Genetic manipulations to study reproduction

Molecular and Cellular Endocrinology

Volumn 234, Issue 1-2, 2005, Pages 127-135

  Jorgez, Carolina J ^a   Lin, Yi Nan ^a   Matzuk, Martin M ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Cre loxP recombination; Fertility; Genetic manipulations; Knockout mouse; Reproduction; TGF superfamily

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA;

CONFERENCE PAPER; CORRELATION ANALYSIS; EMBRYO DEVELOPMENT; GENE DISRUPTION; GENE FUNCTION; GENE IDENTIFICATION; GENE MUTATION; GENE NUMBER; GENE SEQUENCE; GENE TARGETING; GENETIC MANIPULATION; GENOME; GERM CELL; HUMAN; INFERTILITY; INFERTILITY THERAPY; KNOCKOUT MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPRODUCTION; TRANSGENIC ANIMAL;

EID: 17044415252     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2004.08.015     Document Type: Conference Paper

References (81)

1. H. Ando, Y. Haruna, J. Miyazaki, M. Okabe, and Y. Nakanishi Spermatocyte-specific gene excision by targeted expression of Cre recombinase Biochem. Biophys. Res. Commun. 272 1 2000 125 128
2. R.R. Behringer, M.J. Finegold, and R.L. Cate Mullerian-inhibiting substance function during mammalian sexual development Cell 79 3 1994 415 425
3. C.S. Branda, and S. Dymecki Talking about a revolution: the impact of site-specific recombinases on genetic analyses in mice Dev. Cell. 6 1 2004 7 28
4. C.W. Brown, D.E. Houston-Hawkins, T.K. Woodruff, and M.M. Matzuk Insertion of Inhbb into the Inhba locus rescues the Inhba-null phenotype and reveals new activin functions Nat. Genet. 25 4 2000 453 457
5. F. Buchholz, P.O. Angrand, and A.F. Stewart Improved properties of FLP recombinase evolved by cycling mutagenesis Nat. Biotechnol. 16 7 1998 657 662
6. K.H. Burns, M.M. Viveiros, Y. Ren, P. Wang, F.J. DeMayo, D.E. Frail, J.J. Eppig, and M.M. Matzuk Roles of NPM2 in chromatin and nucleolar organization in oocytes and embryos Science 300 5619 2003 633 636
7. H. Chang, C.W. Brown, and M.M. Matzuk Genetic analysis of the mammalian transforming growth factor-beta superfamily Endocrinol. Rev. 23 6 2002 787 823
8. H. Chang, and M.M. Matzuk Smad5 is required for mouse primordial germ cell development Mech. Dev. 104 1-2 2001 61 67
9. C. Cho, W.D. Willis, E.H. Goulding, H. Jung-Ha, Y.C. Choi, N.B. Hecht, and E.M. Eddy Haploinsufficiency of protamine-1 or -2 causes infertility in mice Nat. Genet. 28 1 2001 82 86
10. G.S. Conway Premature ovarian failure Br. Med. Bull. 56 3 2000 643 649
11. L.J. Cushman, H.L. Burrows, A.F. Seasholtz, M. Lewandoski, N. Muzyczka, and S.A. Camper Cre-mediated recombination in the pituitary gland Genesis 28 3-4 2000 167 174
12. B. Dale, M. Marino, and M. Wilding The ins and outs of meiosis J. Exp. Zool. 285 3 1999 226 236
13. K. Del Punta, T. Leinders-Zufall, I. Rodriguez, D. Jukam, C.J. Wysocki, S. Ogawa, F. Zufall, and P. Mombaerts Deficient pheromone responses in mice lacking a cluster of vomeronasal receptor genes Nature 419 6902 2002 70 74
14. W.N. de Vries, L.T. Binns, K.S. Fancher, J. Dean, R. Moore, R. Kemler, and B.B. Knowles Expression of Cre recombinase in mouse oocytes: a means to study maternal effect genes Genesis 26 2 2000 110 112
