hypoxic conditions
-
Yarnagishi, S., Yonekura, H., Yamamoto, Y., Fujimori, H., Sakurai, S., Tanaka, N., and Yamamoto, H. Vascular endothelial growth factor acts, as a pericyte mitogen under hypoxic conditions. Lab. Investig., 79: 501-509, 1999.
-
(1999)
Lab. Investig.
, vol.79
, pp. 501-509
-
-
Yarnagishi, S.1
Yonekura, H.2
Yamamoto, Y.3
Fujimori, H.4
Sakurai, S.5
Tanaka, N.6
Yamamoto, H.7
-
29
-
-
0032547763
-
Vascular endothelial growth factor upregulates the expression of matrix metalloproteinases in vascular smooth muscle cells: Role of Flt-I
-
Wang, H., and Keiser, J. A. Vascular endothelial growth factor upregulates the expression of matrix metalloproteinases in vascular smooth muscle cells: role of Flt-I. Circ. Res., 83: 832-840, 1998.
-
(1998)
Circ. Res.
, vol.83
, pp. 832-840
-
-
Wang, H.1
Keiser, J.A.2
-
30
-
-
0028090642
-
Vascular endothelial growth factor and glioma angiogenesis: Coordinate induction of VEGF receptors, distribution of VEGF protein and possible in vivo regulatory mechanisms
-
Plate, K H., Breier, G., Weich, H. A., Mennel, H. D., and Risau, W. Vascular endothelial growth factor and glioma angiogenesis: coordinate induction of VEGF receptors, distribution of VEGF protein and possible in vivo regulatory mechanisms. Int. J. Cancer, 59: 520-529, 1994.
-
(1994)
Int. J. Cancer
, vol.59
, pp. 520-529
-
-
Plate, K.H.1
Breier, G.2
Weich, H.A.3
Mennel, H.D.4
Risau, W.5
-
31
-
-
0032080310
-
Requirements for binding and signaling of the kinase domain receptor for vascular endothelial growth factor
-
Fuh, G., Li, B., Crowley, C., Cunningham, B., and Wells, J. A. Requirements for binding and signaling of the kinase domain receptor for vascular endothelial growth factor. J. Biol. Chem., 273: 11197-11204, 1998.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 11197-11204
-
-
Fuh, G.1
Li, B.2
Crowley, C.3
Cunningham, B.4
Wells, J.A.5
-
33
-
-
0033118228
-
VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells
-
Takahashi, T., Ueno, H., and Shibuya, M. VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells. Oncogene, 18: 2221-2230, 1999.
-
(1999)
Oncogene
, vol.18
, pp. 2221-2230
-
-
Takahashi, T.1
Ueno, H.2
Shibuya, M.3
-
34
-
-
0030734010
-
p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells
-
Rousseau. S., Houle, F., Landry, J., and Huoi, J. p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells. Oncogene, 15: 2169-2177, 1997.
-
(1997)
Oncogene
, vol.15
, pp. 2169-2177
-
-
Rousseau, S.1
Houle, F.2
Landry, J.3
Huoi, J.4
-
35
-
-
0030908042
-
Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells
-
Abedi, H., and Zachary, I. Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells. J. Biol. Chem., 272: 15442-15451, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 15442-15451
-
-
Abedi, H.1
Zachary, I.2
-
36
-
-
0027197245
-
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
-
Lond.
-
Kim, K. J., Li, B., Winer, J., Armanini, M., Gillett, N., Phillips, H. S., and Ferrara, N. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature (Lond.), 362: 841-844, 1993.
