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Volumn 374, Issue 2, 1997, Pages 193-199

The effect of the interval between dose applications on the observed specific-locus mutation rate in the mouse following fractionated treatments of spermatogonia with ethylnitrosourea

Author keywords

Ethylnitrosourea; Fractionated dose application; Fractionation interval; In vivo; Mouse; Specific locus mutation test; Spermatogonia; Threshold dose response

Indexed keywords

ETHYLNITROSOUREA;

EID: 0343247805     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(96)00229-1     Document Type: Article
Times cited : (19)

References (39)
  • 2
    • 0002103702 scopus 로고
    • Dose-effect relationships of germ-cell mutations in mice
    • Y. Tazima, S. Kondo and Y. Kuroda (Eds.), Kokusai-bunken, Tokyo
    • Ehling, U.H. and A. Neuhäuser-Klaus (1984) Dose-effect relationships of germ-cell mutations in mice, in: Y. Tazima, S. Kondo and Y. Kuroda (Eds.), Problems of Threshold in Chemical Mutagenesis, Kokusai-bunken, Tokyo, pp. 12-25.
    • (1984) Problems of Threshold in Chemical Mutagenesis , pp. 12-25
    • Ehling, U.H.1    Neuhäuser-Klaus, A.2
  • 3
    • 0025338542 scopus 로고
    • A dose-response analysis of ethylnitrosourea-induced recessive specific-locus mutations in treated spermatogonia of the mouse
    • Favor, J., M. Sund, A. Neuhäuser-Klaus and U.H. Ehling (1990) A dose-response analysis of ethylnitrosourea-induced recessive specific-locus mutations in treated spermatogonia of the mouse, Mutation Res., 231, 47-54.
    • (1990) Mutation Res. , vol.231 , pp. 47-54
    • Favor, J.1    Sund, M.2    Neuhäuser-Klaus, A.3    Ehling, U.H.4
  • 5
    • 0023845940 scopus 로고
    • The effect of dose fractionation on the frequency of ethylnitrosourea-induced dominant cataract and recessive specific locus mutations in germ cells of the mouse
    • Favor, J., A. Neuhäuser-Klaus and U.H. Ehling (1988) The effect of dose fractionation on the frequency of ethylnitrosourea-induced dominant cataract and recessive specific locus mutations in germ cells of the mouse, Mutation Res., 198, 269-275.
    • (1988) Mutation Res. , vol.198 , pp. 269-275
    • Favor, J.1    Neuhäuser-Klaus, A.2    Ehling, U.H.3
  • 6
    • 0022369586 scopus 로고
    • Dose-repetition increases the mutagenic effectiveness of N-ethyl-N-nitrosourea in mouse spermatogonia
    • Hitotsumachi, S., D.A. Carpenter and W.L. Russell (1985) Dose-repetition increases the mutagenic effectiveness of N-ethyl-N-nitrosourea in mouse spermatogonia, Proc. Natl. Acad. Sci. USA, 82, 6619-6621.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 6619-6621
    • Hitotsumachi, S.1    Carpenter, D.A.2    Russell, W.L.3
  • 7
    • 0020265113 scopus 로고
    • Effect of dose fractionation on the ethylnitrosourea induction of specific-locus mutations in mouse spermatogonia
    • Russell, W.L., P.R. Hunsicker, D.A. Carpenter, C.V. Cornett and G.M. Guinn (1982) Effect of dose fractionation on the ethylnitrosourea induction of specific-locus mutations in mouse spermatogonia, Proc. Natl. Acad. Sci. USA, 79, 3592-3593.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 3592-3593
    • Russell, W.L.1    Hunsicker, P.R.2    Carpenter, D.A.3    Cornett, C.V.4    Guinn, G.M.5
  • 8
    • 0023766555 scopus 로고
    • Induction of specific-locus mutations in female mice by 1-ethyl-1-nitrosourea and procarbazine
    • Ehling, U.H. and A. Neuhäuser-Klaus (1988) Induction of specific-locus mutations in female mice by 1-ethyl-1-nitrosourea and procarbazine, Mutation Res., 202, 139-146.
    • (1988) Mutation Res. , vol.202 , pp. 139-146
