Differential effects of iron deficiency and underfeeding on serum levels of interleukin-10, interleukin-12p40, and interferon-gamma in mice

Cytokine

Volumn 26, Issue 2, 2004, Pages 73-81

  Kuvibidila, Solo ^a   Warrier, Raj P ^b  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOUISIANA STATE UNIV HLTH SCI C   (United States)

Author keywords

Interferon gamma; Interleukin 10; Interleukin 12; Iron deficiency; Mice; Pro inflammatory cytokines; Underfeeding

Indexed keywords

GAMMA INTERFERON; HEMOGLOBIN; INTERLEUKIN 10; INTERLEUKIN 12; IRON; PROTEIN P40;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CELLULAR IMMUNITY; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE ASSOCIATION; ENZYME IMMUNOASSAY; HEMATOCRIT; IN VIVO CULTURE; INFLAMMATION; IRON DEFICIENCY; IRON DEPLETION; IRON STORAGE; MALNUTRITION; MEASUREMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; THYMUS; THYMUS ATROPHY;

ANIMALS; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-12; INTERLEUKIN-12 SUBUNIT P40; IRON; MICE; PROTEIN SUBUNITS; SPLENOMEGALY; THYMUS GLAND;

EID: 1642619148     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2003.12.010     Document Type: Article

References (37)