-
(1993)
Nature
, vol.362
, pp. 841-844
-
-
Kim, K.J.1
Li, B.2
Winer, J.3
Armanini, M.4
Gillett, N.5
Phillips, H.S.6
Ferrara, N.7
-
37
-
-
0031870765
-
Anti-tumour and anti-melastatic effects of human-vascular-endothelial-growth-factor-neutralizing antibody on human colon and gastric carcinoma xenotransplanted ortholopically into nude mice
-
Kanai. T., Konno, H., Tanaka, T., Baba, M., Matsumoto, K., Nakamura, S., Yukita, A., Asano, M., Suzuki, H., and Baba, S. Anti-tumour and anti-melastatic effects of human-vascular-endothelial-growth-factor-neutralizing antibody on human colon and gastric carcinoma xenotransplanted ortholopically into nude mice. Int. J. Cancer, 77: 933-936, 1998.
-
(1998)
Int. J. Cancer
, vol.77
, pp. 933-936
-
-
Kanai, T.1
Konno, H.2
Tanaka, T.3
Baba, M.4
Matsumoto, K.5
Nakamura, S.6
Yukita, A.7
Asano, M.8
Suzuki, H.9
Baba, S.10
-
38
-
-
0032145315
-
Inhibition of vascular endothelial growth factor-induced receptor activation with anti-kinase insert domain-containing receptor single chain antibodies from a phage display library
-
Zhu, Z., Rockwell, P., Lu, D., Kotanides, H., Pytowski, B., Hicklin, D. J., Bohlen, P., and Witte, L. Inhibition of vascular endothelial growth factor-induced receptor activation with anti-kinase insert domain-containing receptor single chain antibodies from a phage display library. Cancer Res., 58: 3209-3214, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 3209-3214
-
-
Zhu, Z.1
Rockwell, P.2
Lu, D.3
Kotanides, H.4
Pytowski, B.5
Hicklin, D.J.6
Bohlen, P.7
Witte, L.8
-
39
-
-
0032515980
-
An antagonistic vascular endothelial growth factor (VEGF) variant inhibits VEGF-stimulated receptor autophosphorylation and proliferation of human endothelial cells
-
Siemeister, G., Schimer, M., Reusch, P., Barleon, B., Marme, D., and Martiny-Baron, G. An antagonistic vascular endothelial growth factor (VEGF) variant inhibits VEGF-stimulated receptor autophosphorylation and proliferation of human endothelial cells. Proc. Natl. Acad. Sci. USA, 95: 4625-4629, 1998.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 4625-4629
-
-
Siemeister, G.1
Schimer, M.2
Reusch, P.3
Barleon, B.4
Marme, D.5
Martiny-Baron, G.6
-
40
-
-
0031965353
-
Inhibition of tumour growth by targeting tumour endothelium using a soluble vascular endothelial growth factor receptor
-
Lin, P., Sankar, S., Shan, S., Dewhirst, M. W., Polverini, P. J., Quinn, T. Q., and Peters, K. G. Inhibition of tumour growth by targeting tumour endothelium using a soluble vascular endothelial growth factor receptor. Cell Growth Differ., 9: 49-58, 1998.
-
(1998)
Cell Growth Differ.
, vol.9
, pp. 49-58
-
-
Lin, P.1
Sankar, S.2
Shan, S.3
Dewhirst, M.W.4
Polverini, P.J.5
Quinn, T.Q.6
Peters, K.G.7
-
41
-
-
0029782859
-
Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor
-
Cheng, S-Y., Huang, H-J, S., Nagane, M., Ji, X-D., Wang, D., Shin, C. C-Y., Arap, W., Huang, C-M., and Cavenee, W. K. Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor. Proc. Natl. Acad. Sci. USA, 93: 8502-8507, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 8502-8507
-
-
Cheng, S.-Y.1
Huang, H.-J.S.2
Nagane, M.3
Ji, X.-D.4
Wang, D.5
Shin, C.C.-Y.6
Arap, W.7
Huang, C.-M.8
Cavenee, W.K.9
-
42
-
-
0029863730
-
Dominant-negative inhibition of Flk-1 suppresses the growth of many tumour types in vivo
-
Millauer, B., Longhi, M. P., Plate, K. H., Shawver, L. K., Risau, W., Ullrich, A., and Strawn, L. M. Dominant-negative inhibition of Flk-1 suppresses the growth of many tumour types in vivo. Cancer Res., 56: 1615-1620, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 1615-1620
-
-
Millauer, B.1
Longhi, M.P.2
Plate, K.H.3
Shawver, L.K.4
Risau, W.5
Ullrich, A.6
Strawn, L.M.7
-
43
-
-
0042966942
-
A novel approach to glioma gene therapy: Down-regulation of the vascular endothelial growth factor in glioma cells using ribozymes
-
Ke, L. D., Fueyo, J., Chen, X., Steck, P. A., Shi, Y-X., Im, A-A., and Yung, W. K. A. A novel approach to glioma gene therapy: down-regulation of the vascular endothelial growth factor in glioma cells using ribozymes. Int. J. Oncol., 12: 1391-1396, 1998.
