Unraveling innate immunity using large scale N-ethyl-N-nitrosourea mutagenesis

Tissue Antigens

Volumn 65, Issue 5, 2005, Pages 395-401

  Hoebe, Kasper ^a   Beutler, B ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

CD36; ENU mutagenesis; Forward genetics; Innate immunity; Trif

Indexed keywords

BETA INTERFERON; CD36 ANTIGEN; ETHYLNITROSOUREA; INTERFERON; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

CYTOKINE RELEASE; GENE FUNCTION; GENE IDENTIFICATION; GENE MAPPING; GENE SEQUENCE; GENETIC PROCEDURES; GENOME ANALYSIS; HUMAN; IMMUNE RESPONSE; INNATE IMMUNITY; MOLECULAR CLONING; MUTAGENESIS; NONHUMAN; PEDIGREE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; TECHNIQUE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; ANTIGENS, CD36; ANTIGENS, DIFFERENTIATION; ETHYLNITROSOUREA; GENE TARGETING; GENES, RECESSIVE; GENETIC TECHNIQUES; HUMANS; IMMUNITY, NATURAL; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; MODELS, IMMUNOLOGICAL; MUTAGENESIS; MUTAGENS; MYELOID DIFFERENTIATION FACTOR 88; PHENOTYPE; RECEPTORS, CELL SURFACE; RECEPTORS, IMMUNOLOGIC; RECEPTORS, INTERLEUKIN-1; TOLL-LIKE RECEPTORS;

EID: 17844408438     PISSN: 00012815     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-0039.2005.00369.x     Document Type: Review

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