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Volumn 34, Issue 2 SPEC. ISS., 2005, Pages 305-317

Genetics and genotypes in irritable bowel syndrome: Implications for diagnosis and treatment

Author keywords

[No Author keywords available]

Indexed keywords

ALOSETRON; CHOLECYSTOKININ A RECEPTOR ANTAGONIST; DEXLOXIGLUMIDE; SEROTONIN TRANSPORTER;

EID: 18144426823     PISSN: 08898553     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gtc.2005.02.009     Document Type: Review
Times cited : (42)

References (53)
  • 1
    • 0035859198 scopus 로고    scopus 로고
    • The irritable bowel syndrome
    • B.J. Horwitz, and R.S. Fisher The irritable bowel syndrome N Engl J Med 1434 2001 1846 1850
    • (2001) N Engl J Med , vol.1434 , pp. 1846-1850
    • Horwitz, B.J.1    Fisher, R.S.2
  • 2
    • 0033827386 scopus 로고    scopus 로고
    • Familial association in adults with functional gastrointestinal disorders
    • G.R. Locke III, A.R. Zinsmeister, and N.J. Talley Familial association in adults with functional gastrointestinal disorders Mayo Clin Proc 75 2000 907 912
    • (2000) Mayo Clin Proc , vol.75 , pp. 907-912
    • Locke III, G.R.1    Zinsmeister, A.R.2    Talley, N.J.3
  • 3
    • 0032148135 scopus 로고    scopus 로고
    • Evidence of a genetic contribution to functional bowel disorder
    • A. Morris-Yates, N.J. Talley, and P.M. Boyce Evidence of a genetic contribution to functional bowel disorder Am J Gastroenterol 93 1998 1311 1317
    • (1998) Am J Gastroenterol , vol.93 , pp. 1311-1317
    • Morris-Yates, A.1    Talley, N.J.2    Boyce, P.M.3
  • 4
    • 0034788730 scopus 로고    scopus 로고
    • Irritable bowel syndrome in twins: Hereditary and social learning both contribute to etiology
    • R.L. Levy, K.R. Jones, and W.E. Whitehead Irritable bowel syndrome in twins: hereditary and social learning both contribute to etiology Gastroenterology 121 2001 799 804
    • (2001) Gastroenterology , vol.121 , pp. 799-804
    • Levy, R.L.1    Jones, K.R.2    Whitehead, W.E.3
  • 5
    • 0344665564 scopus 로고    scopus 로고
    • Familial aggregation of irritable bowel syndrome: A prospective study
    • J.S. Kalantar, G.R. Locke III, and A.R. Zinsmeister Familial aggregation of irritable bowel syndrome: a prospective study Gut 52 2003 1703 1707
    • (2003) Gut , vol.52 , pp. 1703-1707
    • Kalantar, J.S.1    Locke III, G.R.2    Zinsmeister, A.R.3
  • 6
    • 0038500275 scopus 로고    scopus 로고
    • Genetic influence in irritable bowel syndrome: A twin study
    • I. Mohammed, L. Cherkas, and S.A. Riley Genetic influence in irritable bowel syndrome: a twin study Gut 50 2002 A1
    • (2002) Gut , vol.50 , pp. 1
    • Mohammed, I.1    Cherkas, L.2    Riley, S.A.3
  • 7
    • 0037215492 scopus 로고    scopus 로고
    • Interleukin 10 genotypes in irritable bowel syndrome: Evidence for an inflammatory component?