-
(1998)
Int. J. Oncol.
, vol.12
, pp. 1391-1396
-
-
Ke, L.D.1
Fueyo, J.2
Chen, X.3
Steck, P.A.4
Shi, Y.-X.5
Im, A.-A.6
Yung, W.K.A.7
-
44
-
-
17544387877
-
Design and structure-activity relationship of a new class of potent VEGF receptor lyrosine kinase inhibitors
-
Hennequin, L. F., Thomas, A. P., Johnstone, C., Stokes, E. S. E., Plé. P. A., Lohmann, J. M., Ogilvie, D. J., Dukes, M., Wedge, S. R., Curwen, J. O., Kendrew, J., and Lambert-van der Brempt, C. Design and structure-activity relationship of a new class of potent VEGF receptor lyrosine kinase inhibitors. J. Med. Chem., 42: 5369-5389, 1999.
-
(1999)
J. Med. Chem.
, vol.42
, pp. 5369-5389
-
-
Hennequin, L.F.1
Thomas, A.P.2
Johnstone, C.3
Stokes, E.S.E.4
Plé, P.A.5
Lohmann, J.M.6
Ogilvie, D.J.7
Dukes, M.8
Wedge, S.R.9
Curwen, J.O.10
Kendrew, J.11
Lambert-Van Der Brempt, C.12
-
45
-
-
0033027858
-
VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation
-
Gerber, H-P., Vu, T. H., Ryan, A. M., Kowalski, J., Werb, Z., and Ferrara, N. VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation. Nat. Med., 5: 623-628, 1999.
-
(1999)
Nat. Med.
, vol.5
, pp. 623-628
-
-
Gerber, H.-P.1
Vu, T.H.2
Ryan, A.M.3
Kowalski, J.4
Werb, Z.5
Ferrara, N.6
-
46
-
-
85027609620
-
The structural aspects of vascular invasion of the tibial epiphyscal plate of growing rats
-
Schenk, R. K., Weiner, J., and Shapiro, D. The structural aspects of vascular invasion of the tibial epiphyscal plate of growing rats. Acta Anat., 68: 1-17, 1968.
-
(1968)
Acta Anat.
, vol.68
, pp. 1-17
-
-
Schenk, R.K.1
Weiner, J.2
Shapiro, D.3
-
47
-
-
0032790417
-
Immunolocalisation of vascular endothelial growth factor (VEGF) in human neonatal growth plale cartilage
-
Homer, A., Bishop, N. J., Bord, S., Beeton, C., Kelsall, A. W., Coleman, N., and Compston, J. E. Immunolocalisation of vascular endothelial growth factor (VEGF) in human neonatal growth plale cartilage. J. Anat., 194: 519-524, 1999.