    • Ehling, U.H.1    Neuhäuser-Klaus, A.2
  • 9
  • 10
    • 0024207906 scopus 로고
    • High frequency of mosaic mutations produced by N-ethyl-N-nitrosourea exposure of mouse zygotes
    • Russell, L.B., J.W. Bangham, K.F. Stelzner and P.R. Hunsicker (1988) High frequency of mosaic mutations produced by N-ethyl-N-nitrosourea exposure of mouse zygotes, Proc. Natl. Acad. Sci. USA, 85, 9167-9170.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 9167-9170
    • Russell, L.B.1    Bangham, J.W.2    Stelzner, K.F.3    Hunsicker, P.R.4
  • 11
    • 0025734153 scopus 로고
    • The induction of forward and reverse specific-locus mutations and dominant cataract mutations in spermatogonia of treated strain DBA/2 mice by ethylnitrosourea
    • Favor, J., A. Neuhäuser-Klaus and U.H. Ehling (1991) The induction of forward and reverse specific-locus mutations and dominant cataract mutations in spermatogonia of treated strain DBA/2 mice by ethylnitrosourea, Mutation Res., 249, 293-300.
    • (1991) Mutation Res. , vol.249 , pp. 293-300
    • Favor, J.1    Neuhäuser-Klaus, A.2    Ehling, U.H.3
  • 12
    • 0001286896 scopus 로고
    • Activity measurements of erythrocyte enzymes in mice. Detection of a new class of gene mutations
    • Charles, D.J. and W. Pretsch (1982) Activity measurements of erythrocyte enzymes in mice. Detection of a new class of gene mutations, Mutation Res., 97, 177-178.
    • (1982) Mutation Res. , vol.97 , pp. 177-178
    • Charles, D.J.1    Pretsch, W.2
  • 13
    • 0023141442 scopus 로고
    • Linear dose-response relationship of erythrocyte enzyme-activity mutations in offspring of ethylnitrosourea-treated mice
    • Charles, D.J. and W. Pretsch (1987) Linear dose-response relationship of erythrocyte enzyme-activity mutations in offspring of ethylnitrosourea-treated mice, Mutation Res., 176, 81-91.
    • (1987) Mutation Res. , vol.176 , pp. 81-91
    • Charles, D.J.1    Pretsch, W.2
  • 14
    • 0020042688 scopus 로고
    • Dominant cataract and specific-locus mutations in mice induced by radiation or ethylnitrosourea
    • Ehling, U.H., J. Favor, J. Kratochvilova and A. Neuhäuser-Klaus (1982) Dominant cataract and specific-locus mutations in mice induced by radiation or ethylnitrosourea, Mutation Res., 92, 181-192.
    • (1982) Mutation Res. , vol.92 , pp. 181-192
    • Ehling, U.H.1    Favor, J.2    Kratochvilova, J.3    Neuhäuser-Klaus, A.4
  • 16
    • 0020554783 scopus 로고
    • A comparison of the dominant cataract and recessive specific-locus mutation rates induced by treatment of male mice with ethylnitrosourea
    • Favor, J. (1983) A comparison of the dominant cataract and recessive specific-locus mutation rates induced by treatment of male mice with ethylnitrosourea, Mutation Res., 110, 367-382.
    • (1983) Mutation Res. , vol.110 , pp. 367-382
    • Favor, J.1
  • 17
    • 0022487304 scopus 로고
    • A comparison of the mutation rates to dominant and recessive alleles in germ-cells of the mouse
    • Favor, J. (1986) A comparison of the mutation rates to dominant and recessive alleles in germ-cells of the mouse, Prog. Clin. Biol. Res., 209B, 519-526.
    • (1986) Prog. Clin. Biol. Res. , vol.209 B , pp. 519-526
    • Favor, J.1
  • 18
    • 0022515192 scopus 로고
    • The frequency of dominant cataract and recessive specific-locus mutations in mice derived from 80 or 160 mg ethylnitrosourea per kg body weight treated spermatogonia
    • Favor, J. (1986) The frequency of dominant cataract and recessive specific-locus mutations in mice derived from 80 or 160 mg ethylnitrosourea per kg body weight treated spermatogonia, Mutation Res., 162, 69-80.
    • (1986) Mutation Res. , vol.162 , pp. 69-80
