Transcriptional regulation of the human interleukin 1β gene by fibronectin: Role of protein kinase C and activator protein 1 (AP-1)

Cytokine

Volumn 12, Issue 11, 2000, Pages 1581-1596

  Roman, Jesse ^a   Ritzenthaler, Jeffrey D ^a   Fenton, Matthew J ^b   Roser, Susanne ^a   Schuyler, William ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BOSTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Gene transcription; Integrin; Interleukins; Signal transduction; U937

Indexed keywords

ARGINYLGLYCYLASPARTIC ACID; CALPHOSTIN C; CYTOKINE; FIBRONECTIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTEGRIN; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE C; TRANSCRIPTION FACTOR AP 1;

ARTICLE; CELL ADHESION; CELL CULTURE; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE CONTROL; GENE DELETION; GENETIC REGULATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INFLAMMATION; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN INDUCTION; RNA ANALYSIS; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

EID: 0033671658     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.2000.0759     Document Type: Article

References (67)

1. Interleukin-1 and interleukin-1 antagonism
2. Eosinophil transendothelial migration induced by cytokines
3. IL-1β and prostaglandins regulate integrin mRNA expression
4. Regulation of integrin-type cell adhesion receptors by cytokines
5. Prostaglandin E2 and collagenase production by fibroblasts and synovial cells is regulated by urine-derived human interleukin 1 and inhibitors
6. Modulation of collagen synthesis in human glomerular epithelial cells by interleukin 1
7. Circulating interleukin-1 beta and tumour necrosis factor in septic shock and experimental endotoxin fever
8. Local pathological responses to slow-release recombinant interleukin-1, interleukin-2, and gamma-interferon in the mouse, and their relevance to chronic inflammatory disease
9. Detection of endogenous cytokines in sera or in lymph nodes obtained from patients with sarcoidosis
10. Macrophage and monocyte IL-1β regulation differs at multiple sites
11. Cytokine messenger RNA profiles in inflammatory bowel disease mucosa detected by polymerase chain reaction amplification
12. Regulation of Interleukin-1ra, interleukin-1α, and interleukin-1β production by human alveolar macrophages with phorbol myristate acetate, lipopolysaccharide, and interleukin-4
13. Regulation of interleukin-1 gene expression by adherence and lipopolysaccharide
14. The immediate early genes of human cytomegalovirus require only proximal promoter elements to upregulate expression of interleukin-1 beta
15. Interleukin-1
16. Cytokine regulation of human monocyte interleukin-1 (IL-1) production in vitro. Enhancement of IL-1 production by interferon (IFN) gamma, tumor necrosis factor-alpha, IL-2, and IL-1, and inhibition by IFN-alpha
17. Human monocyte inflammatory mediator gene expression is selectively regulated by adherence substrates
18. Monocyte adherence results in selective induction of novel genes sharing homology with mediators of inflammation and tissue repair
19. Fibrin matrices enhance the expression of interleukin-1β by human peripheral blood mononuclear cells. Implications for lung granulomatous inflammation
20. Pathogenesis of interstitial fibrosis in chronic purine aminonucleoside nephrosis
21. Fibronectins and fibronectin receptors in lung development, injury and repair
22. Extracellular matrix and lung inflammation
23. Fibronectin modulates the expression of interleukin-1β and its receptor antagonist in human mononuclear cells
24. Collagen-induced release of interleukin 1 from human blood mononuclear cells. Potentiation by fibronectin binding to the α5β1 integrin
25. Ligand binding to monocyte alpha 5 beta 1 integrin activates the alpha 2 beta 1 receptor via the alpha 5 subunit cytoplasmic domain and protein kinase C
26. Effects of chronic phorbol ester treatment on protein kinase C activity, content, and gene expression in the human monoblastoid U937 cell
27. Integrin-mediated cell adhesion activates mitogen-activated protein kinases
28. Integrin-dependent activation of MAP Kinase: A link to shape-dependent cell proliferation
29. A CRE/ATF-Like site in the upstream regulatory sequence of the human interleukin 1β gene is necessary for induction in U937 and THP-1 monocytic cell lines
30. Elevated levels of the α5β1 fibronectin receptor suppress the transformed phenotype of chinese hamster ovary cells
31. Affinity modulation of integrin α5β1: Regulation of the functional response to soluble fibronectin
32. Phorbol ester-induced differentiation of U937 cells enhances attachment to fibronectin and distinctly modulates the α5β1 and α4β1 fibronectin receptors
33. Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function
34. Fibronectin enhances in vitro lipopolysaccharide priming of polymorphonuclear leukocytes
35. Integrins as a primary signal transduction molecule regulating monocyte immediate-early gene induction
36. Differential modes of regulation of interleukin-1β expression by extracellular matrices
37. Differential inhibition of IL-1 and TNF-alpha mRNA expression by agents which block second messenger pathways in murine macrophages
38. Activation of distinct protein kinase C isozymes by phorbol esters: Correlation with induction of interleukin 1 beta gene expression
39. Fibronectin cell-binding domain triggered transmembrane signal transduction in human monocytes
40. Activation of protein kinase C precedes α5β1 integrin-mediated cell spreading on fibronectin
41. Beta 1 integrins signal lipid second messengers required during cell adhesion
42. Signal transduction from the extracellular matrix
43. Matrix/integrin interaction activates the mitogen-activated protein kinase, p44erk-1 and p42erk-2
44. Cell anchorage permits efficient signal transduction between Ras and its downstream kinases
45. The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation
46. Differential effects of protein kinase C inhibitors on fibronectin-induced interleukin-1β gene transcription, protein synthesis and secretion in human monocytic cells
47. Interaction of fibronectin with VLA-5 receptor on CD4 cells induces the AP-1 transcription factor
48. The megakaryocyte/platelet-specific enhancer of the α2β1 integrin gene: Two tandem AP1 sites and the mitogen-activated protein kinase signaling
49. Integrin-mediated tyrosine phosphorylation and cytokine message induction in monocytic cells. A possible signaling role for the Syk tyrosine kinase
50. Integrins and signal transduction: The road taken
51. The fibronectin receptor is organized by extracellular matrix fibronectin: Implications for oncogenic transformation and for cell recognition of fibronectin matrices
52. Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C
53. A synthetic inhibitor of the mitogen-activated protein kinase cascade
54. Subunits of IgG
55. Measurements of cell numbers by means of the endogenous enzyme hesoxaminidase: Applications to detection of lymphokines and cell surface antigens
56. Antibody affinity may influence antigenic modulation of the common acute lymphoblastic leukemia antigen in vitro
57. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction
58. Cytokine gene expression after in vivo primary immunization with goat antibody to mouse IgD antibody
59. Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni
60. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding
61. Activation of MAP Kinases by calcium-dependent and calcium-independent pathways. Stimulation by thapsigargin and epidermal growth factor
62. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells
63. Differential effects of protein kinase C inhibitors on fibronectin-induced interleukin-1β gene transcription, protein synthesis and secretion in human monocytic cells
64. Transcriptional regulation of interleukin-1β promotor via fibrinogen engagement of the CD18 integrin receptor
65. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei