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Volumn 3, Issue 3, 2000, Pages 150-156

Single- and multidrug resistance mutations to reverse transcriptase and protease inhibitors: Human immunodeficiency virus type 1-infected patients from two geographical areas in Spain

Author keywords

Antiretroviral treatment; HIV 1 genotypes; Resistance mutations; Spanish patients

Indexed keywords

ABACAVIR; ANTIRETROVIRUS AGENT; DELAVIRDINE; DIDANOSINE; EFAVIRENZ; INDINAVIR; LAMIVUDINE; NELFINAVIR; NEVIRAPINE; PROTEINASE INHIBITOR; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; SAQUINAVIR; STAVUDINE; ZIDOVUDINE;

EID: 1642633526     PISSN: 10909508     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (13)

References (50)
  • 1
    • 0004097811 scopus 로고    scopus 로고
    • Antiviral drug resistance: Issues and challenges
    • Richman DD, ed. Chichester, U.K.: John Willey & Sons Ltd.
    • Richman DD. Antiviral drug resistance: issues and challenges. In: Richman DD, ed. Antiviral drug resistance. Chichester, U.K.: John Willey & Sons Ltd., 1996:1-9.
    • (1996) Antiviral Drug Resistance , pp. 1-9
    • Richman, D.D.1
  • 2
    • 0345334246 scopus 로고    scopus 로고
    • Antiretroviral therapy for HIV infection in 1996. Recommendations of an international panel
    • Carpenter C, Fischl M, Hammer S, et al. Antiretroviral therapy for HIV infection in 1996. Recommendations of an international panel. JAMA 1996;276:146-154.
    • (1996) JAMA , vol.276 , pp. 146-154
    • Carpenter, C.1    Fischl, M.2    Hammer, S.3
  • 4
    • 0028874048 scopus 로고
    • Rapid turnover of plasma virus and CD4 lymphocytes in HIV-1 infection
    • Ho D, Neumann A, Perelson A, et al. Rapid turnover of plasma virus and CD4 lymphocytes in HIV-1 infection. Nature 1995;373:123-126.
    • (1995) Nature , vol.373 , pp. 123-126
    • Ho, D.1    Neumann, A.2    Perelson, A.3
  • 5
    • 0029967721 scopus 로고    scopus 로고
    • HIV-1 dynamics in vivo: Virion clearance rate, infected cell life span and viral generation time
    • Perelson AS, Neumann AU, Markowitz M, et al. HIV-1 dynamics in vivo: virion clearance rate, infected cell life span and viral generation time. Science 1996;271:1582-1586.
    • (1996) Science , vol.271 , pp. 1582-1586
    • Perelson, A.S.1    Neumann, A.U.2    Markowitz, M.3
  • 6
    • 0028952146 scopus 로고
    • HIV population dynamics in vivo: Implications for genetic variation, pathogenesis and therapy
    • Coffin JM. HIV population dynamics in vivo: Implications for genetic variation, pathogenesis and therapy. Science 1995;267:483-489.
    • (1995) Science , vol.267 , pp. 483-489
    • Coffin, J.M.1
  • 7
    • 0028051329 scopus 로고
    • Natural occurrence of drug resistance mutations in the reverse transcriptase of human immunodeficiency virus type 1 isolates
    • Nájera I, Richman DD, Olivares I, et al. Natural occurrence of drug resistance mutations in the reverse transcriptase of human immunodeficiency virus type 1 isolates. AIDS Res Hum Retroviruses 1994;10:1479-1488.
    • (1994) AIDS Res Hum Retroviruses , vol.10 , pp. 1479-1488
    • Nájera, I.1    Richman, D.D.2    Olivares, I.3
  • 8
    • 0028988479 scopus 로고
    • Pol gene quasiespecies of human immunodeficiency virus: Mutations associated with drug resistance in virus from patients undergoing no drug therapy
    • Nájera I, Holguín, Quiñones-Mateu ME, et al. Pol gene quasiespecies of human immunodeficiency virus: Mutations associated with drug resistance in virus from patients undergoing no drug therapy. J Virol 1995;69:25-31.
    • (1995) J Virol , vol.69 , pp. 25-31
    • Nájera, I.1    Holguín2    Quiñones-Mateu, M.E.3
  • 9
    • 9044230526 scopus 로고    scopus 로고
    • In vivo sequence diversity of the protease of human immunodeficiency virus type 1: Presence of protease inhibitor-resistant variants in untreated subjects
    • Lech WJ, Wang G, Yang YL, et al. In vivo sequence diversity of the protease of human immunodeficiency virus type 1: presence of protease inhibitor-resistant variants in untreated subjects. J Virol 1996;70:2038-2043.
