Ethanol stimulates the expression of fibronectin in lung fibroblasts via kinase-dependent signals that activate CREB

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 288, Issue 5 32-5, 2005, Pages

  Roman, Jesse ^a,c,d   Ritzenthaler, Jeffrey D ^a   Bechara, Rabih ^a,c   Brown, Lou Ann ^b   Guidot, David ^a,c  

^a Division of Pulmonary   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ATLANTA VA MEDICAL CENTER   (United States)

^d EMORY UNIVERSITY   (United States)

Author keywords

Camp response element binding protein; Extracellular matrix; Gene transcription; Lung injury; Nicotinic acetylcholine receptors; Signal transduction; Tissue remodeling

Indexed keywords

4 METHYLPYRAZOLE; ACETALDEHYDE; ALCOHOL; ALCOHOL DEHYDROGENASE; ALPHA BUNGAROTOXIN; BUNGAROTOXIN RECEPTOR; CELL DNA; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FIBRONECTIN; MESSENGER RNA; METHYLLCACONITINE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; PROTEIN KINASE C INHIBITOR; UNCLASSIFIED DRUG;

ACUTE LUNG INJURY; ALCOHOL CONSUMPTION; ALCOHOL METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ISOLATION; CELL STRAIN 3T3; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DNA BINDING; ENZYME INHIBITION; FIBROBLAST; GENE ACTIVATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; LUNG FIBROBLAST; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SEPSIS; SIGNAL TRANSDUCTION;

ANIMALS; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; ETHANOL; FIBROBLASTS; FIBRONECTINS; LUNG; MICE; MICE, KNOCKOUT; NIH 3T3 CELLS; PROMOTER REGIONS (GENETICS); RATS; RECEPTORS, NICOTINIC; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

EID: 17444369344     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00003.2004     Document Type: Article

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