    • W.M. Gonsalkorale, C. Perrey, and V. Pravica Interleukin 10 genotypes in irritable bowel syndrome: evidence for an inflammatory component? Gut 52 2003 91 93
    • (2003) Gut , vol.52 , pp. 91-93
    • Gonsalkorale, W.M.1    Perrey, C.2    Pravica, V.3
  • 8
    • 4043063354 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha and interleukin 10 gene polymorphisms in irritable bowel syndrome
    • P. Veek, Y. Kroon, and M. Berg Tumor necrosis factor alpha and interleukin 10 gene polymorphisms in irritable bowel syndrome Gastroenterology 126 2004 A52
    • (2004) Gastroenterology , vol.126 , pp. 52
    • Veek, P.1    Kroon, Y.2    Berg, M.3
  • 9
    • 0027528905 scopus 로고
    • Autonomic dysfunction in gastrointestinal motility disorders
    • A.E. Bharucha, M. Camilleri, and P.A. Low Autonomic dysfunction in gastrointestinal motility disorders Gut 34 1993 397 401
    • (1993) Gut , vol.34 , pp. 397-401
    • Bharucha, A.E.1    Camilleri, M.2    Low, P.A.3
  • 10
    • 0028331707 scopus 로고
    • Predominant symptoms in irritable bowel syndrome correlate with specific autonomic nervous system abnormalities
    • A. Aggarwal, T.F. Cutts, and T.L. Abell Predominant symptoms in irritable bowel syndrome correlate with specific autonomic nervous system abnormalities Gastroenterology 106 1994 945 950
    • (1994) Gastroenterology , vol.106 , pp. 945-950
    • Aggarwal, A.1    Cutts, T.F.2    Abell, T.L.3
  • 11
    • 2442677620 scopus 로고    scopus 로고
    • Association of distinct alpha(2) adrenoceptor and serotonin transporter polymorphisms with constipation and somatic symptoms in functional gastrointestinal disorders
    • H.J. Kim, M. Camilleri, and P.J. Carlson Association of distinct alpha(2) adrenoceptor and serotonin transporter polymorphisms with constipation and somatic symptoms in functional gastrointestinal disorders Gut 53 2004 829 837
    • (2004) Gut , vol.53 , pp. 829-837
    • Kim, H.J.1    Camilleri, M.2    Carlson, P.J.3
  • 12
    • 1842583755 scopus 로고    scopus 로고
    • G-protein beta 3 subunit 825 CC genotype is associated with unexplained (functional) dyspepsia
    • G. Holtmann, W. Siffert, and S. Haag G-protein beta 3 subunit 825 CC genotype is associated with unexplained (functional) dyspepsia Gastroenterology 126 2004 971 979
    • (2004) Gastroenterology , vol.126 , pp. 971-979
    • Holtmann, G.1    Siffert, W.2    Haag, S.3
  • 13
    • 0036310957 scopus 로고    scopus 로고
    • Serotonin transporter gene polymorphism in irritable bowel syndrome
    • C. Pata, M.E. Erdal, and E. Derici Serotonin transporter gene polymorphism in irritable bowel syndrome Am J Gastroenterol 97 2002 1780 1784
    • (2002) Am J Gastroenterol , vol.97 , pp. 1780-1784
    • Pata, C.1    Erdal, M.E.2    Derici, E.3
  • 14
    • 4644293513 scopus 로고    scopus 로고
    • Association between a functional polymorphism in the serotonin transporter gene and diarrhea predominant irritable bowel syndrome in women
    • A. Yeo, P. Boyd, and S. Lumsden Association between a functional polymorphism in the serotonin transporter gene and diarrhea predominant irritable bowel syndrome in women Gut 53 2004 1452 1458
    • (2004) Gut , vol.53 , pp. 1452-1458
    • Yeo, A.1    Boyd, P.2    Lumsden, S.3
  • 15
    • 4644226729 scopus 로고    scopus 로고
    • Serotonin transporter gene polymorphism in healthy adults and patients with irritable bowel syndrome
    • D.Y. Lee, H.J. Park, and W.H. Kim Serotonin transporter gene polymorphism in healthy adults and patients with irritable bowel syndrome Korean J Gastroenterol 43 2004 18 22
    • (2004) Korean J Gastroenterol , vol.43 , pp. 18-22
    • Lee, D.Y.1    Park, H.J.2    Kim, W.H.3
  • 16
    • 4344607666 scopus 로고    scopus 로고
