-
1
-
-
0033797241
-
A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance
-
Baier LJ, Permana PA, Yang X, Pratley RE, Hanson RL, Shen GQ, Mott D, Knowler WC, Cox NJ, Horikawa Y, Oda N, Bell GI & Bogardus C 2000 A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance. Journal of Clinical Investigation 106 R69-R73.
-
(2000)
Journal of Clinical Investigation
, vol.106
-
-
Baier, L.J.1
Permana, P.A.2
Yang, X.3
Pratley, R.E.4
Hanson, R.L.5
Shen, G.Q.6
Mott, D.7
Knowler, W.C.8
Cox, N.J.9
Horikawa, Y.10
Oda, N.11
Bell, G.I.12
Bogardus, C.13
-
3
-
-
0037423268
-
Opposite effects of background genotype on muscle and liver insulin sensitivity of lipoatrophic mice. Role of triglyceride clearance
-
Colombo C, Haluzik M, Cutson JJ, Dietz KR, Marcus-Samuels B, Vinson C, Gavrilova O & Reitman ML 2003 Opposite effects of background genotype on muscle and liver insulin sensitivity of lipoatrophic mice. Role of triglyceride clearance. Journal of Biological Chemistry 278 3992-3999.
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 3992-3999
-
-
Colombo, C.1
Haluzik, M.2
Cutson, J.J.3
Dietz, K.R.4
Marcus-Samuels, B.5
Vinson, C.6
Gavrilova, O.7
Reitman, M.L.8
-
5
-
-
0036796875
-
Oxidative stress and stress-activated signaling pathways: A unifying hypothesis of type 2 diabetes
-
Evans JL, Goldfine ID, Maddux BA & Grodsky GM 2002 Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocrine Reviews 23 599-622.
-
(2002)
Endocrine Reviews
, vol.23
, pp. 599-622
-
-
Evans, J.L.1
Goldfine, I.D.2
Maddux, B.A.3
Grodsky, G.M.4
-
6
-
-
0036078427
-
Adipose tissue-specific increase in angiotensinogen expression and secretion in the obese (fa/fa) Zucker rat
-
Hainault I, Nebout G, Turban S, Ardouin B, Ferre P & Quignard-Boulange A 2002 Adipose tissue-specific increase in angiotensinogen expression and secretion in the obese (fa/fa) Zucker rat. American Journal of Physiology. Endocrinology and Metabolism 282 E59-E66.
-
(2002)
American Journal of Physiology. Endocrinology and Metabolism
, vol.282
-
-
Hainault, I.1
Nebout, G.2
Turban, S.3
Ardouin, B.4
Ferre, P.5
Quignard-Boulange, A.6
-
7
-
-
0033590160
-
Identification and characterization of SorCS, a third member of a novel receptor family
-
Hermey G, Riedel IB, Hampe W, Schaller HG & Hermans-Borgmeyer I 1999 Identification and characterization of SorCS, a third member of a novel receptor family. Biochemical and Biophysical Research Communications 266 347-351.
-
(1999)
Biochemical and Biophysical Research Communications
, vol.266
, pp. 347-351
-
-
Hermey, G.1
Riedel, I.B.2
Hampe, W.3
Schaller, H.G.4
Hermans-Borgmeyer, I.5
-
8
-
-
0037153158
-
A central role for JNK in obesity and insulin resistance
-
Hirosumi J, Tuncman G, Chang L, Gorgun CZ, Uysal KT, Maeda K, Karin M & Hotamisligil GS 2002 A central role for JNK in obesity and insulin resistance. Nature 420 333-336.
-
(2002)
Nature
, vol.420
, pp. 333-336
-
-
Hirosumi, J.1
Tuncman, G.2
Chang, L.3
Gorgun, C.Z.4
Uysal, K.T.5
Maeda, K.6
Karin, M.7
Hotamisligil, G.S.8
-
9
-
-
0033772073
-
Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus
-
Horikawa Y, Oda N, Cox NJ, Li X, Orho-Melander M, Hara M, Hinokio Y, Lindner TH, Mashima H, Schwarz PE, Bosque-Plata L, Horikawa Y, Oda Y, Yoshiuchi I, Colilla S, Polonsky KS, Wei S, Concannon P, Iwasaki N, Schulze J, Baier LJ, Bogardus C, Groop L, Boerwinkle E, Hanis CL & Bell GI 2000 Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nature Genetics 26 163-175.
