Accumulation of intestinal intraepithelial lymphocytes in association with lack of polymeric immunoglobulin receptor

European Journal of Immunology

Volumn 35, Issue 4, 2005, Pages 1211-1219

  Yamazaki, Ken Ichi ^a   Shimada, Shin Ichiro ^b   Kato Nagaoka, Noriko ^b   Soga, Hiroyuki ^c   Itoh, Tsunetoshi ^c   Nanno, Masanobu ^b  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^b YAKULT CENTRAL INSTITUTE FOR MICROBIOLOGICAL RESEARCH   (Japan)

^c TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Cytotoxic activity; IEL; Intestinal microorganism; pIgR; TCR

Indexed keywords

CD8 ANTIGEN; GRANZYME B; IMMUNOGLOBULIN A; MESSENGER RNA; PERFORIN; SECRETORY COMPONENT; SERINE PROTEINASE; T LYMPHOCYTE RECEPTOR BETA CHAIN; T LYMPHOCYTE RECEPTOR DELTA CHAIN;

ADOPTIVE TRANSFER; AIRWAY; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; GERMFREE ANIMAL; IMMUNOGLOBULIN DEFICIENCY; LACRIMAL FLUID; LACTATION; LAMINA PROPRIA; LYMPHOCYTE; LYMPHOCYTE MIGRATION; LYMPHOCYTE PROLIFERATION; MAMMARY GLAND; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; SALIVARY GLAND; SMALL INTESTINE MUCOSA;

ANIMALS; GENE EXPRESSION; GERM-FREE LIFE; INTESTINAL MUCOSA; LYMPHOCYTES; MICE; MICE, TRANSGENIC; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, POLYMERIC IMMUNOGLOBULIN; T-LYMPHOCYTES, CYTOTOXIC;

EID: 17444423280     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200425627     Document Type: Article

References (39)

1. McLeod, R. and Mack, D. G., Secretory IgA specific for Toxoplasma gondii. J. Immunol. 1986. 136: 2640-2643.
2. Keren, D. F., Brown, J. E., McDonald, R. A. and Wassef, J. S., Secretory immunoglobulin A response to Shiga toxin in rabbits: kinetics of the initial mucosal immune response and inhibition of toxicity in vitro and in vivo. Infect. Immun. 1989. 57: 1885-1889.
3. Winner III, L., Mack, J., Weltzin, R., Mekalanos, J. J., Kraehenbuhl, J.-P. and Neutra, M. R., New model for analysis of mucosal immunity: Intestinal secretion of specific monoclonal immunoglobulin A from hybridoma tumors protects against Vibrio cholera infection. Infect. Immun. 1991. 59: 977-982.
4. Klaasen, H. L., van der Hejden, P. J., Stok, W., Poelma, F. G., Koopman, J. P., van den Brink, M. E., Bakker, M. H., Eling, W. M. and Beynen, A. C., Apathogenic, intestinal, segmented filamentous bacteria stimulate the mucosal immune system of mice. Infect. Immun. 1993. 61: 303-306.
5. Shroff, K. E., Meslin, K. and Cebra, J. J., Commensal enteric bacteria engender a self-limiting humoral mucosal immune response while permanently colonizing the gut. Infect. Immun. 1995. 63: 3904-3913.
6. Macpherson, A. J. and Uhr, T., Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria. Science 2004. 303: 1662-1665.
7. Fernandez, M. I., Pedron, T., Tournebize, R., Olivo-Marin, J.-C., Sansonetti, P. J. and Phalipon, A., Anti-inflammatory role for intracellular dimeric immunoglobulin A by neutralization of lipopolysaccharide in epithelial cells. Immunity 2003. 18: 739-749.
8. Robinson, J. K., Blanchard, T. G., Levine, A. D., Emancipator, S. N. and Lamm, M. E., A mucosal IgA-mediated excretory immune system in vivo. J. Immunol. 2001. 166: 3688-3692.
9. London, S. D., Cebra, J. J. and Rubin, D. H., Intraepithelial lymphocytes contain virus-specific, MHC-restricted cytotoxic cell precursors after gut mucosal immunization with reovirus serotype 1/Lang. Reg. Immunol. 1989. 2: 98-102.
10. Sydora, B. C., Jamieson, B. D., Ahmed, R. and Kronenberg, M., Intestinal intraepithelial lymphocytes respond to systemic lymphocytec choriomeningitis virus infection. Cell. Immunol. 1996. 167: 161-169.
11. Masopust, D., Vezys, V., Marzo, A. L. and Lefrancois, L., Preferential localization of effector memory cells in nonlymphoid tissue. Science 2001. 291: 2413-2417.
12. Komano, H., Fujiura, Y., Kawaguchi, M., Matsumoto, S., Hashimoto, Y., Obana, S., Mombaerts, P., Tonegawa, S., Yamamoto, H., Itohara, S., Nanno, M. and Ishikawa, H., Homeostatic regulation of intestinal epithelia by intraepithelial γδT cells. Proc. Natl. Acad. Sci. USA 1995. 92: 6147-6151.
13. Yaguchi, K., Kayaba, S., Soga, H., Yamagishi, M., Tamura, A., Kasahara, S., Ohara, S., Satoh, J., Oka, Y., Toyota, T. and Itoh, T., DNA fragmentation and detachment of enterocytes induced by anti-CD3 mAb-activated intraepithelial lymphocytes. Cell Tissue Res. 2004. 315: 71-84.
14. Johansen, F.-E., Pekna, M., Norderhaug, I. N., Haneberg, B., Hietala, M. A., Krajci, P., Betsholtz, C. and Brandtzaeg, P., Absence of epithelial immunoglobulin transport, with increased mucosal leakiness, in polymeric immunoglobulin receptor/secretory component-deficient mice. J. Exp. Med. 1999. 190: 915-921.
15. Shimada, S., Kawaguchi-Miyashita, M., Kushiro, A., Sato, T., Nanno, M., Sako, T., Matsuoka, Y., Sudo, K., Tagawa, Y., Iwakura, Y. and Ohwaki, M., Generation of polymeric immunoglobulin receptor-deficient mouse with marked reduction of secretory IgA. J. Immunol. 1999. 163: 5367-5373.
16. Kawaguchi, M., Nanno, M., Umesaki, Y., Matsumoto, S., Okada, Y., Cai, Z., Shimamura, T., Matsuoka, Y., Ohwaki, M. and Ishikawa, H., Cytolytic activity of intestinal intraepithelial lymphocytes in germ-free mice is strain dependent and determined by T cells expressing γδ T cell antigen receptors. Proc. Natl. Acad. Sci. USA 1993. 90: 8591-8594.
17. + lymphocyte populations with different T cell receptors: A role for the gut epithelium in T cell differentiation. J. Exp. Med. 1991. 173: 471-481.