    • (1996) J Virol , vol.70 , pp. 2038-2043
    • Lech, W.J.1    Wang, G.2    Yang, Y.L.3
  • 10
    • 0032562985 scopus 로고    scopus 로고
    • Public health implications of antiretroviral therapy and HIV drug resistance
    • Wainberg MA, Friedland G. Public health implications of antiretroviral therapy and HIV drug resistance. JAMA 1998;279:1977-1983.
    • (1998) JAMA , vol.279 , pp. 1977-1983
    • Wainberg, M.A.1    Friedland, G.2
  • 11
    • 0032581588 scopus 로고    scopus 로고
    • Sexual transmission of an HIV-1 variant resistant to multiple reverse-transcriptase and protease inhibitors
    • Hecht FM, Grant RM, Petropoulos CJ, et al. Sexual transmission of an HIV-1 variant resistant to multiple reverse-transcriptase and protease inhibitors. N Engl J Med 1998; 339:307-311.
    • (1998) N Engl J Med , vol.339 , pp. 307-311
    • Hecht, F.M.1    Grant, R.M.2    Petropoulos, C.J.3
  • 13
    • 0032542314 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 in the semen of men receiving highly active antiretroviral therapy
    • Zhang H, Dornadula G, Beumont M, et al. Human immunodeficiency virus type 1 in the semen of men receiving highly active antiretroviral therapy. N Engl J Med 1998,339:1803-1809.
    • (1998) N Engl J Med , vol.339 , pp. 1803-1809
    • Zhang, H.1    Dornadula, G.2    Beumont, M.3
  • 14
    • 20644470934 scopus 로고    scopus 로고
    • Evaluation of mixtures of wild type HIV-1 and HIV-1 with resistance mutations against reverse transcriptase inhibitors
    • Villahermosa ML, Contreras G, Pérez-Alvarez L, et al. Evaluation of mixtures of wild type HIV-1 and HIV-1 with resistance mutations against reverse transcriptase inhibitors. Antiviral Ther 1998;3:221-227.
    • (1998) Antiviral Ther , vol.3 , pp. 221-227
    • Villahermosa, M.L.1    Contreras, G.2    Pérez-Alvarez, L.3
  • 15
    • 0031046755 scopus 로고    scopus 로고
    • Line probe assay for rapid detection of drug-selected mutation in the human immunodeficiency virus type reverse transcriptase gene
    • Stuyver L, Wyseur A, Rombout A, et al. Line probe assay for rapid detection of drug-selected mutation in the human immunodeficiency virus type reverse transcriptase gene. Antimicrob Agents Chemother 1997;41:284-291.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 284-291
    • Stuyver, L.1    Wyseur, A.2    Rombout, A.3
  • 16
    • 0025089978 scopus 로고
    • Rapid and simple method for purification of nucleic acids
    • Boom R, Sol CJ, Salimans MM. Rapid and simple method for purification of nucleic acids. J Clin Microbiol 1990;28: 495-503.
    • (1990) J Clin Microbiol , vol.28 , pp. 495-503
    • Boom, R.1    Sol, C.J.2    Salimans, M.M.3
  • 17
    • 17344390474 scopus 로고    scopus 로고
    • Antiretroviral drug resistance testing in adults with HIV infection. Implications for clinical management
    • Hirsch MS, Conway B, Dáquila RT, et al. Antiretroviral drug resistance testing in adults with HIV infection. Implications for clinical management. JAMA 1998;279:1984-1991.
    • (1998) JAMA , vol.279 , pp. 1984-1991
    • Hirsch, M.S.1    Conway, B.2    Dáquila, R.T.3
  • 18
    • 0032547101 scopus 로고    scopus 로고
    • HIV treatment failure: Testing for resistance in clinical practice
    • Perrin L, Telenti A. HIV treatment failure: testing for resistance in clinical practice. Science 1998;280:1871-1873.
    • (1998) Science , vol.280 , pp. 1871-1873
    • Perrin, L.1    Telenti, A.2
  • 21
    • 0032195765 scopus 로고    scopus 로고
    • Fast genotypic detection of drug resistance mutations in the HIV-1 reverse transcriptase gene of treatment-naive patients
    • Fontaine E, Lambert C, Servais J, et al. Fast genotypic detection of drug resistance mutations in the HIV-1 reverse transcriptase gene of treatment-naive patients. J Hum Virol 1998;1:451-456.
