Effects of flavonoids on cisplatin-induced apoptosis of HL-60 and L1210 leukemia cells

Leukemia Research

Volumn 27, Issue 1, 2003, Pages 65-72

  Čipák, Luboš ^a   Rauko, Peter ^a   Miadoková, Eva ^b   Čipáková, Ingrid ^c   Novotný, Ladislav ^d  

^a CANCER RESEARCH INSTITUTE   (Slovakia)

^b Physics and Informatics   (Slovakia)

^c INSTITUTE OF MOLECULAR BIOLOGY   (Armenia)

^d KUWAIT UNIVERSITY   (Kuwait)

Author keywords

Apoptosis; Chrysin; Cisplatin; Galangin; HL 60; L1210; Quercetin

Indexed keywords

CHRYSIN; CISPLATIN; DNA FRAGMENT; FLAVONOID; GALANGIN; QUERCETIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CELL STRAIN HL 60; CELL VIABILITY; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DRUG ACTIVITY; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; DRUG SENSITIVITY; DRUG STRUCTURE; HUMAN; HUMAN CELL; LEUKEMIA; LEUKEMIA L 1210; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; QUANTITATIVE ANALYSIS;

ANIMALS; APOPTOSIS; CISPLATIN; DNA FRAGMENTATION; DNA, NEOPLASM; DRUG INTERACTIONS; FLAVONOIDS; HL-60 CELLS; HUMANS; LEUKEMIA L1210; MICE; MOLECULAR STRUCTURE; QUERCETIN; TUMOR CELLS, CULTURED;

EID: 0037212377     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0145-2126(02)00063-2     Document Type: Article

References (29)

