Deficiency of the macrophage migration inhibitory factor gene has no significant effect on endotoxaemia

Immunology

Volumn 100, Issue 1, 2000, Pages 84-90

  Honma, N ^a,b   Koseki, H ^b   Akasaka, T ^b   Nakayama, T ^b   Taniguchi, M ^b   Serizawa, I ^a   Akahori, H ^a   Osawa, M ^a   Mikayama, Toshifumi ^a,c  

^a KIRIN BREWERY CO LTD   (Japan)

^b CHIBA UNIVERSITY   (Japan)

^c Gemini Science   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; GLUCOCORTICOID; LIPOPOLYSACCHARIDE; MACROPHAGE MIGRATION INHIBITION FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DOSE RESPONSE; EMBRYO; ENDOTOXEMIA; GENE DISRUPTION; IMMUNE RESPONSE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; SEPTIC SHOCK;

ANIMALS; ANTI-INFLAMMATORY AGENTS; DEXAMETHASONE; ENDOTOXEMIA; FERTILITY; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MACROPHAGES, PERITONEAL; MICE; MICE, KNOCKOUT; SHOCK, SEPTIC; SURVIVAL RATE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0242445578     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.2000.00011.x     Document Type: Article

References (44)

1. 1. BLOOM B.R. & BENNETT B. (1966) Mechanism of a reaction in vitro associated with delayed-type hypersensitivity. Science 153, 80.
2. 2. DAVID J.R. (1966) Delayed hypersensitivity in vitro: its mediation by cell-free substances formed by lymphoid cell-antigen interaction. Proc Natl Acad Sci USA 56, 72.
3. 3. DAVID J.R. & DAVID R.A. (1972) Cellular hypersensitivity and immunity. Inhibition of macrophage migration and the lymphocyte mediators. Prog Allergy 16, 300.
4. 4. ROCKELIN R.E., RSEN F.S. & DAVID J.R. (1970) In vitro lymphocyte response of patients with immunologic deficiency diseases. Correlation of production of macrophage migration inhibitory factor with delayed hypersensitivity. N Engl J Med 282, 1340.
5. 5. WEISER W.Y., TEMPLE P.A., WITEK-GIANNOTTI J.S., REMOLD H.G., CLARK S.C. & DAVID J.R. (1989) Molecular cloning of a cDNA encoding a human macrophage migration inhibitory factor. Proc Natl Acad Sci USA 86, 7522.
6. 6. BERNHAGEN J., MITCHELL R.A., CALANDRA T., VOELTER W., CERAMI A. & BUCALA R. (1994) Purification, bioactivity, and secondary structure analysis of mouse and human macrophage migration inhibitory factor (MIF). Biochemistry 33, 14144.
7. 7. BERNHAGEN J., CALANDRA T., MITCHELL R.A. et al. (1993) MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia. Nature 365, 756.
8. 8. BRNHAGEN J., CALANDRA T., CERAMI A. & BUCALA R. (1994) Macrophage migration inhibitory factor is a neuroendocrine mediator of endotoxaemia. Trends Microbiol 2, 198.
9. 9. BRNHAGEN J., CALANDRA T. & BUCALA R. (1994) The emerging role of MIF in septic shock and infection. Biotherapy 8, 123.
10. 10. CALANDRA T., BERNHAGEN J., MITCHELL R.A. & BUCALA R. (1994) The macrophage is an important and previously unrecognized source of macrophage migration inhibitory factor. J Exp Med 179, 1895.
11. 11. TRACEY K.J., FONG Y., HESSE D.G. et al. (1987) Anti-cachectin/ TNF monoclonal antibodies prevent septic shock during lethal bacteraemia. Nature 330, 662.
