Targeting the expression of integrin receptors in tumors

Proceedings of SPIE - The International Society for Optical Engineering

Volumn 5329, Issue , 2004, Pages 222-228

  Bloch, S ^a   Liang, K ^a   Dorshow, R B ^a   Ye, Y ^a   Achilefu, S ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cell surface receptors; Integrin; Mouse; Optical imaging; Peptide; Tumor

Indexed keywords

CELL SURFACE RECEPTORS; INTEGRIN; OPTICAL IMAGING; PEPTIDE;

CHARGE COUPLED DEVICES; FLUORESCENCE; INFRARED RADIATION; LIGHT ABSORPTION; OPTICAL IMAGE STORAGE; PROBES; PROTEINS; TISSUE; TUMORS; ULTRAVIOLET RADIATION;

ONCOLOGY;

EID: 7644231265     PISSN: 0277786X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.533160     Document Type: Conference Paper

References (30)

1. J.S. Lewis, S. Achilefu, J.R. Barbow, R. Laforest, M.J. Welch. "Small animal imaging: current technology and perspectives for oncological imaging." Eu J Cancer 38, 2173-2188, 2002.
2. V. Ntziachristos, A.G. Yodh, M. Schnall, B. Chance. "Concurrent MRI and diffuse optical tomography of breast after indocyanine green enhancement." Proc Natl Acad Sci USA 97, 2767-2772, 2000.
3. S. Nioka, Y. Yung, M. Shnall, S. Zhao, S. Orel, C. Xie, B. Chance, L Solin. "Optical imaging of breast tumor by means of continuous waves. " Adv Exp Med Biol 411, 227-232, 1997.
4. E.M. Sevick-Muraca, G. Lopez, J.S. Reynolds, T.L. Troy, C.L. Hutchinson. "Fluorescence and absorption contrast mechanisms for biomedical optical imaging using frequency-domain techniques." Photochem Photobiol 66, 55-64, 1997.
5. C.A. Vogel, M.C. Galmiche, P. Westermann, L.Q. Sun, A. Pelegrin, S. Folli, A. Bischof Delaloye, D.O. Slosman, F. Buchegger. "Carcinoembryonic antigen expression, antibody localization and immunophotodetection of human colon cancer liver metastases in nude mice: a model for radioimmunotherapy." Int J Cancer 67, 294-302, 1996.
6. B. Ballou, G.W. Fisher, T.R. Hakala, D.L. Farkas. "Tumor detection and visualization using cyanine fluorochromelabeled antibodies. Biotechnology Prog 13, 649-658, 1997.
7. S. Folli, P. Westermann, D. Braichotte, A. Pelegrin, G. Wagnieres, H. van den Bergh, J.P. Mach. "Antibody-indocyanin conjugates for immunophotodetection of human squamous cell carcinoma in nude mice." Cancer Res 54, 2643-2649, 1994.
8. B. Ballou, G.W. Fisher, J.S. Deng, T.R. Hakala, M. Srivastava, D.L. Farkas. "Cyanine fluorochrome-labeled antibodies in vivo: assessment of tumor imaging using Cy3, Cy5, Cy5.5, and Cy7. Cancer Detect Prev 22, 251-257, 1998.
9. B. Ballou, G.W. Fisher, A.S. Waggoner, D.L. Farkas, J.M. Reiland, R. Jaffe, R.B. Mujumdar, S.R. Mujumdar, T.R. Hakala. "Tumor labeling in vivo using cyanine-conjugated monoclonal antibodies." Cancer Immunol Immunother 41, 257-263, 1995.
10. J.E. Bugaj, S.Achilefu, R.B.Dorshow. "Novel fluorescent contrast agents for optical imaging of in vivo tumors based on a receptor-targeted dye-peptide conjugate platform." J. Biomedical Optics 6, 122-133, 2001.
11. Ruoslahti, E. and Pierschbacher, M.D. New perspectives in cell adhesion: RGD and integrins. Science (Wash. DC), 238, 491-497, 1987.
12. E.F. Plow, T.A. Haas, L. Zhang, J Loftus, J.W. Smith. "Ligand binding to integrins." J. Biol. Chem., 275, 21785-21788, 2000.
13. S.A. Mousa. "αv Vitronectin Receptors in Vascular-Mediated Disorders." Medicinal Research Reviews, 23, 190-199, 2003.
