Association between serotonin transporter gene polymorphism and anxiety- related traits

Biological Psychiatry

Volumn 45, Issue 3, 1999, Pages 368-370

  Katsuragi, Satomi ^a   Kunugi, Hiroshi ^b   Sano, Akira ^c   Tsutsumi, Takashi ^a   Isogawa, Koichi ^a   Nanko, Shinichiro ^b   Akiyoshi, Jotaro ^a  

^a OITA UNIVERSITY   (Japan)

^b TEIKYO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Anxiety; Harm avoidance; Personality; Polymorphism; Promoter; Serotonin; Transporter; Tridimensional personality questionnaire

Indexed keywords

SEROTONIN TRANSPORTER;

ADULT; ALLELE; ANXIETY; ANXIETY NEUROSIS; ARTICLE; AVOIDANCE BEHAVIOR; FEMALE; GENETIC POLYMORPHISM; HUMAN; MAJOR CLINICAL STUDY; MALE; PERSONALITY; PERSONALITY TEST; PRIORITY JOURNAL;

ADULT; ALLELES; ANALYSIS OF VARIANCE; ANXIETY; CARRIER PROTEINS; CHI-SQUARE DISTRIBUTION; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; JAPAN; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; NERVE TISSUE PROTEINS; NEUROTIC DISORDERS; PERSONALITY; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS;

EID: 0033082533     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3223(98)00090-0     Document Type: Article

References (11)

1. Aschauer H.N., Stompe T., Fureder T., et al. Normal personality traits related to neurotransmitter receptor genes. Psychiatr Genet. 6:1996;164.
2. Benjamin J., Creenberg B., Murphy D.L., et al. Mapping personality traits to genes Population and family association between the D4 dopamine receptor and measures of novelty seeking . Nat Genet. 12:1996;81-84.
3. Bouchard T.J. Genes and environment and personality. Science. 264:1994;1700-1701.
4. Cloninger C.R. A systematic method for clinical description and classification of personality variants. Arch Gen Psychiatry. 44:1987;573-588.
5. Ebstein R.P., Novick O., Umansky R., et al. D4DR exon III polymorphism associated with the personality trait of Novelty Seeking in normal human volunteers. Nat Genet. 12:1996;78-80.
6. Ebstein R.P., Gritsenko I., Nemanov L., et al. No association between the serotonin transporter gene regulatory region polymorphism and the tridimensional personality questionnaire (TPQ) temperament of harm avoidance. Mol Psychiatry. 2:1997;224-226.
7. Ebstein R.P., Segman R., Benjamin J. 5-HT2C (HTR2C) serotonin receptor gene polymorphism associated with the human personality trait of reward dependence Interaction with dopamine D4 receptor (D4DR) and dopamine D3 (D3DR) polymorphisms . Am J Med Genet. 74:1997;65-72.
8. Jonsson E., Nothen M.M., Custavsson J.P. DRD4 polymorphisms and personality traits in a Swedish sample of healthy volunteers. Psychiatr Genet. 6:1996;165.
9. Lesch K.P., Bengel D., Heils A., et al. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science. 274:1996;1527-1530.
10. McCartney K., Harris M.J., Bernieri F. Growing up and growing apart A developmental meta-analysis of twin studies . Psychol Bull. 107:1990;226-237.
11. Plomin R., Owen M.J., McCuffin P. The genetic basis of complex human behaviors. Science. 264:1994;1733-1739.