Deposition of cellular fibronectin increases before stellate cell activation in rat liver during ethanol feeding

Alcoholism: Clinical and Experimental Research

Volumn 21, Issue 5, 1997, Pages 857-861

  Gillis, Sylvia E ^a   Nagy, Laura E ^a  

^a UNIVERSITY OF GUELPH   (Canada)

Author keywords

Collagen; Extracellular matrix; Fibrosis; Wound healing

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ALPHA ACTIN; COLLAGEN TYPE 1; FIBRONECTIN; LAMININ; LIPID;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL BLOOD LEVEL; ALCOHOL LIVER CIRRHOSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALORIC INTAKE; CELL ACTIVATION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; IMMUNOBLOTTING; LIPID LIVER LEVEL; LIVER FIBROSIS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STELLATE CELL;

ANIMALIA; RATTUS NORVEGICUS;

EID: 0030838746     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1997.tb03849.x     Document Type: Article

References (28)

1. Martinez-Hernandez A, Amenta PS: The hepatic extracellular matrix. II. Ontogenesis, regeneration and cirrhosis. Virchows Arch A Pathol Anat 423:77-84, 1993
2. Martinez-Hernandez A, Amenta PS: The extracellular matrix in hepatic regeneration. FASEB J 9:1401-1410, 1995
3. Gressner AM, Bachem MG: Molecular mechanisms of liver fibrogenesis - A homage to the role of activated fat-storing cells. Digestion 56:335-346, 1995
4. Raghow R: The role of extracellular matrix in postinflammatory wound healing and fibrosis. FASER J 8:823-831, 1994
5. 4-induced cirrhosis. Lab Invest 53:166-187, 1985
6. 4, induced acute damage or fibrosis. Biochim Biophys Acta 1181:266-272, 1993
7. Jarnagin WR, Rockey DC, Koteliansky VE, Wang SS, Bissell DM: Expression of variant fibronectins in wound healing: Cellular source and biological activity of the EIIIA segment in rat hepatic fibrogenesis. J Cell Biol 127:2037-2048, 1994
8. Tsukamoto H, Towner S, Ciofalo L, French S: Ethanol-induced liver fibrosis in rats fed high fat diets. Hepatology 6:814-822, 1986
9. Lieber CS, DeCarli LM: The feeding of alcohol in liquid diets: Two decades of application and 1982 update. Alcohol Clin Exp Res 6:523-531, 1982
10. Pujades C, Forsberg E, Enrich C, Johansson S: Changes in cell surface expression of fibronectin and fibronectin receptors during liver regeneration. J Cell Sci 102:815-820, 1992
11. Iles K, Nagy LE: Chronic ethanol feeding increases the quantity of G-proteins in rat liver plasma membranes. Hepatology 21:1154-1160, 1995
12. Bligh EJ, Dyer WJ: A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37:911-917, 1959
13. Canadian Council on Animal Care: Guide to the Care and Use of Experimental Animals, ed 2. Canadian Council on Animal Care, Ottawa, Ontario, 1993
14. Goldin R: Rodent models of alcoholic liver disease. Int J Exp Pathol 75:1-7, 1994
15. Hahn E, Wick G, Encev D, Timp R: Distribution of basement membrane proteins in normal and fibrotic human liver: Collagen type IV, laminin and fibronectin. Gut 21:63-71, 1980
16. Junge J, Horn T, Christoffersen P: The occurrence and significance of fibronectin in livers from chronic alcoholics. APMIS 96:56-61, 1988
17. Lieber CS: Alcohol and the liver: 1994 update. Gastroenterology 106:1085-1105, 1994
18. Moshage H, Casini A, Lieber CS: Acetaldehyde selectively stimulates collagen production in cultured rat liver fat-storing cells but not in hepatocytes. Hepatology 12:511-518, 1990
19. Casini A, Cunningham M, Rojkind M, Lieber CS: Acetaldehyde increases procollagen type I and fibronectin gene transcription in cultured rat fat-storing cells through a protein synthesis-dependent mechanism. Hepatology 13:758-765, 1991
20. Walton CM, Wu GY, Petruff CA, Clark SH, Lichtler AC, Wu CH: A collagen enhancer-promoter construct in transgenic mice is markedly stimulated by ethanol administration. Hepatology 23:310-315, 1996
21. Bernath VA, Muro AF, Vitullo AD, Bley MA, Baranao JL, Kornblihtt AR: Cyclic AMP inhibits fibronectin gene expression in a newly developed granulosa cell line by a mechanism that suppresses cAMP-responsive element dependent transcriptional activation. J Biol Chem 265:18219-18226, 1990
22. Miao S, Suri PK, Shu-Ling L, Abraham A, Cook N, Milos P, et al: Role of the cyclic AMP response element in rat fibronectin gene expression. Hepatology 17:882-890, 1993
23. Muro AF, Bernath VA, Kornblihtt AR: Interaction of the -170 cyclic AMP response element with the adjacent CCAAT box in the human fibronectin gene promoter. J Biol Chem 267:12767-12774, 1992
24. Arnon R, Esposti SD, Zern MA: Molecular biological aspects of alcohol-induced liver disease. Alcohol Clin Exp Res 19:247-256, 1995
25. Aldred A, Nagy LE: Dissociation of ethanol-induced changes in cAMP production from down stream regulation of TNF alpha production in rat Kupffer cells after chronic ethanol feeding. Submitted for publication, 1996
26. Hoffman PL, Tabakoff B: Ethanol and guanine nucleotide binding proteins: A selective interaction. FASEB J 4:2612-2622, 1990
27. Bachem MG, Sell KM, Melchior R, Kropf J, Eller T, Gressner AM: Tumor necrosis factor alpha and transforming growth factor bela-1 stimulate fibronectin synthesis and the transdifferentiation of fat-storing cells in the rat liver into myofibroblasts. Virchows Arch B Cell Pathol 63:123-130, 1993
28. Earnest DL, Abril ER, Jolley CS, Martinez F: Ethanol and diet-induced alterations in Kupffer cell function. Alcohol Alcohol 28:73-83, 1993