Probing prime substrate binding sites of human dipeptidyl peptidase-IV using competitive substrate approach

Archives of Biochemistry and Biophysics

Volumn 436, Issue 2, 2005, Pages 367-376

  Kopcho, Lisa M ^a   Kim, Young B ^a   Wang, Aiying ^a   Liu, Margaret A ^a   Kirby, Mark S ^a   Marcinkeviciene, Jovita ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

GLP 1; His Ala pNA; Human DPP IV; Kinetic mechanism; Novel sites

Indexed keywords

ALANINE; CHYMOTRYPSIN; DIPEPTIDYL PEPTIDASE IV; ELASTASE; HISTIDINE;

ACYLATION; ANIMAL CELL; ARTICLE; BINDING SITE; CALCULATION; CATALYSIS; CONTROLLED STUDY; DEACYLATION; ENZYME SUBSTRATE; MICROSCOPY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; REACTION ANALYSIS; STEADY STATE; TEMPERATURE; THERMODYNAMICS; VISCOSITY;

EID: 17744391563     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.abb.2005.02.015     Document Type: Article

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