Synthesis, in vitro, and in vivo characterization of an integrin αvβ3-targeted molecular probe for optical imaging of tumor

Bioorganic and Medicinal Chemistry

Volumn 13, Issue 11, 2005, Pages 3763-3771

  Burnett, Christopher A ^a   Xie, Jianwu ^a   Quijano, Jade ^a   Shen, Zhimin ^b   Hunter, Finie ^a   Bur, Monica ^a   Li, King C P ^a   Danthi, S Narasimhan ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Imaging; Integrin v 3; Molecular probe; Tumor

Indexed keywords

2 (TERT BUTYLOXYCARBONYLAMINO)ETHYL 1 O CARBONYLIMIDAZOLE; 3 (TERT BUTYLOXYCARBONYLAMINO)NEOPENTYL 1 O CARBONYLIMIDAZOLE; 3 (TERT BUTYLOXYCARBONYLAMINO)PROPYL 1 O CARBONYLIMIDAZOLE; 4 (TERT BUTYLOXYCARBONYLAMINO)BUTYL 1 O CARBONYLIMIDAZOLE; 4 [2 (3,4,5,6 TETRAHYDROPYRIMIDIN 2 YLAMINO)ETHYLOXY]BENZOYL 2 [N (2 AMINOETHYL 1 CARBAMYL)]AMINOETHYLSULFONYLAMINO BETA ALANINE; 4 [2 (3,4,5,6 TETRAHYDROPYRIMIDIN 2 YLAMINO)ETHYLOXY]BENZOYL 2 [N (2 BUTYLOXYCARBONYLAMINOETHYL 1 CARBAMYL)]AMINOETHYLSULFONYLAMINO BETA ALANINE; 4 [2 (3,4,5,6 TETRAHYDROPYRIMIDIN 2 YLAMINO)ETHYLOXY]BENZOYL 2 [N (3 AMINONEOPENTA 1 CARBAMYL)]AMINOETHYLSULFONYLAMINO BETA ALANINE; 4 [2 (3,4,5,6 TETRAHYDROPYRIMIDIN 2 YLAMINO)ETHYLOXY]BENZOYL 2 [N (3 AMINONEOPENTA 1 CARBAMYL)]AMINOETHYLSULFONYLAMINO BETA ALANINE FLUORESCEIN THIOUREA; 4 [2 (3,4,5,6 TETRAHYDROPYRIMIDIN 2 YLAMINO)ETHYLOXY]BENZOYL 2 [N (3 AMINOPROPYL 1 CARBAMYL)]AMINOETHYLSULFONYLAMINO BETA ALANINE; 4 [2 (3,4,5,6 TETRAHYDROPYRIMIDIN 2 YLAMINO)ETHYLOXY]BENZOYL 2 [N (3 BUTYLOXYCARBONYLAMINONEOPENTA 1 CARBAMYL)] AMINOETHYLSULFONYLAMINO BETA ALANINE; 4 [2 (3,4,5,6 TETRAHYDROPYRIMIDIN 2 YLAMINO)ETHYLOXY]BENZOYL 2 [N (3 BUTYLOXYCARBONYLAMINOPROPYL 1 CARBAMYL)]AMINOETHYLSULFONYLAMINO BETA ALANINE; 4 [2 (3,4,5,6 TETRAHYDROPYRIMIDIN 2 YLAMINO)ETHYLOXY]BENZOYL 2 [N (4 AMINOBUTYL 1 CARBAMYL)]AMINOETHYLSULFONYLAMINO BETA ALANINE; 4 [2 (3,4,5,6 TETRAHYDROPYRIMIDIN 2 YLAMINO)ETHYLOXY]BENZOYL 2 [N (4 BUTYLOXYCARBONYLAMINOBUTYL 1 CARBAMYL)]AMINOETHYLSULFONYLAMINO BETA ALANINE; IMIDAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ADHESION; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; DRUG TARGETING; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HYDROPHOBICITY; IC 50; IMAGING SYSTEM; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR PROBE; NONHUMAN; RECEPTOR AFFINITY;

ANIMALIA;

EID: 18144380376     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.03.024     Document Type: Article

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