15. T. Doetschman, R.G. Gregg, N. Maeda, M.L. Hooper, D.W. Melton, S. Thompson, and O. Smithies Targetted correction of a mutant HPRT gene in mouse embryonic stem cells Nature 330 6148 1987 576 578
16. J. Dong, D.F. Albertini, K. Nishimori, T.R. Kumar, N. Lu, and M.M. Matzuk Growth differentiation factor-9 is required during early ovarian folliculogenesis Nature 383 6600 1996 531 535
17. A.L. Durlinger, P. Kramer, B. Karels, F.H. de Jong, J.T. Uilenbroek, J.A. Grootegoed, and A.P. Themmen Control of primordial follicle recruitment by anti-Mullerian hormone in the mouse ovary Endocrinology 140 12 1999 5789 5796
18. J.A. Elvin, C. Yan, P. Wang, K. Nishimori, and M.M. Matzuk Molecular characterization of the follicle defects in the growth differentiation factor 9-deficient ovary Mol. Endocrinol. 13 6 1999 1018 1034
19. K.R. Folger, E.A. Wong, G. Wahl, and M.R. Capecchi Patterns of integration of DNA microinjected into cultured mammalian cells: evidence for homologous recombination between injected plasmid DNA molecules Mol. Cell. Biol. 2 11 1982 1372 1387
20. C. Fulop, S. Szanto, D. Mukhopadhyay, T. Bardos, R.V. Kamath, M.S. Rugg, A.J. Day, A. Salustri, V.C. Hascall, T.T. Glant, and K. Mikecz Impaired cumulus mucification and female sterility in tumor necrosis factor-induced protein-6 deficient mice Development 130 10 2003 2253 2261
21. P. Hasty, R. Ramirez-Solis, R. Krumlauf, and A. Bradley Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells Nature 350 6315 1991 243 246
22. R.H. Hoess, M. Ziese, and N. Sternberg P1 site-specific recombination: nucleotide sequence of the recombining sites Proc. Natl. Acad. Sci. U.S.A. 79 11 1982 3398 3402
23. R.W. Holdcraft, and R.E. Braun Androgen receptor function is required in Sertoli cells for the terminal differentiation of haploid spermatids Development 131 2 2004 459 467
24. T. Ito, K.T. Jessica, M. Bulger, R. Kobayashi, and J.T. Kadonaga ATP-facilitated chromatin assembly with a nucleoplasmin-like protein from Drosophila melanogaster J. Biol. Chem. 271 40 1996 25041 25048
25. S.P. Jamin, N.A. Arango, Y. Mishina, M.C. Hanks, and R.R. Behringer Requirement of Bmpr1a for Mullerian duct regression during male sexual development Nat. Genet. 32 3 2002 408 410
26. P. Jeyasuria, Y. Ikeda, S.P. Jamin, L. Zhao, D.G. De Rooij, A.P. Themmen, R.R. Behringer, and K.L. Parker Cell-specific knockout of steroidogenic factor 1 reveals its essential roles in gonadal function Mol. Endocrinol. 18 7 2004 1610 1619
27. C.J. Jorgez, M. Klysik, S.P. Jamin, R.R. Behringer, and M.M. Matzuk Granulosa cell-specific inactivation of follistatin causes female fertility defects Mol. Endocrinol. 18 4 2004 953 967
28. C. Kellendonk, F. Tronche, A.P. Monaghan, P.O. Angrand, F. Stewart, and G. Schutz Regulation of Cre recombinase activity by the synthetic steroid RU486 Nucleic Acids Res. 24 8 1996 1404 1411
29. B.T. Kile, K.E. Hentges, A.T. Clark, H. Nakamura, A.P. Salinger, B. Liu, N. Box, D.W. Stockton, R.L. Johnson, R.R. Behringer, A. Bradley, and M.J. Justice Functional genetic analysis of mouse chromosome 11 Nature 425 6953 2003 81 86
30. H. Kissel, I. Timokhina, M.P. Hardy, G. Rothschild, Y. Tajima, V. Soares, M. Angeles, S.R. Whitlow, K. Manova, and P. Besmer Point mutation in kit receptor tyrosine kinase reveals essential roles for kit signaling in spermatogenesis and oogenesis without affecting other kit responses EMBO J. 19 6 2000 1312 1326
