Protein-protein coupling/uncoupling enables dopamine D2 receptor regulation of AMPA receptor-mediated excitotoxicity

Journal of Neuroscience

Volumn 25, Issue 17, 2005, Pages 4385-4395

  Zou, Shengwei ^a   Li, Lei ^a   Pei, Lin ^a   Vukusic, Brian ^a   Van Tol, Hubert H M ^a,b   Lee, Frank J S ^a   Wan, Qi ^a,b   Liu, Fang ^a,b,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

Author keywords

AMPA receptors; Cell death; Dopamine receptors; G proteins; NSF; PI 3 kinase; Protein protein interactions

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE 2 RECEPTOR STIMULATING AGENT; GLUTAMATE RECEPTOR 2; N ETHYLMALEIMIDE SENSITIVE FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P85; RECEPTOR SUBUNIT; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL DEATH; CELL MEMBRANE; CONTROLLED STUDY; DISSOCIATION; DRUG TARGETING; EMBRYO; ENZYME ACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; ISCHEMIA; NEUROTOXICITY; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; STROKE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMALS; ANOXIA; APOPTOSIS; BLOTTING, WESTERN; BRAIN; CELLS, CULTURED; DOPAMINE AGONISTS; DOPAMINE ANTAGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; EMBRYO; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXCITATORY AMINO ACID AGONISTS; GABA ANTAGONISTS; GLUCOSE; GLUTATHIONE TRANSFERASE; HUMANS; IMMUNOPRECIPITATION; N-ETHYLMALEIMIDE-SENSITIVE PROTEINS; PICROTOXIN; PROPIDIUM; PROTEIN BINDING; QUINPIROLE; RACLOPRIDE; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTORS, AMPA; RECEPTORS, DOPAMINE D2; RECOMBINANT FUSION PROTEINS;

EID: 18244388958     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5099-04.2005     Document Type: Article

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