Disruption of the GluR2-NSF interaction protects primary hippocampal neurons from ischemic stress

Molecular and Cellular Neuroscience

Volumn 17, Issue 4, 2001, Pages 662-670

  Ralph, G S ^a   Bienemann, A ^a   Ma, J ^a   Tan, H K ^a   Noel, J ^a   Henley, J M ^a   Uney, J B ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMPA RECEPTOR; CALCIUM; HYBRID PROTEIN; KAINIC ACID; N ETHYLMALEIMIDE SENSITIVE FACTOR; RECEPTOR SUBUNIT; UNCLASSIFIED DRUG;

ADENOVIRUS; ANIMAL TISSUE; ARTICLE; BINDING SITE; BRAIN ISCHEMIA; CALCIUM TRANSPORT; HIPPOCAMPUS; NEUROPROTECTION; NEUROTOXICITY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAT;

EID: 0035010474     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1006/mcne.2000.0959     Document Type: Article

References (15)

1. Bennett, M. V., Pellegrini-Giampietro, D. E., Gorter, J. A., Aronica, E., Connor, J. A., and Zukin, R. S. (1996). The GluR2 hypothesis: Ca(++)-permeable AMPA receptors in delayed neurodegeneration. Cold Spring Harb. Symp. Quant. Biol. 61: 373-384.
2. Buchan, A., Li, H., and Pulsinelli, W. A. (1991). The N-methyl-D-aspartate antagonist, MK-801, fails to protect against neuronal damage caused by transient, severe forebrain ischemia in adult rats. J. Neurosci. 11: 1049-1056.
3. Buchan, A. M., Li, H., Cho, S., and Pulsinelli, W. A. (1991). Blockade of the AMPA receptor prevents CA1 hippocampal injury following severe but transient forebrain ischemia in adult rats. Neurosci. Lett. 132: 255-258.
4. Burnashev, N., Monyer, H., Seeburg, P. H., and Sakmann, B. (1992). Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit. Neuron 8: 189-198.
5. Cheng, B., and Mattson, M. P. (1991). NGF and bFGF protect rat hippocampal and human cortical neurons against hypoglycemic damage by stabilizing calcium homeostasis. Neuron 7: 1031-1041.
6. Choi, D. W. (1994). Calcium and excitotoxic neuronal injury. Ann. N.Y. Acad. Sci. 747: 162-171.
7. Choi, D. W., and Rothman, S. M. (1990). The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Annu. Rev. Neurosci. 13: 171-182.
8. Condorelli, D. F., Belluardo, N., Mudo, G., Dell'Albani, P., Jiang, X., and Giuffrida-Stella, A. M. (1994). Changes in gene expression of AMPA-selective glutamate receptor subunits induced by status epilepticus in rat brain. Neurochem. Int. 25: 367-376.
9. Esumi, K., Nishida, M., Shaw, D., Smith, T. W., and Marsh, J. D. (1991). NADH measurements in adult rat myocytes during simulated ischemia. Am. J. Physiol. 260: H1743-H1752.
10. Frank, L., Diemer, N. H., Kaiser, F., Sheardown, M., Rasmussen, J. S., and Kristensen, P. (1995). Unchanged balance between levels of mRNA encoding AMPA glutamate receptor subtypes following global cerebral ischemia in the rat. Acta Neural. Scand. 92: 337-343.
11. Gorter, J. A., Petrozzino, J. J., Aronica, E. M., Rosenbaum, D. M., Opitz, T., Bennett, M. V., Connor, J. A., and Zukin, R. S. (1997). Global ischemia induces downregulation of Glur2 mRNA and increases AMPA receptor-mediated Ca2+ influx in hippocampal CA1 neurons of gerbil. J. Neurosci. 17: 6179-6188.
12. Graham, F. L., and Prevec, L. (1995). Methods for construction of adenovirus vectors. Mol. Biotechnol. 3: 207-220.
13. Grooms, S. Y., Opitz, T., Bennett, M. V., and Zukin, R. S. (2000). Status epilepticus decreases glutamate receptor 2 mRNA and protein ex-pression in hippocampal pyramidal cells before neuronal death. Proc. Null. Acad. Sci. USA 97: 3631-3636.
14. Harding, T. C., Geddes, B. J., Noel, J. D., Murphy, D., and Uney, J. B. (1997). Tetracycline-regulated transgene expression in hippocampal neurones following transfection with adenoviral vectors. J. Neurochem. 69: 2620-2623.
15. Henley, J. M., Nishimune, A., Nash, S. R., and Nakanishi, S. (1997). Use of the two-hybrid system to find novel proteins that interact with alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptor subunits. Biochem. Soc. Trans. 25: 838-842.