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Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 2, 2002, Pages 159-163

The discovery of small molecule carbamates as potent dual α4β1/α4β7 integrin antagonists

(12) Chang, Linda L a Truong, Quang a Mumford, Richard A a Egger, Linda A a Kidambi, Usha a Lyons, Kathryn a McCauley, Ermengilda a Van Riper, Gail a Vincent, Stella a Schmidt, John A a MacCoss, Malcolm a Hagmann, William K a

a MERCK RESEARCH LABORATORIES (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA4BETA1 INTEGRIN ANTAGONIST; ALPHA4BETA7 INTEGRIN; ALPHA4BETA7 INTEGRIN ANTAGONIST; CARBAMIC ACID DERIVATIVE; INTEGRIN; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; VERY LATE ACTIVATION ANTIGEN 4;

ALKYLATION; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG HALF LIFE; DRUG METABOLISM; DRUG POTENCY; IC 50; INFLAMMATION; MOLECULE; NONHUMAN; PLASMA CLEARANCE; RAT; STRUCTURE ACTIVITY RELATION;

CARBAMATES; HUMANS; INTEGRIN ALPHA4BETA1; INTEGRINS; JURKAT CELLS; RECEPTORS, LYMPHOCYTE HOMING; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 18244388008 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/S0960-894X(01)00710-7 Document Type: Article

Times cited : (21)

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