-
(2000)
Nature Genetics
, vol.26
, pp. 163-175
-
-
Horikawa, Y.1
Oda, N.2
Cox, N.J.3
Li, X.4
Orho-Melander, M.5
Hara, M.6
Hinokio, Y.7
Lindner, T.H.8
Mashima, H.9
Schwarz, P.E.10
Bosque-Plata, L.11
Horikawa, Y.12
Oda, Y.13
Yoshiuchi, I.14
Colilla, S.15
Polonsky, K.S.16
Wei, S.17
Concannon, P.18
Iwasaki, N.19
Schulze, J.20
Baier, L.J.21
Bogardus, C.22
Groop, L.23
Boerwinkle, E.24
Hanis, C.L.25
Bell, G.I.26
more..
-
10
-
-
0032875363
-
G alpha-q/11 protein plays a key role in insulin-induced glucose transport in 3T3-L1 adipocytes
-
Imamura T, Vollenweider P, Egawa K, Clodi M, Ishibashi K, Nakashima N, Ugi S, Adams JW, Brown JH & Olefsky JM 1999 G alpha-q/11 protein plays a key role in insulin-induced glucose transport in 3T3-L1 adipocytes. Molecular and Cellular Biology 19 6765-6774.
-
(1999)
Molecular and Cellular Biology
, vol.19
, pp. 6765-6774
-
-
Imamura, T.1
Vollenweider, P.2
Egawa, K.3
Clodi, M.4
Ishibashi, K.5
Nakashima, N.6
Ugi, S.7
Adams, J.W.8
Brown, J.H.9
Olefsky, J.M.10
-
11
-
-
0242384221
-
Physiological actions of regulators of G-protein signaling (RGS) proteins
-
Ishii M & Kurachi Y 2003 Physiological actions of regulators of G-protein signaling (RGS) proteins. Life Sciences 74 163-171.
-
(2003)
Life Sciences
, vol.74
, pp. 163-171
-
-
Ishii, M.1
Kurachi, Y.2
-
12
-
-
0030956371
-
Angiotensin II increases lipogenesis in 3T3-L1 and human adipose cells
-
Jones BH, Standridge MK & Moustaid N 1997 Angiotensin II increases lipogenesis in 3T3-L1 and human adipose cells. Endocrinology 138 1512-1519.
-
(1997)
Endocrinology
, vol.138
, pp. 1512-1519
-
-
Jones, B.H.1
Standridge, M.K.2
Moustaid, N.3
-
13
-
-
0034987312
-
The antihyperglycemic drug alpha-lipoic acid stimulates glucose uptake via both GLUT4 translocation and GLUT4 activation: Potential role of p38 mitogen-activated protein kinase in GLUT4 activation
-
Konrad D, Somwar R, Sweeney G, Yaworsky K, Hayashi M, Ramlal T & Klip A 2001 The antihyperglycemic drug alpha-lipoic acid stimulates glucose uptake via both GLUT4 translocation and GLUT4 activation: potential role of p38 mitogen-activated protein kinase in GLUT4 activation. Diabetes 50 1464-1471.
-
(2001)
Diabetes
, vol.50
, pp. 1464-1471
-
-
Konrad, D.1
Somwar, R.2
Sweeney, G.3
Yaworsky, K.4
Hayashi, M.5
Ramlal, T.6
Klip, A.7
-
14
-
-
0344406146
-
Mechanisms of the free fatty acid-induced increase in hepatic glucose production
-
Lam TK, Carpentier A, Lewis GF, van de Werve G, Fantus IG & Giacca A 2003 Mechanisms of the free fatty acid-induced increase in hepatic glucose production. American Journal of Physiology. Endocrinology and Metabolism 284 E863-E873.
-
(2003)
American Journal of Physiology. Endocrinology and Metabolism
, vol.284
-
-
Lam, T.K.1
Carpentier, A.2
Lewis, G.F.3
van de Werve, G.4
Fantus, I.G.5
Giacca, A.6
-
15
-
-
0037342152
-
Gene expression profiles of nondiabetic and diabetic obese mice suggest a role of hepatic lipogenic capacity in diabetes susceptibility
-
Lan H, Rabaglia ME, Stoehr JP, Nadler ST, Schueler KL, Zou F, Yandell BS & Attie AD 2003 Gene expression profiles of nondiabetic and diabetic obese mice suggest a role of hepatic lipogenic capacity in diabetes susceptibility. Diabetes 52 688-700.