-
(1999)
J. Anat.
, vol.194
, pp. 519-524
-
-
Homer, A.1
Bishop, N.J.2
Bord, S.3
Beeton, C.4
Kelsall, A.W.5
Coleman, N.6
Compston, J.E.7
-
48
-
-
0032979775
-
Preclinical safety evaluation of rbuMAbVEGF, an antiangiogenic humanised monoclonal antibody
-
Ryan, A. M., Eppler, D. B., Hagler, K. E., Bruner, R. H., Thomford, P. J., Hall, R. L., Shopp, G. M., and O'Niell, C. A. Preclinical safety evaluation of rbuMAbVEGF, an antiangiogenic humanised monoclonal antibody. Toxicol, Pathol., 27: 78-86, 1999.
-
(1999)
Toxicol, Pathol.
, vol.27
, pp. 78-86
-
-
Ryan, A.M.1
Eppler, D.B.2
Hagler, K.E.3
Bruner, R.H.4
Thomford, P.J.5
Hall, R.L.6
Shopp, G.M.7
O'Niell, C.A.8
-
49
-
-
0029816983
-
Complete inhibition of angiogenesis and growth of microtumours by anti-vascular endothelial growth factor neutralizing antibodies. Novel concepts of angiostatic therapy from intravital videomicroscopy
-
Borgström, P., Hillan, K. J., Sriramarao, P., and Ferrara, N. Complete inhibition of angiogenesis and growth of microtumours by anti-vascular endothelial growth factor neutralizing antibodies. Novel concepts of angiostatic therapy from intravital videomicroscopy. Cancer Res., 56: 4032-4039, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 4032-4039
-
-
Borgström, P.1
Hillan, K.J.2
Sriramarao, P.3
Ferrara, N.4
-
50
-
-
0032893263
-
SU5416 is a potent and selective inhibitor of the vascular cndothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumour vascularisation, and growth of multiple tumour types
-
Fong, T. A., Shawver, L. K., Sun, L., Tang, C., App, H., Powell, J., Kim, Y. H., Schreck, R., Wang, X., Risau, W., Ullrich, A., Hirth, P., and McMahon, G. SU5416 is a potent and selective inhibitor of the vascular cndothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumour vascularisation, and growth of multiple tumour types. Cancer Res., 59: 99-106, 1999.
-
(1999)
Cancer Res.
, vol.59
, pp. 99-106
-
-
Fong, T.A.1
Shawver, L.K.2
Sun, L.3
Tang, C.4
App, H.5
Powell, J.6
Kim, Y.H.7
Schreck, R.8
Wang, X.9
Risau, W.10
Ullrich, A.11
Hirth, P.12
McMahon, G.13
-
51
-
-
0027997863
-
Different signal transduction properties of KDR and Flt-1: Two receptors for vascular endothelial growth factor
-
Waltenberger, J., Claesson-Welsh, L., Siegbahn, A., Shibuya, M., and Heldin, C-H. Different signal transduction properties of KDR and Flt-1: two receptors for vascular endothelial growth factor. J. Biol. Chem., 269: 26988-26995, 1994.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 26988-26995
-
-
Waltenberger, J.1
Claesson-Welsh, L.2
Siegbahn, A.3
Shibuya, M.4
Heldin, C.-H.5
-
52
-
-
0026092346
-
Specific binding of vascular permeability factor to endothelial cells
-
Olander, J. V., Connolly, D. T., and DeLarco, J. E. Specific binding of vascular permeability factor to endothelial cells. Biochem. Biophys. Res. Commun., 175: 68-76, 1991.
-
(1991)
Biochem. Biophys. Res. Commun.
, vol.175
, pp. 68-76
-
-
Olander, J.V.1
Connolly, D.T.2
DeLarco, J.E.3
-
53
-
-
0031577563
-
The phosphorylated 1169-tyrosine containing region of flt-1 kinase (VEGFR-1) is a major binding site for PLCγ
-
Sawano, A., Takahashi, T., Yamaguchi, S., and Shibuya, M. The phosphorylated 1169-tyrosine containing region of flt-1 kinase (VEGFR-1) is a major binding site for PLCγ. Biochem. Biophys. Res. Commun., 238: 487-491, 1997.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.238
, pp. 487-491
-
-
Sawano, A.1
Takahashi, T.2
Yamaguchi, S.3
Shibuya, M.4
-
54
-
-
0030701960
-
Halting angiogenesis suppresses carcinoma cell invasion
-
Skobe, M., Rockwell, P., Goldstein, N., Vosseler, S., and Fusenig, N. E. Halting angiogenesis suppresses carcinoma cell invasion. Nat. Med., 3: 1222-1227, 1997.
