Mechanistic model of cardiac energy metabolism predicts localization of glycolysis to cytosolic subdomain during ischemia

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 288, Issue 5 57-5, 2005, Pages

  Zhou, Lufang ^a,c   Salem, Jennifer E ^b,c   Saidel, Gerald M ^a,c   Stanley, William C ^b,c   Cabrera, Marco E ^a,b,c,d  

^a Case Western Reserve University   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

^d CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Computer simulation; Cytosol; Metabolic channeling; Mitochondria; Redox state

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; GLYCOGEN; LACTIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

ARTICLE; CELLULAR DISTRIBUTION; CORONARY ARTERY BLOOD FLOW; CYTOSOL; ENERGY METABOLISM; ENERGY TRANSFER; GLYCOGEN METABOLISM; GLYCOLYSIS; HEART MUSCLE BLOOD FLOW; HEART MUSCLE ISCHEMIA; HEART MUSCLE METABOLISM; MATHEMATICAL MODEL; MITOCHONDRION; OXIDATION; PRIORITY JOURNAL;

COMPUTER SIMULATION; CYTOSOL; ENERGY METABOLISM; GLYCOLYSIS; HEART; HUMANS; MITOCHONDRIA; MODELS, CARDIOVASCULAR; MYOCARDIAL ISCHEMIA; MYOCARDIUM; OXIDATION-REDUCTION;

EID: 18044377998     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.01030.2004     Document Type: Article

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