-
(2003)
Diabetes
, vol.52
, pp. 688-700
-
-
Lan, H.1
Rabaglia, M.E.2
Stoehr, J.P.3
Nadler, S.T.4
Schueler, K.L.5
Zou, F.6
Yandell, B.S.7
Attie, A.D.8
-
16
-
-
0036217052
-
Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes
-
Lewis GF, Carpentier A, Adeli K & Giacca A 2002 Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes. Endocrine Reviews 23 201-229.
-
(2002)
Endocrine Reviews
, vol.23
, pp. 201-229
-
-
Lewis, G.F.1
Carpentier, A.2
Adeli, K.3
Giacca, A.4
-
17
-
-
0035488779
-
Characterization of the annexin I gene and evaluation of its role in type 2 diabetes
-
Lindgren CM, Nilsson A, Orho-Melander M, Almgren P & Groop LC 2001 Characterization of the annexin I gene and evaluation of its role in type 2 diabetes. Diabetes 50 2402-2405.
-
(2001)
Diabetes
, vol.50
, pp. 2402-2405
-
-
Lindgren, C.M.1
Nilsson, A.2
Orho-Melander, M.3
Almgren, P.4
Groop, L.C.5
-
18
-
-
0037335879
-
Plasminogen activator inhibitor type-1 inhibits insulin signaling by competing with alphavbeta3 integrin for vitronectin binding
-
Lopez-Alemany R, Redondo JM, Nagamine Y & Munoz-Canoves P 2003 Plasminogen activator inhibitor type-1 inhibits insulin signaling by competing with alphavbeta3 integrin for vitronectin binding. European Journal of Biochemistry 270 814-821.
-
(2003)
European Journal of Biochemistry
, vol.270
, pp. 814-821
-
-
Lopez-Alemany, R.1
Redondo, J.M.2
Nagamine, Y.3
Munoz-Canoves, P.4
-
19
-
-
0030914561
-
G-proteins and insulin signaling
-
Luft FC 1997 G-proteins and insulin signaling. Journal of Molecular Medicine 75 233-235.
-
(1997)
Journal of Molecular Medicine
, vol.75
, pp. 233-235
-
-
Luft, F.C.1
-
20
-
-
0036282431
-
Vitamin D binding protein gene and genetic susceptibility to type 2 diabetes mellitus in a Polish population
-
Malecki MT, Klupa T, Wanic K, Cyganek K, Frey J & Sieradzki J 2002 Vitamin D binding protein gene and genetic susceptibility to type 2 diabetes mellitus in a Polish population. Diabetes Research and Clinical Practice 57 99-104.
-
(2002)
Diabetes Research and Clinical Practice
, vol.57
, pp. 99-104
-
-
Malecki, M.T.1
Klupa, T.2
Wanic, K.3
Cyganek, K.4
Frey, J.5
Sieradzki, J.6
-
21
-
-
0035109055
-
Sortilin/neurotensin receptor-3: A new tool to investigate neurotensin signaling and cellular trafficking?
-
Mazella J 2001 Sortilin/neurotensin receptor-3: a new tool to investigate neurotensin signaling and cellular trafficking? Cell Signalling 13 1-6.
-
(2001)
Cell Signalling
, vol.13
, pp. 1-6
-
-
Mazella, J.1
-
22
-
-
0027993594
-
Annexin I as a potential inhibitor of insulin receptor protein tyrosine kinase
-
Melki V, Hullin F, Mazarguil H, Fauvel J, Ragab-Thomas JM & Chap H 1994 Annexin I as a potential inhibitor of insulin receptor protein tyrosine kinase. Biochemical and Biophysical Research Communications 203 813-819.
-
(1994)
Biochemical and Biophysical Research Communications
, vol.203
, pp. 813-819
-
-
Melki, V.1
Hullin, F.2
Mazarguil, H.3
Fauvel, J.4
Ragab-Thomas, J.M.5
Chap, H.6
-
23
-
-
0038054341
-
PGC-1 alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
-
Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, Ridderstrale M, Laurila E, Houstis N, Daly MJ, Patterson N, Mesirov JP, Golub TR, Tamayo P, Spiegelman B, Lander ES, Hirschhorn JN, Altshuler D & Groop LC 2003 PGC-1 alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nature Genetics 34 267-273.
