Therapeutic applications of heat shock proteins and molecular chaperones

Expert Opinion on Therapeutic Patents

Volumn 11, Issue 7, 2001, Pages 1153-1160

  Clark, J I ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Hsp; Immunogenicity; Molecular chaperone; Peptide binding; Protein aggregation diseases; Protein folding diseases

Indexed keywords

1,3 DIOXOLANE DERIVATIVE; CHAPERONE; GELDANAMYCIN; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 60; HEAT SHOCK PROTEIN 65; HEAT SHOCK PROTEIN 70; HERBIMYCIN A; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; VIRUS ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; AUTOIMMUNE DISEASE; CANCER; CELL PROTECTION; CYTOTOXICITY; DIABETES MELLITUS; DRUG STRUCTURE; GRAFT REJECTION; HUMAN; IMMUNE RESPONSE; IMMUNOGENICITY; ISCHEMIA; MOUSE; MULTIPLE SCLEROSIS; MYASTHENIA GRAVIS; NONHUMAN; OXIDATION; PATENT; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN MODIFICATION; PROTEIN PROCESSING; PROTEIN STABILITY; PROTEIN SYNTHESIS; REVIEW; SARCOMA CELL; SCLERODERMA; SJOEGREN SYNDROME; STREPTOCOCCUS INFECTION; STRESS; SYSTEMIC LUPUS ERYTHEMATOSUS; THERMAL STIMULATION; VIRUS INFECTION; WART VIRUS;

EID: 0034933417     PISSN: 13543776     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543776.11.7.1153     Document Type: Review

References (14)

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4. Immune responses to stress proteins: Applications to infectious disease and cancer
5. Heat shock proteins as immunological carriers and vaccines
6. Anti-inflammatory effect of heat shock protein induction is related to stabilization of I kappa B alpha through preventing I kappa B kinase activation in respiratory epithelial cells
7. A hsp70-2 mutation recognized by CTL on a human renal cell carcinoma
8. Inhibition of tumor necrosis factor-alpha transcription in macrophages exposed to febrile range temperature. A possible role for heat shock factor-1 as a negative transcriptional regulator
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10. Immunotherapy of tumors with autologous tumor-derived heat shock protein preparations
11. Heat shock proteins in cancer therapy
12. The heat shock paradox: Does NF-κB determine cell fate?
13. HSP70 stimulates cytokine production through a CD14 dependent pathway, demonstrating its dual role as a chaperone and cytokine
14. Stress management - Heat shock protein-70 and the regulation of apoptosis