SIR1, an upstream component in auxin signaling identified by chemical genetics

Science

Volumn 301, Issue 5636, 2003, Pages 1107-1110

  Zhao, Yunde ^a   Dai, Xinhua ^a   Blackwell, Helen E ^b,d   Schreiber, Stuart L ^b   Chory, Joanne ^c  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b HARVARD UNIVERSITY   (United States)

^c SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^d UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENES; HORMONES; MOLECULES; NEUROLOGY;

MUTANTS;

GENETIC ENGINEERING;

AUXIN; GENE PRODUCT; MUTANT PROTEIN; PROTEIN SIR1; SIRTINOL; THIOSULFATE SULFURTRANSFERASE; UBIQUITIN; UNCLASSIFIED DRUG; VEGETABLE PROTEIN;

GENETICS; HORMONE; PLANT;

ARTICLE; ENZYME ACTIVITY; ENZYME STRUCTURE; GENETIC ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PLANT GENETICS; PLANT GROWTH; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; ARABIDOPSIS; ARABIDOPSIS PROTEINS; BENZAMIDES; BINDING SITES; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, PLANT; GENES, PLANT; GENES, REPORTER; INDOLEACETIC ACIDS; MOLECULAR SEQUENCE DATA; MUTATION; NAPHTHOLS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; PLANT LEAVES; PLANT ROOTS; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION; SIRTUINS; TRANSCRIPTION, GENETIC;

EMBRYOPHYTA;

EID: 0042431612     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1084161     Document Type: Article

References (29)

1. W. M. Gray, S. Kepinski, D. Rouse, O. Leyser, M. Estelle, Nature 414, 271 (2001).
2. L. Hobbie, M. Estelle, Plant Cell Environ. 17, 525 (1994).
3. G. Hagen, T. J. Guilfoyle, Mol. Cell. Biol. 5, 1197 (1985).
4. A. Theologis, T. V. Huynh, R. W. Davis, J. Mol. Biol. 183, 53 (1985).
5. H. Hellmann, M. Estelle, Science 297, 793 (2002).
6. J. Friml, K. Palme, Plant Mol. Biol. 49, 273 (2002).
7. D. Schroeder et al., Curr. Biol. 12, 1462 (2002).
8. C. M. Grozinger, E. D. Chao, H. E. Blackwell, D. Moazed, S. L. Schreiber, J. Biol. Chem. 276, 38837 (2001).
9. S. Sabatini et al., Cell 99, 463 (1999).
10. Materials and methods are available as supporting material on Science Online.
11. S. Abet, P. W. Oetter, A. Theologis, Proc. Natl. Acad. Sci. U.S.A. 91, 326 (1994).
12. H. M. Leyser et al., Nature 364, 161 (1993).
13. J. J. King, D. P. Stimart, R. H. Fisher, A. B. Bleecker, Plant Cell 7, 2023 (1995).
14. Y. Zhao et al., Science 291, 306 (2001).
15. C. Lincoln, J. H. Britton, M. Estelle, Plant Cell 2, 1071 (1990).
16. D. Reinhardt, T. Mandel, C. Kuhlemeier, Plant Cell 12, 507 (2000).
17. C. Timpte, A. K. Wilson, M. Estelle, Genetics 138, 1239 (1994).
18. M. Ruegger et al., Genes Dev. 12, 198 (1998).
19. R. M. Harper et al., Plant Cell 12, 757 (2000).
20. M. J. Bennett et al., Science 273, 948 (1996).
21. C. Luschnig, R. A. Gaxiola, P. Grisafi, G. R. Fink, Genes Dev. 12, 2175 (1998).
22. M. Ruegger et al., Plant Cell 9, 745 (1997).
23. J. Nieder et al., in Sulphur Metabolism in Higher Plants, W. J. Cram, Ed. (Backhuys, Leiden, Netherlands, 1997), pp. 275-277.
24. K. Furukawa, N. Mizushima, T. Noda, Y. Ohsumi, J. Biol. Chem. 275, 7462 (2000).
25. M. W. Lake, M. M. Wuebbens, K. V. Rajagopalan, H. Schindelin, Nature 414, 325 (2001).
26. D. Bordo, P. Bork, EMBO Rep. 3, 741 (2002).
27. J. W. Reed, Trends Plant Sci. 6, 420 (2001).
28. P. Zacchi et al., Nature 419, 853 (2002).
29. We thank J. Perry, J. Ecker, M. Yanofsky, and J. Nemhauser for their comments on the manuscript and M. Estelle for providing AXR3-NT-GUS transgenic plants. Supported by University of California-San Diego internal funds; NIH grant nos. 1R01GM68631-01 (Y.Z.) and 2R01GM52413 (J.C.); and the HHMI (J.C. and S.L.S.). H.E.B. was supported by a Jane Coffin Childs Memorial Fund Postdoctoral Fellowship. J.C. and S.LS. are investigators of the HHMI.