1. Stavric B. Antimutagens and anticarcinogens in foods. Food Chem. Toxicol. 32:1994;79.
2. Agullo G., Gamet-Payrastre L., Manenti S., Viala C., Rémésy C., Chap H.et al. Relationship between flavonoid structure and inhibition of phosphatidyl-inositol-3 kinase: a comparison with tyrosine kinase and protein kinase C inhibition. Biochem. Pharma. 53:1997;1649.
3. Lee Y.J., Erdos G., Hou Z., Kim S.H., Kim J.H., Cho J.M.et al. Mechanism of quercetin-induced suppression and delay of heat shock gene expression and thermotolerance development in HT-29 cells. Mol. Cell Biochem. 137:1994;141.
4. Kang T., Liang N. Studies on the inhibitory effects of quercetin on the growth of HL-60 leukemia cells. Biochem. Pharma. 54:1997;1013.
5. Lepley D.M., Pelling J.C. Induction of P21/WAF 1 and G1 cell-cycle arrest by the chemopreventive agent apigenin. Mol. Carcinogen. 19:1997;74.
6. Lepley D.M., Li B., Birt D.F., Pelling J.C. The chemopreventive flavonoid apigenin induces G2/M arrest in keratynocytes. Carcinogenesis. 17:1996;2367.
7. Scambia G., Ranelletti F.O., Panici B., Piantelli M., De Vincenzo R., Ferrandina G.et al. Quercetin induces type-II estrogen-binding sites in estrogen-receptor negative (MDA6MB231) and estrogen-receptor-positive (MCF7) human breast-cancer cell lines. Int. J. Cancer. 54:1993;462.
8. Kuntz S., Wenzel U., Daniel H. Comparative analysis of the effects of flavonoids on proliferation, cytotoxicity, and apoptosis in human colon cancer cell lines. Eur. J. Nutr. 38:1999;133.
9. Wang I.K., Lin-Shiau S.Y., Lin J.K. Induction of apoptosis by apigenin and related flavonoids through cytochrome c release and activation of caspase-9 and caspase-3 in leukaemia HL-60 cells. Eur. J. Cancer. 35:1999;1517.
10. Wenzel U., Kuntz S., Brendel M.D., Daniel H. Dietary flavone is a potent apoptosis inducer in human colon carcinoma cells. Cancer Res. 60:2000;3823.
11. Scambia G., Ranelletti F.O., Benedetti Panici P., Bonanno G., De Vincenzo R., Piantelli M.et al. Synergistic antiproliferative activity of quercetin and cisplatin on ovarian cancer cell growth. Anticancer Drugs. 1:1990;45.
12. Scambia G., Ranelletti F.O., Panici P.B., De Vincenzo R., Bonanno G., Ferrandina G.et al. Quercetin potentiates the effect of adriamycin in a multidrug-resistant MCF-7 human breast-cancer cell line: P-glycoprotein as a possible target. Cancer Chemother. Pharmacol. 34:1994;459.
13. Courage C., Budworth J., Gescher A. Comparison of ability of protein kinase C inhibitors to arrest cell growth and to alter cellular protein kinase C localization. Br. J. Cancer. 71:1995;697.
14. Carmichael J., Degraff W.G., Gazdar A.F., Minna J.D., Mitchell J.B. Evaluation of tetrazolium-based semiautomated colorometric assays: assessment of chemisensitivity Testing. Cancer Res. 47:1987;936.
15. Szekeres T., Fritzer M., Strobl H., Gharehbaghi K., Findenig G., Elford H.L.et al. Synergistic growth inhibitory and differentiating effects of trimidox and tiazofurin in human promyelocytic leukemia HL-60 cells. Blood. 84:1994;4316.
16. Chou T.C., Talalay P. Analysis of combined drug effects: a new look at a very old problem. Trends Pharmacol. Sci. 4:1983;450.
17. Evans D.L., Tilby M., Dive C. Differential sensitivity to the induction of apoptosis by cisplatin in proliferating and quiescent immature rat thymocytes is independent of the levels of drug accumulation and DNA adduct formation. Cancer Res. 54:1994;1596.
18. Rauko P., Novotny L., Dovinova I., Hunakova L., Szekeres T., Jayaram H.N. Antitumor activity of benzamide riboside and its combination with cisplatin and staurosporine. Eur. J. Pharm. Sci. 12:2001;387.
19. Heo M.Y., Sohn S.J., Au W.W. Anti-genotoxicity of galangin as a cancer chemopreventive agent candidate. Mutat. Res. 488:2001;135.
20. Čipak L., Miadokova E., Dingova H., Kogan G., Novotny L., Rauko P. Comparative DNA protectivity and antimutagenicity studies using DNA-topology and Ames assays. Toxicol. In Vitro. 15:2001;677.
21. Romanova D., Vachalkova A., Čipak L., Ovesna Z., Rauko P. Study of antioxidant effect of apigenin, luteolin and quercetin by DNA protective method. Neoplasma. 48:2001;104.
22. Rauko P., Sedlak J., Duraj J., Szekeres M.F., Novotný L. Pentoxifylline stimulates drug-induced apoptosis in leukemic cells. Neoplasma. 45:1998;296.
23. Sohn S.J., Huh I.H., Au W.W., Heo M.Y. Antigenotoxicity of galangin against N-methyl-N-nitrosourea. Mutat. Res. 402:1998;231.
24. Quadri S.A., Quadri A.N., Hahn M.E., Mann K.K., Sherr D.H. The bioflavonoid galangin blocks aryl hydrocarbon receptor activation and polycyclic aromatic hydrocarbon-induced pre-B-cell apoptosis. Mol. Pharmacol. 58:2000;515.
25. Cifone M.G., Migliorati G., Parroni R., Marchetti C., Millimaggi D., Santoni A.et al. Dexamethasone-induced thymocyte apoptosis: Apoptotic signal involves the sequential activation of phosphoinositide-specific phospholipase C, acidic sphingomyelinase, and caspases. Blood. 93:1999;2282.
26. Kuhlmann M.K., Horsch E., Burkhardt G., Wagner M., Kohler H. Reduction of cisplatin toxicity in cultured renal tubular cells by the bioflavonoid quercetin. Arch Toxicol. 72:1998;536.
27. Cross H.J., Tilby M., Chipman J.K., Ferry D.R., Gescher A. Effect of quercetin on the genotoxic potential of cisplatin. Int. J. Cancer. 66:1996;404.
28. Hofmann J., Doppler W., Jakob A., Maly K., Posch L., Uberall F.et al. Enhancement of the antiproliferative effect of cis-diamminedichloro-platinum(II) and nitrogen mustard by inhibitors of protein kinase C. Int. J. Cancer. 42:1988;382.
29. Hofmann J., Fiebig H.H., Winterhalter B.R., Berger D.P., Grunicke H. Enhancement of the antiproliferative activity of cis-diamminedichloroplatinum(II) by quercetin. Int. J. Cancer. 45:1990;536.