14. D. Cheresh. "Integrins: Structure, function and biological properties." Ad Mol Cell Biol. 6, 225-252, 1993.
15. E.F. Plow, T.A. Haas, L. Zhang, J. Loftus, J.W. Smith. "Ligand binding to integrins." J Biol Chem, 275, 21785-21788, 2000.
16. B.P. Eliceiri, and D.A. Cheresh, D.A. "The role of αv integrins during angiogenesis: insights into potential mechanisms of action and clinical development." J Clin Invest, 103, 1227-1230, 1999.
17. P.C. Brooks, R.A.F. Clark, DA. Cheresh. "Requirement of vascular integrin αvβ3 for angiogenesis." Science (Wash.), 264, 569-571, 1994.
18. R.A. Swerlick, E.J. Brown, Y. Xu, K.H. Lee, S. Manos, T.J. Lawley. "Expression and modulation of vitronectin receptor on human dermal microvascular endothelial cells." J Invest Dermatol. 99, 715-722. 1993.
19. S. Liekens, E. De Clercq, J. Neyts, "Angiogenesis: regulators and clinical applications." Biochem Pharmacol. 61, 253-270, 2001.
20. P.C. Brooks, S. Stromblad, R. Klemke, D. Visscher, F.H. Sarkar, D.A. Cheresh. "Anti-integrin αvβ3 blocks human breast cancer growth, and angiogenesis in human skin." J Chin Invest, 96, 1815- 1822, 1995.
21. P.C. Brooks, A. M. Montgomery, M. Rosenfeld, R.A. Reisfeld, T. Hu, G. Klier, D.A. Cheresh. "Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels." Cell 79, 1157-1164, 1994.
22. R. Allman, P. Cowburn, P., M. Mason,. "In vitro and in vivo effects of a cyclic peptide with affinity for the αvβ3 integrin in human melanoma cells." Eur J Cancer 36, 410-422, 2000.
23. R. Haubner, H.J. Wester, F. Burkhart, R. Senekowitsch-Schmidtke, W. Weber, S.L. Goodman, H. Kessler, M. Schwaiger. "Glycosylated RGD-containing peptides: tracer for tumor targeting and angiogenesis imaging with improved biokinetics." J Nucl Med. 42, 326-336, 2001.
24. P.M. Van Hagen, W. A. Breeman, H.R. Bernard, M. Schaar, C.M. Mooij, A. Srinivasan, MA. Schmidt, E. P. Krenning, M. de Jong. "Evaluation of a radiolabeled cyclic DPTA-RGD analogue for tumor imaging and radionuclide therapy." Int J Cancer 90, 186-198, 2000.
25. G.B. Sivolapenko,D. Skarlos, D. Pectasides, E. Stathopoulou, A. Milonakis, G. Sirmalis, A. Stattle, N.S. Courtenay Luck, K. Konstantinides, A. A. Epenetos. "Imaging of metastatic melanoma utilizing a technetium-99m labeled RGD-containing synthetic peptide." Eur J Nucl Med 25, 1383-1389, 1998.
26. R. Haubner, H.J. Wester, U. Reuning, R. Senekowitsch Schmidtke, B. Diefenbach, H. Kessler, G. Stocklin, M. Schwaiger. "Radiolabeled αvβ3 integrin antagonists: a new class of tracers for tumor targeting." J Nucl Med. 40, 1061-1071, 1999.
27. 18F-labeled RGD-containing glycopeptide and positron emission tomography." Cancer Res. 61, 1781-1785, 2000.
28. M.L. Janssen, W.J. Oyen, I. Dijkgraaf, L.F. Massuger, C. Frielink, D.S. Edwards, M. Rajopadhye, H. Boonstra, F.H. Corstens, O.C. Boerman. "Tumor targeting with radiolabeled αvβ3 integrin binding peptides in a nude mouse model." Cancer Res. 62, 6146-6151, 2002.
29. S. Achilefu, R.B. Dorshow, J.E. Bugaj, R. Rajagopalan. "Novel receptor-targeted fluorescent contrast agents for in vivo tumor imaging." Invest Radial. 35, 479-485, 2000.
30. Achilefu, S., Jimenez, H.N., Dorshow, R.B., Bugaj, J.E., Webb, E.G., Wilhelm, R.R., Rajagopalan, R., Johler, J. and Erion, J.L. Synthesis, in vitro receptor binding, and in vivo evaluation of fluorescein and carbocyanine peptide-based optical contrast agents. J. Med. Chem. 45: 2003-2015.