12. 12. MOHLER K.M., TORRANCE D.S., SMITH C.A. et al. (1993) Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxaemia and function simultaneously as both TNF carriers and TNF antagonists. J Immunol 151, 1548.
13. 13. CALANDRA T., BERNHAGEN J., METZ C.N. et al. (1995) MIF as a glucocorticoid-induced modulator of cytokine production. Nature 377, 68.
14. 14. ROSENGREN E., BUCALA R., AMAN P. et al. (1996) The immunoregulatory mediator macrophage migration inhibitory factor (MIF) catalyzes a tautomerization reaction. Mol Med 2, 143.
15. 15. KLFFMANN R., KAPURNIOTU A., FRANK R.W. et al. (1998) Disulfide analysis reveals a role for macrophage migration inhibitory factor (MIF) as thiol-protein oxidoreductase. J Mol Biol 280, 85.
16. 16. BOZZA M., KOLALOWSKI L.F. Jr, JENKINS N.A. et al. (1995) Structural characterization and chromosomal location of the mouse macrophage migration inhibitory factor gene and pseudogenes. Genomics 27, 412.
17. 17. MITCHELL R., BACHER M., BERNHAGEN J., PUSHKARSKAYA T., SFLDIN M.F. & BUCALA R. (1995) Cloning and characterization of the gene for mouse macrophage migration inhibitory factor (MIF). J Immunol 154, 3863.
18. 18. HONMA N., MATSUDA Y., ISHII Y. et al. (1996) Cloning and mapping of the mouse glycosylation-inhibiting factor gene and four related genes. Mammal Genome 7, 59.
19. 19. WURST W. & JOYNER A.L. (1993) Production of targeted embryonic stem cell clones. In: Gene Targeting: a Practical Approach (ed. A.L. JOYNER), p. 33. IRL Press, Oxford.
20. 20. NAGY A., ROSSANT J., NAGY R., ABRAMOW-NEWERLY W. & RODER J.C. (1993) Derivation of completely cell culture-derived mice from early passage embryonic stem cells. Proc Natl Acad Sci USA 90, 8424.
21. 21. STOSCHECK C.M. (1990) Quantitation of protein. In: Guide to Protein Purification (ed. M.P. DEUTSCHER), p. 55. Academic Press, New York.
22. 22. MIKAYAMA T., NAKANO T., GOMI H. et al. (1993) Molecular cloning and functional expression of a cDNA encoding glycosylation-inhibiting factor. Proc Natl Acad Sci USA 90, 10056.
23. 23. GALAT A., RIVIÉRE S. & BOVET F. (1993) Purification of macrophage migration inhibitory factor (MIF) from bovine brain cytosol. FEBS Lett 319, 233.
24. 24. BEUTLER B., MILSARK I.W. & CERAMI A.C. (1985) Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin. Science 229, 869.
25. 25. DOHERTY G.M., LANGE J.R., LANGSTEIN H.N., ALEXANDER H.R., BURESH C.M. & NORTON J.A. (1992) Evidence for IFN-γ as a mediator of the lethality of endotoxin and tumor necrosis factor-α. J Immunol 149, 1666.
26. 26. AMIOT F., FITTING C., TRACEY K.J., CAVAILLON J.M. & DAUTRY F. (1997) Lipopolysaccharide-induced cytokine cascade and lethality in LT alpha/TNF alpha-deficient mice. Mol Med 3, 864.
27. 27. GIFFORD G.E. & LOHMANN-MATTHES M.L. (1986) Requirement for the continual presence of lipopolysaccharide for production of tumor necrosis factor by thioglycollate-induced peritoneal murine macrophages. Int J Cancer 38, 135.
28. 28. LANAHAN A., WILLIAMS J.B., SANDERS L.K. & NATHANS D. (1992) Growth factor-induced delayed early response genes. Mol Cell Biol 12, 3919.
29. 29. FONG Y., TRACEY K.J., MOLDAWER L.L. et al. (1989) Antibodies to cachectin/tumor necrosis factor reduce interleukin 1 beta and interleukin 6 appearance during lethal bacteremia. J Exp Med 170, 1627.