-
(2003)
Nature Genetics
, vol.34
, pp. 267-273
-
-
Mootha, V.K.1
Lindgren, C.M.2
Eriksson, K.F.3
Subramanian, A.4
Sihag, S.5
Lehar, J.6
Puigserver, P.7
Carlsson, E.8
Ridderstrale, M.9
Laurila, E.10
Houstis, N.11
Daly, M.J.12
Patterson, N.13
Mesirov, J.P.14
Golub, T.R.15
Tamayo, P.16
Spiegelman, B.17
Lander, E.S.18
Hirschhorn, J.N.19
Altshuler, D.20
Groop, L.C.21
more..
-
24
-
-
0032488911
-
Sortilin is the major 110-kDa protein in GLUT4 vesicles from adipocytes
-
Morris NJ, Ross SA, Lane WS, Moestrup SK, Petersen CM, Keller SR & Lienhard GE 1998 Sortilin is the major 110-kDa protein in GLUT4 vesicles from adipocytes. Journal of Biological Chemistry 273 3582-3587.
-
(1998)
Journal of Biological Chemistry
, vol.273
, pp. 3582-3587
-
-
Morris, N.J.1
Ross, S.A.2
Lane, W.S.3
Moestrup, S.K.4
Petersen, C.M.5
Keller, S.R.6
Lienhard, G.E.7
-
25
-
-
0034633681
-
The expression of adipogenic genes is decreased in obesity and diabetes mellitus
-
Nadler ST, Stoehr JP, Schueler KL, Tanimoto G, Yandell BS & Attie AD 2000 The expression of adipogenic genes is decreased in obesity and diabetes mellitus. PNAS 97 11371-11376.
-
(2000)
PNAS
, vol.97
, pp. 11371-11376
-
-
Nadler, S.T.1
Stoehr, J.P.2
Schueler, K.L.3
Tanimoto, G.4
Yandell, B.S.5
Attie, A.D.6
-
26
-
-
0036077019
-
Effect of hyperinsulinemia and type 2 diabetes-like hyperglycemia on expression of hepatic cytochrome p450 and glutathione s-transferase isoforms in a New Zealand obese-derived mouse backcross population
-
Pass GJ, Becker W, Kluge R, Linnartz K, Plum L, Giesen K & Joost HG 2002 Effect of hyperinsulinemia and type 2 diabetes-like hyperglycemia on expression of hepatic cytochrome p450 and glutathione s-transferase isoforms in a New Zealand obese-derived mouse backcross population. Journal of Pharmacology and Experimental Therapeutics 302 442-450.
-
(2002)
Journal of Pharmacology and Experimental Therapeutics
, vol.302
, pp. 442-450
-
-
Pass, G.J.1
Becker, W.2
Kluge, R.3
Linnartz, K.4
Plum, L.5
Giesen, K.6
Joost, H.G.7
-
27
-
-
0037026745
-
Pathogenesis of skeletal muscle insulin resistance in type 2 diabetes mellitus
-
Petersen KF & Shulman GI 2002 Pathogenesis of skeletal muscle insulin resistance in type 2 diabetes mellitus. American Journal of Cardiology 90 11 G-18 G.
-
(2002)
American Journal of Cardiology
, vol.90
-
-
Petersen, K.F.1
Shulman, G.I.2
-
28
-
-
0035684378
-
A model for measurement error for gene expression arrays
-
Rocke DM & Durbin B 2001 A model for measurement error for gene expression arrays. Journal of Computational Biology 8 557-569.
-
(2001)
Journal of Computational Biology
, vol.8
, pp. 557-569
-
-
Rocke, D.M.1
Durbin, B.2
-
29
-
-
0038724906
-
Microarray profiling of human skeletal muscle reveals that insulin regulates approximately 800 genes during a hyperinsulinemic clamp
-
Rome S, Clement K, Rabasa-Lhoret R, Loizon E, Poitou C, Barsh GS, Riou JP, Laville M & Vidal H 2003 Microarray profiling of human skeletal muscle reveals that insulin regulates approximately 800 genes during a hyperinsulinemic clamp. Journal of Biological Chemistry 278 18063-18068.
