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Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 17, 2001, Pages 2279-2282

Design and synthesis of glycolic and mandelic acid derivatives as factor Xa inhibitors

(15) Su, Ting a Wu, Yanhong a Doughan, Brandon a Kane Maguire, Kim a Marlowe, Charles K a Kanter, James P a Woolfrey, John a Huang, Brian a Wong, Paul a Sinha, Uma a Park, Gary a Malinowski, John a Hollenbach, Stan a Scarborough, Robert M a Zhu, Bing Yan a

a MILLENNIUM PHARMACEUTICALS INC (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 10A INHIBITOR; GLYCOLIC ACID DERIVATIVE; MANDELIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG DESIGN; DRUG EFFECT; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; RABBIT; RAT; THROMBOGENESIS;

ACETANILIDES; AMIDINES; ANIMALS; BIOLOGICAL AVAILABILITY; BLOOD COAGULATION TESTS; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; FACTOR XA; INHIBITORY CONCENTRATION 50; INJECTIONS, INTRAVENOUS; MANDELIC ACIDS; PHENYLACETATES; PLASMIN; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; SERINE PROTEINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; VENOUS THROMBOSIS;

EID: 17944369775 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/S0960-894X(01)00447-4 Document Type: Article

Times cited : (13)

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