31. M.R. Kuehn, A. Bradley, E.J. Robertson, and M.J. Evans A potential animal model for Lesch-Nyhan syndrome through introduction of HPRT mutations into mice Nature 326 6110 1987 295 298
32. K.M. Kwan Conditional alleles in mice: practical considerations for tissue-specific knockouts Genesis 32 2 2002 49 62
33. K.A. Lawson, N.R. Dunn, B.A. Roelen, L.M. Zeinstra, A.M. Davis, C.V. Wright, J.P. Korving, and B.L. Hogan Bmp4 is required for the generation of primordial germ cells in the mouse embryo Genes Dev. 13 4 1999 424 436
34. C. Lecureuil, I. Fontaine, P. Crepieux, and F. Guillou Sertoli and granulosa cell-specific Cre recombinase activity in transgenic mice Genesis 33 3 2002 114 118
35. M. Lewandoski Conditional control of gene expression in the mouse Nat. Rev. Genet. 2 10 2001 743 755
36. M. Lewandoski, K.M. Wassarman, and G.R. Martin Zp3-cre a transgenic mouse line for the activation or inactivation of loxP-flanked target genes specifically in the female germ line Curr. Biol. 7 2 1997 148 151
37. B.J. Libby, R. De La Fuente, M.J. O'Brien, K. Wigglesworth, J. Cobb, A. Inselman, S. Eaker, M.A. Handel, J.J. Eppig, and J.C. Schimenti The mouse meiotic mutation Mei1 disrupts chromosome synapsis with sexually dimorphic consequences for meiotic progression Dev. Biol. 242 2 2002 174 187
38. N. Liu, D.A. Dansereau, and P. Lasko Fat facets interacts with vasa in the Drosophila pole plasm and protects it from degradation Curr Biol. 13 21 2003 1905 1909
39. R.S. Makar, and T.L. Toth The evaluation of infertility Am. J. Clin. Pathol. 117 Suppl. 2002 S95 S103
40. M.M. Matzuk, M.J. Finegold, J.G. Su, A.J. Hsueh, and A. Bradley Alpha-inhibin is a tumour-suppressor gene with gonadal specificity in mice Nature 360 6402 1992 313 319
41. M.M. Matzuk, T.R. Kumar, and A. Bradley Different phenotypes for mice deficient in either activins or activin receptor type II Nature 374 6520 1995 356 360
42. M.M. Matzuk, and D.J. Lamb Genetic dissection of mammalian fertility pathways Nat. Cell. Biol. 4 Suppl. 2002 s41 s49
43. M.M. Matzuk, N. Lu, H. Vogel, K. Sellheyer, D.R. Roop, and A. Bradley Multiple defects and perinatal death in mice deficient in follistatin Nature 374 6520 1995 360 363
44. M. McLeod, S. Craft, and J.R. Broach Identification of the crossover site during FLP-mediated recombination in the Saccharomyces cerevisiae plasmid 2 microns circle Mol. Cell. Biol. 6 10 1986 3357 3367
45. A.D. Mills, R.A. Laskey, P. Black, and E.M. De Robertis An acidic protein which assembles nucleosomes in vitro is the most abundant protein in Xenopus oocyte nuclei J. Mol. Biol. 139 3 1980 561 568
46. Y. Mishina, R. Rey, M.J. Finegold, M.M. Matzuk, N. Josso, R.L. Cate, and R.R. Behringer Genetic analysis of the Mullerian-inhibiting substance signal transduction pathway in mammalian sexual differentiation Genes Dev. 10 20 1996 2577 2587
47. T. Noma, Y. Kanai, M. Kanai-Azuma, M. Ishii, M. Fujisawa, M. Kurohmaru, H. Kawakami, S.A. Wood, and Y. Hayashi Stage- and sex-dependent expressions of Usp9x, an X-linked mouse ortholog of Drosophila Fat facets, during gonadal development and oogenesis in mice Mech. Dev. 119 2002 S91 S95