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 18063-18068
-
-
Rome, S.1
Clement, K.2
Rabasa-Lhoret, R.3
Loizon, E.4
Poitou, C.5
Barsh, G.S.6
Riou, J.P.7
Laville, M.8
Vidal, H.9
-
30
-
-
0035936763
-
New perspectives into the molecular pathogenesis and treatment of type 2 diabetes
-
Saltiel AR 2001 New perspectives into the molecular pathogenesis and treatment of type 2 diabetes. Cell 104 517-529.
-
(2001)
Cell
, vol.104
, pp. 517-529
-
-
Saltiel, A.R.1
-
31
-
-
0036295566
-
Protein kinase C and lipid-induced insulin resistance in skeletal muscle
-
Schmitz-Peiffer C 2002 Protein kinase C and lipid-induced insulin resistance in skeletal muscle. Annals of the New York Academy of Sciences 967 146-157.
-
(2002)
Annals of the New York Academy of Sciences
, vol.967
, pp. 146-157
-
-
Schmitz-Peiffer, C.1
-
32
-
-
0036266251
-
Gene expression profile in skeletal muscle of type 2 diabetes and the effect of insulin treatment
-
Sreekumar R, Halvatsiotis P, Schimke JC & Nair KS 2002 Gene expression profile in skeletal muscle of type 2 diabetes and the effect of insulin treatment. Diabetes 51 1913-1920.
-
(2002)
Diabetes
, vol.51
, pp. 1913-1920
-
-
Sreekumar, R.1
Halvatsiotis, P.2
Schimke, J.C.3
Nair, K.S.4
-
33
-
-
0035458548
-
Calpains play a role in insulin secretion and action
-
Sreenan SK, Zhou YP, Otani K, Hansen PA, Currie KP, Pan CY, Lee JP, Ostrega DM, Pugh W, Horikawa Y, Cox NJ, Hanis CL, Burant CF, Fox AP, Bell GI & Polonsky KS 2001 Calpains play a role in insulin secretion and action. Diabetes 50 2013-2020.
-
(2001)
Diabetes
, vol.50
, pp. 2013-2020
-
-
Sreenan, S.K.1
Zhou, Y.P.2
Otani, K.3
Hansen, P.A.4
Currie, K.P.5
Pan, C.Y.6
Lee, J.P.7
Ostrega, D.M.8
Pugh, W.9
Horikawa, Y.10
Cox, N.J.11
Hanis, C.L.12
Burant, C.F.13
Fox, A.P.14
Bell, G.I.15
Polonsky, K.S.16
-
34
-
-
0033537853
-
An inhibitor of p38 mitogen-activated protein kinase prevents insulin-stimulated glucose transport but not glucose transporter translocation in 3T3-L1 adipocytes and L6 myotubes
-
Sweeney G, Somwar R, Ramlal T, Volchuk A, Ueyama A & Klip A 1999 An inhibitor of p38 mitogen-activated protein kinase prevents insulin-stimulated glucose transport but not glucose transporter translocation in 3T3-L1 adipocytes and L6 myotubes. Journal of Biological Chemistry 274 10071-10078.
-
(1999)
Journal of Biological Chemistry
, vol.274
, pp. 10071-10078
-
-
Sweeney, G.1
Somwar, R.2
Ramlal, T.3
Volchuk, A.4
Ueyama, A.5
Klip, A.6
-
35
-
-
0025098444
-
Effects of testosterone and growth hormone treatment on hepatic microsomal P450 expression in the diabetic rat
-
Thummel KE & Schenkman JB 1990 Effects of testosterone and growth hormone treatment on hepatic microsomal P450 expression in the diabetic rat. Molecular Pharmacology 37 119-129.
-
(1990)
Molecular Pharmacology
, vol.37
, pp. 119-129
-
-
Thummel, K.E.1
Schenkman, J.B.2
-
36
-
-
0036435899
-
Microarray profiling of skeletal muscle tissues from equally obese, non-diabetic insulin-sensitive and insulin-resistant Pima Indians
-
Yang X, Pratley RE, Tokraks S, Bogardus C & Permana PA 2002 Microarray profiling of skeletal muscle tissues from equally obese, non-diabetic insulin-sensitive and insulin-resistant Pima Indians. Diabetologia 45 1584-1593.
-
(2002)
Diabetologia
, vol.45
, pp. 1584-1593
-
-
Yang, X.1
Pratley, R.E.2
Tokraks, S.3
Bogardus, C.4
Permana, P.A.5
|