-
(1997)
Nat. Med.
, vol.3
, pp. 1222-1227
-
-
Skobe, M.1
Rockwell, P.2
Goldstein, N.3
Vosseler, S.4
Fusenig, N.E.5
-
55
-
-
0344637004
-
Systemic activation of the vascular endothelial growth factor receptor KDR/flk-1 selectively triggers endothelial cells with an angiogenic phenotype
-
Ortéga, N., Jonca, F., Vincent, S., Favard, C., Ruchoux, M-M., and Plouët, J. Systemic activation of the vascular endothelial growth factor receptor KDR/flk-1 selectively triggers endothelial cells with an angiogenic phenotype. Am. J. Pathol., 151: 1215-1224, 1997
-
(1997)
Am. J. Pathol.
, vol.151
, pp. 1215-1224
-
-
Ortéga, N.1
Jonca, F.2
Vincent, S.3
Favard, C.4
Ruchoux, M.-M.5
Plouët, J.6
-
56
-
-
0032553299
-
A novel type of vascular endothelial growth factor, VEGF-E (NZ-7 VEGF), preferentially utilizes KDR/Flk-1 receptor and carries a potent mitotic activity without heparin-binding domain
-
Ogawa, S., Oku, A., Sawano, A., Yamaguchi, S., Yazaki, Y., and Shibuya, M. A novel type of vascular endothelial growth factor, VEGF-E (NZ-7 VEGF), preferentially utilizes KDR/Flk-1 receptor and carries a potent mitotic activity without heparin-binding domain. J. Biol. Chem., 273: 31273-31282, 1998.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 31273-31282
-
-
Ogawa, S.1
Oku, A.2
Sawano, A.3
Yamaguchi, S.4
Yazaki, Y.5
Shibuya, M.6
-
57
-
-
0028134936
-
Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity in vitro and in vivo and high affinity binding to Flt-1 but not to Flk-1/KDR
-
Park, J. E., Chen, H. H., Winer, J., Houck, A. A., and Ferrara, N. J. Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity in vitro and in vivo and high affinity binding to Flt-1 but not to Flk-1/KDR. J. Biol. Chem., 269: 25646-25654, 1994.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 25646-25654
-
-
Park, J.E.1
Chen, H.H.2
Winer, J.3
Houck, A.A.4
Ferrara, N.J.5
-
58
-
-
0033556287
-
A novel vascular endothelial growth factor encoded by Orf virus, VEGF-E, mediates angiogenesis via signalling through VEGFR-2 (KDR) but not VEGFR-1 (Flt-1 ) receptor tyrosine kinase
-
Meyer, M., Clauss, M., Lepple-Wienhues, A., Waltenberger, J., Augustin, H. G., Ziche, M., Lanz, C., Büttner, M., Rziha, H-J., and Dehio, C. A novel vascular endothelial growth factor encoded by Orf virus, VEGF-E, mediates angiogenesis via signalling through VEGFR-2 (KDR) but not VEGFR-1 (Flt-1 ) receptor tyrosine kinase. EMBO J., 18: 363-374, 1999.
-
(1999)
EMBO J.