    • (1998) J Hum Virol , vol.1 , pp. 451-456
    • Fontaine, E.1    Lambert, C.2    Servais, J.3
  • 27
    • 85069114752 scopus 로고    scopus 로고
    • Prevalence of HIV-1 drug resistance mutations in antiretroviral-naive patients at an inner city University of Miami HIV clinic in Miami, FL, 1997
    • June 24-27, Lake Maggire, Italy
    • Kozal M, Leahy N, Agar A, et al. Prevalence of HIV-1 drug resistance mutations in antiretroviral-naive patients at an inner city University of Miami HIV clinic in Miami, FL, 1997. Paper presented at: 2nd International Workshop on HIV Drug Resistance and Treatment Strategies; June 24-27, 1998; Lake Maggire, Italy.
    • (1998) 2nd International Workshop on HIV Drug Resistance and Treatment Strategies
    • Kozal, M.1    Leahy, N.2    Agar, A.3
  • 28
    • 85069113573 scopus 로고    scopus 로고
    • An epidemiological prospective survey assessing the prevalence in 230 HIV-1-positive antiretroviral-naive patients from the USA
    • June 23-26, San Diego, CA
    • Verbiest W, Schel P, Conant M, et al. An epidemiological prospective survey assessing the prevalence in 230 HIV-1-positive antiretroviral-naive patients from the USA. Paper presented at: 3rd International Workshop on HIV Drug Resistance and Treatment Strategies; June 23-26, 1999; San Diego, CA.
    • (1999) 3rd International Workshop on HIV Drug Resistance and Treatment Strategies
    • Verbiest, W.1    Schel, P.2    Conant, M.3
  • 29
    • 0342980400 scopus 로고    scopus 로고
    • Drug resistance mutations among HIV-1 strains from antiretroviral-naive patients in Martinique, French West Indies
    • Cesaire R, Dos Santos G, Abel S, et al. Drug resistance mutations among HIV-1 strains from antiretroviral-naive patients in Martinique, French West Indies. J Acquir Immune Defic Syndr 1999;22:401-405.
    • (1999) J Acquir Immune Defic Syndr , vol.22 , pp. 401-405
    • Cesaire, R.1    Dos Santos, G.2    Abel, S.3
  • 30
    • 7144242322 scopus 로고    scopus 로고
    • Prevalence of genotypic resistance to nucleoside analogues in antiretroviral-naive and antiretroviral-experienced HIV-infected patients in Spain
    • Gómez Cano M, Rubio A, Puig T, et al. Prevalence of genotypic resistance to nucleoside analogues in antiretroviral-naive and antiretroviral-experienced HIV-infected patients in Spain. AIDS 1998;12:1015-1020.
    • (1998) AIDS , vol.12 , pp. 1015-1020
    • Gómez Cano, M.1    Rubio, A.2    Puig, T.3
  • 31
    • 0032715140 scopus 로고    scopus 로고
    • Prevalence of drug resistance mutations in Spain among both naive and pretreated patients
    • Soriano V. Prevalence of drug resistance mutations in Spain among both naive and pretreated patients. Antiviral Ther 1999;4(suppl 3):57-63.
    • (1999) Antiviral Ther , vol.4 , Issue.3 SUPPL. , pp. 57-63
    • Soriano, V.1
  • 32
    • 0033911875 scopus 로고    scopus 로고
    • Improved conditions for extraction and amplification of human immunodeficiency virus type 1 RNA from plasma samples with low viral load
    • Villahermosa ML, Thomson MM, Vázquez de Parga, et al. Improved conditions for extraction and amplification of human immunodeficiency virus type 1 RNA from plasma samples with low viral load. J Hum Virol 2000;3:27-34.
    • (2000) J Hum Virol , vol.3 , pp. 27-34
    • Villahermosa, M.L.1    Thomson, M.M.2    Vázquez De Parga3
  • 33
    • 0029980114 scopus 로고    scopus 로고
    • Host-parasite dynamics and out-growth of virus containing a single K70R amino acid change in reverse transcriptase are responsible for the loss of human immunodeficiency virus type 1 RNA load suppression by zidovudine
    • Dejong MD, Veenstra J, Stilianakis NI, et al. Host-parasite dynamics and out-growth of virus containing a single K70R amino acid change in reverse transcriptase are responsible for the loss of human immunodeficiency virus type 1 RNA load suppression by zidovudine. Proc Natl Acad Sci U S A 1996;93:5501-5506.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 5501-5506
    • Dejong, M.D.1    Veenstra, J.2    Stilianakis, N.I.3
  • 34
    • 0033615307 scopus 로고    scopus 로고
    • HIV-1 drug resistance in newly infected individuals
    • Boden D, Hurley A, Zhang LQ, et al. HIV-1 drug resistance in newly infected individuals. JAMA 1999;282: 1135-1141.
