Effect of in situ retroviral interleukin-4 transfer on established intracranial tumors

Journal of the National Cancer Institute

Volumn 91, Issue 5, 1999, Pages 438-445

  Saleh, Mary ^a   Wiegmans, Adrian ^a   Malone, Quentin ^a   Stylli, Stan S ^a   Kaye, Andrew H ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 4; VASCULOTROPIN; VASCULOTROPIN RECEPTOR;

ANGIOGENESIS; ANIMAL CELL; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; EOSINOPHIL; GENE TRANSFER; GLIOMA; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; IMMUNOPEROXIDASE STAINING; INTRACRANIAL TUMOR; INTRATUMORAL DRUG ADMINISTRATION; MACROPHAGE; MICROPHOTOGRAPHY; NONHUMAN; PRIORITY JOURNAL; RAT; RETROVIRUS; TUMOR VOLUME;

EID: 0033518887     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/91.5.438     Document Type: Article

References (33)

1. Walker MD, Alexander E Jr, Hunt WEJ, MacCarty CS, Mahaley MS Jr, Mealey J Jr, et al. Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. A cooperative clinical trial. J Neurosurg 1978;49: 333-43.
2. Rosenberg SA, Anderson WF, Asher AL, Blaese MR, Ettinghaussen SE, Hwu P, et al. Immunization of cancer patients using autologous cancer cells modified by insertion of the gene for tumor necrosis factor. Hum Gene Ther 1992;3:57-73.
3. Rosenberg SA, Anderson WF, Blaese MR, Ettinghaussen SE, Hwu P, Karp SE, et al. Immunization of cancer patients using autologous cancer cells modified by insertion of the gene for interleukin-2. Hum Gene Ther 1992;3:75-90.
4. Lyerly HK, DiMaio JM. Gene delivery systems in surgery. Arch Surg 1993;128:1197-206.
5. Watanabe Y. Transfection of interferon-gamma gene in animal tumors - a model for local cytokine production and tumor immunity. Semin Cancer Biol 1992;3:43-6.
6. Watanabe Y, Kuribayashi K, Miyatake S, Nishihara K, Nakayama E, Taniyama T, et al. Exogenous expression of mouse interferon gamma cDNA in mouse neuroblastoma C1300 cells results in reduced tumorigenicity by augmented anti-tumor immunity. Proc Natl Acad Sci USA 1989;86: 9456-60.
7. Bubenik J, Simova J, Jandlova T. Immunotherapy of cancer using local administration of lymphoid cells transformed by IL-2 cDNA and constitutively producing IL-2. Immunol Lett 1990;23:287-92.
8. Tahara H, Zitvogel L, Storkus WJ, Zeh HJ 3rd, McKinney TG, Schreiber RD, et al. Effective eradication of established murine tumors with IL-12 gene therapy using a polycistronic retroviral vector. J Immunol 1995;154: 6466-74.
9. Tepper RI, Pattengale PK, Leder P. Murine interleukin-4 displays potent anti-tumor activity in vivo. Cell 1989;57:503-12.
10. Golumbek PT, Lazenby AJ, Levitsky HI, Jaffee LM, Karasuyama H, Baker M, et al. Treatment of established renal cancer by tumor cells engineered to secrete interleukin-4. Science 1991;254:713-6.
11. Yu JS, Wei MX, Chiocca EA, Martuza RL, Tepper RI. Treatment of glioma by engineered interleukin 4-secreting cells. Cancer Res 1993;53: 3125-8.
12. Tepper RI, Coffman RL, Leder P. An eosinophil-dependent mechanism for the antitumor effect of interleukin-4. Science 1992;257:548-51.
13. Paul WE, Ohara J. B-cell stimulatory factor-1/interleukin 4. Annu Rev Immunol 1987;5:429-59.
14. Howard M, Farrar J, Hilfiker M, Johnson B, Takatsu K, Hamaoka T, et al. Identification of a T cell-derived b cell growth factor distinct from interleukin 2. J Exp Med 1982;155:914-23.
