메뉴 건너뛰기




Volumn 18, Issue 3-4, 2004, Pages 347-351

Current challenges in human embryonic stem cell research: Directed differentiation and transplantation tolerance

Author keywords

Differentiation; Embryonic stem cells; Gene transfer; mRNA electroporation; Tolerance; Transplantation

Indexed keywords

ALLOGENEIC STEM CELL TRANSPLANTATION; ANIMAL EXPERIMENT; ARTICLE; BLASTOCYST; CELL DIFFERENTIATION; CELL TYPE; CLINICAL PROTOCOL; EMBRYONIC STEM CELL; GENE TRANSFER; HUMAN; HUMAN CELL; IMMUNOLOGICAL TOLERANCE; IMMUNOMODULATION; INNER CELL MASS; MEDICAL RESEARCH; NONHUMAN; STEM CELL TRANSPLANTATION; CYTOLOGY; EMBRYO; METABOLISM; REVIEW; STEM CELL; TRANSPLANTATION TOLERANCE;

EID: 17844404239     PISSN: 0393974X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (17)

References (49)
  • 1
    • 5044241544 scopus 로고    scopus 로고
    • Therapeutic potential of stem cells in central nervous system regeneration
    • Webber DJ, Minger SL. Therapeutic potential of stem cells in central nervous system regeneration. Current Opinion in Investigational Drugs 2004; 5: 714-9.
    • (2004) Current Opinion in Investigational Drugs , vol.5 , pp. 714-719
    • Webber, D.J.1    Minger, S.L.2
  • 2
    • 3042758642 scopus 로고    scopus 로고
    • Stem-cell therapy for diabetes mellitus
    • Hussain MA, Theise ND. Stem-cell therapy for diabetes mellitus. Lancet 2004; 364: 203-5.
    • (2004) Lancet , vol.364 , pp. 203-205
    • Hussain, M.A.1    Theise, N.D.2
  • 3
    • 3142554538 scopus 로고    scopus 로고
    • Stem cells and repair of the heart
    • Mathur A, Martin JF. Stem cells and repair of the heart. Lancet 2004; 364: 183-92.
    • (2004) Lancet , vol.364 , pp. 183-192
    • Mathur, A.1    Martin, J.F.2
  • 4
    • 0034101804 scopus 로고    scopus 로고
    • Embryonic stem cell lines from human blastocysts: Somatic differentiation in vitro
    • Reubinoff BE, Pera MF, Fong CY, Trounson A, Bongso A. Embryonic stem cell lines from human blastocysts: Somatic differentiation in vitro. Nat Biotechnol 2000; 18: 399-404.
    • (2000) Nat. Biotechnol. , vol.18 , pp. 399-404
    • Reubinoff, B.E.1    Pera, M.F.2    Fong, C.Y.3    Trounson, A.4    Bongso, A.5
  • 5
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al. Embryonic stem cell lines derived from human blastocysts. Science 1998; 282: 1145-47.
    • (1998) Science , vol.282 , pp. 1145-1147
    • Thomson, J.A.1    Itskovitz-Eldor, J.2    Shapiro, S.S.3
  • 6
    • 0348103716 scopus 로고    scopus 로고
    • Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells
    • Draper JS, Smith K, Gokhale P, et al. Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells. Nat Biotechnol 2004; 22: 53-4.
    • (2004) Nat. Biotechnol. , vol.22 , pp. 53-54
    • Draper, J.S.1    Smith, K.2    Gokhale, P.3
  • 7
    • 0038724202 scopus 로고    scopus 로고
    • Human feeder layers for human embryonic stem cells
    • Amit M, Margulets V, Segev H, et al. Human feeder layers for human embryonic stem cells. Biology of Reproduction 2003; 68: 2150-6.
    • (2003) Biology of Reproduction , vol.68 , pp. 2150-2156
    • Amit, M.1    Margulets, V.2    Segev, H.3
  • 8
    • 0036714330 scopus 로고    scopus 로고
    • Human feeders support prolonged undifferentiated growth of human inner cell masses and embryonic stem cells
    • Richards M, Fong CY, Chan WK, Wong PC, Bongso A. Human feeders support prolonged undifferentiated growth of human inner cell masses and embryonic stem cells. Nat Biotechnol 2002; 20: 933-6.
    • (2002) Nat. Biotechnol. , vol.20 , pp. 933-936
    • Richards, M.1    Fong, C.Y.2    Chan, W.K.3    Wong, P.C.4    Bongso, A.5
  • 9
    • 10744225452 scopus 로고    scopus 로고
    • A culture system using human foreskin fibroblasts as feeder cells allows production of human embryonic stem cells
    • Hovatta O, Mikkola M, Gertow K, et al. A culture system using human foreskin fibroblasts as feeder cells allows production of human embryonic stem cells. Human Reproduction 2003; 18: 1404-9.