30. 30. MARTICH G.D., DANNER R.L., CESKA M. & SUFFREDINI A.F. (1991) Detection of interleukin 8 and tumor necrosis factor in normal humans after intravenous endotoxin: the effect of antiinflammatory agents. J Exp Med 173, 1021.
31. 31. NEEDLEMAN P., TURK J., JAKSCHIK B.A., MORRISON A.R. & LEFKOWITH J.B. (1986) Arachidonic acid metabolism. Annu Rev Biochem 55, 69.
32. 32. STUEHR D.J., GROSS S.S., SAKUMA I., LEVI R. & NATHAN C.F. (1989) Activated murine macrophages secrete a metabolite of arginine with the bioactivity of endothelium-derived relaxing factor and the chemical reactivity of nitric oxide. J Exp Med 169, 1011.
33. 33. JUTTNER S., BERNHAGEN J., METZ C.N., ROLLINGHOFF M., BUCALA R. & GESSNER A. (1998) Migration inhibitory factor induces killing of Leishmania major by macrophages: dependence on reactive nitrogen intermediates and endogenous TNF-alpha. J Immunol 161, 2383.
34. 34. FREI K., EUGSTER H.P., BOPST M., CONSTANTINESCU C.S., LAVI E. & FONTANA A. (1997) Tumor necrosis factor alpha and lymphotoxin alpha are not required for induction of acute experimental autoimmune encephalomyelitis. J Exp Med 185, 2177.
35. 35. RUDDLE N.H., BERGMAN C.M., MCGRATH K.M. et al. (1990) An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis. J Exp Med 172, 1193.
36. 36. BOZZA M., SATOSKAR A.R., LIN G. et al. (1999) Targeted disruption of migration inhibitory factor gene reveals its critical role in sepsis. J Exp Med 189, 341.
37. 37. FREUDENBERG M.A. & GALANOS C. (1988) Induction of tolerance to lipopolysaccharide (LPS)-D-galactosamine lethality by pretreati ment with LPS is mediated by macrophage. Infect Immun 56, 1352.
38. 38. BUNDSCHUH D.S., BARSIG J., HARTUNG T. et al. (1997) Granulocyte-macrophage colony-stimulating factor and IFN-gamma restore the systemic TNF-alpha response to endotoxin in lipopolysaccharide-desensitized mice. J Immunol 158, 2862.
39. 39. RANDOW F., SYRBE U., MEISEL C. et al. (1995) Mechanism of endotoxin desensitization: involvement of interleukin 10 and transforming growth factor beta. J Exp Med 181, 1887.
40. 40. EVANS G.F. & ZUCKERMAN S.H. (1991) Glucocorticoid-dependent and -independent mechanisms involved in lipopolysaccharide tolerance. Eur J Immunol 21, 1973.
41. 41. WEIGLE W.O., GAHRING L.C., ROMBALL C.G. & GOODMAN M.G. (1989) The effect of lipopolysaccharide desensitization on the regulation of in vivo induction of immunologic tolerance and antibody production and in vitro release of IL-1. J Immunol 142, 1107.
42. 42. BALKHY H.H. & HEINZEL F.P. (1999) Endotoxin fails to induce IFN-γ in endotoxin-tolerant mice: deficiencies in both IL-12 heterodimer production and IL-12 responsiveness. J Immunol 162, 3633.
43. 43. APTE R.S., SINHA D., MAYHEW E., WISTOW G.J. & NIEDERKORN J.Y. (1998) Role of macrophage migration inhibitory factor in inhibiting NK cell activity and preserving immune privilege. J Immunol 160, 5693.
44. 44. SUGIE K., NAKANO T., TOMURA T., TAKAKURA K., MIKAYAMA T. & ISHIZAKA K. (1997) High-affinity binding of bioactive glycosylation-inhibiting factor to antigen-primed T cells and natural killer cells. Proc Natl Acad Sci USA 94, 5278.