    • Inflammation as a basis for functional GI disorders
    • R.C. Spiller Inflammation as a basis for functional GI disorders Best Pract Res Clin Gastroenterol 18 2004 641 661
    • (2004) Best Pract Res Clin Gastroenterol , vol.18 , pp. 641-661
    • Spiller, R.C.1
  • 17
    • 0036038906 scopus 로고    scopus 로고
    • Cytokine imbalance in nonimmunological chronic disease
    • B. Muller Cytokine imbalance in nonimmunological chronic disease Cytokine 18 2002 334 339
    • (2002) Cytokine , vol.18 , pp. 334-339
    • Muller, B.1
  • 18
    • 0021953751 scopus 로고
    • Action of serotonin on the gastrointestinal tract
    • H.S. Ormsbee III, and J.D. Fondacaro Action of serotonin on the gastrointestinal tract Proc Soc Exp Biol Med 178 1985 333 338
    • (1985) Proc Soc Exp Biol Med , vol.178 , pp. 333-338
    • Ormsbee III, H.S.1    Fondacaro, J.D.2
  • 19
    • 0032919084 scopus 로고    scopus 로고
    • Review article: Roles played by 5-hydroxytryptamine in the physiology of the bowel
    • M.D. Gershon Review article: roles played by 5-hydroxytryptamine in the physiology of the bowel Aliment Pharmacol Ther 13 1999 15 30
    • (1999) Aliment Pharmacol Ther , vol.13 , pp. 15-30
    • Gershon, M.D.1
  • 20
    • 0034297908 scopus 로고    scopus 로고
    • Serotonin: A mediator of the brain-gut connection
    • D.Y. Kim, and M. Camilleri Serotonin: a mediator of the brain-gut connection Am J Gastroenterol 95 2000 2698 2709
    • (2000) Am J Gastroenterol , vol.95 , pp. 2698-2709
    • Kim, D.Y.1    Camilleri, M.2
  • 21
    • 0037450134 scopus 로고    scopus 로고
    • Toward a molecular architecture of personality
    • A. Reif, and K.P. Lesch Toward a molecular architecture of personality Behav Brain Res 139 2003 1 20
    • (2003) Behav Brain Res , vol.139 , pp. 1-20
    • Reif, A.1    Lesch, K.P.2
  • 22
    • 0034084644 scopus 로고    scopus 로고
    • Biogenic amine transporters: Regulation in flux
    • R.D. Blakely, and A.L. Bauman Biogenic amine transporters: regulation in flux Curr Opin Neurobiol 10 2000 328 336
    • (2000) Curr Opin Neurobiol , vol.10 , pp. 328-336
    • Blakely, R.D.1    Bauman, A.L.2
  • 23
    • 0032852641 scopus 로고    scopus 로고
    • Neurotransmitter transporters in the central nervous system
    • J. Masson, C. Sagn, and M. Hamon Neurotransmitter transporters in the central nervous system Pharmacol Rev 51 1999 439 464
    • (1999) Pharmacol Rev , vol.51 , pp. 439-464
    • Masson, J.1    Sagn, C.2    Hamon, M.3
  • 24
    • 0031681197 scopus 로고    scopus 로고
    • Guinea pig 5-HT transporter: Cloning, expression, distribution, and function in intestinal sensory reception
    • J.X. Chen, H. Pan, and T.P. Rothman Guinea pig 5-HT transporter: cloning, expression, distribution, and function in intestinal sensory reception Am J Physiol 275 1998 G433 G438
    • (1998) Am J Physiol , vol.275
    • Chen, J.X.1    Pan, H.2    Rothman, T.P.3
  • 25
    • 0029885161 scopus 로고    scopus 로고
    • Localization and function of a 5-HT transporter in crypt epithelia of the gastrointestinal tract
    • P.R. Wade, J. Chen, and B. Jaffe Localization and function of a 5-HT transporter in crypt epithelia of the gastrointestinal tract J Neurosci 16 1996 2352 2364
    • (1996) J Neurosci , vol.16 , pp. 2352-2364
    • Wade, P.R.1    Chen, J.2    Jaffe, B.3
  • 26
    • 0006463359 scopus 로고    scopus 로고
    • Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region
    • K.P. Lesch, D. Bengel, and A. Heils Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region Science 274 1996 1527 1531
    • (1996) Science , vol.274 , pp. 1527-1531
    • Lesch, K.P.1    Bengel, D.2    Heils, A.3
  • 27
    • 4644285181 scopus 로고    scopus 로고
    • Is there a SERT-ain association with IBS?
