A role for heterotrimeric GTP-binding proteins and ERK1/2 in insulin-mediated, nitric-oxide-dependent, cyclic GMP production in human umbilical vein endothelial cells

Diabetologia

Volumn 48, Issue 3, 2005, Pages 595-604

  Konopatskaya, O ^a,b   Shore, A C ^a   Tooke, J E ^a   Whatmore, J L ^a  

^a PENINSULA MEDICAL SCHOOL   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Cyclic GMP; ERK1 2; Insulin; Nitric oxide; Pertussis toxin

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CYCLIC GMP; ERBSTATIN; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; INSULIN; INSULIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PERTUSSIS TOXIN; PROTEIN TYROSINE KINASE INHIBITOR;

ARTICLE; CELL LINE; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; PRIORITY JOURNAL; UMBILICAL VEIN;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CELLS, CULTURED; CYCLIC GMP; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; FEMALE; GROWTH INHIBITORS; GROWTH SUBSTANCES; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; HYDROQUINONES; INSULIN; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NITRIC OXIDE; PERTUSSIS TOXIN; PREGNANCY; PROTEIN-TYROSINE KINASES; UMBILICAL VEINS;

EID: 16844372344     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-004-1653-7     Document Type: Article

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