    • Favor, J.1
  • 19
    • 0343597187 scopus 로고
    • Electrophoretically detected germinal mutations induced in the mouse by ethylnitrosourea
    • Johnson, P.M. and S.E. Lewis (1981) Electrophoretically detected germinal mutations induced in the mouse by ethylnitrosourea, Proc. Natl. Acad. Sci. USA, 78, 3138-3141.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 3138-3141
    • Johnson, P.M.1    Lewis, S.E.2
  • 20
    • 0022503411 scopus 로고
    • The detection of gene mutations by electrophoresis, and their analysis
    • Peters, J., S.T. Ball and S.J. Andrews (1986) The detection of gene mutations by electrophoresis, and their analysis, Prog. Clin. Biol. Res., 209B, 367-374.
    • (1986) Prog. Clin. Biol. Res. , vol.209 B , pp. 367-374
    • Peters, J.1    Ball, S.T.2    Andrews, S.J.3
  • 21
    • 0022595526 scopus 로고
    • Chemical dosimetry of ethyl nitrosourea in the mouse testis
    • Sega, G.A., C.R. Rohrer, H.R. Harvey and A.E. Jetton (1986) Chemical dosimetry of ethyl nitrosourea in the mouse testis, Mutation Res., 159, 65-74.
    • (1986) Mutation Res. , vol.159 , pp. 65-74
    • Sega, G.A.1    Rohrer, C.R.2    Harvey, H.R.3    Jetton, A.E.4
  • 22
    • 0025369725 scopus 로고
    • DNA adduct formation in mouse testis by ethylating agents. a comparison with germ cell mutagenesis
    • Van Zeeland, A.A., A. de Groot and A. Neuhäuser-Klaus (1990) DNA adduct formation in mouse testis by ethylating agents. A comparison with germ cell mutagenesis. Mutation Res., 231, 55-62.
    • (1990) Mutation Res. , vol.231 , pp. 55-62
    • Van Zeeland, A.A.1    De Groot, A.2    Neuhäuser-Klaus, A.3
  • 23
    • 0002927273 scopus 로고
    • Recessive and dominant mutations in mice
    • E.H.Y. Chu and W.M. Generoso (Eds.), Plenum Press, New York
    • Ehling, U.H. and J. Favor (1984) Recessive and dominant mutations in mice, in: E.H.Y. Chu and W.M. Generoso (Eds.), Mutation, Cancer and Malformation, Plenum Press, New York, pp. 389-428.
    • (1984) Mutation, Cancer and Malformation , pp. 389-428
    • Ehling, U.H.1    Favor, J.2
  • 24
    • 0000882753 scopus 로고
    • Mutation induction in mice
    • J.T. Lett, H. Adler and M. Zeile (Eds.), Academic Press, New York-London
    • Searle, A.G. (1974) Mutation induction in mice, in: J.T. Lett, H. Adler and M. Zeile (Eds.), Advances in Radiation Biology, Vol. 4, Academic Press, New York-London, pp. 131-209.
    • (1974) Advances in Radiation Biology , vol.4 , pp. 131-209
    • Searle, A.G.1
  • 25
    • 0003475935 scopus 로고
    • Toward an understanding of the mechanisms of mutation induction by ethylnitrosourea in germ cells of the mouse
    • J.W. Allen, B.A. Bridges, M.F. Lyon, M.J. Moses and L.B. Russell (Eds.), Cold Spring Harbor Press, Cold Spring Harbor, NY
    • Favor, J. (1990) Toward an understanding of the mechanisms of mutation induction by ethylnitrosourea in germ cells of the mouse, in: J.W. Allen, B.A. Bridges, M.F. Lyon, M.J. Moses and L.B. Russell (Eds.), Banbury Report 34: Biology of Mammalian Germ Cell Mutagenesis, Cold Spring Harbor Press, Cold Spring Harbor, NY, pp. 221-235.
    • (1990) Banbury Report 34: Biology of Mammalian Germ Cell Mutagenesis , vol.34 , pp. 221-235
    • Favor, J.1
  • 26
    • 0015025552 scopus 로고
    • Spermatogonial stem cell renewal in the mouse
    • Oakberg, E.F. (1971) Spermatogonial stem cell renewal in the mouse, Anat. Rec., 169, 119-127.
    • (1971) Anat. Rec. , vol.169 , pp. 119-127
    • Oakberg, E.F.1
  • 27
    • 0026355151 scopus 로고
    • The molecular characterization of an A:T to G:C transition in the Hbb-b1 gene of the murine homologue of hemoglobin Rainier