    • M. Camilleri Is there a SERT-ain association with IBS? Gut 53 2004 1396 1399
    • (2004) Gut , vol.53 , pp. 1396-1399
    • Camilleri, M.1
  • 28
    • 0034331195 scopus 로고    scopus 로고
    • Reduction in the density and expression, but not G-protein coupling, of serotonin receptors (5-HT1A) in 5-HT transporter knock-out mice: Gender and brain region differences
    • Q. Li, C. Wichems, and A. Heils Reduction in the density and expression, but not G-protein coupling, of serotonin receptors (5-HT1A) in 5-HT transporter knock-out mice: gender and brain region differences J Neurosci 20 2000 7888 7895
    • (2000) J Neurosci , vol.20 , pp. 7888-7895
    • Li, Q.1    Wichems, C.2    Heils, A.3
  • 29
    • 0037343950 scopus 로고    scopus 로고
    • Brain region-specific alterations of 5-HT2A and 5-HT2C receptors in serotonin transporter knockout mice
    • Q. Li, C.H. Wichems, and L. Ma Brain region-specific alterations of 5-HT2A and 5-HT2C receptors in serotonin transporter knockout mice J Neurochem 84 2003 1256 1265
    • (2003) J Neurochem , vol.84 , pp. 1256-1265
    • Li, Q.1    Wichems, C.H.2    Ma, L.3
  • 30
    • 0035882382 scopus 로고    scopus 로고
    • Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: Abnormal intestinal motility and the expression of cation transporters
    • J.J. Chen, Z. Li, and H. Pan Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: abnormal intestinal motility and the expression of cation transporters J Neurosci 21 2001 6348 6361
    • (2001) J Neurosci , vol.21 , pp. 6348-6361
    • Chen, J.J.1    Li, Z.2    Pan, H.3
  • 31
    • 0036890028 scopus 로고    scopus 로고
    • Expression and function of 5-HT3 receptors in the enteric neurons of mice lacking the serotonin transporter
    • M.T. Liu, S. Rayport, and Y. Jiang Expression and function of 5-HT3 receptors in the enteric neurons of mice lacking the serotonin transporter Am J Physiol 283 2002 G1398 G1411
    • (2002) Am J Physiol , vol.283
    • Liu, M.T.1    Rayport, S.2    Jiang, Y.3
  • 32
    • 0038339428 scopus 로고    scopus 로고
    • Serotonin availability is increased in mucosa of guinea pigs with TNBS-induced colitis
    • D.R. Linden, J.X. Chen, and M.D. Gershon Serotonin availability is increased in mucosa of guinea pigs with TNBS-induced colitis Am J Physiol 285 2003 G207 G216
    • (2003) Am J Physiol , vol.285
    • Linden, D.R.1    Chen, J.X.2    Gershon, M.D.3
  • 33
    • 2942525747 scopus 로고    scopus 로고
    • Molecular defects in mucosal serotonin content and decreased serotonin reuptake transporter in ulcerative colitis and irritable bowel syndrome
    • M.D. Coates, C.R. Mahoney, and D.R. Linden Molecular defects in mucosal serotonin content and decreased serotonin reuptake transporter in ulcerative colitis and irritable bowel syndrome Gastroenterology 126 2004 1657 1664
    • (2004) Gastroenterology , vol.126 , pp. 1657-1664
    • Coates, M.D.1    Mahoney, C.R.2    Linden, D.R.3
  • 34
    • 0033082533 scopus 로고    scopus 로고
    • Association between serotonin transporter gene polymorphism and anxiety-related traits
    • S. Katsuragi, H. Kunugi, and A. Sano Association between serotonin transporter gene polymorphism and anxiety-related traits Biol Psychiatry 45 1999 368 370
    • (1999) Biol Psychiatry , vol.45 , pp. 368-370
    • Katsuragi, S.1    Kunugi, H.2    Sano, A.3
  • 35
    • 0033605706 scopus 로고    scopus 로고
    • Study of the association between the serotonin transporter gene regulatory region polymorphism and personality traits in a Japanese population
    • C. Kumakiri, K. Kodama, and E. Shimizu Study of the association between the serotonin transporter gene regulatory region polymorphism and personality traits in a Japanese population Neurosci Lett 263 1999 205 207