18. Suzuki, K., Oida, T., Hamada, H., Hitotsumatsu, O., Watanabe, M., Hibi, T., Yamamoto, H., Kubota, E., Kaminogawa, S. and Ishikawa, H., Gut cryptopatches: direct evidence of extrathymiic anatomical sites for intestinal T lymphopoiesis. Immunity 2000. 13: 691-702.
19. Guy-Grand, D., Azogui, O., Celli, S., Darche, S., Nussenzweig, M. C., Kourilsky, P. and Vassalli, P., Extrathymic T cell lymphopoiesis: ontogeny and contribution to gut intraepithelial lymphocytes in athymic and euthymic mice. J. Exp. Med. 2003. 197: 333-341.
20. + cells. Science 2004. 305: 248-251.
21. Sait, L., Galic, M., Strugnell, R. A. and Janssen, P. H., Secretory antibodies do not affect the composition of the bacterial microbiota in the terminal ileum of 10-week-old mice. Appl. Environ. Microbiol. 2003. 69: 2100-2109.
22. Suzuki, K., Meek, B., Doi, Y., Muramatsu, M., Chiba, T., Honjo, T. and Fagarasan, S., Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut. Proc. Natl. Acad. Sci. USA 2004. 101: 1981-1986.
23. Uren, T. K., Johansen, F.-E., Wijburg, O. L. C., Koentgen, F., Brandtzaeg, P. and Strugnell, R. A., Role of the polymeric Ig receptor in mucosal B cell homeostasis. J. Immunol. 2003. 170: 2531-2539.
24. Fagarasan, S., Muramatsu, M., Suzuki, K., Nagaoka, H., Hiai, H. and Honjo, T., Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora. Science 2002. 298: 1424-1427.
25. + intraepithelial lymphocytes of the gut in mice bearing TCR transgenes. Eur. J. Immunol. 2001. 31: 2593-602.
26. Sollid, L. M., Intraepithelial lymphocytes in Celiac disease: license to kill revealed. Immunity 2004. 21: 303-304.
27. Macpherson, A. J., Gatto, D., Sainsbury, E., Harriman, G. R., Hengartner, H. and Zinkernagel, R. M., A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria. Science 2000. 288: 2222-2226.
28. Guy-Grand, D., Cuénod-Jabri, B., Malassis-Seris, M., Selz, F. and Vassalli, P., Complexity of the mouse gut T cell immune system: identification of two distinct natural killer T cell intraepithelial lineages. Eur. J. Immunol 1996. 26: 2248-2256.
29. León, F., Roldán, E., Sanchez, L., Camarero, C., Bootello, A. and Roy, G., Human small-intestinal epithelium contains functional natural killer lymphocytes. Gastroenterology 2003. 125: 345-356.
30. + T cells. J. Immunol. 2000. 164: 2890-2896.
31. Mora, J. R., Bono, M. R., Manjunath, N., Weninger, W., Cavanagh, L. L., Rosemblatt, M. and von Andrian, U. H., Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells. Nature 2003. 424: 88-93.
32. Buzoni-Gatel, D., Debbabi, H., Moretto, M., Dimier-Poisson, I. H., Lepage, A. C., Bout, D. T. and Kasper, L. H., Intraepithelial lymphocytes traffic to the intestine and enhance resistance to Toxoplasma gondii oral infection. J. Immunol. 1999. 162: 5846-5852.
33. Camerini, V., Panwala, C. and Kronenberg, M., Regional specialization of the mucosal immune system. Intraepithelial lymphocytes of the large intestine have a different phenotype and function than those of the small intestine. J. Immunol. 1993. 151: 1765-1776.
34. Brandtzaeg, P. and Nilssen, D. E., Mucosal aspects of primary B cell deficiency and gastrointestinal infections. Curr. Opin. Gastroenterol. 1995. 11: 532-540.
35. James, S. P., Detection of cytokine mRNA expression by PCR. In Colligan, J. E., Kruisbeek, A. M., Margulies, D. H., Shevach, E. M. and Strober, W. (Eds.) Current Protocol in Immunology. John Wiley & Sons, Inc., USA. 1992, p 10.23.1.
36. Sagara, S., Sugaya, K., Tokoro, Y., Tanaka, S., Takano, H., Kodama, H., Nakauchi, H. and Takahama, Y., B200 expression by T lymphoid progenitor cells in mouse fetal liver. J. Immunol. 1997. 158: 666-676.
37. + thymocytes with CD3 expression: evidence of T cell commitment in the thymus. Int. Immunol. 1996. 8: 1473-1481.
38. Li, Y.-S., Hayakawa, K. and Hardy, R. R., The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver. J. Exp. Med. 1993. 178: 951-960.
39. Hyodo, Y., Matsui, K., Hayashi, N., Tsutsui, H., Kashiwamura, S., Yamauchi, H., Hiroishi, K., Takeda, K., Tagawa, Y., Iwakura, Y. et al., IL-18 up-regulates perform-mediated NK activity without increasing perforin messenger RNA expression by binding to constitutively expressed IL-18 receptor. J. Immunol. 1999. 162: 1662-1668.