15. Tepper RI. The eosinophil-mediated antitumor activity of interleukin-4. J Allergy Clin Immunol 1994;94:1225-31.
16. Hurford RK Jr, Dranoff G, Mulligan RC, Tepper RI. Gene therapy of metastatic cancer by in vivo retroviral gene targeting. Nat Genet 1995;10: 430-5.
17. Saleh M, Davis ID, Wilks AF. The paracrine role of tumour-derived mIL-4 on tumor-associated endothelium. Int J Cancer 1997;72:664-72.
18. O'Reilly MS, Holmgren L, Chen C, Folkman J. Angiostatin induces and sustains dormancy of human primary tumors in mice. Nat Med 1996;2: 689-92.
19. Saleh M, Stacker SA, Wilks AF. Inhibition of growth of C6 glioma cells in vivo by expression of antisense vascular endothelial growth factor sequence. Cancer Res 1996;56:393-401.
20. Saleh M, Vasilopoulos K, Stylli SS, Kaye AH, Wilks AF. The expression of antisense vascular endothelial growth factor (VEGF) sequences inhibit intracranial glioma growth in vivo by suppressing tumour angiogenesis. J Clin Neurosci 1996;3:366-72.
21. Maher DW, Davis I, Boyd AW, Morstyn G. Human interleukin-4: an immunomodulator with potential therapeutic applications. Prog Growth Factor Res 1991;3:43-56.
22. Markowitz D, Hesdorffer C, Ward M, Goff S, Bank A. Retroviral gene transfer using safe and efficient packaging cell lines. Ann N Y Acad Sci 1990;612:407-14.
23. Saleh M. A retroviral vector that allows efficient co-expression of two genes and the versatility of alternate selection markers. Hum Gene Ther 1997;8:979-83.
24. Lee F, Yokota T, Otsuka T, Meyerson P, Villaret D, Coffman R, et al. Isolation and characterization of a mouse interleukin cDNA clone that expresses B-cell stimulatory factor 1 activities and T-cell- and mast-cell-stimulating activities. Proc Natl Acad Sci U S A 1986;83:2061-5.
25. Mountford P, Zevnik B, Duwel A, Nichols J, Li M, Dani C, et al. Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression. Proc Natl Acad Sci U S A 1994;91:4303-7.
26. Graham FL, Eb AJ van der. Transformation of rat cells by DNA of human adenovirus 5. Virology 1973;54:536-9.
27. Rongish BJ, Hinchman G, Doty MK, Baldwin HS, Tomanek RJ. Relationship of the extracellular matrix to coronary neovascularization during development. J Mol Cell Cardiol 1996;28:2203-15.
28. Williams KC, Zhao RW, Ueno K. Huley WF. PECAM-1 (CD31) expression in the central nervous system and its role in experimental allergic encephalomyelitis in the rat. J Neurosci Res 1996;45:747-57.
29. Ram Z, Culver KW, Oshiro EM, Viola JJ, DeVroom HL, Otto E, et al. Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells. Nat Med 1997;3:1354-61.
30. Oldfield EH, Ram Z, Culver KW, Blaese RM, DeVroom HL, et al. Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovir. Hum Gene Ther 1993;4:39-69.
31. Ram Z, Walbridge S, Shawker T, Culver KW, Blaese RM, Oldfield EH. The effect of thymidine kinase transduction and ganciclovir therapy on tumor vasculature and growth of 9L gliomas in rats. J Neurosurg 1994;81: 256-60.
32. + lymphocyte-driven and eosinophil-mediated rejection of a spontaneous mouse mammary adenocarcinoma engineered to release IL-4. J Immunol 1994;153:5659-73.
33. Wei MX, Tamiya T, Hurford RK Jr, Boviatsis EJ, Tepper RI, Chiocca EA. Enhancement of interleukin-4-mediated tumor regression in athymic mice by in situ retroviral gene transfer. Hum Gene Ther 1995;6:437-43.