    • (1999) Neurosci Lett , vol.263 , pp. 205-207
    • Kumakiri, C.1    Kodama, K.2    Shimizu, E.3
  • 36
    • 0006463359 scopus 로고    scopus 로고
    • Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region
    • K.P. Lesch, D. Bengel, and A. Heils Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region Science 274 1996 1527 1531
    • (1996) Science , vol.274 , pp. 1527-1531
    • Lesch, K.P.1    Bengel, D.2    Heils, A.3
  • 37
    • 0036177114 scopus 로고    scopus 로고
    • Drug efficacy at G protein-coupled receptors
    • T. Kenakin Drug efficacy at G protein-coupled receptors Annu Rev Pharmacol Toxicol 42 2002 349 379
    • (2002) Annu Rev Pharmacol Toxicol , vol.42 , pp. 349-379
    • Kenakin, T.1
  • 38
    • 9144239383 scopus 로고    scopus 로고
    • Platelet serotonin transporter in patients with diarrhea-predominant irritable bowel syndrome both before and after treatment with alosetron
    • M. Bellini, L. Rappelli, and C. Blandizzi Platelet serotonin transporter in patients with diarrhea-predominant irritable bowel syndrome both before and after treatment with alosetron Am J Gastroenterol 98 2003 2705 2711
    • (2003) Am J Gastroenterol , vol.98 , pp. 2705-2711
    • Bellini, M.1    Rappelli, L.2    Blandizzi, C.3
  • 39
    • 0037665412 scopus 로고    scopus 로고
    • Serotonin transporter and MAO-B levels in monoamine nuclei of the human brainstem are normal in major depression
    • V. Klimek, G. Roberson, and C.A. Stockmeier Serotonin transporter and MAO-B levels in monoamine nuclei of the human brainstem are normal in major depression J Psychiatr Res 37 2003 387 397
    • (2003) J Psychiatr Res , vol.37 , pp. 387-397
    • Klimek, V.1    Roberson, G.2    Stockmeier, C.A.3
  • 40
    • 85044698597 scopus 로고    scopus 로고
    • Decrease in the platelet level of 43 kDa immunoreactive fraction of serotonin transporting protein correlates with depressive symptoms in patients with somatoform disorders
    • A.R. Belous, S. Ramamoothy, and R.D. Blakely Decrease in the platelet level of 43 kDa immunoreactive fraction of serotonin transporting protein correlates with depressive symptoms in patients with somatoform disorders Vopr Med Khim 45 1999 256 262
    • (1999) Vopr Med Khim , vol.45 , pp. 256-262
    • Belous, A.R.1    Ramamoothy, S.2    Blakely, R.D.3
  • 41
    • 0035503323 scopus 로고    scopus 로고
    • Physiological genomics of antidepressant targets: Keeping the periphery in mind
    • R.D. Blakely Physiological genomics of antidepressant targets: keeping the periphery in mind J Neurosci 21 2001 8319 8323
    • (2001) J Neurosci , vol.21 , pp. 8319-8323
    • Blakely, R.D.1
  • 42
    • 0026534409 scopus 로고
    • Comorbidity of gastrointestinal complaints, depression, and anxiety in the Epidemiologic Catchment Area (ECA) study
    • E.A. Walker, W.J. Katon, and R.P. Jemelka Comorbidity of gastrointestinal complaints, depression, and anxiety in the Epidemiologic Catchment Area (ECA) study Am J Med 92 1992 26S 30S
    • (1992) Am J Med , vol.92
    • Walker, E.A.1    Katon, W.J.2    Jemelka, R.P.3
  • 43
    • 0031899668 scopus 로고    scopus 로고
    • The relationship between irritable bowel syndrome and psychiatric illness. A family study
    • C.L. Woodman, K. Breen, and R. Noyes Jr. The relationship between irritable bowel syndrome and psychiatric illness. A family study Psychosomatics 39 1998 45 54
    • (1998) Psychosomatics , vol.39 , pp. 45-54
    • Woodman, C.L.1    Breen, K.2    Noyes Jr., R.3
  • 44
    • 0036325415 scopus 로고    scopus 로고
    • Serotonin transporter polymorphism pharmacogenetics in diarrhea-predominant irritable bowel syndrome
    • M. Camilleri, E. Atanasova, and P.J. Carlson Serotonin transporter polymorphism pharmacogenetics in diarrhea-predominant irritable bowel syndrome Gastroenterology 123 2002 425 432