    • (1999) JAMA , vol.282 , pp. 1135-1141
    • Boden, D.1    Hurley, A.2    Zhang, L.Q.3
  • 35
    • 0002035867 scopus 로고    scopus 로고
    • Prevalence of HIV-1 resistant to antiretroviral drugs in 81 individuals newly infected by sexual contact or injecting drug use
    • Salomón H, Wainberg MA, Brenner B, et al. Prevalence of HIV-1 resistant to antiretroviral drugs in 81 individuals newly infected by sexual contact or injecting drug use. AIDS 2000;14:F17-F23.
    • (2000) AIDS , vol.14
    • Salomón, H.1    Wainberg, M.A.2    Brenner, B.3
  • 36
    • 0030048748 scopus 로고    scopus 로고
    • Multidrug resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral therapy
    • Iversen AKN, Shafer RW, Werhrly K, et al. Multidrug resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral therapy. J Virol 1997;70:1086-1090.
    • (1997) J Virol , vol.70 , pp. 1086-1090
    • Iversen, A.K.N.1    Shafer, R.W.2    Werhrly, K.3
  • 37
    • 0031802175 scopus 로고    scopus 로고
    • Emergence of multi-dideoxynucleoside-resistante human immunodeficiency virus type 1 variants, viral sequence variation, and disease progression in patients receiving antiretroviral chemotherapy
    • Kavlick MF, Wyvill K, Yarchoan R, et al. Emergence of multi-dideoxynucleoside-resistante human immunodeficiency virus type 1 variants, viral sequence variation, and disease progression in patients receiving antiretroviral chemotherapy. J Inf Dis 1998;98:1506-1513.
    • (1998) J Inf Dis , vol.98 , pp. 1506-1513
    • Kavlick, M.F.1    Wyvill, K.2    Yarchoan, R.3
  • 38
    • 7844241226 scopus 로고    scopus 로고
    • Multiple dideoxynucleoside analogue-resistant(MddNR) HIV-1 strains isolated from patients from different European countries
    • Schmit JC, Van Laethem K, Ruiz L, et al. Multiple dideoxynucleoside analogue-resistant(MddNR) HIV-1 strains isolated from patients from different European countries. AIDS 1998;12:2005-2015.
    • (1998) AIDS , vol.12 , pp. 2005-2015
    • Schmit, J.C.1    Van Laethem, K.2    Ruiz, L.3
  • 39
    • 0033381530 scopus 로고    scopus 로고
    • Emergence of zidovudine and multidrug-resistance mutations in the HIV-1 reverse transcriptase gene in therapy naive patients receiving stavudine plus didanosine combination therapy
    • Pellegrin T, Izopet J, Reynes J, et al. Emergence of zidovudine and multidrug-resistance mutations in the HIV-1 reverse transcriptase gene in therapy naive patients receiving stavudine plus didanosine combination therapy. AIDS 1999;13:1703-1709.
    • (1999) AIDS , vol.13 , pp. 1703-1709
    • Pellegrin, T.1    Izopet, J.2    Reynes, J.3
  • 41
    • 0032991516 scopus 로고    scopus 로고
    • High prevalence of multiple drug resistance mutations in a UK HIV/AIDS patient population
    • Loveday C, Devereux H, Huckett L, et al. High prevalence of multiple drug resistance mutations in a UK HIV/AIDS patient population. AIDS 1999;13:627-628.
    • (1999) AIDS , vol.13 , pp. 627-628
    • Loveday, C.1    Devereux, H.2    Huckett, L.3
  • 42
    • 0002128855 scopus 로고    scopus 로고
    • Virological basis for HIV-1 resistance to stavudine investigated by analysis of clinical samples
    • Bloor S, Hertogs K, Desmet IR, et al. Virological basis for HIV-1 resistance to stavudine investigated by analysis of clinical samples [abstract]. Antiviral Ther 1998;3(suppl. 1):13.
    • (1998) Antiviral Ther , vol.3 , Issue.1 SUPPL. , pp. 13
    • Bloor, S.1    Hertogs, K.2    Desmet, I.R.3
  • 43
    • 0002445202 scopus 로고    scopus 로고
    • Phenotypic and genotypic analysis of stavudine-resistant isolates of HIV-1
    • Whitcomb J, Limoli K, Wrin T, et al. Phenotypic and genotypic analysis of stavudine-resistant isolates of HIV-1 [abstract]. Antiviral Ther 1998;3(suppl 1):14.