48. S. O'Gorman, N.A. Dagenais, M. Qian, and Y. Marchuk Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells Proc. Natl. Acad. Sci. U.S.A. 94 26 1997 14602 14607
49. R.D. Palmiter, and R.L. Brinster Germ-line transformation of mice Annu. Rev. Genet. 20 1986 465 499
50. A. Rajkovic, J.H. Lee, C. Yan, and M.M. Matzuk The ret finger protein-like 4 gene, Rfpl4, encodes a putative E3 ubiquitin-protein ligase expressed in adult germ cells Mech. Dev. 112 1-2 2002 173 177
51. A. Rajkovic, M.S.C. Yan, M. Klysik, and M. Matzuk Discovery of germ cell-specific transcripts by expressed sequence tag database analysis Fertil. Steril. 76 3 2001 550 554
52. R. Ramirez-Solis, P. Liu, and A. Bradley Chromosome engineering in mice Nature 378 6558 1995 720 724
53. T.L. Rankin, J.S. Coleman, O. Epifano, T. Hoodbhoy, S.G. Turner, P.E. Castle, E. Lee, R. Gore-Langton, and J. Dean Fertility and taxon-specific sperm binding persist after replacement of mouse sperm receptors with human homologs Dev. Cell. 5 1 2003 33 43
54. S. Settle, P. Marker, K. Gurley, A. Sinha, A. Thacker, Y. Wang, K. Higgins, G. Cunha, and D.M. Kingsley The BMP family member Gdf7 is required for seminal vesicle growth, branching morphogenesis, and cytodifferentiation Dev. Biol. 234 1 2001 138 150
55. D.R. Shimshek, J. Kim, M.R. Hubner, D.J. Spergel, F. Buchholz, E. Casanova, A.F. Stewart, P.H. Seeburg, and R. Sprengel Codon-improved Cre recombinase (iCre) expression in the mouse Genesis 32 1 2002 19 26
56. L.M. Silver Mouse Genetics Concepts and Applications 1995 University Press Oxford
57. O. Smithies, R.G. Gregg, S.S. Boggs, M.A. Koralewski, and R.S. Kucherlapati Insertion of DNA sequences into the human chromosomal beta-globin locus by homologous recombination Nature 317 6034 1985 230 234
58. S.M. Soyal, A. Mukherjee, K.Y. Lee, J. Li, H. Li, F.J. Demayo, and J.P. Lydon Cre-mediated recombination in cell lineages that express the progesterone receptor Genesis 41 2 2005 58 66
59. N. Suzumori, C. Yan, M.M. Matzuk, and A. Rajkovic Nobox is a homeobox-encoding gene preferentially expressed in primordial and growing oocytes Mech. Dev. 111 1-2 2002 137 141
60. S.S. Tanaka, Y. Toyooka, R. Akasu, Y. Katoh-Fukui, Y. Nakahara, R. Suzuki, M. Yokoyama, and T. Noce The mouse homolog of Drosophila vasa is required for the development of male germ cells Genes Dev. 147 7 2000 841 853
61. K.R. Thomas, and M.R. Capecchi Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells Cell 51 3 1987 503 512
62. K.D. Tremblay, N.R. Dunn, and E.J. Robertson Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation Development 128 18 2001
63. M. Tsuda, Y. Sasaoka, M. Kiso, K. Abe, S. Haraguchi, S. Kobayashi, and Y. Saga Conserved role of nanos proteins in germ cell development Science 301 5637 2003 1239 1241
64. L. van der Weyden, D.J. Adams, and A. Bradley Tools for targeted manipulation of the mouse genome Physiol. Genom. 11 3 2002 133 164
65. S. Varani, J.A. Elvin, C. Yan, J. DeMayo, F.J. DeMayo, H.F. Horton, M.C. Byrne, and M.M. Matzuk Knockout of pentraxin 3, a downstream target of growth differentiation factor-9, causes female subfertility Mol. Endocrinol. 16 6 2002 1154 1167