    • (2002) Gastroenterology , vol.123 , pp. 425-432
    • Camilleri, M.1    Atanasova, E.2    Carlson, P.J.3
  • 45
    • 0023628340 scopus 로고
    • Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor
    • B.K. Kobilka, H. Matsui, and T.S. Koblika Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor Science 238 1987 650 656
    • (1987) Science , vol.238 , pp. 650-656
    • Kobilka, B.K.1    Matsui, H.2    Koblika, T.S.3
  • 46
    • 0025279114 scopus 로고
    • Expansion of the alpha 2-adrenergic receptor family: Cloning and characterization of a human alpha 2-adrenergic receptor subtype, the gene for which is located on chromosome 2
    • J.W. Lomasney, W. Lorenz, and L.F. Allen Expansion of the alpha 2-adrenergic receptor family: cloning and characterization of a human alpha 2-adrenergic receptor subtype, the gene for which is located on chromosome 2 Proc Natl Acad Sci U S A 87 1990 5094 5098
    • (1990) Proc Natl Acad Sci U S a , vol.87 , pp. 5094-5098
    • Lomasney, J.W.1    Lorenz, W.2    Allen, L.F.3
  • 47
    • 1842283729 scopus 로고
    • Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype
    • J.W. Regan, T.S. Kobilka, and T.L. Yang-Feng Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype Proc Natl Acad Sci U S A 85 1988 6301 6305
    • (1988) Proc Natl Acad Sci U S a , vol.85 , pp. 6301-6305
    • Regan, J.W.1    Kobilka, T.S.2    Yang-Feng, T.L.3
  • 48
    • 0041506933 scopus 로고    scopus 로고
    • Pharmacology and physiology of human adrenergic receptor polymorphisms
    • K.M. Small, D.W. McGraw, and S.B. Liggett Pharmacology and physiology of human adrenergic receptor polymorphisms Annu Rev Pharmacol Toxicol 43 2003 381 411
    • (2003) Annu Rev Pharmacol Toxicol , vol.43 , pp. 381-411
    • Small, K.M.1    McGraw, D.W.2    Liggett, S.B.3
  • 49
    • 0042331424 scopus 로고    scopus 로고
    • Drug addiction
    • J. Cami, and M. Farre Drug addiction N Engl J Med 349 2003 975 986
    • (2003) N Engl J Med , vol.349 , pp. 975-986
    • Cami, J.1    Farre, M.2
  • 50
    • 0037442235 scopus 로고    scopus 로고
    • Genetic associations in large versus small studies: An empirical assessment
    • J.P. Ioannidis, T.A. Trikalinos, and E.E. Ntzani Genetic associations in large versus small studies: an empirical assessment Lancet 361 2003 567 571
    • (2003) Lancet , vol.361 , pp. 567-571
    • Ioannidis, J.P.1    Trikalinos, T.A.2    Ntzani, E.E.3
  • 51
    • 0037442092 scopus 로고    scopus 로고
    • Population stratification and spurious allelic association
    • L.R. Cardon, and L.J. Palmer Population stratification and spurious allelic association Lancet 361 2003 598 604
    • (2003) Lancet , vol.361 , pp. 598-604
    • Cardon, L.R.1    Palmer, L.J.2
  • 52
    • 0037426052 scopus 로고    scopus 로고
    • Problems of reporting genetic associations with complex outcomes
    • H.M. Colhoun, P.M. McKeigue, and G. Davey Smith Problems of reporting genetic associations with complex outcomes Lancet 361 2003 865 872
    • (2003) Lancet , vol.361 , pp. 865-872
    • Colhoun, H.M.1    McKeigue, P.M.2    Davey Smith, G.3
  • 53
    • 16844364043 scopus 로고    scopus 로고
    • Effect of CCK-1 antagonist, dexloxiglumide, in female patients with irritable bowel syndrome: A pharmacodynamic and pharmacogenomic study
    • F. Cremonini, M. Camilleri, and S. McKinzie Effect of CCK-1 antagonist, dexloxiglumide, in female patients with irritable bowel syndrome: a pharmacodynamic and pharmacogenomic study Am J Gastroenterol 100 2005 652 663
    • (2005) Am J Gastroenterol , vol.100 , pp. 652-663
    • Cremonini, F.1    Camilleri, M.2    McKinzie, S.3


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