    • (2003) Human Reproduction , vol.18 , pp. 1404-1409
    • Hovatta, O.1    Mikkola, M.2    Gertow, K.3
  • 10
    • 0942298178 scopus 로고    scopus 로고
    • Long-term culture of human embryonic stem cells in feeder-free conditions
    • Rosler ES, Fisk GJ, Ares X, et al. Long-term culture of human embryonic stem cells in feeder-free conditions. Developmental Dynamics 2004; 229: 259-74.
    • (2004) Developmental Dynamics , vol.229 , pp. 259-274
    • Rosler, E.S.1    Fisk, G.J.2    Ares, X.3
  • 11
    • 0034794417 scopus 로고    scopus 로고
    • Feeder-free growth of undifferentiated human embryonic stem cells
    • Xu C, Inokuma MS, Denham J, et al. Feeder-free growth of undifferentiated human embryonic stem cells. Nat Biotechnol 2001; 19: 971-4.
    • (2001) Nat. Biotechnol. , vol.19 , pp. 971-974
    • Xu, C.1    Inokuma, M.S.2    Denham, J.3
  • 12
    • 0038300672 scopus 로고    scopus 로고
    • Human embryonic stem cells develop into multiple types of cardiac myocytes: Action potential characterization
    • He JQ, Ma Y, Lee Y, Thomson JA, Kamp TJ. Human embryonic stem cells develop into multiple types of cardiac myocytes: Action potential characterization. Circulation Research 2003; 93: 32-9.
    • (2003) Circulation Research , vol.93 , pp. 32-39
    • He, J.Q.1    Ma, Y.2    Lee, Y.3    Thomson, J.A.4    Kamp, T.J.5
  • 13
    • 0034136393 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers
    • Itskovitz-Eldor J, Schuldiner M, Karsenti D, et al. Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers. Molecular Medicine 2000; 6: 88-95.
    • (2000) Molecular Medicine , vol.6 , pp. 88-95
    • Itskovitz-Eldor, J.1    Schuldiner, M.2    Karsenti, D.3
  • 14
    • 0034904645 scopus 로고    scopus 로고
    • Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes
    • Kehat I, Kenyagin-Karsenti D, Snir M, et al. Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes. J Clin Invest 2001; 108: 407-14.
    • (2001) J. Clin. Invest. , vol.108 , pp. 407-414
    • Kehat, I.1    Kenyagin-Karsenti, D.2    Snir, M.3
  • 16
    • 1842533535 scopus 로고    scopus 로고
    • Spontaneous differentiation of germ cells from human embryonic stem cells in vitro
    • Clark AT, Bodnar MS, Fox M, et al. Spontaneous differentiation of germ cells from human embryonic stem cells in vitro. Human Molecular Genetics 2004; 13: 727-39.
    • (2004) Human Molecular Genetics , vol.13 , pp. 727-739
    • Clark, A.T.1    Bodnar, M.S.2    Fox, M.3
  • 18
    • 9644282186 scopus 로고    scopus 로고
    • Differentiation and isolation of hepatic-like cells from human embryonic stem cells
    • Lavon N, Yanuka O, Benvenisty N. Differentiation and isolation of hepatic-like cells from human embryonic stem cells. Differentiation 2004; 72: 230-8.
    • (2004) Differentiation , vol.72 , pp. 230-238
    • Lavon, N.1    Yanuka, O.2    Benvenisty, N.3
  • 19
    • 0037144701 scopus 로고    scopus 로고
    • Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells
    • Xu C, Police S, Rao N, Carpenter MK. Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells. Circulation Res 2002; 91: 501-8.
    • (2002) Circulation Res. , vol.91 , pp. 501-508
    • Xu, C.1    Police, S.2    Rao, N.3    Carpenter, M.K.4
  • 20
    • 0037871588 scopus 로고    scopus 로고
    • Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells
    • Chadwick K, Wang L, Li L, et al. Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells. Blood 2003; 102: 906-15.
    • (2003) Blood , vol.102 , pp. 906-915
    • Chadwick, K.1    Wang, L.2    Li, L.3
  • 21
    • 1642306055 scopus 로고    scopus 로고
    • VEGF-A165 augments erythropoietic development from human embryonic stem cells
    • Cerdan C, Rouleau A, Bhatia M. VEGF-A165 augments erythropoietic development from human embryonic stem cells. Blood 2004; 103: 2504-12.
    • (2004) Blood , vol.103 , pp. 2504-2512
    • Cerdan, C.1    Rouleau, A.2    Bhatia, M.3
  • 23
    • 11144354441 scopus 로고    scopus 로고