    • (1998) Antiviral Ther , vol.3 , Issue.1 SUPPL. , pp. 14
    • Whitcomb, J.1    Limoli, K.2    Wrin, T.3
  • 44
    • 0032533207 scopus 로고    scopus 로고
    • A 6-basepair insert in the reverse transcriptase gene of human immunodeficiency virus type 1 confers resistance to multiple nucleoside inhibitors
    • Winters M, Coolley K, Girard Y, et al. A 6-basepair insert in the reverse transcriptase gene of human immunodeficiency virus type 1 confers resistance to multiple nucleoside inhibitors. J Clin Invest 1998;102:1769-1775.
    • (1998) J Clin Invest , vol.102 , pp. 1769-1775
    • Winters, M.1    Coolley, K.2    Girard, Y.3
  • 45
    • 0030840407 scopus 로고    scopus 로고
    • Mutations in the pol gene of HIV-1 in infected patients, receiving didanosine and hydroxyurea combination therapy
    • de Antoni A, Foli A, Lisziewicz J, et al. Mutations in the pol gene of HIV-1 in infected patients, receiving didanosine and hydroxyurea combination therapy. J Infect Dis 1997;176:899-903.
    • (1997) J Infect Dis , vol.176 , pp. 899-903
    • De Antoni, A.1    Foli, A.2    Lisziewicz, J.3
  • 46
    • 0033552832 scopus 로고    scopus 로고
    • Insertion of two amino acids combined with changes in reverse transcriptase containing tyrosine-215 of HIV-1 resistant to multiple nucleoside analogs
    • de Jong JJ, Goudsmit J, Lukashov W, et al. Insertion of two amino acids combined with changes in reverse transcriptase containing tyrosine-215 of HIV-1 resistant to multiple nucleoside analogs. AIDS 1999;13:75-80.
    • (1999) AIDS , vol.13 , pp. 75-80
    • De Jong, J.J.1    Goudsmit, J.2    Lukashov, W.3
  • 47
    • 0033496511 scopus 로고    scopus 로고
    • Identification of insertion mutations in HIV-reverse transcriptase causing multiple drug resistance to nucleoside analogue reverse transcriptase inhibitors
    • Sugiura W, Matsuda M, Matsuda Z, et al. Identification of insertion mutations in HIV-reverse transcriptase causing multiple drug resistance to nucleoside analogue reverse transcriptase inhibitors. J Hum Virol 1999;2:146-153.
    • (1999) J Hum Virol , vol.2 , pp. 146-153
    • Sugiura, W.1    Matsuda, M.2    Matsuda, Z.3
  • 48
    • 0032724499 scopus 로고    scopus 로고
    • A novel genotype encoding a single amino acid insertion and five other substitutions between residues 64 and 74 of the reverse transcriptase confers high-level cross-resistance to nucleoside reverse transcriptase inhibitors
    • Rakik A, Ait-Khaled M, Griffin P, et al. A novel genotype encoding a single amino acid insertion and five other substitutions between residues 64 and 74 of the reverse transcriptase confers high-level cross-resistance to nucleoside reverse transcriptase inhibitors. J Acquired Immune Defic Syndr 1999;22:139-145.
    • (1999) J Acquired Immune Defic Syndr , vol.22 , pp. 139-145
    • Rakik, A.1    Ait-Khaled, M.2    Griffin, P.3
  • 49
    • 0033986107 scopus 로고    scopus 로고
    • High-level resistance to 3′-azido-3'′-deoxythimidine due to a deletion in the reverse transcriptase gene of human immunodeficiency virus type 1
    • Imamichi T, Sinha T, Imamichi H, et al. High-level resistance to 3′-azido-3'′-deoxythimidine due to a deletion in the reverse transcriptase gene of human immunodeficiency virus type 1. J Virol 2000;74:1023-1028.
    • (2000) J Virol , vol.74 , pp. 1023-1028
    • Imamichi, T.1    Sinha, T.2    Imamichi, H.3
  • 50
    • 0029824426 scopus 로고    scopus 로고
    • In vivo resistance to human immunodeficiency virus type 1 proteinase inhibitors:mutations, kinetics and frequencies
    • Jacobsen H, Hanggi M, Ott M, et al. In vivo resistance to human immunodeficiency virus type 1 proteinase inhibitors:mutations, kinetics and frequencies. J Infect Dis 1996;173:1379-1387.
    • (1996) J Infect Dis , vol.173 , pp. 1379-1387
    • Jacobsen, H.1    Hanggi, M.2    Ott, M.3


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