The mechanism of selective purine C-nitration revealed: NMR studies demonstrate formation and radical rearrangement of an N7-nitramine intermediate

Journal of the American Chemical Society

Volumn 127, Issue 16, 2005, Pages 5957-5963

  Rodenko, Boris ^a   Koch, Melle ^a   Van Der Burg, Alida M ^a   Wanner, Martin J ^a   Koomen, Gerrit Jan ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIUM COMPOUNDS; ELECTRON TRAPS; NEGATIVE IONS; NITRATION; NUCLEAR MAGNETIC RESONANCE; SUBSTITUTION REACTIONS;

ELUCIDATION; PHARMACOPHORES; PURINE; RADICAL TRAPPING;

AROMATIC COMPOUNDS;

6 CHLOROPURINE; ANILINE DERIVATIVE; NITRAMINE; NITRATE; PURINE C2; PURINE DERIVATIVE; RADICAL; TETRABUTYLAMMONIUM; TRIFLUOROACETIC ACID; TRIFLUOROACETIC ANHYDRIDE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODEL; CHEMICAL STRUCTURE; NITRATION; NITROGEN NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHARMACOPHORE; PROTON NUCLEAR MAGNETIC RESONANCE; RADICAL REACTION; REACTION ANALYSIS; SUBSTITUTION REACTION;

ANILINE COMPOUNDS; NITROBENZENES; NITROGEN ISOTOPES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PURINES; QUATERNARY AMMONIUM COMPOUNDS; TRIFLUOROACETIC ACID;

EID: 17744397327     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja042590x     Document Type: Article

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