    • Jones, J. and J. Peters (1991) The molecular characterization of an A:T to G:C transition in the Hbb-b1 gene of the murine homologue of hemoglobin Rainier, Biochem. Genet., 29, 617-626.
    • (1991) Biochem. Genet. , vol.29 , pp. 617-626
    • Jones, J.1    Peters, J.2
  • 29
    • 0028600585 scopus 로고
    • The mouse segmentation gene kr encodes a novel basic domain-leucine zipper transcription factor
    • Cordes, S.P. and G.S. Barsh (1994) The mouse segmentation gene kr encodes a novel basic domain-leucine zipper transcription factor, Cell, 79, 1025-1034.
    • (1994) Cell , vol.79 , pp. 1025-1034
    • Cordes, S.P.1    Barsh, G.S.2
  • 31
    • 0025043858 scopus 로고
    • The molecular basis of brown, an old mouse mutation, and of an induced revenant to wild type
    • Zdarsky, E., J. Favor and I.J. Jackson (1990) The molecular basis of brown, an old mouse mutation, and of an induced revenant to wild type, Genetics, 126, 443-449.
    • (1990) Genetics , vol.126 , pp. 443-449
    • Zdarsky, E.1    Favor, J.2    Jackson, I.J.3
  • 32
    • 0029449972 scopus 로고
    • Sequence characterization of ENU-induced mutants of glucose phosphate isomerase in mouse
    • Pearce, S.R., J. Peters, S. Ball, M.J. Morgan, J.I.H. Walker and P. Faik (1995) Sequence characterization of ENU-induced mutants of glucose phosphate isomerase in mouse, Mammalian Genome, 6, 858-861.
    • (1995) Mammalian Genome , vol.6 , pp. 858-861
    • Pearce, S.R.1    Peters, J.2    Ball, S.3    Morgan, M.J.4    Walker, J.I.H.5    Faik, P.6
  • 35
    • 0028954123 scopus 로고
    • Molecular analysis of four ENU induced triosephosphate isomerase null mutants in Mus musculus
    • Zingg, B.C., W. Pretsch and H.W. Mohrenweiser (1995) Molecular analysis of four ENU induced triosephosphate isomerase null mutants in Mus musculus, Mutation Res., 328, 163-173.
    • (1995) Mutation Res. , vol.328 , pp. 163-173
    • Zingg, B.C.1    Pretsch, W.2    Mohrenweiser, H.W.3
  • 37
    • 0027406541 scopus 로고
    • Mutagenic processing of ethylation damage in mammalian cells: The use of methoxyamine to study the AP site-induced mutagenesis
    • Fortini, P., A. Calcagnile, H. Vrieling, A.A. van Zeeland, M. Bignami and E. Dogliotti (1993) Mutagenic processing of ethylation damage in mammalian cells: the use of methoxyamine to study the AP site-induced mutagenesis. Cancer Res., 53, 1149-1155.
    • (1993) Cancer Res. , vol.53 , pp. 1149-1155
    • Fortini, P.1    Calcagnile, A.2    Vrieling, H.3    Van Zeeland, A.A.4    Bignami, M.5    Dogliotti, E.6
  • 38
    • 0028169610 scopus 로고
    • AT base pairs are the main target for mutations at the hprt locus of the rat skin fibroblasts exposed in vitro to the monofunctional alkylating agent N-ethyl-N-nitrosourea
    • Jansen, J.G., C.M.M. Van Teijlingen, G.R. Mohn, A.A. Van Zeeland and H. Vrieling (1994) AT base pairs are the main target for mutations at the hprt locus of the rat skin fibroblasts exposed in vitro to the monofunctional alkylating agent N-ethyl-N-nitrosourea, Mutagenesis, 9, 417-421.
    • (1994) Mutagenesis , vol.9 , pp. 417-421
    • Jansen, J.G.1    Van Teijlingen, C.M.M.2    Mohn, G.R.3    Van Zeeland, A.A.4    Vrieling, H.5
  • 39
    • 0020608081 scopus 로고
    • The effect of ethyl-, methyl- And hydroxyethyl-nitrosourea on the mouse testis
    • Oakberg, E.F. and C.D. Crosthwait (1983) The effect of ethyl-, methyl- and hydroxyethyl-nitrosourea on the mouse testis, Mutation Res., 108, 337-344.
    • (1983) Mutation Res. , vol.108 , pp. 337-344
    • Oakberg, E.F.1    Crosthwait, C.D.2


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