1. Abbas A.K., Lichtman A.H., Pober J.S. Immunity to microbes. Abbas A.K., Lichtman A.H., Pober J.S. Cellular and molecular immunology. 1997;342-361 WB Saunders Company, Philadelphia.
2. Ahn H.J., Maruo S., Tomura M., Mu J., Hamaoka T., Nakanishi K., et al. A mechanism underlying synergy between IL-12 and IFN-γ-inducing factor in enhanced production of IFN-γ J Immunol. 159:1997;2125-2131.
3. D'Andrea A., Aste-Amezaga M., Valiante N.M., Ma X., Kubin M., Trinchieri G. Interleukin-10 (IL-10) inhibits human interferon-γ production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells. J Exp Med. 178:1993;1041-1048.
4. Dobashi K., Aihara M., Araki T., Shimizu Y., Utsugi M., Iizuka K., et al. Regulation of LPS induced IL-12 production by IFN-γ and IL-4 through intracellular glutathione in human alveolar macrophages. Clin Exp Immunol. 124:2001;290-296.
5. Isomäki P., Punnonen J. Pro- and anti-inflammatory cytokines in rheumatoid arthritis. Ann Med. 29:1997;499-507.
6. Arai T., Abe K., Matsuoka H., Yoshida M., Mori M., Goya S., et al. Introduction of the interleukin-10 gene into mice inhibited bleomycin-induced lung injury in vivo. Am J Physiol. 278:2000;L914-L922.
7. Clevemons K.V., Grunig G., Sobel R.A., Mirels L.F., Rennick D.M., Stevens D.A. Role of IL-10 in invasive aspergillosis: increased resistance of IL-10 gene knockout mice to lethal systemic aspergillosis. Clin Exp Immunol. 122:2000;186-191.
8. De Vries J.E. Immunosuppressive and anti-inflammatory properties of interleukin-10. Ann Med. 27:1995;537-541.
9. Morales G.M.A., Ausiello C.M., Guarino A., Urbani F., Spagnuolo M.I., Pozio E. Severe, protracted intestinal cryptosporidiosis associated with interferon-gamma deficiency: pediatric case report. Clin Infect Dis. 22:1996;848-850.
10. Persson S., Mikulowska A., Narula S., O'Garra A., Holmdahl R. Interleukin-10 suppresses the development of collagen type II-induced arthritis and ameliorates sustained arthritis in rats. Scand J Immunol. 44:1996;607-614.
11. Looker A.C., Dallman P.R., Carroll M.D., Gunter E.W., Johnson C.L. Prevalence of iron deficiency in the United States. J Am Med Assoc. 277:1997;973-976.
12. Kuvibidila S., Baliga B.S. Role of iron in immunity and infection. Calder P.C., Field C.J., Gill H.S. Nutrition and immune function. 2002;209-228 CAB International, New York, NY.
13. Walter T., Olivares M., Pizarro F., Munoz C. Iron, anemia, and infection. Nutr Rev. 55:1997;111-124.
14. Murray H.W. Endogenous interleukin-12 regulates acquired resistance in experimental visceral leishmaniasis. J Infect Dis. 175:1997;1477-1479.
15. Hallquist N.A., McNeil L.K., Lockwood J.F., Sherman A.R. Maternal-iron-deficiency effects on peritoneal macrophage and peritoneal natural-killer-cell cytotoxicity in rat pups. Am J Clin Nutr. 55:1992;741-746.
16. Sherman A.R., Lockwood J.F. Impaired natural killer cell activity in iron-deficient rat pups. J Nutr. 117:1987;567-571.
17. Murakawa H., Bland C.E., Willis W.T., Dallman P.R. Iron deficiency and neutrophil function: different rates of correction of depressions in oxidative burst and myeloperoxidase activity after iron treatment. Blood. 69:1987;1464-1468.
18. Prasad A.S. Effects of zinc on Th1 and Th2 cytokine shifts. J Infect Dis. 182:(Suppl 1):2000;S62-S68.
19. Zhang S., Petro T.M. The effect of moderate protein malnutrition on murine T cell cytokine production. Nutr Res. 17:1997;51-64.
20. Carman J.A., Pond L., Nashold F., Wassom D.L., Hayes C.E. Immunity to Trichinella spiralis infection in vitamin A-deficient mice. J Exp Med. 175:1992;111-120.
21. Kuvibidila S.R., Yu L., Ode E., Velez M., Gardner R., Warrier R.P. Effects of iron deficiency on the secretion of interleukin-10 by mitogen-treated and non-treated murine spleen cells. J Cell Biochem. 90:2003;278-286.
22. Omar F.O., Blakley B.R. The effects of iron deficiency and iron overload on cell-mediated immunity in the mouse. Br J Nutr. 72:1994;899-909.
23. Jason J., Archibald L.K., Nwanyanwu O.C., Bell M., Jensen R.J., Gunter E., et al. The effects of iron deficiency on lymphocyte cytokine production and activation: preservation of hepatic iron but not at all cost. Clin Exp Immunol. 126:2001;466-473.
24. Kuvibidila S.R., Porretta C. Differential effects of iron deficiency on the expression of CD80 and CD86 co-stimulatory receptors in mitogen-treated and untreated murine spleen cells. J Cell Biochem. 86:2002;571-582.
25. Kuvibidila S.R., Baliga B.S., Warrier R.P., Suskind R.M. Iron deficiency reduces the hydrolysis of cell membrane phosphatidyl-inositol 4,5 bis-phosphate during splenic lymphocyte activation in C57BL/6 mice. J Nutr. 128:1998;1077-1083.
26. Second report of Ad Hoc Committee on Standards for Nutritional Studies. J Nutr. 107:1977;1340-1348.
27. Rodak B.F. Routine laboratory evaluation of erythrocytes. Lotspeich-Steininger C.A., Stiene-Martin E.A., Koepke J.A. Clinical hematology, principles, procedures, correlations. 1992;107-123 JP Lippincott Company, Philadelphia.
28. Munro H.B. Differences among group means: oneway analysis of variance. Munro H.B., Page E.B. Statistical methods for health care research. 2nd ed. 1993;99-128 JP Lippincott Company, Philadelphia.
29. Chandra R.K. Effect of post-natal protein energy malnutrition and intrauterine growth retardation on immunity and risk of infection. Calder P.C., Fields C.J., Gill H.S. Nutrition and immune function. 2000;41-56 CAB International, New York, NY.
30. Kuvibidila S.R., Porretta C., Baliga B.S., Leiva L.E. Reduced thymocyte proliferation but not increased apoptosis as a possible cause of thymus atrophy in iron-deficient mice. Br J Nutr. 86:2001;157-162.
31. King L.E., Osati-Ashtiani F., Fraker P.J. Apoptosis plays a distinct role in the loss of precursor lymphocytes during zinc deficiency in mice. J Nutr. 132:2002;974-979.
32. Yamaguchi T., Hirakata Y., Izumikawa K., Miyazaki Y., Maesaki S., Tomono K., et al. Prolonged survival of mice with Pseudomonas aeruginosa-induced sepsis by rIL-12 modulation of IL-10 and interferon-gamma. J Med Microbiol. 49:2000;701-707.
33. Kuvibidila S.R., Velez M., Yu L., Warrier R.P., Baliga B.S. Differences in iron requirements by concanavalin A-treated and anti-CD3-treated murine splenic lymphocytes. Br J Nutr. 88:2002;67-72.
34. Fiorentino D.F., Zlotnik A., Vieira P., Mosmann T.R., Howard M., Moore K.W., et al. IL-10 acts on the antigen-presenting cells to inhibit cytokine production by TH1 cells. J Immunol. 146:1991;3444-3451.
35. Kuvibidila S., Dardenne M., Savino W., Lepault F. Influence of iron-deficiency anemia on selected thymus functions in mice: thymulin biological activity, T-cell subsets, and thymocyte proliferation. Am J Clin Nutr. 51:1990;228-232.
36. Dhur A., Galan P., Preziosi P., Hercberg S. Lymphocyte subpopulations in the thymus, lymph nodes, and spleen of iron-deficient and rehabilitated mice. J Nutr. 121:1991;1418-1424.
37. Helyar L., Sherman A.D. Moderate and severe iron deficiency lowers numbers of spleen T lymphocyte and B lymphocyte subsets in the C57BL/6 mouse. Nutr Res. 12:1992;1113-1122.