    • Generation of dopaminergic neurons in vitro from human embryonic stem cells treated with neurotrophic factors
    • Park S, Lee KS, Lee YJ, et al. Generation of dopaminergic neurons in vitro from human embryonic stem cells treated with neurotrophic factors. Neuroscience Letters 2004; 359: 99-103.
    • (2004) Neuroscience Letters , vol.359 , pp. 99-103
    • Park, S.1    Lee, K.S.2    Lee, Y.J.3
  • 24
    • 0035929503 scopus 로고    scopus 로고
    • Induced neuronal differentiation of human embryonic stem cells
    • Schuldiner M, Eiges R, Eden A, et al. Induced neuronal differentiation of human embryonic stem cells. Brain Res 2001; 913: 201-5.
    • (2001) Brain Res. , vol.913 , pp. 201-205
    • Schuldiner, M.1    Eiges, R.2    Eden, A.3
  • 25
    • 0035200623 scopus 로고    scopus 로고
    • In vitro differentiation of transplantable neural precursors from human embryonic stem cells
    • Zhang SC, Wernig M, Duncan ID, Brustle O, Thomson JA. In vitro differentiation of transplantable neural precursors from human embryonic stem cells. Nat Biotechnol 2001; 19: 1129-33.
    • (2001) Nat. Biotechnol. , vol.19 , pp. 1129-1133
    • Zhang, S.C.1    Wernig, M.2    Duncan, I.D.3    Brustle, O.4    Thomson, J.A.5
  • 27
    • 0038638343 scopus 로고    scopus 로고
    • In vitro osteogenic differentiation of human ES cells
    • Sottile V, Thomson A, McWhir J. In vitro osteogenic differentiation of human ES cells. Cloning and Stem Cells 2003; 5: 149-55.
    • (2003) Cloning and Stem Cells , vol.5 , pp. 149-155
    • Sottile, V.1    Thomson, A.2    McWhir, J.3
  • 29
    • 3543001036 scopus 로고    scopus 로고
    • Efficient transfection of embryonic and adult stem cells
    • Lakshmipathy U, Pelacho B, Sudo K, et al. Efficient transfection of embryonic and adult stem cells. Stem Cells 2004; 22: 531-43.
    • (2004) Stem Cells , vol.22 , pp. 531-543
    • Lakshmipathy, U.1    Pelacho, B.2    Sudo, K.3
  • 30
  • 31
    • 0037303676 scopus 로고    scopus 로고
    • Stable genetic modification of human embryonic stem cells by lentiviral vectors
    • Gropp M, Itsykson P, Singer O, et al. Stable genetic modification of human embryonic stem cells by lentiviral vectors. Molecular Therapy 2003; 7: 281-7.
    • (2003) Molecular Therapy , vol.7 , pp. 281-287
    • Gropp, M.1    Itsykson, P.2    Singer, O.3
  • 32
    • 0037240651 scopus 로고    scopus 로고
    • High-level sustained transgene expression in human embryonic stem cells using lentiviral vectors
    • Ma Y, Ramezani A, Lewis R, Hawley RG, Thomson JA. High-level sustained transgene expression in human embryonic stem cells using lentiviral vectors. Stem Cells 2003; 21: 111-7.
    • (2003) Stem Cells , vol.21 , pp. 111-117
    • Ma, Y.1    Ramezani, A.2    Lewis, R.3    Hawley, R.G.4    Thomson, J.A.5
  • 33
    • 0037103350 scopus 로고    scopus 로고
    • Messenger RNA electroporation of human monocytes, followed by rapid in vitro differentiation, leads to highly stimulatory antigen-loaded mature dendritic cells
    • Ponsaerts P, Van den Bosch G, Cools N, et al. Messenger RNA electroporation of human monocytes, followed by rapid in vitro differentiation, leads to highly stimulatory antigen-loaded mature dendritic cells. J Immunol 2002; 169: 1669-75.
    • (2002) J. Immunol. , vol.169 , pp. 1669-1675
    • Ponsaerts, P.1    Van den Bosch, G.2    Cools, N.3
  • 34
    • 0036049777 scopus 로고    scopus 로고
    • mRNA-electroporated mature dendritic cells retain transgene expression, phenotypical properties and stimulatory capacity after cryopreservation
    • Ponsaerts P, Van Tendeloo VF, Cools N, et al. mRNA-electroporated mature dendritic cells retain transgene expression, phenotypical properties and stimulatory capacity after cryopreservation. Leukemia 2002; 16: 1324-30.
    • (2002) Leukemia , vol.16 , pp. 1324-1330
    • Ponsaerts, P.1    Van Tendeloo, V.F.2    Cools, N.3
  • 35
    • 0033839608 scopus 로고    scopus 로고