66. A. Vassalli, M.M. Matzuk, H.A. Gardner, K.F. Lee, and R. Jaenisch Activin/inhibin beta B subunit gene disruption leads to defects in eyelid development and female reproduction Genes Dev. 8 4 1994 414 427
67. F. Vidal, J. Sage, F. Cuzin, and M. Rassoulzadegan Cre expression in primary spermatocytes: a tool for genetic engineering of the germ line Mol. Reprod. Dev. 51 3 1998 274 280
68. J.O. Ward, L.G. Reinholdt, S.A. Hartford, L.A. Wilson, R.J. Munroe, K.J. Schimenti, B.J. Libby, M. O'Brien, J.K. Pendola, J. Eppig, and J.C. Schimenti Toward the genetics of mammalian reproduction: induction and mapping of gametogenesis mutants in mice Biol. Reprod. 69 5 2003 1615 1625
69. P. Weber, M. Schuler, C. Gerard, M. Mark, D. Metzger, and P. Chambon Temporally controlled site-specific mutagenesis in the germ cell lineage of the mouse testis Biol. Reprod. 68 2 2003 553 559
70. X. Wu, P. Wang, C.A. Brown, C.A. Zilinski, and M.M. Matzuk Zygote arrest 1 (Zar1) is an evolutionarily conserved gene expressed in vertebrate ovaries Biol. Reprod. 69 3 2003 861 867
71. W. Yan, L. Ma, K.H. Burns, and M.M. Matzuk HILS1 is a spermatid-specific linker histone H1-like protein implicated in chromatin remodeling during mammalian spermiogenesis Proc. Natl. Acad. Sci. U.S.A. 100 18 2003 10546 10551
72. W. Yan, L. Ma, K.H. Burns, and M.M. Matzuk Haploinsufficiency of kelch-like protein homolog 10 causes infertility in male mice Proc. Natl. Acad. Sci. U.S.A. 101 20 2004 7793 7798
73. W. Yan, A. Rajkovic, M.M. Viveiros, K.H. Burns, J.J. Eppig, and M.M. Matzuk Identification of Gasz, an evolutionarily conserved gene expressed exclusively in germ cells and encoding a protein with four ankyrin repeats, a sterile-alpha motif, and a basic leucine zipper Mol. Endocrinol. 16 6 2002 1168 1184
74. C. Yan, P. Wang, J. DeMayo, F.J. DeMayo, J.A. Elvin, C. Carino, S.V. Prasad, S.S. Skinner, and Dunbar Synergistic roles of bone morphogenetic protein 15 and growth differentiation factor 9 in ovarian function Mol. Endocrinol. 15 6 2001 854 866
75. S.E. Yi, P.S. LaPolt, B.S. Yoon, J.Y. Chen, J.K. Lu, and K.M. Lyons The type I BMP receptor BmprIB is essential for female reproductive function Proc. Natl. Acad. Sci. U.S.A. 98 14 2001 7994 7999
76. Y. Ying, X. Liu, A. Marble, K.A. Lawson, and G.Q. Zhao Requirement of Bmp8b for the generation of primordial germ cells in the mouse Mol. Endocrinol. 14 7 2000 1053 1063
77. Y. Yu, and A. Bradley Engineering chromosomal rearrangements in mice Nat. Rev. Genet. 2 10 2001 780 790
78. G.Q. Zhao, K. Deng, P.A. Labosky, L. Liaw, and B.L. Hogan The gene encoding bone morphogenetic protein 8B is required for the initiation and maintenance of spermatogenesis in the mouse Genes Dev. 10 13 1996 1657 1669
79. G.Q. Zhao, L. Liaw, and B.L. Hogan Bone morphogenetic protein 8A plays a role in the maintenance of spermatogenesis and the integrity of the epididymis Development 125 6 1998 1103 1112
80. B. Zheng, M. Sage, E.A. Sheppeard, V. Jurecic, and A. Bradley Engineering mouse chromosomes with Cre-loxP: range, efficiency, and somatic applications Mol. Cell. Biol. 20 2 2000 648 655
81. Z. Zhou, D. Wang, X.J. Wang, and D.R. Roop In utero activation of K5.CrePR1 induces gene deletion Genesis 32 2 2002 191 192