, vol.18
, pp. 363-374
-
-
Meyer, M.1
Clauss, M.2
Lepple-Wienhues, A.3
Waltenberger, J.4
Augustin, H.G.5
Ziche, M.6
Lanz, C.7
Büttner, M.8
Rziha, H.-J.9
Dehio, C.10
-
59
-
-
0027432324
-
Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumour angiogenesis
-
Plate, K. H., Breier, G., Millauer, B., Ullrich, A., and Risau, W. Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumour angiogenesis. Cancer Res., 53: 5822-5827, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 5822-5827
-
-
Plate, K.H.1
Breier, G.2
Millauer, B.3
Ullrich, A.4
Risau, W.5
-
60
-
-
84970070220
-
Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer
-
Takahashi, Y., Kitadal, Y., Bucana, C. D., Cleary, K. R., and Ellis, L. M. Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer. Cancer Res., 55: 3964-3968, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 3964-3968
-
-
Takahashi, Y.1
Kitadal, Y.2
Bucana, C.D.3
Cleary, K.R.4
Ellis, L.M.5
-
61
-
-
0032482978
-
Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice
-
Hiratsuka, S., Minowa, O., Kuno, J., Noda, T., and Shibuya, M. Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice. Proc. Natl. Acad. Sci. USA, 95: 9349-9354, 1998.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 9349-9354
-
-
Hiratsuka, S.1
Minowa, O.2
Kuno, J.3
Noda, T.4
Shibuya, M.5
-
62
-
-
0029021660
-
Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
-
Lond.
-
Fong, G-H., Rossant, J., Gertsenstein, M., and Breitman, M. L. Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature (Lond.), 376: 66-70, 1995.
-
(1995)
Nature
, vol.376
, pp. 66-70
-
-
Fong, G.-H.1
Rossant, J.2
Gertsenstein, M.3
Breitman, M.L.4
-
63
-
-
0032556950
-
Placenta growth factor stimulates MAP kinase and mitogenicity but not phospholipase C-γ and migration of endothelial cells expressing Flt 1
-
Landgren, E., Schiller, P., Cao, Y., and Claesson-Welsh, L. Placenta growth factor stimulates MAP kinase and mitogenicity but not phospholipase C-γ and migration of endothelial cells expressing Flt 1. Oncogene, 16: 359-367, 1998.
-
(1998)
Oncogene
, vol.16
, pp. 359-367
-
-
Landgren, E.1
Schiller, P.2
Cao, Y.3
Claesson-Welsh, L.4
-
64
-
-
0029867554
-
Migration of human monocytes in response to human vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1
-
Barleon, B., Sozzani, S., Zhou, D., Weich, H. A., Mantovani, A., and Marmé, D. Migration of human monocytes in response to human vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1. Blood, 87: 3336-3343, 1996.
-
(1996)
Blood
, vol.87
, pp. 3336-3343
-
-
Barleon, B.1
Sozzani, S.2
Zhou, D.3
Weich, H.A.4
Mantovani, A.5
Marmé, D.6
-
65
-
-
0029929716
-
The vascular endothelial growth factor receptor Flt-1 mediates biological activities
-
Clauss, M., Weich, H., Breier, G., Knies, U., Rockl, W., Waltenberger, J., and Risau, W. The vascular endothelial growth factor receptor Flt-1 mediates biological activities. J. Biol. Chem., 30: 17629-17634, 1996.
-
(1996)
J. Biol. Chem.
, vol.30
, pp. 17629-17634
-
-
Clauss, M.1
Weich, H.2
Breier, G.3
Knies, U.4
Rockl, W.5
Waltenberger, J.6
Risau, W.7
-
66
-
-
0031892785
-
Vascular endothelial growth factor affects dendritic cell maturation through the inhibition of nuclear factor-KκB activation in hemopoietic progenitor cells
-
Oyama, T., Ran, S., Ishida, T., Nadaf, S., Kerr, W., Carbone, D. P., and Gabrilovich, D. I. Vascular endothelial growth factor affects dendritic cell maturation through the inhibition of nuclear factor-KκB activation in hemopoietic progenitor cells. J. Immunol., 160: 1224-1232, 1998.
-
(1998)
J. Immunol.
, vol.160
, pp. 1224-1232
-
-
Oyama, T.1
Ran, S.2
Ishida, T.3
Nadaf, S.4
Kerr, W.5
Carbone, D.P.6
Gabrilovich, D.I.7
-
67
-
-
0031757269
-
The vascular endothelial growth factor family: Proteins which guide the development of the vasculature
-
Achen, M. G., and Stacker, S. A. The vascular endothelial growth factor family: proteins which guide the development of the vasculature. Int. J. Exp. Pathol., 79: 255-265, 1998.
-
(1998)
Int. J. Exp. Pathol.
, vol.79
, pp. 255-265
-
-
Achen, M.G.1
Stacker, S.A.2
-
68
-
-
0028803509
-
Vascular endothelial factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity
-
Alon, T., Hemo, I., Itin, A., Pe'ee, J., Stone, J., and Keshet, E. Vascular endothelial factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity. Nat. Med., 1: 1024-1028, 1995.
-
(1995)
Nat. Med.
, vol.1
, pp. 1024-1028
-
-
Alon, T.1
Hemo, I.2
Itin, A.3
Pe'ee, J.4
Stone, J.5
Keshet, E.6
-
69
-
-
0032952010
-
Selective ablation of immature blood vessels in established human tumours follows vascular endothelial growth factor withdrawal
-
Benjamin, L. E., Golijanin, D., Itin, A., Pode, D., and Keshet, E. Selective ablation of immature blood vessels in established human tumours follows vascular endothelial growth factor withdrawal. J. Clin. Investig., 103: 159-165, 1999.
-
(1999)
J. Clin. Investig.
, vol.103
, pp. 159-165
-
-
Benjamin, L.E.1
Golijanin, D.2
Itin, A.3
Pode, D.4
Keshet, E.5
-
70
-
-
0032963472
-
Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression
-
Nör, J. E., Christensen, J., Mooney, D. J., and Polverini, P. J. Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression. Am. J. Pathol., 154: 375-384, 1999.
-
(1999)
Am. J. Pathol.
, vol.154
, pp. 375-384
-
-
Nör, J.E.1
Christensen, J.2
Mooney, D.J.3
Polverini, P.J.4
-
71
-
-
0001416170
-
Effect of the VEGF receptor tyrosine kinase inhibitor ZD4190 on vascular endothelial permeability
-
Wedge, S. R., Waterton, J. C., Tessier, J. J., Checkley, D., Dukes, M., Kendrew, J., and Curry, B. Effect of the VEGF receptor tyrosine kinase inhibitor ZD4190 on vascular endothelial permeability. Proc. Am. Assoc. Cancer Res., 40: 2741, 1999.
-
(1999)
Proc. Am. Assoc. Cancer Res.
, vol.40
, pp. 2741
-
-
Wedge, S.R.1
Waterton, J.C.2
Tessier, J.J.3
Checkley, D.4
Dukes, M.5
Kendrew, J.6
Curry, B.7
-
72
-
-
0028199835
-
Vascular endothelial growth factor: A cytokine modulating endothelial function in rheumatoid arthritis
-
Koch, A. E., Harlow, L. A., Haines, G. K., Amento, E. P., Unemori, E. N., Wong, W. L., Pope, R. M., and Ferrara, N. Vascular endothelial growth factor: a cytokine modulating endothelial function in rheumatoid arthritis. J. Immunol., 152: 149-152, 1994.
-
(1994)
J. Immunol.
, vol.152
, pp. 149-152
-
-
Koch, A.E.1
Harlow, L.A.2
Haines, G.K.3
Amento, E.P.4
Unemori, E.N.5
Wong, W.L.6
Pope, R.M.7
Ferrara, N.8
-
73
-
-
0028123090
-
Increased endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy
-
Adamis, A. P., Increased endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy. Am. J. Ophthalmol., 118: 445-450, 1994.
-
(1994)
Am. J. Ophthalmol.
, vol.118
, pp. 445-450
-
-
Adamis, A.P.1
|