    • High-level transgene expression in primary human T lymphocytes and adult bone marrow CD34+ cells via electroporation-mediated gene delivery
    • Van Tendeloo VF, Willems R, Ponsaerts P, et al. High-level transgene expression in primary human T lymphocytes and adult bone marrow CD34+ cells via electroporation-mediated gene delivery. Gene Therapy 2000; 7: 1431-7.
    • (2000) Gene Therapy , vol.7 , pp. 1431-1437
    • Van Tendeloo, V.F.1    Willems, R.2    Ponsaerts, P.3
  • 37
    • 0037062920 scopus 로고    scopus 로고
    • Emerging clinical applications of RNA
    • Sullenger BA, Gilboa E. Emerging clinical applications of RNA. Nature 2002; 418: 252-8.
    • (2002) Nature , vol.418 , pp. 252-258
    • Sullenger, B.A.1    Gilboa, E.2
  • 38
    • 7244238185 scopus 로고    scopus 로고
    • Messenger RNA electroporation is highly efficient in mouse embryonic stem cells: Successful FLPe- and Cre-mediated recombination
    • (in press)
    • Ponsaerts P, Brown JP, Van Den Plas D, et al. Messenger RNA electroporation is highly efficient in mouse embryonic stem cells: Successful FLPe- and Cre-mediated recombination. Gene Therapy 2004 (in press).
    • (2004) Gene Therapy
    • Ponsaerts, P.1    Brown, J.P.2    Van Den Plas, D.3
  • 41
    • 0036348187 scopus 로고    scopus 로고
    • Pathways of allorecognition: Implications for transplantation tolerance
    • Game DS, Lechler RI. Pathways of allorecognition: Implications for transplantation tolerance. Transpl Immunol 2002; 10: 101-8.
    • (2002) Transpl. Immunol. , vol.10 , pp. 101-108
    • Game, D.S.1    Lechler, R.I.2
  • 43
    • 12144286557 scopus 로고    scopus 로고
    • Evidence of a pluripotent human embryonic stem cell line derived from a cloned blastocyst
    • Hwang WS, Ryu YJ, Park JH, et al. Evidence of a pluripotent human embryonic stem cell line derived from a cloned blastocyst. Science 2004; 303: 1669-74.
    • (2004) Science , vol.303 , pp. 1669-1674
    • Hwang, W.S.1    Ryu, Y.J.2    Park, J.H.3
  • 44
    • 0037162551 scopus 로고    scopus 로고
    • Characterization of the expression of MHC proteins in human embryonic stem cells
    • Drukker M, Katz G, Urbach A, et al. Characterization of the expression of MHC proteins in human embryonic stem cells. Proc Nat Acad Sci USA 2002; 99: 9864-9.
    • (2002) Proc. Nat. Acad. Sci. USA , vol.99 , pp. 9864-9869
    • Drukker, M.1    Katz, G.2    Urbach, A.3
  • 45
    • 0037336820 scopus 로고    scopus 로고
    • Homologous recombination in human embryonic stem cells
    • Zwaka TP, Thomson JA. Homologous recombination in human embryonic stem cells. Nat Biotechnol 2003; 21: 319-21.
    • (2003) Nat. Biotechnol. , vol.21 , pp. 319-321
    • Zwaka, T.P.1    Thomson, J.A.2
  • 46
    • 3042767903 scopus 로고    scopus 로고
    • Natural killer T cells as targets for immunotherapy of autoimmune diseases
    • Van Kaer L. Natural killer T cells as targets for immunotherapy of autoimmune diseases. Immunology and Cell Biology 2004; 82: 315-22.
    • (2004) Immunology and Cell Biology , vol.82 , pp. 315-322
    • Van Kaer, L.1
  • 47
    • 2542568696 scopus 로고    scopus 로고
    • Recognition of nonpeptide antigens by human V gamma 9V delta 2 T cells requires contact with cells of human origin
    • Green AE, Lissina A, Hutchinson SL, et al. Recognition of nonpeptide antigens by human V gamma 9V delta 2 T cells requires contact with cells of human origin. Clin Exp Immunol 2004; 136: 472-82.
    • (2004) Clin. Exp. Immunol. , vol.136 , pp. 472-482
    • Green, A.E.1    Lissina, A.2    Hutchinson, S.L.3
  • 49
    • 0141853311 scopus 로고    scopus 로고
    • Immune regulation by regulatory T cells: Implications for transplantation
    • Jonuleit H, Adema G, Schmitt E. Immune regulation by regulatory T cells: Implications for transplantation. Transpl Immunol 2008; 11: 267-76.
    • (2008) Transpl. Immunol. , vol.11 , pp. 267-276
    • Jonuleit, H.1    Adema, G.2    Schmitt, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.