(5-Arylfuran-2-ylcarbonyl)guanidines as cardioprotectives through the inhibition of Na+/H+ exchanger isoform-1

Journal of Medicinal Chemistry

Volumn 48, Issue 8, 2005, Pages 2882-2891

  Lee, Sunkyung ^a   Yi, Kyu Yang ^a   Hwang, Sun Kyung ^a   Lee, Byung Ho ^a   Yoo, Sung Eun ^a   Lee, Kyunghee ^b  

^a Korea Research Institute of Chemical Technology   (South Korea)

^b Yuyu Pharma Inc   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

(5 FURAN 2 YLCARBONYL)GUANIDINE DERIVATIVE; (5 PHENYLFURAN 2 YLCARBONYL)GUANIDINE METHANESULFONATE; 2 METHOXY 5 CHLOROPHENYL DERIVATIVE; AMILORIDE; CARIPORIDE; GUANIDINE DERIVATIVE; PHENYL GROUP; SODIUM PROTON EXCHANGE PROTEIN 1; UNCLASSIFIED DRUG; ZONIPORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BOLUS INJECTION; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; ENZYME ACTIVITY; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE CONTRACTILE FORCE; HEART PROTECTION; IC 50; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; RAT; REPERFUSION INJURY;

ANIMALS; CARDIOTONIC AGENTS; CATION TRANSPORT PROTEINS; CELL LINE; FURANS; GUANIDINES; HUMANS; MEMBRANE PROTEINS; MYOCARDIAL INFARCTION; PROTEIN ISOFORMS; RATS; SODIUM-HYDROGEN ANTIPORTER; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 17544378824     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0492305     Document Type: Article

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